FIRST TRUST

First Trust Exchange-Traded Fund IV

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First Trust Low Duration Opportunities ETF (LMBS)


Semi-Annual Report
For the Six Months Ended
April 30, 2022





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TABLE OF CONTENTS
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               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                               SEMI-ANNUAL REPORT
                                 APRIL 30, 2022

Shareholder Letter...........................................................  1
Fund Performance Overview....................................................  2
Portfolio Management ........................................................  5
Understanding Your Fund Expenses.............................................  6
Portfolio of Investments.....................................................  7
Statement of Assets and Liabilities.......................................... 42
Statement of Operations...................................................... 43
Statements of Changes in Net Assets.......................................... 44
Financial Highlights......................................................... 45
Notes to Financial Statements................................................ 46
Additional Information....................................................... 56

                  CAUTION REGARDING FORWARD-LOOKING STATEMENTS

This report contains certain forward-looking statements within the meaning of
the Securities Act of 1933, as amended, and the Securities Exchange Act of 1934,
as amended. Forward-looking statements include statements regarding the goals,
beliefs, plans or current expectations of First Trust Advisors L.P. ("First
Trust" or the "Advisor") and its representatives, taking into account the
information currently available to them. Forward-looking statements include all
statements that do not relate solely to current or historical fact. For example,
forward-looking statements include the use of words such as "anticipate,"
"estimate," "intend," "expect," "believe," "plan," "may," "should," "would" or
other words that convey uncertainty of future events or outcomes.

Forward-looking statements involve known and unknown risks, uncertainties and
other factors that may cause the actual results, performance or achievements of
the series of First Trust Exchange-Traded Fund IV (the "Trust") described in
this report (First Trust Low Duration Opportunities ETF; hereinafter referred to
as the "Fund") to be materially different from any future results, performance
or achievements expressed or implied by the forward-looking statements. When
evaluating the information included in this report, you are cautioned not to
place undue reliance on these forward-looking statements, which reflect the
judgment of the Advisor and its representatives only as of the date hereof. We
undertake no obligation to publicly revise or update these forward-looking
statements to reflect events and circumstances that arise after the date hereof.

                        PERFORMANCE AND RISK DISCLOSURE

There is no assurance that the Fund will achieve its investment objectives. The
Fund is subject to market risk, which is the possibility that the market values
of securities owned by the Fund will decline and that the value of the Fund's
shares may therefore be less than what you paid for them. Accordingly, you can
lose money investing in the Fund. See "Risk Considerations" in the Additional
Information section of this report for a discussion of certain other risks of
investing in the Fund.

Performance data quoted represents past performance, which is no guarantee of
future results, and current performance may be lower or higher than the figures
shown. For the most recent month-end performance figures, please visit
www.ftportfolios.com or speak with your financial advisor. Investment returns,
net asset value and share price will fluctuate and Fund shares, when sold, may
be worth more or less than their original cost.

The Advisor may also periodically provide additional information on Fund
performance on the Fund's webpage at www.ftportfolios.com.

                            HOW TO READ THIS REPORT

This report contains information that may help you evaluate your investment in
the Fund. It includes details about the Fund and presents data and analysis that
provide insight into the Fund's performance and investment approach.

The statistical information that follows may help you understand the Fund's
performance compared to that of a relevant market benchmark.

It is important to keep in mind that the opinions expressed by personnel of the
Advisor are just that: informed opinions. They should not be considered to be
promises or advice. The opinions, like the statistics, cover the period through
the date on the cover of this report. The material risks of investing in the
Fund are spelled out in the prospectus, the statement of additional information,
and other Fund regulatory filings.





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SHAREHOLDER LETTER
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               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                  SEMI-ANNUAL LETTER FROM THE CHAIRMAN AND CEO
                                 APRIL 30, 2022


Dear Shareholders:

First Trust is pleased to provide you with the semi-annual report for the First
Trust Low Duration Opportunities ETF (the "Fund"), which contains detailed
information about the Fund for the six months ended April 30, 2022.

A couple of famous financial industry quotes came to mind recently as I was
sizing up the current business climate: "There's no such thing as a free lunch"
and "Don't fight the Fed!" It seems that for some, the trillions of dollars of
financial stimulus funneled into U.S. households and businesses by the Federal
government and its agencies to help mitigate the fallout stemming from the
coronavirus ("COVID-19") pandemic, which commenced sometime around February
2020, was for all intents and purposes "free money." It was not free. From the
close of February 2020 through March 2022, the Federal Reserve (the "Fed")
expanded the U.S. money supply, known as M2, by 41% to $21.81 trillion to boost
liquidity in the financial system. Normally, M2 grows around 6.0% on a
year-over-year basis. When you factor in that all this new capital was
accompanied by a breakdown of the global supply chain, there is little wonder
why inflation is rampant.

One of the more common definitions of inflation is too many dollars chasing too
few goods. The biggest downside to the supply chain bottlenecks, such as the
severe backup of container ships at some U.S. ports, is that they have markedly
reduced the flow of imported goods to retailers. The Fed has been signaling to
Americans and the rest of the globe that, after many years of artificially low
interest rates, tighter monetary policy will likely rule the day for the
foreseeable future. Higher interest rates make borrowing capital more expensive
and that should slow consumption over time, which, in turn, should bring down
inflation. Don't fight the Fed is code for don't bet against the Fed, in my
opinion. Stay tuned!

The primary job of the Fed is price stability. Its standard inflation target
rate is 2.0%. The most recent Consumer Price Index release showed that prices
were up 8.3% on a year-over-year basis as of April 30, 2022, according to data
from the U.S. Bureau of Labor Statistics. While down from 8.5% the prior month,
it is clearly elevated and that means the Fed has some work to do to with
respect to mitigating inflation. The war between Russia and Ukraine is making
the Fed's job even tougher, particularly in the areas of food and energy. Rising
costs and potential shortages could become even bigger if the COVID-19 outbreak
in China grows. These are important events to monitor. Fed Chairman Jerome
Powell has stated that the Fed is poised to raise the Federal Funds target rate
(upper bound) by 50 basis points at each of its next two meetings (set for June
and July), which would take the rate up to 2.00%. Data from CME Group indicates
that current market pricing has the rate rising to 2.75% or 3.00% by year-end.

Securities markets do not go up in a straight line and they do not just go up
year in and year out. In fact, what we have witnessed over the past couple of
decades are often referred to as boom and bust cycles. Thankfully, it has ended
up more boom than bust. Simply put, investors, not traders of the market, need
to be willing to take the bad with the good. As the various stages of an
economic cycle come and go (expansion to contraction), the markets tend to
reprice securities to reflect the current narrative. In other words, we believe
the markets essentially heal themselves - if you let them. That is an accurate
depiction of how the markets have behaved so far in 2022, in my opinion. In
response to a softening economy, the stock and bond markets have experienced
some serious downside through the first four months of this year, as measured by
the broader market indices. As of today, Brian Wesbury, Chief Economist at First
Trust, is not forecasting a recession for the U.S. in 2022 or 2023. Whether he
is proven right or wrong, we encourage investors to stay the course.

Thank you for giving First Trust the opportunity to play a role in your
financial future. We value our relationship with you and will report on the Fund
again in six months.

Sincerely,

/s/ James A. Bowen

James A. Bowen
Chairman of the Board of Trustees
Chief Executive Officer of First Trust Advisors L.P.


                                                                          Page 1





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FUND PERFORMANCE OVERVIEW (UNAUDITED)
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FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

The primary investment objective of the First Trust Low Duration Opportunities
ETF (the "Fund") is to generate current income. The Fund's secondary investment
objective is to provide capital appreciation. The Fund is an actively managed
exchange-traded fund. First Trust Advisors L.P. ("First Trust" or the "Advisor")
serves as the advisor. James Snyder and Jeremiah Charles are the Fund's
portfolio managers and are jointly and primarily responsible for the day-to-day
management of the Fund's investment portfolio.

Under normal market conditions, the Fund will seek to achieve its investment
objectives by investing at least 60% of its net assets (including investment
borrowings) in mortgage-related debt securities and other mortgage-related
instruments (collectively, "Mortgage-Related Investments"). The Fund normally
expects to invest in Mortgage-Related Investments tied to residential and
commercial mortgages. Mortgage-Related Investments consist of: (1) residential
mortgage-backed securities (RMBS); (2) commercial mortgage-backed securities
(CMBS); (3) stripped mortgage-backed securities (SMBS), which are
mortgage-backed securities where mortgage payments are divided up between paying
the loan's principal and paying the loan's interest; and (4) collateralized
mortgage obligations (CMOs) and real estate mortgage investment conduits
(REMICs) where they are divided into multiple classes with each class being
entitled to a different share of the principal and/or interest payments received
from the pool of underlying assets. The Fund will limit its investment in
Mortgage-Related Investments that are neither issued nor guaranteed by the U.S.
government or its agencies or instrumentalities to 20% of its net assets
(including investment borrowings). The Fund may invest up to 40% of its net
assets (including investment borrowings), in the aggregate, in (i) cash, cash
equivalents and short-term investments and (ii) non-mortgage direct obligations
of the U.S. government and other non-mortgage securities issued and/or
guaranteed by the U.S. government or its agencies or instrumentalities. The Fund
may also invest up to 5% of its net assets (including investment borrowings) in
asset-backed securities ("ABS") (other than Mortgage-Related Investments) that
are not issued and/or guaranteed by Government Entities. However, the Fund's
investments in (a) Mortgage-Related Investments that are not issued and/or
guaranteed by Government Entities and (b) ABS may not, in the aggregate, exceed
20% of the Fund's net assets (including investment borrowings). Although the
Fund intends to invest primarily in investment grade securities, the Fund may
invest up to 20% of its net assets (including investment borrowings) in
securities of any credit quality, including securities that are below investment
grade, which are also known as high yield securities, or commonly referred to as
"junk" bonds, or unrated securities that have not been judged by the advisor to
be of comparable quality to rated investment grade securities.



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PERFORMANCE
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                                                                             AVERAGE ANNUAL                 CUMULATIVE
                                                                              TOTAL RETURNS                TOTAL RETURNS
                                              6 Months      1 Year       5 Years      Inception       5 Years      Inception
                                               Ended         Ended        Ended       (11/4/14)        Ended       (11/4/14)
                                              4/30/22       4/30/22      4/30/22      to 4/30/22      4/30/22      to 4/30/22
                                                                                                    
FUND PERFORMANCE
NAV                                            -2.36%       -2.74%        1.10%         2.25%          5.60%         18.13%
Market Price                                   -2.50%       -2.92%        1.05%         2.24%          5.39%         18.04%

INDEX PERFORMANCE
ICE BofA 1-5 Year US Treasury
   & Agency Index                              -4.18%       -4.68%        0.92%         0.99%          4.71%          7.62%
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Total returns for the period since inception are calculated from the inception
date of the Fund. "Average Annual Total Returns" represent the average annual
change in value of an investment over the period indicated. "Cumulative Total
Returns" represent the total change in value of an investment over the periods
indicated.

The Fund's per share net asset value ("NAV") is the value of one share of the
Fund and is computed by dividing the value of all assets of the Fund (including
accrued interest and dividends), less all liabilities (including accrued
expenses and dividends declared but unpaid), by the total number of outstanding
shares. The price used to calculate market return ("Market Price") is determined
by using the midpoint of the national best bid and offer price ("NBBO") as of
the time that the Fund's NAV is calculated. Under SEC rules, the NBBO consists
of the highest displayed buy and lowest sell prices among the various exchanges
trading the Fund at the time the Fund's NAV is calculated. Prior to January 1,
2019, the price used was the midpoint between the highest bid and the lowest
offer on the stock exchange on which shares of the Fund were listed for trading
as of the time that the Fund's NAV was calculated. Since shares of the Fund did
not trade in the secondary market until after its inception, for the period from
inception to the first day of secondary market trading in shares of the Fund,
the NAV of the Fund is used as a proxy for the secondary market trading price to
calculate market returns. NAV and market returns assume that all distributions
have been reinvested in the Fund at NAV and Market Price, respectively.

An index is a statistical composite that tracks a specified financial market or
sector. Unlike the Fund, the index does not actually hold a portfolio of
securities and therefore does not incur the expenses incurred by the Fund. These
expenses negatively impact the performance of the Fund. Also, market returns do
not include brokerage commissions that may be payable on secondary market
transactions. If brokerage commissions were included, market returns would be
lower. The total returns presented reflect the reinvestment of dividends on
securities in the index. The returns presented do not reflect the deduction of
taxes that a shareholder would pay on Fund distributions or the redemption or
sale of Fund shares. The investment return and principal value of shares of the
Fund will vary with changes in market conditions. Shares of the Fund may be
worth more or less than their original cost when they are redeemed or sold in
the market. The Fund's past performance is no guarantee of future performance.


Page 2





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FUND PERFORMANCE OVERVIEW (UNAUDITED) (CONTINUED)
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FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

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                                            % OF NET
FUND ALLOCATION                              ASSETS
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U.S. Government Agency Mortgage-
   Backed Securities                          85.6%
Mortgage-Backed Securities                    13.3
Asset-Backed Securities                        4.6
Exchange-Traded Funds                          0.0*
Money Market Funds                             8.0
Put Options Purchased                          0.0*
U.S. Government Agency Mortgage-
   Backed Securities Sold Short              (21.2)
Written Options                               (0.0)*
Net Other Assets and Liabilities(1)            9.7
                                            -------
     Total                                   100.0%
                                            =======

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                                        % OF TOTAL LONG
                                          FIXED-INCOME
CREDIT QUALITY(3)                      INVESTMENTS & CASH
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Government and Agency                         70.7%
AAA                                            3.5
AA+                                            0.2
AA                                             0.3
A                                              0.3
A-                                             0.2
BBB                                            0.6
BBB-                                           0.2
BB                                             0.0*
BB-                                            0.2
B-                                             0.1
Not Rated                                      9.1
Cash and Cash Equivalents                     14.6
                                            -------
     Total                                  100.00%
                                            =======

*  Amount is less than 0.1%.


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                                        % OF LONG-TERM
TOP TEN HOLDINGS                        INVESTMENTS(2)
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Federal National Mortgage Association,
   Pool TBA, 4.00%, 6/15/52                    4.8%
Federal National Mortgage Association,
   Pool TBA, 4.50%, 6/15/52                    4.1
Federal National Mortgage Association,
   Pool TBA, 4.00%, 7/15/52                    2.6
Federal National Mortgage Association,
   Pool TBA, 1.50%, 6/15/52                    1.3
Federal National Mortgage Association,
   Pool TBA, 3.00%, 5/15/52                    1.1
Federal Home Loan Mortgage Corporation,
   Series SNEX-2019, Class PR1, 2.50%,
   2/1/42                                      1.0
Federal National Mortgage Association,
   Pool FS1524, 2.50%, 4/1/42                  1.0
Federal National Mortgage Association,
   Pool TBA, 2.50%, 6/15/52                    1.0
Federal National Mortgage Association,
   Pool FM3047, 4.00%, 4/1/45                  0.9
Federal National Mortgage Association,
   Pool FS0697, 2.50%, 2/1/42                  0.9
                                            -------
     Total                                    18.7%
                                            =======

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WEIGHTED AVERAGE EFFECTIVE NET DURATION
-----------------------------------------------------------
April 30, 2022                             1.6 Years
High - April 30, 2022                      1.6 Years
Low - December 31, 2021                    0.7 Years


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(1)   Includes variation margin on futures contracts.

(2)   Percentages are based on the long positions only. Money market funds and
      short positions are excluded.

(3)   The ratings are by S&P Global Ratings. A credit rating is an assessment
      provided by a nationally recognized statistical rating organization
      (NRSRO), of the creditworthiness of an issuer with respect to debt
      obligations. Ratings are measured highest to lowest on a scale that
      generally ranges from AAA to D for long-term ratings and A-1+ to C for
      short-term ratings. Investment grade is defined as those issuers that have
      a long-term credit rating of BBB- or higher or a short-term credit rating
      of A-3 or higher. The credit ratings shown relate to the credit worthiness
      of the issuers of the underlying securities in the Fund, and not to the
      Fund or its shares. U.S. Treasury and U.S. Agency mortgage-backed
      securities appear under "Government and Agency." Credit ratings are
      subject to change.


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FUND PERFORMANCE OVERVIEW (UNAUDITED) (CONTINUED)
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FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)



                PERFORMANCE OF A $10,000 INITIAL INVESTMENT
                     NOVEMBER 4, 2014 - APRIL 30, 2022

            First Trust Low Duration     ICE BofA 1-5 Year US
               Opportunities ETF        Treasury & Agency Index
                                          
11/4/14             $10,000                     $10,000
10/31/15             10,362                      10,144
4/30/16              10,725                      10,256
10/31/16             11,138                      10,301
4/30/17              11,186                      10,279
10/31/17             11,274                      10,307
4/30/18              11,294                      10,205
10/31/18             11,368                      10,273
4/30/19              11,635                      10,578
10/31/19             11,923                      10,867
4/30/20              11,990                      11,290
10/31/20             12,101                      11,314
4/30/21              12,146                      11,290
10/31/21             12,099                      11,232
4/30/22              11,813                      10,762


Performance figures assume reinvestment of all distributions and do not reflect
the deduction of taxes that a shareholder would pay on Fund distributions or the
redemption or sale of Fund shares. An index is a statistical composite that
tracks a specified financial market or sector. Unlike the Fund, the index does
not actually hold a portfolio of securities and therefore does not incur the
expenses incurred by the Fund. These expenses negatively impact the performance
of the Fund. The Fund's past performance does not predict future performance.

Performance in securitized product investment strategies can be impacted from
the benefits of purchasing odd lot positions. The impact of these investments
can be particularly meaningful when funds have limited assets under management
and may not be a sustainable source of performance as a fund grows in size.

FREQUENCY DISTRIBUTION OF DISCOUNTS AND PREMIUMS

Information showing the number of days the market price of the Fund's shares was
greater (at a premium) and less (at a discount) than the Fund's net asset value
for the most recently completed year, and the most recently completed calendar
quarters since that year (or life of the Fund, if shorter) is available at
https://www.ftportfolios.com/Retail/etf/home.aspx.


Page 4





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PORTFOLIO MANAGEMENT
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               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                               SEMI-ANNUAL REPORT
                           APRIL 30, 2022 (UNAUDITED)

                                    ADVISOR

First Trust Advisors L.P. ("First Trust" or the "Advisor") is the investment
advisor to the First Trust Low Duration Opportunities ETF (the "Fund" or
"LMBS"). In this capacity, First Trust is responsible for the selection and
ongoing monitoring of the investments in the Fund's portfolio and certain other
services necessary for the management of the portfolio.

                           PORTFOLIO MANAGEMENT TEAM

JAMES SNYDER - SENIOR VICE PRESIDENT AND PORTFOLIO MANAGER
JEREMIAH CHARLES - SENIOR VICE PRESIDENT AND SENIOR PORTFOLIO MANAGER

The portfolio managers are primarily and jointly responsible for the day-to-day
management of the Fund. Each portfolio manager has served as part of the
portfolio management team of the Fund since 2014.


                                                                          Page 5





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

UNDERSTANDING YOUR FUND EXPENSES
APRIL 30, 2022 (UNAUDITED)

As a shareholder of First Trust Low Duration Opportunities ETF (the "Fund"), you
incur two types of costs: (1) transaction costs; and (2) ongoing costs,
including management fees, distribution and/or service (12b-1) fees, if any, and
other Fund expenses. This Example is intended to help you understand your
ongoing costs of investing in the Fund and to compare these costs with the
ongoing costs of investing in other funds.

The Example is based on an investment of $1,000 invested at the beginning of the
period and held through the six-month period ended April 30, 2022.

ACTUAL EXPENSES

The first line in the following table provides information about actual account
values and actual expenses. You may use the information in this line, together
with the amount you invested, to estimate the expenses that you paid over the
period. Simply divide your account value by $1,000 (for example, an $8,600
account value divided by $1,000 = 8.6), then multiply the result by the number
in the first line under the heading entitled "Expenses Paid During the Six-Month
Period" to estimate the expenses you paid on your account during this six-month
period.

HYPOTHETICAL EXAMPLE FOR COMPARISON PURPOSES

The second line in the following table provides information about hypothetical
account values and hypothetical expenses based on the Fund's actual expense
ratio and an assumed rate of return of 5% per year before expenses, which is not
the Fund's actual return. The hypothetical account values and expenses may not
be used to estimate the actual ending account balance or expenses you paid for
the period. You may use this information to compare the ongoing costs of
investing in the Fund and other funds. To do so, compare this 5% hypothetical
example with the 5% hypothetical examples that appear in the shareholder reports
of the other funds.

Please note that the expenses shown in the table are meant to highlight your
ongoing costs only and do not reflect any transactional costs such as brokerage
commissions. Therefore, the second line in the table is useful in comparing
ongoing costs only, and will not help you determine the relative total costs of
owning different funds. In addition, if these transactional costs were included,
your costs would have been higher.



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                                                                                        ANNUALIZED
                                                                                       EXPENSE RATIO    EXPENSES PAID
                                                    BEGINNING            ENDING        BASED ON THE       DURING THE
                                                  ACCOUNT VALUE      ACCOUNT VALUE       SIX MONTH        SIX MONTH
                                                 NOVEMBER 1, 2021    APRIL 30, 2022     PERIOD (a)      PERIOD (a) (b)
----------------------------------------------------------------------------------------------------------------------
                                                                                                
FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
Actual                                              $1,000.00          $  976.40           0.65%            $3.19
Hypothetical (5% return before expenses)            $1,000.00          $1,021.57           0.65%            $3.26


(a)   Annualized expense ratio and expenses paid during the six-month period do
      not include fees and expenses of the underlying funds in which the Fund
      invests.

(b)   Expenses are equal to the annualized expense ratio as indicated in the
      table multiplied by the average account value over the period (November 1,
      2021 through April 30, 2022), multiplied by 181/365 (to reflect the
      six-month period).


Page 6





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES -- 85.6%
                  COLLATERALIZED MORTGAGE OBLIGATIONS -- 30.9%
                  Federal Home Loan Mortgage Corporation
$          2,670     Series 1993-1498, Class I, 1 Mo. LIBOR + 1.15% (a)...........      1.70%       04/15/23    $          2,679
           2,591     Series 1993-1552, Class I, 10 Yr. Constant Maturity Treasury
                        Rate - 0.65% (a)..........................................      1.51%       08/15/23               2,577
          24,676     Series 1993-1579, Class PM...................................      6.70%       09/15/23              25,174
          24,803     Series 1993-1630, Class PK...................................      6.00%       11/15/23              25,402
           1,211     Series 1993-1643, Class PK...................................      6.50%       12/15/23               1,230
          70,932     Series 1994-1710, Class G, 1 Mo. LIBOR + 1.50% (a)...........      2.05%       04/15/24              71,604
           1,133     Series 1998-2089, Class PJ, IO...............................      7.00%       10/15/28                 100
           4,607     Series 1998-2102, Class Z....................................      6.00%       12/15/28               4,872
              80     Series 2001-2365, Class LO, PO...............................       (b)        09/15/31                  80
          16,605     Series 2002-2405, Class BF...................................      7.00%       03/25/24              16,970
         150,747     Series 2002-2410, Class OG...................................      6.38%       02/15/32             167,177
          94,069     Series 2002-2427, Class GE...................................      6.00%       03/15/32             101,863
         154,183     Series 2002-2437, Class SA, IO, 1 Mo. LIBOR (x) -1 +
                        7.90% (c).................................................      7.35%       01/15/29              12,406
         194,371     Series 2003-2557, Class HL...................................      5.30%       01/15/33             205,417
         103,400     Series 2003-2564, Class AC...................................      5.50%       02/15/33             109,008
         283,526     Series 2003-2574, Class PE...................................      5.50%       02/15/33             302,651
         119,292     Series 2003-2577, Class LI, IO...............................      5.50%       02/15/33              16,208
         993,000     Series 2003-2581, Class LL...................................      5.25%       03/15/33           1,044,444
          51,276     Series 2003-2586, Class TG...................................      5.50%       03/15/23              51,671
          33,856     Series 2003-2597, Class AE...................................      5.50%       04/15/33              35,016
       1,237,000     Series 2003-2613, Class LL...................................      5.00%       05/15/33           1,293,274
         255,924     Series 2003-2626, Class ZW...................................      5.00%       06/15/33             237,416
         557,914     Series 2003-2626, Class ZX...................................      5.00%       06/15/33             548,714
          27,000     Series 2003-2676, Class LL...................................      5.50%       09/15/33              28,210
         430,178     Series 2004-2771, Class NL...................................      6.00%       03/15/34             459,903
         349,141     Series 2004-2793, Class PE...................................      5.00%       05/15/34             367,825
         844,559     Series 2004-2801, Class SE, IO, 1 Mo. LIBOR (x) -1 +
                        7.05% (c).................................................      6.50%       07/15/32              84,324
         135,287     Series 2004-2835, Class QY, IO, 1 Mo. LIBOR (x) -1 +
                        7.90% (c).................................................      7.35%       12/15/32              16,473
         105,744     Series 2004-2890, Class ZA...................................      5.00%       11/15/34             111,423
         618,530     Series 2004-2891, Class ZA...................................      6.50%       11/15/34             757,900
         371,785     Series 2004-2907, Class DZ...................................      4.00%       12/15/34             371,208
       1,109,843     Series 2005-233, Class 12, IO, STRIPS........................      5.00%       09/15/35             156,905
         808,055     Series 2005-234, Class IO, IO, STRIPS........................      4.50%       10/01/35             115,048
         785,000     Series 2005-2973, Class GE...................................      5.50%       05/15/35             867,294
         117,889     Series 2005-3031, Class BI, IO, 1 Mo. LIBOR (x) -1 +
                        6.69% (c).................................................      6.14%       08/15/35              16,767
       2,250,005     Series 2005-3054, Class ZW...................................      6.00%       10/15/35           2,361,700
          22,155     Series 2005-3074, Class ZH...................................      5.50%       11/15/35              25,478
         246,599     Series 2006-238, Class 8, IO, STRIPS.........................      5.00%       04/15/36              42,405
         225,948     Series 2006-243, Class 11, IO, STRIPS (d)....................      7.00%       08/15/36              40,498
          67,909     Series 2006-3117, Class ZU...................................      6.00%       02/15/36              82,631
          24,083     Series 2006-3150, Class DZ...................................      5.50%       05/15/36              25,826
       1,230,613     Series 2006-3174, Class LF, 1 Mo. LIBOR + 0.35% (a)..........      0.90%       05/15/36           1,230,425
       2,760,979     Series 2006-3196, Class ZK...................................      6.50%       04/15/32           3,237,388
       1,295,548     Series 2006-3210, Class SA, IO, 1 Mo. LIBOR (x) -1 +
                        6.60% (c).................................................      6.05%       09/15/36             163,100
         401,388     Series 2006-3223, Class FC, 1 Mo. LIBOR + 0.55% (a)..........      0.95%       04/15/32             404,463



                        See Notes to Financial Statements                 Page 7





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Federal Home Loan Mortgage Corporation (Continued)
$        915,220     Series 2007-3262, Class KS, IO, 1 Mo. LIBOR (x) -1 +
                        6.41% (c).................................................      5.86%       01/15/37    $         57,630
          36,275     Series 2007-3274, Class B....................................      6.00%       02/15/37              38,118
         202,504     Series 2007-3322, Class NF, 1 Mo. LIBOR (x) 2,566.67 -
                        16,683.33%, 0.00% Floor (a)...............................      0.00%       05/15/37             196,272
          34,779     Series 2007-3340, Class PF, 1 Mo. LIBOR + 0.30% (a)..........      0.85%       07/15/37              34,619
          43,635     Series 2007-3349, Class MY...................................      5.50%       07/15/37              45,627
          79,081     Series 2007-3360, Class CB...................................      5.50%       08/15/37              83,569
       1,022,884     Series 2007-3370, Class FM, 1 Mo. LIBOR + 0.62% (a)..........      1.17%       10/15/47           1,039,052
          74,070     Series 2007-3380, Class FS, 1 Mo. LIBOR + 0.35% (a)..........      0.90%       11/15/36              72,135
         203,189     Series 2008-3406, Class B....................................      6.00%       01/15/38             213,014
         103,726     Series 2008-3413, Class B....................................      5.50%       04/15/37             108,415
         247,889     Series 2008-3420, Class AZ...................................      5.50%       02/15/38             263,076
         169,265     Series 2008-3448, Class SA, IO, 1 Mo. LIBOR (x) -1 +
                        6.05% (c).................................................      5.50%       05/15/38               4,594
       2,565,310     Series 2009-3522, Class SE, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.55%       04/15/39             270,924
          29,406     Series 2009-3523, Class SD, 1 Mo. LIBOR (x) -2.75 +
                        19.66% (c)................................................      8.14%       06/15/36              31,497
       1,235,831     Series 2009-3542, Class ZP...................................      5.00%       06/15/39           1,307,299
         177,000     Series 2009-3550, Class LL...................................      4.50%       07/15/39             179,396
         752,561     Series 2009-3563, Class ZP...................................      5.00%       08/15/39             825,471
       1,586,569     Series 2009-3572, Class JS, IO, 1 Mo. LIBOR (x) -1 +
                        6.80% (c).................................................      6.25%       09/15/39             135,506
          33,581     Series 2009-3585, Class QZ...................................      5.00%       08/15/39              33,026
         124,990     Series 2009-3587, Class FX, 1 Mo. LIBOR + 0.00% (a)..........      0.55%       12/15/37             113,651
         491,065     Series 2009-3593, Class F, 1 Mo. LIBOR + 0.50% (a)...........      0.73%       03/15/36             491,935
       1,343,473     Series 2009-3605, Class NC...................................      5.50%       06/15/37           1,441,357
         500,000     Series 2010-3622, Class PB...................................      5.00%       01/15/40             517,248
         421,984     Series 2010-3632, Class BS, 1 Mo. LIBOR (x) -3.33 +
                        17.50% (c)................................................     15.65%       02/15/40             483,723
         107,000     Series 2010-3645, Class WD...................................      4.50%       02/15/40             102,650
         634,855     Series 2010-3667, Class PL...................................      5.00%       05/15/40             646,960
          68,766     Series 2010-3699, Class FD, 1 Mo. LIBOR + 0.60% (a)..........      1.15%       07/15/40              69,278
         663,521     Series 2010-3704, Class ED...................................      4.00%       12/15/36             670,494
         400,000     Series 2010-3714, Class PB...................................      4.75%       08/15/40             424,008
         424,808     Series 2010-3735, Class IK, IO...............................      3.50%       10/15/25              15,635
          77,569     Series 2010-3735, Class JI, IO...............................      4.50%       10/15/30               7,994
         227,884     Series 2010-3740, Class SC, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.45%       10/15/40              35,539
         149,733     Series 2010-3770, Class GZ...................................      4.50%       10/15/40             153,067
          37,405     Series 2011-3795, Class ED...................................      3.00%       10/15/39              37,471
         600,000     Series 2011-3796, Class PB...................................      5.00%       01/15/41             633,171
         214,176     Series 2011-3819, Class ZQ...................................      6.00%       04/15/36             234,637
       3,677,067     Series 2011-3820, Class GZ...................................      5.00%       03/15/41           3,900,049
         300,000     Series 2011-3820, Class NC...................................      4.50%       03/15/41             312,928
         153,801     Series 2011-3828, Class SY, 1 Mo. LIBOR (x) -3 +
                        13.20% (c)................................................     11.54%       02/15/41             145,853
         636,419     Series 2011-3841, Class JZ...................................      5.00%       04/15/41             676,025
         103,547     Series 2011-3842, Class BS, 1 Mo. LIBOR (x) -5 +
                        22.75% (c)................................................     20.47%       04/15/41             131,090
         300,000     Series 2011-3844, Class PC...................................      5.00%       04/15/41             325,335



Page 8                  See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Federal Home Loan Mortgage Corporation (Continued)
$        507,114     Series 2011-3852, Class SW, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.45%       05/15/41    $         67,622
       3,310,252     Series 2011-3860, Class PZ...................................      5.00%       05/15/41           3,467,097
         525,000     Series 2011-3890, Class ME...................................      5.00%       07/15/41             562,165
       1,387,000     Series 2011-3895, Class PW...................................      4.50%       07/15/41           1,420,835
       1,836,677     Series 2011-3925, Class ZD...................................      4.50%       09/15/41           1,951,097
       9,805,101     Series 2011-3954, Class GS, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.45%       11/15/41           1,468,444
         360,332     Series 2012-267, Class S5, IO, STRIPS, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.45%       08/15/42              49,446
      10,618,510     Series 2012-272, Class PO, PO, STRIPS........................       (b)        08/15/42           8,794,141
       7,765,218     Series 2012-276, Class S5, IO, STRIPS, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.45%       09/15/42           1,038,161
         401,638     Series 2012-3999, Class WA (d)...............................      5.55%       08/15/40             425,975
       1,878,000     Series 2012-4000, Class PY...................................      4.50%       02/15/42           1,846,132
          45,312     Series 2012-4012, Class GC...................................      3.50%       06/15/40              45,387
          25,955     Series 2012-4015, Class KB...................................      1.75%       05/15/41              24,695
         368,907     Series 2012-4021, Class IP, IO...............................      3.00%       03/15/27              17,226
       1,125,292     Series 2012-4026, Class GZ...................................      4.50%       04/15/42           1,212,860
         637,046     Series 2012-4030, Class IL, IO...............................      3.50%       04/15/27              33,233
         653,595     Series 2012-4048, Class FJ, 1 Mo. LIBOR + 0.40% (a)..........      0.63%       07/15/37             652,225
       1,206,800     Series 2012-4054, Class AI, IO...............................      3.00%       04/15/27              53,481
       3,833,667     Series 2012-4057, Class ZC...................................      3.50%       06/15/42           3,807,584
       1,107,962     Series 2012-4077, Class TS, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.45%       05/15/41             152,397
         656,711     Series 2012-4090, Class YZ...................................      4.50%       08/15/42             677,685
          27,337     Series 2012-4097, Class ES, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.55%       08/15/42               4,209
       2,820,559     Series 2012-4097, Class SA, IO, 1 Mo. LIBOR (x) -1 +
                        6.05% (c).................................................      5.50%       08/15/42             446,685
       2,447,000     Series 2012-4098, Class PE...................................      4.00%       08/15/42           2,349,418
         289,923     Series 2012-4103, Class HI, IO...............................      3.00%       09/15/27              15,607
          34,078     Series 2012-4116, Class AS, IO, 1 Mo. LIBOR (x) -1 +
                        6.15% (c).................................................      5.60%       10/15/42               5,726
       1,192,485     Series 2012-4121, Class HI, IO...............................      3.50%       10/15/27              66,784
       1,336,638     Series 2012-4132, Class AI, IO...............................      4.00%       10/15/42             226,405
         319,937     Series 2012-4136, Class TU, IO, 1 Mo. LIBOR (x) -22.50 +
                        139.50%, 4.50% Cap (c)....................................      4.50%       08/15/42              54,909
         371,782     Series 2012-4145, Class YI, IO...............................      3.00%       12/15/27              20,478
         245,349     Series 2013-299, Class S1, IO, STRIPS, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.45%       01/15/43              38,797
       6,127,921     Series 2013-303, Class C12, IO, STRIPS.......................      4.00%       12/15/32             655,080
         348,723     Series 2013-303, Class C2, IO, STRIPS........................      3.50%       01/15/28              20,903
      13,418,765     Series 2013-303, Class C33, IO, STRIPS.......................      4.50%       01/15/43           2,509,046
       3,452,167     Series 2013-304, Class C19, IO, STRIPS.......................      5.00%       06/15/42             814,340
         271,513     Series 2013-304, Class C37, IO, STRIPS.......................      3.50%       12/15/27              12,564
       1,199,467     Series 2013-304, Class C40, IO, STRIPS.......................      3.50%       09/15/26              52,528
      11,653,496     Series 2013-311, Class PO, PO, STRIPS........................       (b)        08/15/43           9,654,320
       1,145,103     Series 2013-4151, Class DI, IO...............................      3.50%       11/15/31              51,024
       3,149,334     Series 2013-4154, Class IB, IO...............................      3.50%       01/15/28             181,728
       8,316,472     Series 2013-4170, Class CO, PO...............................       (b)        11/15/32           7,131,446
         905,000     Series 2013-4176, Class HE...................................      4.00%       03/15/43             915,328



                        See Notes to Financial Statements                 Page 9





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Federal Home Loan Mortgage Corporation (Continued)
$        732,650     Series 2013-4177, Class GL...................................      3.00%       03/15/33    $        707,728
       3,955,409     Series 2013-4193, Class AI, IO...............................      3.00%       04/15/28             239,459
         826,035     Series 2013-4193, Class PB...................................      4.00%       04/15/43             831,355
       1,210,675     Series 2013-4203, Class US, 1 Mo. LIBOR (x) -1.50 +
                        6.00% (c).................................................      5.17%       05/15/33             979,486
         500,000     Series 2013-4211, Class PB...................................      3.00%       05/15/43             475,039
          11,838     Series 2013-4226, Class NS, 1 Mo. LIBOR (x) -3 +
                        10.50% (c)................................................      9.13%       01/15/43              10,263
       1,450,000     Series 2013-4247, Class AY...................................      4.50%       09/15/43           1,532,647
         701,641     Series 2013-4261, Class GS, 1 Mo. LIBOR (x) -2.75 +
                        10.98% (c)................................................      9.46%       01/15/41             688,519
         394,901     Series 2013-4265, Class IB, IO...............................      4.50%       12/15/24              13,559
          33,796     Series 2014-4300, Class IM, IO...............................      3.00%       03/15/37                 380
         838,263     Series 2014-4314, Class CI, IO...............................      6.00%       03/15/44             192,225
       2,401,019     Series 2014-4316, Class XZ...................................      4.50%       03/15/44           2,460,083
       3,954,319     Series 2014-4347, Class YT...................................      3.50%       06/15/44           3,748,260
      24,026,220     Series 2014-4358, Class Z....................................      3.00%       06/15/44          22,611,371
      16,101,455     Series 2014-4375, Class MZ...................................      3.50%       08/15/44          15,768,622
       3,319,146     Series 2014-4387, Class IE, IO...............................      2.50%       11/15/28             160,208
         664,865     Series 2015-4503, Class MI, IO...............................      5.00%       08/15/45             120,452
         614,023     Series 2015-4512, Class W (d) (e)............................      5.34%       05/15/38             645,538
          88,657     Series 2015-4520, Class AI, IO...............................      3.50%       10/15/35               9,593
         244,355     Series 2015-4522, Class JZ...................................      2.00%       01/15/45             243,738
         273,909     Series 2016-4546, Class PZ...................................      4.00%       12/15/45             259,904
         463,659     Series 2016-4546, Class ZT...................................      4.00%       01/15/46             439,070
       6,891,954     Series 2016-4559, Class LI, IO...............................      2.50%       03/15/31             473,004
         142,323     Series 2016-4568, Class MZ...................................      4.00%       04/15/46             132,839
      12,040,654     Series 2016-4570, Class ST, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.45%       04/15/46           1,837,788
       4,587,468     Series 2016-4572, Class LI, IO...............................      4.00%       08/15/45             727,533
      14,510,109     Series 2016-4582, Class GZ...................................      3.75%       03/15/52          14,049,773
      22,420,047     Series 2016-4585, Class DS, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.45%       05/15/46           3,446,524
       6,975,536     Series 2016-4587, Class ZH...................................      4.00%       03/15/44           6,961,990
       1,478,578     Series 2016-4591, Class GI, IO...............................      4.00%       12/15/44             221,515
         944,001     Series 2016-4596, Class FL, 1 Mo. LIBOR + 0.50% (a)..........      0.73%       11/15/41             951,146
         771,702     Series 2016-4600, Class WT...................................      3.50%       07/15/36             765,332
         138,508     Series 2016-4605, Class KS, 1 Mo. LIBOR (x) -1.57 +
                        4.71% (c).................................................      4.00%       08/15/43             103,163
         239,702     Series 2016-4609, Class YI, IO...............................      4.00%       04/15/54              15,187
         341,210     Series 2016-4613, Class AF, 1 Mo. LIBOR + 1.10% (a)..........      1.65%       11/15/37             340,431
         870,822     Series 2016-4615, Class GT, 1 Mo. LIBOR (x) -4 + 16.00%,
                        4.00% Cap (c).............................................      4.00%       10/15/42             693,211
       2,145,733     Series 2016-4641, Class DI, IO...............................      5.00%       05/15/41             292,161
       1,173,000     Series 2017-4650, Class JH...................................      3.00%       01/15/47           1,033,332
      10,302,449     Series 2017-4660, Class PO, PO...............................       (b)        01/15/33           7,382,837
      17,812,190     Series 2017-4680, Class GZ...................................      3.50%       03/15/47          17,206,127
         600,000     Series 2017-4681, Class JY...................................      2.50%       05/15/47             533,902
       3,299,122     Series 2018-4774, Class SL, IO, 1 Mo. LIBOR (x) -1 +
                        6.20% (c).................................................      5.65%       04/15/48             540,236
         820,531     Series 2018-4780, Class VA...................................      4.00%       05/15/29             822,392
       2,814,279     Series 2018-4790, Class IO, IO...............................      4.50%       05/15/48             497,715



Page 10                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Federal Home Loan Mortgage Corporation (Continued)
$      5,972,566     Series 2018-4826, Class ME...................................      3.50%       09/15/48    $      5,803,311
       3,176,931     Series 2018-4833, Class PY...................................      4.00%       10/15/48           3,138,071
       8,220,088     Series 2018-4851, Class PO, PO...............................       (b)        08/15/57           6,089,375
       3,199,100     Series 2019-4872, Class BZ...................................      4.00%       04/15/49           3,115,920
       6,738,132     Series 2019-4910, Class SA, IO, 1 Mo. LIBOR (x) -1 +
                        6.05% (c).................................................      5.50%       06/15/49           1,449,492
       9,541,718     Series 2019-4938, Class BS, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.33%       12/25/49           1,515,628
      18,964,209     Series 2019-4941, Class YZ...................................      3.00%       12/25/49          18,031,634
      10,353,707     Series 2019-4943, Class NS, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.33%       01/25/50           2,363,993
       2,515,155     Series 2020-4974, Class IA, IO...............................      3.50%       12/25/49             703,761
       6,430,891     Series 2020-4988, Class IJ, IO...............................      4.50%       12/15/47           1,051,532
       5,235,038     Series 2020-4989, Class FB, 1 Mo. LIBOR + 0.35% (a)..........      0.58%       10/15/40           5,231,657
       8,898,630     Series 2020-5013, Class HI, IO...............................      5.00%       03/25/40           1,488,081
       6,027,925     Series 2020-5013, Class IQ, IO...............................      3.50%       09/25/50           1,009,592
      15,659,396     Series 2020-5023, Class AI, IO...............................      4.50%       10/25/50           3,225,994
      17,731,789     Series 2020-5034, Class IO, IO (d)...........................      1.82%       10/15/45             597,409
      18,541,666     Series 2020-5050, Class MI, IO...............................      3.50%       10/25/50           2,981,172
      32,035,840     Series 2020-5051, Class CI, IO...............................      4.00%       12/25/35           3,814,748
      25,668,714     Series 2021-5086, Class MI, IO...............................      2.50%       03/25/51           3,690,902
       8,815,818     Series 2021-5178, Class HL...................................      2.00%       01/25/52           6,947,077
      17,589,321     Series 2022-5200, Class TZ...................................      2.50%       11/25/49          14,381,787
      11,385,124     Series 2022-5208, Class HZ...................................      3.50%       03/25/52          10,644,000
      13,395,248     Series 2022-5208, Class Z....................................      3.00%       04/25/52          11,620,555
      11,812,528     Series 2022-5220, Class KZ (f)...............................      4.00%       02/25/51          11,929,730
       4,870,948     Series 2022-5222, Class BZ (f)...............................      3.50%       05/25/37           4,867,904
      18,383,170     Series 2022-5223, Class GZ (f)...............................      3.00%       08/25/51          15,826,760
      29,410,013     Series 2022-5224, Class DZ (f)...............................      4.00%       04/25/52          29,033,197
      10,359,375     Series 2022-5225, Class HZ...................................      4.00%       08/25/51          10,576,229
      13,793,189     Series 2022-5225, Class NZ (f)...............................      4.00%       05/25/52          13,788,879
      26,290,356     Series BMOC-2623, Class Z (f) (g)............................      0.00%       10/01/41          19,902,621
       9,012,265     Series BMOC-2655, Class BO (f)...............................      0.00%       05/01/50           4,213,234
      63,538,047     Series SNEX-2019, Class PR1 (f)..............................      2.50%       02/01/42          59,249,229
                  Federal National Mortgage Association
           2,931     Series 1992-38, Class GZ.....................................      7.50%       07/25/22               2,938
             324     Series 1992-185, Class ZB....................................      7.00%       10/25/22                 326
              60     Series 1993-3, Class K.......................................      7.00%       02/25/23                  60
           1,835     Series 1993-39, Class Z......................................      7.50%       04/25/23               1,865
             186     Series 1993-46, Class FH, 7 Yr. Constant Maturity Treasury
                        Rate - 0.20% (a)..........................................      2.22%       04/25/23                 185
          34,873     Series 1993-169, Class L.....................................      6.50%       09/25/23              35,720
          11,164     Series 1993-171, Class SB, 10 Yr. Constant Maturity Treasury
                        Rate (x) -2.17 + 21.99% (c)...............................     16.86%       09/25/23              11,570
           5,437     Series 1993-214, Class 2, IO, STRIPS.........................      7.50%       03/25/23                 121
          75,495     Series 1993-222, Class 2, IO, STRIPS.........................      7.00%       06/25/23               2,177
           5,979     Series 1993-230, Class FA, 1 Mo. LIBOR + 0.60% (a)...........      1.06%       12/25/23               5,997
          48,252     Series 1994-61, Class FG, 1 Mo. LIBOR + 1.50% (a)............      1.96%       04/25/24              48,648
          24,609     Series 1996-51, Class AY, IO.................................      7.00%       12/18/26               2,215
          30,790     Series 1998-37, Class VZ.....................................      6.00%       06/17/28              31,502
         304,064     Series 2000-45, Class SD, IO, 1 Mo. LIBOR (x) -1 +
                        7.95% (c).................................................      7.40%       12/18/30              18,842



                        See Notes to Financial Statements                Page 11





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Federal National Mortgage Association (Continued)
$         37,385     Series 2001-34, Class SR, IO, 1 Mo. LIBOR (x) -1 +
                        8.10% (c).................................................      7.55%       08/18/31    $          2,231
           1,821     Series 2001-42, Class SB, 1 Mo. LIBOR (x) -16 + 128.00%,
                        8.50% Cap (c).............................................      8.50%       09/25/31               1,917
          93,954     Series 2001-46, Class F, 1 Mo. LIBOR + 0.40% (a).............      0.95%       09/18/31              94,193
           6,563     Series 2002-22, Class G......................................      6.50%       04/25/32               7,205
          67,188     Series 2002-30, Class Z......................................      6.00%       05/25/32              72,654
          72,028     Series 2002-80, Class CZ.....................................      4.50%       09/25/32              73,998
          77,898     Series 2002-320, Class 2, IO, STRIPS.........................      7.00%       04/25/32              15,854
          71,056     Series 2002-323, Class 6, IO, STRIPS.........................      6.00%       01/25/32              10,815
         198,866     Series 2002-324, Class 2, IO, STRIPS.........................      6.50%       07/25/32              29,644
          18,207     Series 2003-14, Class AT.....................................      4.00%       03/25/33              18,312
          51,774     Series 2003-21, Class OA.....................................      4.00%       03/25/33              52,443
          75,704     Series 2003-32, Class UI, IO.................................      6.00%       05/25/33              14,052
         343,173     Series 2003-45, Class JB.....................................      5.50%       06/25/33             365,787
       2,154,049     Series 2003-61, Class MZ.....................................      5.00%       08/25/33           2,217,701
          13,724     Series 2003-63, Class F1, 1 Mo. LIBOR + 0.30% (a)............      0.97%       11/25/27              13,740
       1,150,035     Series 2003-63, Class IP, IO.................................      6.00%       07/25/33             187,708
         355,000     Series 2003-71, Class NH.....................................      4.29%       08/25/33             367,861
         160,161     Series 2003-109, Class YB....................................      6.00%       11/25/33             171,396
         223,757     Series 2003-343, Class 2, IO, STRIPS.........................      4.50%       10/25/33              26,927
         212,276     Series 2003-345, Class 14, IO, STRIPS........................      6.00%       03/25/34              35,414
          43,202     Series 2003-348, Class 17, IO, STRIPS........................      7.50%       12/25/33               7,184
          61,803     Series 2003-348, Class 18, IO, STRIPS (d)....................      7.50%       12/25/33              10,891
         196,016     Series 2004-10, Class ZB.....................................      6.00%       02/25/34             210,418
         619,351     Series 2004-18, Class EZ.....................................      6.00%       04/25/34             676,822
         232,069     Series 2004-25, Class LC.....................................      5.50%       04/25/34             249,531
         250,294     Series 2004-25, Class UC.....................................      5.50%       04/25/34             270,532
          42,962     Series 2004-28, Class ZH.....................................      5.50%       05/25/34              47,389
         610,039     Series 2004-60, Class AC.....................................      5.50%       04/25/34             634,669
       1,830,885     Series 2005-2, Class S, IO, 1 Mo. LIBOR (x) -1 + 6.60% (c)...      5.93%       02/25/35             213,886
         304,638     Series 2005-2, Class TB, IO, 1 Mo. LIBOR (x) -1 + 5.90%,
                        0.40% Cap (c).............................................      0.40%       07/25/33               2,732
          58,631     Series 2005-29, Class ZT.....................................      5.00%       04/25/35              61,904
          75,335     Series 2005-40, Class SA, IO, 1 Mo. LIBOR (x) -1 +
                        6.70% (c).................................................      6.03%       05/25/35               9,220
         299,401     Series 2005-52, Class TZ.....................................      6.50%       06/25/35             370,023
       1,083,977     Series 2005-57, Class KZ.....................................      6.00%       07/25/35           1,225,911
           9,081     Series 2005-67, Class SC, 1 Mo. LIBOR (x) -2.15 +
                        14.41% (c)................................................     12.97%       08/25/35               9,712
          40,501     Series 2005-79, Class NS, IO, 1 Mo. LIBOR (x) -1 +
                        6.09% (c).................................................      5.42%       09/25/35               4,559
       4,101,700     Series 2005-86, Class WZ.....................................      5.50%       10/25/35           4,319,383
          13,963     Series 2005-87, Class SC, 1 Mo. LIBOR (x) -1.67 +
                        13.83% (c)................................................     12.72%       10/25/35              16,019
          19,570     Series 2005-90, Class ES, 1 Mo. LIBOR (x) -2.50 +
                        16.88% (c)................................................     15.21%       10/25/35              22,590
          56,376     Series 2005-95, Class WZ.....................................      6.00%       11/25/35              69,344
          21,221     Series 2005-102, Class DS, 1 Mo. LIBOR (x) -2.75 +
                        19.80% (c)................................................     17.96%       11/25/35              21,384
         507,861     Series 2005-104, Class UE....................................      5.50%       12/25/35             541,818
         346,053     Series 2005-359, Class 12, IO, STRIPS........................      5.50%       10/25/35              64,861



Page 12                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Federal National Mortgage Association (Continued)
$        111,354     Series 2005-359, Class 6, IO, STRIPS.........................      5.00%       11/25/35    $         16,543
          98,759     Series 2005-362, Class 13, IO, STRIPS........................      6.00%       08/25/35              18,159
          48,487     Series 2006-5, Class 2A2 (a).................................      1.97%       02/25/35              53,464
      21,891,488     Series 2006-5, Class N2, IO (e)..............................      0.00%       02/25/35                 219
          48,649     Series 2006-15, Class IS, IO, 1 Mo. LIBOR (x) -1 +
                        6.58% (c).................................................      5.91%       03/25/36               7,182
         989,396     Series 2006-20, Class PI, IO, 1 Mo. LIBOR (x) -1 +
                        6.68% (c).................................................      6.01%       11/25/30              51,968
          26,054     Series 2006-31, Class PZ.....................................      6.00%       05/25/36              31,986
          42,572     Series 2006-42, Class CF, 1 Mo. LIBOR + 0.45% (a)............      1.12%       06/25/36              42,612
       1,307,134     Series 2006-42, Class EI, IO, 1 Mo. LIBOR (x) -1 +
                        6.55% (c).................................................      5.88%       06/25/36             187,199
         350,881     Series 2006-59, Class SL, IO, 1 Mo. LIBOR (x) -1 +
                        6.57% (c).................................................      5.90%       07/25/36              49,820
         461,719     Series 2006-80, Class PH.....................................      6.00%       08/25/36             507,223
          57,098     Series 2006-85, Class MZ.....................................      6.50%       09/25/36              62,962
       1,627,826     Series 2006-110, Class PI, IO................................      5.50%       11/25/36             319,155
       1,896,053     Series 2006-116, Class ES, IO, 1 Mo. LIBOR (x) -1 +
                        6.65% (c).................................................      5.98%       12/25/36             259,604
         178,055     Series 2006-117, Class GF, 1 Mo. LIBOR + 0.35% (a)...........      1.02%       12/25/36             177,649
       1,897,887     Series 2006-118, Class A1, 1 Mo. LIBOR + 0.06% (a)...........      0.52%       12/25/36           1,884,772
         313,274     Series 2007-7, Class KA......................................      5.75%       08/25/36             344,847
          20,968     Series 2007-25, Class FB, 1 Mo. LIBOR + 0.33% (a)............      1.00%       04/25/37              20,899
         618,709     Series 2007-28, Class ZA.....................................      6.00%       04/25/37             659,652
         845,079     Series 2007-57, Class ZG.....................................      4.75%       06/25/37             889,786
         549,451     Series 2007-60, Class ZS.....................................      4.75%       07/25/37             602,076
         505,051     Series 2007-68, Class AE.....................................      6.50%       07/25/37             563,331
         319,947     Series 2007-116, Class PB....................................      5.50%       08/25/35             343,453
         104,881     Series 2007-117, Class MD....................................      5.50%       07/25/37             106,852
       3,162,893     Series 2007-W10, Class 3A (e)................................      2.20%       06/25/47           3,286,913
         121,176     Series 2008-3, Class FZ, 1 Mo. LIBOR + 0.55% (a).............      1.22%       02/25/38             122,706
          20,360     Series 2008-8, Class ZA......................................      5.00%       02/25/38              21,288
           9,793     Series 2008-17, Class IP, IO.................................      6.50%       02/25/38                 894
         692,352     Series 2008-389, Class 4, IO, STRIPS.........................      6.00%       03/25/38             121,493
           3,895     Series 2009-10, Class AB.....................................      5.00%       03/25/24               3,930
         702,505     Series 2009-11, Class PI, IO.................................      5.50%       03/25/36             120,903
             907     Series 2009-14, Class BS, IO, 1 Mo. LIBOR (x) -1 +
                        6.25% (c) (h).............................................      5.58%       03/25/24                  17
       1,359,967     Series 2009-37, Class NZ.....................................      5.71%       02/25/37           1,504,118
       4,400,000     Series 2009-50, Class GX.....................................      5.00%       07/25/39           4,710,051
         505,949     Series 2009-64, Class ZD.....................................      8.00%       08/25/39             583,550
       2,938,078     Series 2009-85, Class J......................................      4.50%       10/25/39           3,060,545
         192,869     Series 2009-91, Class HL.....................................      5.00%       11/25/39             191,320
          97,000     Series 2009-92, Class DB.....................................      5.00%       11/25/39             103,560
         801,066     Series 2009-103, Class PZ....................................      6.00%       12/25/39             985,902
         203,621     Series 2009-106, Class SN, IO, 1 Mo. LIBOR (x) -1 +
                        6.25% (c).................................................      5.58%       01/25/40              23,346
         272,220     Series 2009-109, Class PZ....................................      4.50%       01/25/40             278,553
          55,736     Series 2009-115, Class HZ....................................      5.00%       01/25/40              55,288
         982,403     Series 2009-397, Class 2, IO, STRIPS.........................      5.00%       09/25/39             172,198
         136,637     Series 2009-398, Class C13, IO, STRIPS.......................      4.00%       06/25/24               3,573
       1,306,618     Series 2010-2, Class LC......................................      5.00%       02/25/40           1,382,608



                        See Notes to Financial Statements                Page 13





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Federal National Mortgage Association (Continued)
$        195,900     Series 2010-3, Class DZ......................................      4.50%       02/25/40    $        202,153
         151,526     Series 2010-21, Class KO, PO.................................       (b)        03/25/40             133,303
         500,000     Series 2010-35, Class EP.....................................      5.50%       04/25/40             553,419
         345,493     Series 2010-35, Class SJ, 1 Mo. LIBOR (x) -3.33 +
                        17.67% (c)................................................     15.44%       04/25/40             375,190
         327,788     Series 2010-38, Class KC.....................................      4.50%       04/25/40             337,318
         330,713     Series 2010-45, Class WB.....................................      5.00%       05/25/40             346,974
          26,013     Series 2010-49, Class SC, 1 Mo. LIBOR (x) -2 + 12.66% (c)....     11.32%       03/25/40              28,689
         375,244     Series 2010-68, Class BI, IO.................................      5.50%       07/25/50              78,430
          35,555     Series 2010-75, Class MT (e).................................      1.60%       12/25/39              34,657
         136,509     Series 2010-110, Class KI, IO................................      5.50%       10/25/25               2,673
          89,722     Series 2010-115, Class PO, PO................................       (b)        04/25/40              79,608
         253,525     Series 2010-129, Class SM, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.33%       11/25/40              14,273
       2,821,000     Series 2010-142, Class DL....................................      4.00%       12/25/40           2,885,763
       1,682,885     Series 2010-147, Class KS, IO, 1 Mo. LIBOR (x) -1 +
                        5.95% (c).................................................      5.28%       01/25/41              91,991
         164,964     Series 2011-9, Class AZ......................................      5.00%       05/25/40             168,344
       1,507,000     Series 2011-10, Class AY.....................................      6.00%       02/25/41           1,792,300
         118,577     Series 2011-30, Class LS, IO (d).............................      1.56%       04/25/41               6,590
         130,387     Series 2011-30, Class ZB.....................................      5.00%       04/25/41             133,808
         356,425     Series 2011-52, Class GB.....................................      5.00%       06/25/41             375,285
       1,382,021     Series 2011-73, Class PI, IO.................................      4.50%       05/25/41              81,779
         216,148     Series 2011-74, Class TQ, IO, 1 Mo. LIBOR (x) -6.43 +
                        55.93%, 4.50% Cap (c).....................................      4.50%       12/25/33              26,735
       1,318,014     Series 2011-87, Class YI, IO.................................      5.00%       09/25/41             240,672
       2,179,769     Series 2011-101, Class EI, IO................................      3.50%       10/25/26              80,005
         750,000     Series 2011-105, Class MB....................................      4.00%       10/25/41             739,129
       1,756,430     Series 2011-111, Class PZ....................................      4.50%       11/25/41           1,893,735
       4,935,125     Series 2011-123, Class JS, IO, 1 Mo. LIBOR (x) -1 +
                        6.65% (c).................................................      5.98%       03/25/41             424,223
      13,082,500     Series 2011-123, Class ZP....................................      4.50%       12/25/41          13,429,472
       1,546,710     Series 2012-28, Class PT.....................................      4.00%       03/25/42           1,529,885
         776,952     Series 2012-39, Class PB.....................................      4.25%       04/25/42             800,763
         344,382     Series 2012-52, Class BZ.....................................      4.00%       05/25/42             315,322
             660     Series 2012-53, Class CI, IO (h).............................      3.00%       05/25/22                   0
         585,239     Series 2012-65, Class IO, IO.................................      5.50%       07/25/40             101,634
         142,984     Series 2012-66, Class DI, IO.................................      3.50%       06/25/27               7,678
       3,586,711     Series 2012-101, Class AI, IO................................      3.00%       06/25/27             118,015
       3,532,990     Series 2012-103, Class HI, IO................................      3.00%       09/25/27             165,672
         244,772     Series 2012-111, Class B.....................................      7.00%       10/25/42             271,717
         157,063     Series 2012-118, Class IB, IO................................      3.50%       11/25/42              23,279
       8,225,222     Series 2012-122, Class SD, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.43%       11/25/42           1,130,657
         435,138     Series 2012-133, Class KO, PO................................       (b)        12/25/42             227,930
         541,286     Series 2012-138, Class MA....................................      1.00%       12/25/42             480,039
       1,354,855     Series 2012-146, Class QA....................................      1.00%       01/25/43           1,200,535
         308,071     Series 2012-409, Class 49, IO, STRIPS (d)....................      3.50%       11/25/41              46,710
         337,824     Series 2012-409, Class 53, IO, STRIPS (d)....................      3.50%       04/25/42              51,093
         690,000     Series 2013-10, Class HQ.....................................      2.50%       02/25/43             527,347
         414,439     Series 2013-13, Class IK, IO.................................      2.50%       03/25/28              21,147



Page 14                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Federal National Mortgage Association (Continued)
$         58,651     Series 2013-22, Class TS, 1 Mo. LIBOR (x) -1.50 +
                        6.08% (c).................................................      5.39%       03/25/43    $         42,817
          50,011     Series 2013-23, Class ZB.....................................      3.00%       03/25/43              35,122
         750,000     Series 2013-41, Class DB.....................................      3.00%       05/25/43             671,195
       1,228,450     Series 2013-43, Class IX, IO.................................      4.00%       05/25/43             253,229
         406,601     Series 2013-51, Class PI, IO.................................      3.00%       11/25/32              40,426
         406,216     Series 2013-52, Class MD.....................................      1.25%       06/25/43             365,090
       6,433,563     Series 2013-54, Class LI, IO.................................      7.00%       11/25/34           1,214,276
         609,937     Series 2013-55, Class AI, IO.................................      3.00%       06/25/33              66,392
       3,837,241     Series 2013-67, Class IL, IO.................................      6.50%       07/25/43             708,654
         130,300     Series 2013-70, Class JZ.....................................      3.00%       07/25/43             121,783
         108,547     Series 2013-75, Class FC, 1 Mo. LIBOR + 0.25% (a)............      0.92%       07/25/42             108,559
         379,979     Series 2013-105, Class BN....................................      4.00%       05/25/43             372,243
         197,253     Series 2013-105, Class KO, PO................................       (b)        10/25/43             179,156
         195,852     Series 2013-106, Class KN....................................      3.00%       10/25/43             174,537
       1,003,000     Series 2013-130, Class QY....................................      4.50%       06/25/41           1,051,536
       1,926,048     Series 2013-417, Class C21, IO, STRIPS.......................      4.00%       12/25/42             291,275
       4,249,283     Series 2013-418, Class C1, IO, STRIPS........................      3.50%       08/25/43             608,818
          68,955     Series 2014-29, Class GI, IO.................................      3.00%       05/25/29               3,751
       2,791,965     Series 2014-44, Class NI, IO.................................      4.50%       08/25/29             105,355
         145,123     Series 2014-46, Class KA (d).................................     21.26%       08/25/44             251,719
         112,985     Series 2014-68, Class GI, IO.................................      4.50%       10/25/43              11,211
         590,108     Series 2014-82, Class GZ.....................................      4.00%       12/25/44             564,959
         716,057     Series 2014-84, Class LI, IO.................................      3.50%       12/25/26              27,122
         875,000     Series 2015-16, Class MY.....................................      3.50%       04/25/45             843,953
       8,000,000     Series 2015-19, Class JB.....................................      3.50%       04/25/45           7,867,680
          28,166     Series 2015-38, Class GI, IO.................................      3.00%       09/25/43                 343
      10,779,759     Series 2015-40, Class AI, IO.................................      6.00%       05/25/37           2,030,661
         359,818     Series 2015-76, Class BI, IO.................................      4.00%       10/25/39              26,917
          71,287     Series 2015-93, Class KI, IO.................................      3.00%       09/25/44               4,833
       1,234,954     Series 2015-97, Class AI, IO.................................      4.00%       09/25/41              22,110
       4,962,021     Series 2016-2, Class EZ......................................      2.50%       02/25/46           4,652,000
       8,774,460     Series 2016-37, Class PY.....................................      3.00%       06/25/46           8,001,552
      19,039,364     Series 2016-40, Class MS, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.33%       07/25/46           3,304,657
      12,261,682     Series 2016-44, Class Z......................................      3.50%       07/25/46          11,994,197
      11,510,000     Series 2016-50, Class GY.....................................      3.00%       08/25/46          10,514,187
       8,201,660     Series 2016-62, Class SB, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.43%       09/25/46             884,059
         913,100     Series 2016-71, Class NI, IO.................................      3.50%       04/25/46             107,510
       3,181,441     Series 2016-73, Class PI, IO.................................      3.00%       08/25/46             526,903
         409,367     Series 2016-74, Class HI, IO.................................      3.50%       10/25/46              68,081
         338,268     Series 2016-84, Class DF, 1 Mo. LIBOR + 0.42% (a)............      0.65%       11/25/46             337,487
         860,887     Series 2016-87, Class AF, 1 Mo. LIBOR + 0.40% (a)............      0.63%       11/25/46             856,401
       9,380,279     Series 2017-18, Class AS, IO, 1 Mo. LIBOR (x) -1 +
                        6.05% (c).................................................      5.38%       03/25/47           1,596,366
         597,364     Series 2017-46, Class BY.....................................      3.00%       06/25/47             523,783
       9,096,728     Series 2017-49, Class ZJ.....................................      4.00%       07/25/57           9,131,938
      12,080,075     Series 2017-50, Class BZ.....................................      3.00%       07/25/47          11,380,791
       6,427,849     Series 2017-65, Class SA, IO, 1 Mo. LIBOR (x) -1 + 5.90%,
                        5.00% Cap (c).............................................      5.00%       09/25/47             888,340
       3,990,668     Series 2017-84, Class ZK.....................................      3.50%       10/25/57           3,940,481



                        See Notes to Financial Statements                Page 15





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Federal National Mortgage Association (Continued)
$      3,763,262     Series 2017-87, Class GI, IO.................................      4.00%       06/25/44    $        589,066
       2,121,309     Series 2017-87, Class ZA.....................................      4.00%       11/25/57           2,033,984
       2,553,132     Series 2018-17, Class Z......................................      3.50%       03/25/48           2,430,220
      30,505,319     Series 2018-76, Class ZL.....................................      4.00%       10/25/58          30,295,836
       7,050,711     Series 2018-86, Class DL.....................................      3.50%       12/25/48           6,914,620
       3,479,150     Series 2018-92, Class DB.....................................      3.50%       01/25/49           3,402,040
       6,040,730     Series 2018-94, Class AZ.....................................      4.00%       01/25/49           5,890,681
       9,356,169     Series 2019-8, Class DY......................................      3.50%       03/25/49           9,148,345
       8,135,218     Series 2019-17, Class GZ.....................................      4.00%       11/25/56           8,261,325
      11,912,363     Series 2019-26, Class GA.....................................      3.50%       06/25/49          11,769,241
       5,228,355     Series 2019-27, Class HA.....................................      3.00%       06/25/49           5,047,207
       7,852,396     Series 2019-29, Class HT.....................................      3.00%       06/25/49           7,629,145
       6,821,373     Series 2019-34, Class JA.....................................      3.00%       07/25/49           6,643,165
      16,388,357     Series 2019-34, Class LA.....................................      3.00%       07/25/49          15,899,802
       4,608,746     Series 2019-37, Class A......................................      3.00%       07/25/49           4,482,819
      14,654,567     Series 2019-41, Class SN, IO, 1 Mo. LIBOR (x) -1 +
                        6.05% (c).................................................      5.38%       08/25/49           2,257,293
      11,472,115     Series 2019-57, Class JA.....................................      2.50%       10/25/49          10,842,896
       5,178,870     Series 2019-59, Class PT.....................................      2.50%       10/25/49           4,941,259
      12,043,263     Series 2019-66, Class C......................................      3.00%       11/25/49          11,581,944
      40,476,254     Series 2019-68, Class KP.....................................      2.50%       11/25/49          38,156,301
      25,773,960     Series 2019-70, Class WA, PO.................................       (b)        11/25/42          22,072,139
      32,028,020     Series 2020-5, Class BZ......................................      3.00%       02/25/50          30,353,922
      16,435,111     Series 2020-9, Class SJ, IO, 1 Mo. LIBOR (x) -1 + 6.00% (c)..      5.33%       02/25/50           3,172,067
      11,969,763     Series 2020-20, Class KI, IO.................................      4.00%       03/25/50           4,079,372
      35,404,793     Series 2020-34, Class AI, IO.................................      3.50%       06/25/35           3,204,020
      13,423,823     Series 2020-37, Class QI, IO.................................      4.50%       06/25/50           2,620,071
       5,209,044     Series 2020-66, Class IC, IO.................................      6.00%       10/25/47           1,100,528
      45,168,841     Series 2020-74, Class IQ, IO.................................      6.00%       10/25/50           9,185,499
      36,100,411     Series 2020-77, Class DI, IO.................................      4.00%       11/25/35           4,204,539
      15,516,582     Series 2020-93, Class NI, IO.................................      3.00%       01/25/51           1,631,382
      16,543,031     Series 2021-1, Class IB, IO..................................      3.50%       02/25/61           3,480,801
      51,574,507     Series 2021-66, Class CI, IO.................................      4.00%       10/25/36           6,929,633
      10,025,000     Series 2022-15, Class ZH.....................................      3.00%       04/25/52           8,107,815
      53,371,623     Series 2022-18, Class DZ.....................................      3.50%       04/25/52          47,239,821
       8,149,094     Series 2022-18, Class Z......................................      3.50%       04/25/52           7,401,733
                  Federal National Mortgage Association Grantor Trust
       2,088,177     Series 2005-T1, Class A1, 1 Mo. LIBOR + 0.40% (a)............      1.07%       05/25/35           2,091,487
                  Government National Mortgage Association
          21,836     Series 2001-60, Class PZ.....................................      6.00%       12/20/31              21,836
         190,829     Series 2002-72, Class ZB.....................................      6.00%       10/20/32             190,933
         176,124     Series 2003-4, Class MZ......................................      5.50%       01/20/33             180,576
         320,279     Series 2003-18, Class PG.....................................      5.50%       03/20/33             327,494
       1,486,972     Series 2003-35, Class TZ.....................................      5.75%       04/16/33           1,495,424
         125,908     Series 2003-62, Class MZ.....................................      5.50%       07/20/33             134,390
         191,149     Series 2003-84, Class Z......................................      5.50%       10/20/33             199,751
         104,683     Series 2004-37, Class B......................................      6.00%       04/17/34             110,739
         535,487     Series 2004-49, Class MZ.....................................      6.00%       06/20/34             574,584
          43,147     Series 2004-68, Class ZC.....................................      6.00%       08/20/34              46,077
          51,355     Series 2004-71, Class ST, 1 Mo. LIBOR (x) -6.25 + 44.50%,
                        7.00% Cap (c).............................................      7.00%       09/20/34              52,541



Page 16                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Government National Mortgage Association (Continued)
$         92,225     Series 2004-83, Class AK, 1 Mo. LIBOR (x) -3.00 +
                        16.49% (c)................................................     14.71%       10/16/34    $         92,326
         383,862     Series 2004-88, Class SM, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.51%       10/16/34              27,150
          37,428     Series 2004-92, Class AK, 1 Mo. LIBOR (x) -3 + 16.50% (c)....     14.72%       11/16/34              39,468
       1,469,033     Series 2004-92, Class BZ.....................................      5.50%       11/16/34           1,548,300
         237,469     Series 2004-105, Class JZ....................................      5.00%       12/20/34             243,276
         227,624     Series 2004-105, Class KA....................................      5.00%       12/16/34             232,479
         236,483     Series 2005-3, Class JZ......................................      5.00%       01/16/35             232,018
         236,483     Series 2005-3, Class KZ......................................      5.00%       01/16/35             239,337
          18,332     Series 2005-7, Class AJ, 1 Mo. LIBOR (x) -4 + 22.00% (c).....     19.62%       02/16/35              20,587
          13,520     Series 2005-7, Class KA, 1 Mo. LIBOR (x) -2.81 +
                        18.95% (c)................................................     17.28%       12/17/34              13,676
         161,677     Series 2005-7, Class MA, 1 Mo. LIBOR (x) -2.81 +
                        18.95% (c)................................................     17.28%       12/17/34             166,678
         138,113     Series 2005-33, Class AY.....................................      5.50%       04/16/35             143,724
         122,293     Series 2005-41, Class PA.....................................      4.00%       05/20/35             124,282
         278,694     Series 2005-44, Class IO, IO.................................      5.50%       07/20/35              26,961
       2,450,795     Series 2005-78, Class ZA.....................................      5.00%       10/16/35           2,546,398
         212,168     Series 2005-93, Class PO, PO.................................       (b)        06/20/35             194,383
         415,664     Series 2006-17, Class TW.....................................      6.00%       04/20/36             448,698
         500,000     Series 2006-38, Class OH.....................................      6.50%       08/20/36             533,613
         189,913     Series 2006-61, Class ZA.....................................      5.00%       11/20/36             195,551
         447,038     Series 2007-16, Class OZ.....................................      6.00%       04/20/37             485,590
         135,909     Series 2007-27, Class SD, IO, 1 Mo. LIBOR (x) -1 +
                        6.20% (c).................................................      5.61%       05/20/37              10,185
         108,867     Series 2007-41, Class OL, PO.................................       (b)        07/20/37              98,799
         191,800     Series 2007-42, Class SB, IO, 1 Mo. LIBOR (x) -1 +
                        6.75% (c).................................................      6.16%       07/20/37              15,203
          97,637     Series 2007-68, Class NA.....................................      5.00%       11/20/37             100,405
         586,890     Series 2007-71, Class ZD.....................................      6.00%       11/20/37             616,914
         150,377     Series 2007-81, Class FZ, 1 Mo. LIBOR + 0.35% (a)............      0.94%       12/20/37             150,760
          89,665     Series 2008-33, Class XS, IO, 1 Mo. LIBOR (x) -1 +
                        7.70% (c).................................................      7.11%       04/16/38               9,221
         527,619     Series 2008-47, Class ML.....................................      5.25%       06/16/38             553,541
         158,534     Series 2008-54, Class PE.....................................      5.00%       06/20/38             165,865
         419,023     Series 2008-71, Class JI, IO.................................      6.00%       04/20/38              37,141
          20,087     Series 2009-10, Class PA.....................................      4.50%       12/20/38              20,215
         115,041     Series 2009-14, Class KI, IO.................................      6.50%       03/20/39              18,595
          37,748     Series 2009-14, Class KS, IO, 1 Mo. LIBOR (x) -1 +
                        6.30% (c).................................................      5.71%       03/20/39               2,651
          89,930     Series 2009-25, Class SE, IO, 1 Mo. LIBOR (x) -1 +
                        7.60% (c).................................................      7.01%       09/20/38               8,317
       2,747,796     Series 2009-29, Class PC.....................................      7.00%       05/20/39           3,057,091
         406,657     Series 2009-32, Class SZ.....................................      5.50%       05/16/39             437,109
         302,624     Series 2009-42, Class BI, IO.................................      6.00%       06/20/39              36,116
       3,732,479     Series 2009-57, Class VB.....................................      5.00%       06/16/39           3,868,923
         272,974     Series 2009-61, Class PZ.....................................      7.50%       08/20/39             323,431
       9,644,638     Series 2009-61, Class WQ, IO, 1 Mo. LIBOR (x) -1 +
                        6.25% (c).................................................      5.66%       11/16/35           1,123,690
       1,067,115     Series 2009-69, Class ZB.....................................      6.00%       08/20/39           1,099,731



                        See Notes to Financial Statements                Page 17





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Government National Mortgage Association (Continued)
$        743,929     Series 2009-72, Class SM, IO, 1 Mo. LIBOR (x) -1 +
                        6.25% (c).................................................      5.66%       08/16/39    $         75,621
         455,000     Series 2009-75, Class JN.....................................      5.50%       09/16/39             492,511
         610,383     Series 2009-78, Class KZ.....................................      5.50%       09/16/39             680,433
         111,543     Series 2009-79, Class OK, PO.................................       (b)        11/16/37             100,063
         143,619     Series 2009-81, Class TZ.....................................      5.50%       09/20/39             156,764
         689,194     Series 2009-87, Class EI, IO.................................      5.50%       08/20/39              66,744
          69,000     Series 2009-94, Class AL.....................................      5.00%       10/20/39              72,672
         290,553     Series 2009-106, Class DZ....................................      5.50%       11/20/39             321,141
       4,115,244     Series 2009-106, Class SL, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.51%       04/20/36             358,834
          49,414     Series 2009-106, Class WZ....................................      5.50%       11/16/39              54,323
         732,000     Series 2009-126, Class LB....................................      5.00%       12/20/39             781,279
          27,473     Series 2010-4, Class WA......................................      3.00%       01/16/40              27,059
       1,077,374     Series 2010-14, Class BV, IO, 1 Mo. LIBOR (x) -1 +
                        6.25% (c).................................................      5.66%       02/16/40              80,026
         105,788     Series 2010-42, Class CO, PO.................................       (b)        06/16/39             103,516
       1,655,062     Series 2010-46, Class FC, 1 Mo. LIBOR + 0.80% (a)............      1.39%       03/20/35           1,672,865
         909,366     Series 2010-59, Class ZD.....................................      6.50%       05/20/40           1,086,974
       1,247,031     Series 2010-85, Class SL, IO, 1 Mo. LIBOR (x) -1 +
                        6.60% (c).................................................      6.01%       07/20/37              80,758
          87,000     Series 2010-116, Class BM....................................      4.50%       09/16/40              92,136
       1,493,733     Series 2010-116, Class JB....................................      5.00%       06/16/40           1,528,412
         637,326     Series 2010-157, Class OP, PO................................       (b)        12/20/40             556,499
          86,778     Series 2010-166, Class DI, IO................................      4.50%       02/20/39               2,270
         152,511     Series 2011-4, Class PZ......................................      5.00%       01/20/41             162,196
         771,202     Series 2011-35, Class BP.....................................      4.50%       03/16/41             794,656
         230,447     Series 2011-48, Class LI, IO.................................      5.50%       01/16/41              32,164
       6,329,991     Series 2011-61, Class WS, IO, 1 Mo. LIBOR (x) -1 +
                        6.47% (c).................................................      5.88%       02/20/38             573,402
          47,150     Series 2011-63, Class BI, IO.................................      6.00%       02/20/38               3,759
         640,943     Series 2011-71, Class ZC.....................................      5.50%       07/16/34             669,441
       1,598,572     Series 2011-81, Class IC, IO, 1 Mo. LIBOR (x) -1 + 6.72%,
                        0.62% Cap (c).............................................      0.62%       07/20/35              21,351
         385,390     Series 2011-112, Class IP, IO................................      0.50%       08/16/26                  10
         239,265     Series 2011-129, Class CL....................................      5.00%       03/20/41             249,253
           4,418     Series 2011-136, Class GB....................................      2.50%       05/20/40               4,412
         248,473     Series 2011-146, Class EI, IO................................      5.00%       11/16/41              43,241
          39,648     Series 2011-151, Class TB, IO, 1 Mo. LIBOR (x) -70 + 465.50%,
                        3.50% Cap (c).............................................      3.50%       04/20/41               3,323
         305,533     Series 2012-10, Class LI, IO.................................      3.50%       07/20/40               2,929
       2,218,588     Series 2012-18, Class IA, IO, 1 Mo. LIBOR (x) -1 + 6.68%,
                        0.58% Cap (c).............................................      0.58%       07/20/39              20,608
       1,107,688     Series 2012-48, Class MI, IO.................................      5.00%       04/16/42             194,380
       8,496,798     Series 2012-84, Class QS, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.51%       07/16/42             755,020
       6,711,842     Series 2012-84, Class SJ, 1 Mo. LIBOR (x) -0.57 +
                        2.51% (c).................................................      2.17%       07/16/42           4,647,610
         251,623     Series 2012-108, Class KB....................................      2.75%       09/16/42             230,293
       4,324,287     Series 2012-143, Class TI, IO................................      3.00%       12/16/27             227,584
       1,842,856     Series 2012-149, Class PC (d)................................      6.33%       12/20/42           2,003,096
      14,492,819     Series 2013-4, Class IC, IO..................................      4.00%       09/20/42           2,556,955



Page 18                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Government National Mortgage Association (Continued)
$         84,526     Series 2013-5, Class IA, IO..................................      3.50%       10/16/42    $         11,264
         580,008     Series 2013-10, Class DI, IO.................................      3.50%       09/20/42              49,282
       2,223,000     Series 2013-20, Class QM.....................................      2.63%       02/16/43           1,975,556
       1,582,626     Series 2013-22, Class IO, IO.................................      3.00%       02/20/43             197,603
       3,805,063     Series 2013-23, Class IP, IO.................................      3.50%       08/20/42             498,656
       1,764,940     Series 2013-53, Class OI, IO.................................      3.50%       04/20/43             182,959
       1,713,431     Series 2013-69, Class AI, IO.................................      3.50%       05/20/43             267,879
         192,017     Series 2013-69, Class PI, IO.................................      5.00%       05/20/43              20,841
         953,680     Series 2013-70, Class PM.....................................      2.50%       05/20/43             843,966
       2,500,133     Series 2013-91, Class PB.....................................      3.50%       09/20/42           2,486,905
         898,729     Series 2013-130, Class WS, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.51%       09/20/43             154,756
       3,295,552     Series 2013-170, Class IG, IO................................      5.50%       11/16/43             299,749
         688,000     Series 2013-183, Class PB....................................      4.50%       12/20/43             689,541
       2,307,147     Series 2014-6, Class IJ, IO..................................      4.50%       06/16/43             147,456
      13,235,925     Series 2014-30, Class EA (d).................................      1.74%       02/16/44          12,173,509
       5,385,834     Series 2014-43, Class Z......................................      4.00%       03/20/44           5,600,727
       2,592,657     Series 2014-44, Class IC, IO.................................      3.00%       04/20/28             143,360
       6,305,069     Series 2014-44, Class ID, IO (d) (e).........................      0.33%       03/16/44              60,596
          23,142     Series 2014-91, Class JI, IO.................................      4.50%       01/20/40               1,389
         578,935     Series 2014-94, Class Z......................................      4.50%       01/20/44             639,437
       2,901,975     Series 2014-99, Class HI, IO.................................      4.50%       06/20/44             432,373
       3,134,977     Series 2014-115, Class QI, IO................................      3.00%       03/20/29              99,549
       2,959,388     Series 2014-116, Class SB, IO, 1 Mo. LIBOR (x) -1 +
                        5.60% (c).................................................      5.01%       08/20/44             416,340
       1,735,538     Series 2014-118, Class TV, IO, 1 Mo. LIBOR (x) -1 +
                        6.25% (c).................................................      5.66%       05/20/44             203,962
       7,239,944     Series 2015-3, Class ZD......................................      4.00%       01/20/45           7,495,464
      10,074,520     Series 2015-40, Class IO, IO.................................      4.00%       03/20/45           1,686,648
       5,548,729     Series 2015-66, Class LI, IO.................................      5.00%       05/16/45             559,334
          36,607     Series 2015-95, Class IK, IO (d).............................      1.48%       05/16/37                 780
      11,799,061     Series 2015-99, Class EI, IO.................................      5.50%       07/16/45           2,025,446
       6,595,218     Series 2015-124, Class DI, IO................................      3.50%       01/20/38             247,465
         289,341     Series 2015-137, Class WA (d) (e)............................      5.55%       01/20/38             312,337
         416,027     Series 2015-138, Class MI, IO................................      4.50%       08/20/44              46,770
          96,347     Series 2015-151, Class KW (d)................................      5.40%       04/20/34              99,507
       3,691,279     Series 2015-162, Class ZG....................................      4.00%       11/20/45           3,840,950
       4,244,189     Series 2015-168, Class GI, IO................................      5.50%       02/16/33             351,084
         192,471     Series 2016-16, Class KZ.....................................      3.00%       02/16/46             167,374
       7,733,786     Series 2016-37, Class AF, 1 Mo. LIBOR + 0.47% (a)............      0.93%       11/20/43           7,725,106
         159,076     Series 2016-55, Class PB (d).................................      5.63%       03/20/31             164,921
         976,249     Series 2016-69, Class WI, IO.................................      4.50%       05/20/46             236,945
       2,938,126     Series 2016-75, Class SA, IO, 1 Mo. LIBOR (x) -1 +
                        6.00% (c).................................................      5.41%       05/20/40             319,112
         531,265     Series 2016-78, Class UI, IO.................................      4.00%       06/20/46              59,165
       2,823,238     Series 2016-89, Class HI, IO.................................      3.50%       07/20/46             486,909
         334,833     Series 2016-99, Class JA (d).................................      5.51%       11/20/45             358,368
       1,013,003     Series 2016-109, Class ZM....................................      3.50%       08/20/36             964,958
       7,119,273     Series 2016-111, Class PI, IO................................      3.50%       06/20/45             680,938
         743,718     Series 2016-118, Class GI, IO................................      4.50%       02/16/40             105,105
       8,298,402     Series 2016-120, Class AS, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.51%       09/20/46           1,327,348



                        See Notes to Financial Statements                Page 19





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Government National Mortgage Association (Continued)
$        464,000     Series 2016-141, Class PC....................................      5.00%       10/20/46    $        519,581
         324,265     Series 2016-145, Class LZ....................................      3.00%       10/20/46             271,219
         566,450     Series 2016-154, Class WF, 1 Mo. LIBOR + 0.40% (a)...........      0.86%       11/20/45             564,119
       7,332,385     Series 2016-156, Class ZM....................................      3.50%       11/20/46           6,940,687
         303,000     Series 2016-160, Class LE....................................      2.50%       11/20/46             258,525
         217,403     Series 2016-167, Class KI, IO................................      6.00%       12/16/46              32,250
       2,270,481     Series 2017-12, Class SD, IO, 1 Mo. LIBOR (x) -1 +
                        6.10% (c).................................................      5.51%       01/20/47             368,668
         938,842     Series 2017-17, Class KZ.....................................      4.50%       02/20/47           1,017,156
       4,425,567     Series 2017-32, Class DI, IO.................................      5.50%       05/20/35             775,112
       2,610,260     Series 2017-32, Class IB, IO.................................      5.00%       02/16/47             268,745
       6,045,558     Series 2017-33, Class PZ.....................................      3.00%       02/20/47           5,726,160
       4,880,099     Series 2017-56, Class BI, IO.................................      6.00%       04/16/47             804,208
       8,731,357     Series 2017-57, Class IO, IO.................................      5.00%       04/20/47           1,644,721
       3,248,136     Series 2017-113, Class IE, IO................................      5.50%       07/20/47             528,212
       8,422,924     Series 2017-117, Class ZN....................................      3.00%       08/20/47           7,901,374
      12,366,726     Series 2017-122, Class CZ....................................      3.00%       08/20/47          11,508,866
       4,137,004     Series 2017-123, Class IO, IO................................      5.00%       08/16/47             965,321
       5,426,876     Series 2017-130, Class LS, IO, 1 Mo. LIBOR (x) -1 +
                        6.20% (c).................................................      5.61%       08/16/47             602,545
       5,391,389     Series 2017-133, Class JI, IO................................      7.00%       06/20/41             792,952
      11,541,864     Series 2017-134, Class AZ....................................      3.00%       09/20/47          10,774,052
       5,086,282     Series 2017-177, Class DI, IO................................      4.50%       11/16/47             933,670
      14,114,521     Series 2017-179, Class IN, IO................................      5.00%       07/20/44           3,410,406
       3,846,239     Series 2017-186, Class TI, IO, 1 Mo. LIBOR (x) -1 + 6.50%,
                        0.50% Cap (c).............................................      0.50%       05/20/40              47,560
         903,775     Series 2018-44, Class Z......................................      2.50%       09/20/47             746,337
       5,686,862     Series 2018-79, Class IO, IO.................................      5.00%       06/20/48             793,219
      13,057,963     Series 2018-97, Class DZ.....................................      3.50%       07/20/48          12,871,134
       6,623,062     Series 2018-131, Class IA, IO................................      5.00%       04/20/44             758,111
      10,000,000     Series 2018-134, Class KB....................................      3.50%       10/20/48           9,577,457
       8,856,687     Series 2018-155, Class KD....................................      4.00%       11/20/48           8,827,086
       6,682,263     Series 2018-160, Class GY....................................      4.50%       11/20/48           6,672,270
       5,332,621     Series 2018-78I, Class EZ....................................      3.00%       04/20/48           4,988,142
       3,500,893     Series 2019-6, Class EI, IO..................................      5.00%       09/20/39             473,053
       8,788,150     Series 2019-15, Class MZ.....................................      4.50%       02/20/49           8,818,036
      12,488,006     Series 2019-18, Class TP.....................................      3.50%       02/20/49          12,221,845
       1,162,463     Series 2019-27, Class DI, IO.................................      5.50%       01/20/40             184,158
       3,469,097     Series 2019-35, Class BZ.....................................      3.50%       03/20/49           3,475,581
       5,470,267     Series 2019-45, Class ZB.....................................      3.50%       04/20/49           5,417,526
      37,471,898     Series 2019-128, Class EF, 1 Mo. LIBOR + 0.57% (a)...........      1.16%       10/20/49          36,606,529
      20,290,097     Series 2020-31, Class IO, IO.................................      6.50%       03/20/50           2,805,607
      14,385,074     Series 2020-62, Class IA, IO.................................      5.50%       05/20/50           2,809,524
       3,000,000     Series 2020-62, Class IC, IO.................................      2.50%       01/20/50             740,770
      14,014,801     Series 2020-62, Class WI, IO.................................      2.50%       08/20/49           3,266,061
       7,097,422     Series 2020-84, Class IM, IO.................................      2.50%       05/20/50           1,821,387
      19,759,118     Series 2020-84, Class IO, IO.................................      2.50%       04/20/50           5,262,074
      29,612,304     Series 2020-104, Class AI, IO................................      3.00%       07/20/50           4,675,451
      26,069,966     Series 2020-129, Class IO, IO................................      2.50%       09/20/50           3,160,050
      88,501,134     Series 2020-129, Class IU, IO................................      2.50%       09/20/50          10,825,786
      18,414,193     Series 2020-144, Class IK, IO................................      2.50%       09/20/50           2,232,640
      56,175,572     Series 2020-146, Class CI, IO................................      2.50%       10/20/50           7,228,403



Page 20                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Government National Mortgage Association (Continued)
$     42,373,649     Series 2020-162, Class NI, IO................................      2.50%       10/20/50    $      5,255,960
      57,698,586     Series 2020-173, Class MI, IO................................      2.50%       11/20/50           7,617,644
      11,124,722     Series 2020-188, Class IW, IO................................      2.50%       12/20/50           1,545,486
      22,248,342     Series 2020-189, Class IV, IO................................      3.00%       12/20/50           2,868,067
       1,943,845     Series 2021-7, Class KI, IO..................................      2.50%       01/20/51             259,408
      20,618,165     Series 2021-8, Class DI, IO..................................      3.50%       01/20/51           2,388,309
      16,524,662     Series 2021-15, Class JI, IO.................................      2.50%       01/20/51           1,844,088
     105,277,138     Series 2021-24, Class XI, IO.................................      2.00%       02/20/51          11,765,762
      50,612,181     Series 2021-27, Class IO, IO.................................      2.50%       02/20/51           6,841,623
      39,017,404     Series 2021-27, Class PI, IO.................................      2.00%       02/20/51           3,819,897
      35,121,331     Series 2021-32, Class AI, IO.................................      2.00%       02/20/51           3,894,316
       7,485,831     Series 2021-46, Class IL, IO.................................      3.00%       03/20/51           1,073,386
      12,696,965     Series 2021-46, Class LI, IO.................................      3.00%       03/20/51           1,674,194
      10,317,535     Series 2021-69, Class IX, IO.................................      3.00%       04/20/51           1,571,581
      26,107,627     Series 2021-91, Class IB, IO.................................      3.00%       05/20/51           3,427,610
     104,150,857     Series 2021-97, Class NI, IO.................................      2.50%       08/20/49          10,400,192
      33,910,141     Series 2021-159, Class QE....................................      2.00%       09/20/51          31,001,851
      40,930,000     Series 2021-188, Class PA....................................      2.00%       10/20/51          37,725,651
      17,014,000     Series 2022-46, Class LY.....................................      3.00%       03/20/52          15,478,287
       5,537,209     Series 2022-60, Class CZ.....................................      3.00%       03/20/52           4,409,909
      31,879,216     Series 2022-63, Class AZ (f).................................      3.00%       08/20/51          29,687,520
      16,305,930     Series 2022-63, Class BZ (f).................................      3.50%       11/20/46          16,280,452
      19,165,098     Series 2022-63, Class HZ (f).................................      2.50%       11/20/51          15,913,020
      10,927,213     Series 2022-63, Class MZ (f).................................      3.00%       05/20/51          10,194,748
       6,982,427     Series 2022-68, Class DZ (f).................................      3.50%       04/20/52           6,461,472
      12,170,000     Series 2022-68, Class MZ (f).................................      3.50%       04/20/52          12,280,291
      50,000,000     Series 2022-68, Class XA (f).................................      3.50%       02/20/49          49,908,203
      12,563,000     Series 2022-68, Class Z (f)..................................      3.50%       04/20/52          11,954,480
      16,891,166     Series 2022-68, Class ZC (f).................................      3.50%       04/20/52          16,785,596
      12,991,946     Series 2022-69, Class QL.....................................      3.00%       04/20/52          12,409,741
      10,917,513     Series 2022-78, Class AM (f).................................      3.50%       04/20/52          10,211,286
      20,000,000     Series BMOC-2631, Class Z (a) (f) (g)........................      0.00%       09/01/57          13,840,625
                  Seasoned Credit Risk Transfer Trust
      15,000,000     Series 2022-1, Class MBU.....................................      3.25%       11/25/61          13,709,337
                  Seasoned Loans Structured Transaction Trust
       4,352,120     Series 2019-3, Class A1C.....................................      2.75%       11/25/29           4,240,062
                  Vendee Mortgage Trust
       1,819,382     Series 2003-2, Class Z.......................................      5.00%       05/15/33           1,880,421
       6,422,691     Series 2010-1, Class DZ......................................      4.25%       04/15/40           6,406,586
      10,030,323     Series 2011-1, Class DZ......................................      3.75%       09/15/46           9,608,267
      20,313,753     Series 2011-2, Class DZ......................................      3.75%       10/15/41          19,741,470
                                                                                                                ----------------
                                                                                                                   1,705,956,351
                                                                                                                ----------------
                  COMMERCIAL MORTGAGE-BACKED SECURITIES -- 11.7%
                  Federal Home Loan Mortgage Corporation Multiclass Certificates
      50,000,000     Series 2020-RR06, Class BX, IO (d)...........................      1.84%       05/27/33           7,136,007
      37,600,000     Series 2020-RR09, Class AX, IO (d) (f) (i)...................      2.63%       11/27/28           5,457,866
      47,500,000     Series 2020-RR09, Class BX, IO (d) (f) (i)...................      2.20%       02/27/29           6,085,938
      96,907,000     Series 2020-RR10, Class X, IO (d)............................      2.01%       12/27/27           8,440,105
     112,919,000     Series 2020-RR11, Class AX, IO (d)...........................      2.84%       01/27/29          16,302,658
      44,200,500     Series 2020-RR11, Class BX, IO (d)...........................      2.44%       12/27/28           4,697,302
      39,569,234     Series 2021-P009, Class X, IO (e)............................      1.56%       01/25/31           2,816,059



                        See Notes to Financial Statements                Page 21





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COMMERCIAL MORTGAGE-BACKED SECURITIES (CONTINUED)
                  Federal Home Loan Mortgage Corporation Multiclass Certificates
                   (Continued)
$      4,377,911     Series 2021-P011, Class X1, IO (e)...........................      1.84%       09/25/45    $        620,783
     112,345,000     Series 2021-RR15, Class X, IO (e)............................      1.56%       10/27/34          14,762,167
     100,924,000     Series 2021-RR18, Class X, IO (e) (f) (i)....................      1.90%       10/27/28           9,781,756
      55,000,000     Series 2021-RR20, Class X, IO (e)............................      1.85%       04/25/33           8,631,007
                  Federal Home Loan Mortgage Corporation Multifamily Structured
                   Pass Through Certificates
     114,005,843     Series 2013-K030, Class X1, IO (e)...........................      0.26%       04/25/23             151,958
      75,206,460     Series 2014-K036, Class X1, IO (e)...........................      0.84%       10/25/23             675,602
      42,758,691     Series 2015-K721, Class X1, IO (e)...........................      0.45%       08/25/22              34,233
     290,132,823     Series 2016-KIR1, Class X, IO (e)............................      1.19%       03/25/26          10,176,467
      12,000,000     Series 2018-K156, Class A3...................................      3.70%       06/25/33          12,103,700
      28,941,200     Series 2018-K157, Class A2...................................      3.99%       05/25/33          30,023,873
       7,101,000     Series 2018-K159, Class A3...................................      3.95%       11/25/33           7,258,355
      57,765,039     Series 2019-K099, Class X1, IO (e)...........................      1.00%       09/25/29           3,136,491
      57,790,000     Series 2019-K099, Class XAM, IO (e)..........................      1.26%       09/25/29           4,262,301
      69,644,531     Series 2019-K101, Class X1, IO (d)...........................      0.95%       10/25/29           3,612,963
      64,993,000     Series 2019-K102, Class XAM, IO (d)..........................      1.21%       10/25/29           4,600,529
      59,029,000     Series 2019-K103, Class XAM, IO (e)..........................      1.01%       11/25/29           3,543,806
     103,328,139     Series 2019-K734, Class X1, IO (e)...........................      0.78%       02/25/26           2,114,404
      68,018,000     Series 2019-K734, Class XAM, IO (e)..........................      0.55%       02/25/26           1,113,115
      42,398,402     Series 2019-K735, Class X1, IO (e)...........................      1.09%       05/25/26           1,387,594
      57,404,996     Series 2019-K736, Class X1, IO (e)...........................      1.43%       07/25/26           2,464,058
      28,620,944     Series 2019-K1510, Class X1, IO (e)..........................      0.64%       01/25/34           1,227,163
     158,343,252     Series 2019-K1512, Class X1, IO (e)..........................      1.05%       04/25/34          12,084,709
      56,995,381     Series 2019-K1513, Class X1, IO (e)..........................      0.99%       08/25/34           4,233,241
      18,674,000     Series 2020-K109, Class XAM, IO (e)..........................      1.91%       04/25/30           2,263,216
     108,672,016     Series 2020-K110, Class X1, IO (e)...........................      1.81%       04/25/30          11,550,890
      29,090,000     Series 2020-K112, Class XAM, IO (e)..........................      1.77%       05/25/30           3,303,492
      82,019,000     Series 2020-K113, Class XAM, IO (e)..........................      1.69%       06/25/30           8,935,880
      53,100,000     Series 2020-K114, Class XAM, IO (e)..........................      1.44%       06/25/30           4,877,421
      50,703,859     Series 2020-K115, Class X1, IO (e)...........................      1.43%       06/25/30           4,425,433
      55,537,412     Series 2020-K115, Class XAM, IO (e)..........................      1.65%       07/25/30           5,921,815
      16,455,041     Series 2020-K116, Class X1, IO (e)...........................      1.53%       07/25/30           1,516,872
      55,500,000     Series 2020-K116, Class XAM, IO (e)..........................      1.70%       08/25/30           6,195,587
      63,500,000     Series 2020-K117, Class XAM, IO (e)..........................      1.53%       09/25/30           6,355,683
      34,886,485     Series 2020-K118, Class X1, IO (e)...........................      1.05%       09/25/30           2,261,126
      37,051,661     Series 2020-K118, Class XAM, IO (e)..........................      1.26%       09/25/30           3,082,961
      51,000,000     Series 2020-K119, Class XAM, IO (e)..........................      1.23%       10/25/30           4,123,574
      75,535,017     Series 2020-K120, Class XAM, IO (e)..........................      1.31%       10/25/30           6,537,767
      21,236,000     Series 2020-K121, Class XAM, IO (e)..........................      1.29%       11/25/30           1,829,847
      29,940,542     Series 2020-K122, Class X1, IO (e)...........................      0.97%       11/25/30           1,796,908
      35,210,000     Series 2020-K122, Class XAM, IO (e)..........................      1.17%       11/25/30           2,754,292
      75,577,469     Series 2020-K737, Class X1, IO (d)...........................      0.75%       10/25/26           1,753,102
      38,559,000     Series 2020-K738, Class XAM, IO (d)..........................      1.48%       03/25/27           2,287,802
     131,750,487     Series 2020-K739, Class X1, IO (e)...........................      1.32%       09/25/27           6,830,419
      40,072,531     Series 2020-K739, Class XAM, IO (e)..........................      1.67%       09/25/27           2,930,765
      33,000,000     Series 2020-K740, Class XAM (e)..............................      1.20%       10/25/27           1,762,735
      90,051,216     Series 2020-K1515, Class X1, IO (e)..........................      1.64%       02/25/35          12,147,099
      86,959,598     Series 2020-K1516, Class X1, IO (e)..........................      1.63%       05/25/35          12,693,032
      94,352,088     Series 2020-K1517, Class X1, IO (e)..........................      1.44%       07/25/35          12,130,291
      52,941,375     Series 2020-KG04, Class X1, IO (e)...........................      0.94%       11/25/30           3,072,950



Page 22                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COMMERCIAL MORTGAGE-BACKED SECURITIES (CONTINUED)
                  Federal Home Loan Mortgage Corporation Multifamily Structured
                   Pass Through Certificates (Continued)
$     49,625,000     Series 2021-K123, Class XAM, IO (a)..........................      1.07%       12/25/30    $      3,544,461
      26,688,000     Series 2021-K124, Class XAM, IO (e)..........................      1.03%       01/25/31           1,827,898
      41,267,000     Series 2021-K125, Class XAM, IO (e)..........................      0.87%       01/25/31           2,406,246
      33,900,000     Series 2021-K128, Class XAM, IO (e)..........................      0.83%       03/25/31           1,881,257
      27,836,000     Series 2021-K129, Class XAM, IO (a)..........................      1.33%       05/25/31           2,542,220
      41,565,013     Series 2021-K130, Class XAM, IO (e)..........................      1.32%       07/25/31           3,899,530
      44,491,000     Series 2021-K132, Class XAM, IO (e)..........................      0.96%       09/25/31           2,989,773
     107,703,000     Series 2021-K741, Class XAM, IO (e)..........................      1.03%       12/25/27           5,175,668
     107,126,540     Series 2021-K744, Class X1, IO (e)...........................      0.96%       07/25/28           4,869,051
     149,814,120     Series 2021-K1520, Class X1, IO (e)..........................      0.58%       02/25/36           6,976,289
     142,000,000     Series 2021-KG05, Class X1, IO (e)...........................      0.40%       01/25/31           3,343,433
      64,485,402     Series 2021-KG06, Class X1, IO (e)...........................      0.63%       10/25/31           2,639,691
      13,000,000     Series 2021-KI08, Class A, 30 Day Average SOFR +
                        0.20% (a).................................................      0.36%       10/25/26          12,981,192
                  FREMF Mortgage Trust
       5,000,000     Series 2013-K24, Class B (e) (j).............................      3.63%       11/25/45           5,018,142
       9,850,000     Series 2013-K26, Class B (e) (j).............................      3.72%       12/25/45           9,900,223
       6,203,000     Series 2013-K28, Class B (e) (j).............................      3.61%       06/25/46           6,215,715
       8,700,000     Series 2013-K29, Class B (e) (j).............................      3.59%       05/25/46           8,713,589
      11,943,000     Series 2013-K32, Class B (e) (j).............................      3.64%       10/25/46          11,935,973
      23,320,000     Series 2013-K35, Class B (e) (j).............................      4.07%       12/25/46          23,509,233
       5,710,000     Series 2015-K720, Class B (e) (j)............................      3.54%       07/25/22           5,716,176
       8,401,000     Series 2015-K720, Class C (e) (j)............................      3.54%       07/25/22           8,406,110
      16,266,829     Series 2015-K721, Class B (e) (j)............................      3.71%       11/25/47          16,313,741
                  Government National Mortgage Association
       3,526,862     Series 2011-31, Class Z (d)..................................      3.58%       09/16/52           3,364,796
      18,656,237     Series 2012-120, Class Z (d).................................      2.46%       01/16/55          15,661,002
         100,000     Series 2013-74, Class AG (e).................................      2.60%       12/16/53              89,237
           6,959     Series 2013-194, Class AE (d)................................      2.75%       11/16/44               6,785
      16,056,385     Series 2015-30, Class DZ.....................................      2.95%       05/16/55          14,844,537
      27,885,020     Series 2015-30, Class IO, IO (d).............................      0.68%       07/16/56             878,866
       7,720,866     Series 2015-70, Class IO, IO (d).............................      0.61%       12/16/49             178,652
       4,609,972     Series 2015-125, Class VA (d)................................      2.70%       05/16/35           4,423,249
      18,226,797     Series 2016-2, Class IO, IO (d)..............................      0.56%       04/16/57             467,840
      16,671,861     Series 2016-11, Class IO, IO (d).............................      0.84%       01/16/56             669,814
       9,278,969     Series 2016-26, Class IO, IO (d).............................      0.69%       02/16/58             290,311
      25,403,119     Series 2016-34, Class IO, IO (d).............................      0.92%       01/16/58           1,112,321
      10,865,473     Series 2016-36, Class IO, IO (d).............................      0.73%       08/16/57             374,710
      12,920,320     Series 2016-52, Class IO, IO (d).............................      0.75%       03/16/58             483,984
       4,021,015     Series 2016-110, Class VA....................................      2.10%       01/16/38           3,628,582
      19,079,517     Series 2016-113, Class IO, IO (d)............................      1.08%       02/16/58           1,050,955
      10,972,209     Series 2016-127, Class IO, IO (d)............................      0.86%       05/16/58             511,735
      33,896,377     Series 2016-166, Class IO, IO (d)............................      0.92%       04/16/58           1,629,934
       3,145,979     Series 2017-23, Class Z......................................      2.50%       05/16/59           2,589,725
       4,093,376     Series 2017-35, Class Z (d)..................................      2.50%       05/16/59           3,421,654
       7,020,000     Series 2017-76, Class B......................................      2.60%       12/16/56           6,237,429
       3,234,287     Series 2017-106, Class AE....................................      2.60%       12/16/56           3,006,866
       2,599,995     Series 2017-146, Class Z.....................................      2.60%       09/16/57           2,203,141
       4,280,169     Series 2018-4, Class Z.......................................      2.50%       10/16/59           3,503,317
      13,696,340     Series 2018-98, Class C (d)..................................      3.00%       08/16/60          11,987,053
      17,117,421     Series 2018-123, Class Z.....................................      2.50%       06/16/60          14,166,292



                        See Notes to Financial Statements                Page 23





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COMMERCIAL MORTGAGE-BACKED SECURITIES (CONTINUED)
                  Government National Mortgage Association (Continued)
$     24,481,854     Series 2018-170, Class Z.....................................      2.50%       11/16/60    $     21,749,941
      18,087,544     Series 2019-7, Class Z.......................................      2.50%       01/16/61          15,209,389
       1,856,688     Series 2019-104, Class Z.....................................      2.80%       05/16/61           1,538,081
      10,200,000     Series 2020-143, Class B.....................................      2.00%       03/16/62           7,980,240
       6,700,000     Series 2020-161, Class B.....................................      2.00%       08/16/62           5,180,943
       8,720,766     Series 2020-169, Class Z.....................................      1.83%       06/16/62           5,372,907
      22,373,468     Series 2022-43, Class Z......................................      2.00%       09/16/61          16,881,697
                                                                                                                ----------------
                                                                                                                     643,778,765
                                                                                                                ----------------
                  PASS-THROUGH SECURITIES -- 43.0%
                  Federal Home Loan Mortgage Corporation
       1,230,480     Pool 760043, 5 Yr. Constant Maturity Treasury Rate +
                        1.39% (a).................................................      2.98%       12/01/48           1,248,744
       4,606,710     Pool 840359, 12 Mo. LIBOR + 1.64% (a)........................      1.93%       06/01/46           4,728,209
          92,342     Pool A19763..................................................      5.00%       04/01/34              96,989
         389,945     Pool A47828..................................................      3.50%       08/01/35             382,646
         179,324     Pool A47937..................................................      5.50%       08/01/35             191,087
          62,658     Pool A48972..................................................      5.50%       05/01/36              66,658
          70,195     Pool A54675..................................................      5.50%       01/01/36              75,664
         148,098     Pool A65324..................................................      5.50%       09/01/37             156,164
          87,821     Pool A97294..................................................      4.00%       02/01/41              89,043
         711,425     Pool B70791..................................................      4.00%       06/01/39             725,112
           3,337     Pool C01310..................................................      6.50%       03/01/32               3,630
          11,276     Pool C03458..................................................      5.00%       02/01/40              11,974
          40,783     Pool C03949..................................................      3.50%       05/01/42              40,410
          97,257     Pool C04269..................................................      3.00%       10/01/42              93,984
         157,449     Pool C91167..................................................      5.00%       04/01/28             163,317
         113,166     Pool C91353..................................................      3.50%       01/01/31             110,202
          16,826     Pool C91482..................................................      3.50%       07/01/32              16,797
          14,223     Pool E02883..................................................      4.00%       04/01/26              14,532
          15,671     Pool G01443..................................................      6.50%       08/01/32              16,829
         255,239     Pool G02017..................................................      5.00%       12/01/35             272,574
         252,820     Pool G04593..................................................      5.50%       01/01/37             269,378
         114,789     Pool G04814..................................................      5.50%       10/01/38             122,318
          22,069     Pool G05173..................................................      4.50%       11/01/31              22,797
         233,115     Pool G05275..................................................      5.50%       02/01/39             249,407
          64,519     Pool G05449..................................................      4.50%       05/01/39              67,423
         191,951     Pool G06583..................................................      5.00%       06/01/41             205,347
         470,998     Pool G07100..................................................      5.50%       07/01/40             502,693
          44,772     Pool G07266..................................................      4.00%       12/01/42              45,171
         335,978     Pool G07329..................................................      4.00%       01/01/43             340,651
         351,416     Pool G07683..................................................      4.00%       03/01/44             356,312
           1,818     Pool G08113..................................................      6.50%       02/01/36               1,967
         955,641     Pool G08854..................................................      5.00%       12/01/48             998,766
           2,766     Pool G12959..................................................      6.50%       10/01/22               2,781
             119     Pool G12978..................................................      5.50%       12/01/22                 120
           7,993     Pool G13625..................................................      5.50%       01/01/24               8,103
          32,638     Pool G13733..................................................      5.00%       11/01/24              33,393
          29,749     Pool G14088..................................................      4.00%       02/01/26              30,345
          27,304     Pool G14106..................................................      6.00%       10/01/24              27,527
           8,098     Pool G14167..................................................      5.50%       07/01/23               8,190
           1,671     Pool G14233..................................................      6.00%       01/01/24               1,679



Page 24                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  PASS-THROUGH SECURITIES (CONTINUED)
                  Federal Home Loan Mortgage Corporation (Continued)
$        325,888     Pool G14348..................................................      4.00%       10/01/26    $        331,980
          10,837     Pool G14376..................................................      4.00%       09/01/25              11,035
          19,842     Pool G14995..................................................      5.50%       12/01/24              20,054
           1,171     Pool G15821..................................................      5.00%       07/01/25               1,195
          72,904     Pool G15949..................................................      4.00%       01/01/29              74,266
          11,200     Pool G15957..................................................      5.50%       12/01/24              11,264
          56,998     Pool G18264..................................................      5.00%       07/01/23              58,153
          85,998     Pool G18287..................................................      5.50%       12/01/23              87,501
          10,044     Pool G60020..................................................      4.50%       12/01/43              10,350
         407,689     Pool G60114..................................................      5.50%       06/01/41             434,341
         620,563     Pool G60168..................................................      4.50%       07/01/45             646,286
         218,038     Pool G60194..................................................      3.50%       08/01/45             215,863
         227,007     Pool G60808..................................................      3.00%       10/01/46             218,258
       2,133,751     Pool G60921..................................................      4.50%       02/01/47           2,210,397
       8,324,232     Pool G60940..................................................      4.00%       09/01/46           8,469,962
       2,832,390     Pool G61160..................................................      4.50%       11/01/45           2,959,058
           5,228     Pool H09034..................................................      5.50%       05/01/37               5,476
           2,385     Pool J05364..................................................      6.00%       08/01/22               2,393
          60,093     Pool J09465..................................................      4.00%       04/01/24              61,182
          35,085     Pool J09504..................................................      4.00%       04/01/24              35,722
           9,387     Pool J09798..................................................      4.00%       05/01/24               9,561
          15,782     Pool J10623..................................................      4.00%       09/01/24              16,069
         170,903     Pool N70075..................................................      5.00%       01/01/35             173,669
         286,669     Pool N70081..................................................      5.50%       07/01/38             295,328
          57,572     Pool Q07189..................................................      4.00%       04/01/42              58,374
          19,332     Pool Q07479..................................................      3.50%       04/01/42              19,155
          83,474     Pool Q11791..................................................      3.50%       10/01/42              82,708
          57,303     Pool Q11836..................................................      3.50%       10/01/42              56,777
         407,690     Pool Q14034..................................................      3.50%       12/01/42             405,672
       1,750,268     Pool Q50564..................................................      4.50%       09/01/47           1,793,243
       6,602,997     Pool Q53219..................................................      4.50%       12/01/47           6,910,093
         465,665     Pool Q54651..................................................      4.50%       03/01/48             484,513
         768,302     Pool Q55037..................................................      4.50%       04/01/48             800,664
       5,336,616     Pool Q55152..................................................      4.50%       04/01/48           5,523,523
       2,293,471     Pool Q56260..................................................      5.00%       05/01/48           2,448,377
       2,932,919     Pool Q58363..................................................      5.00%       09/01/48           3,054,747
       1,457,195     Pool Q58483..................................................      4.50%       09/01/48           1,488,591
       2,007,725     Pool Q61217..................................................      4.00%       01/01/49           2,027,248
       3,434,196     Pool QA4774..................................................      4.00%       11/01/49           3,482,848
       2,601,542     Pool QB4340..................................................      3.00%       10/01/50           2,465,443
      14,701,818     Pool QD5978..................................................      3.00%       02/01/52          13,919,855
      10,284,129     Pool QD5999..................................................      3.00%       02/01/52           9,735,645
      11,961,441     Pool QE0773..................................................      4.00%       04/01/52          12,099,835
      14,008,724     Pool QE1612..................................................      4.00%       05/01/52          14,248,763
       8,477,414     Pool QK1195..................................................      2.50%       11/01/41           7,899,951
      13,814,136     Pool QK1203..................................................      2.50%       11/01/41          12,864,924
       3,478,494     Pool QN2804..................................................      1.50%       07/01/35           3,190,803
         324,290     Pool QN3055..................................................      1.50%       08/01/35             297,489
       5,788,213     Pool RA3086..................................................      2.50%       07/01/50           5,304,007
          41,201     Pool SC0036..................................................      3.00%       06/01/38              39,721
      34,913,389     Pool SD0859..................................................      3.50%       05/01/50          34,101,364
      24,051,677     Pool SD0927..................................................      3.50%       04/01/52          23,684,468



                        See Notes to Financial Statements                Page 25





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  PASS-THROUGH SECURITIES (CONTINUED)
                  Federal Home Loan Mortgage Corporation (Continued)
$     24,807,973     Pool SD0959..................................................      3.50%       04/01/52    $     24,331,015
       8,236,445     Pool SD8031..................................................      3.50%       12/01/49           8,035,348
               1     Pool SD8044..................................................      3.00%       02/01/50                   1
       2,379,306     Pool SD8045..................................................      3.50%       02/01/50           2,324,223
       6,293,097     Pool SD8062..................................................      3.00%       05/01/50           5,972,907
         339,440     Pool U50165..................................................      4.00%       05/01/32             342,581
       2,242,086     Pool U59020..................................................      4.00%       06/01/35           2,262,565
       1,345,599     Pool U64762..................................................      4.50%       10/01/45           1,400,121
       5,679,587     Pool U69020..................................................      5.00%       07/01/44           6,037,937
       3,598,552     Pool U69041..................................................      5.00%       11/01/43           3,834,994
          98,883     Pool U80068..................................................      3.50%       10/01/32              97,368
          65,304     Pool U80212..................................................      3.50%       02/01/33              64,360
          83,095     Pool U90245..................................................      3.50%       10/01/42              82,523
         845,770     Pool U90690..................................................      3.50%       06/01/42             839,938
          12,149     Pool U90932..................................................      3.00%       02/01/43              11,666
          34,147     Pool U92272..................................................      4.50%       12/01/43              35,762
          99,518     Pool U99045..................................................      3.50%       03/01/43              98,829
         108,635     Pool U99084..................................................      4.50%       02/01/44             114,157
          49,377     Pool U99091..................................................      4.50%       03/01/44              51,385
         147,587     Pool U99096..................................................      4.50%       05/01/44             154,570
       1,461,275     Pool ZS2492..................................................      6.50%       04/01/35           1,602,691
                  Federal National Mortgage Association
          42,454     Pool 190371..................................................      6.50%       07/01/36              46,084
          25,164     Pool 255190..................................................      5.50%       05/01/34              26,802
          12,419     Pool 255984..................................................      4.50%       11/01/25              12,656
          77,610     Pool 256181..................................................      5.50%       03/01/36              80,909
         294,779     Pool 256576..................................................      5.50%       01/01/37             310,129
           6,744     Pool 256808..................................................      5.50%       07/01/37               6,819
          49,497     Pool 256936..................................................      6.00%       10/01/37              51,729
          52,225     Pool 545759..................................................      6.50%       07/01/32              56,518
          11,889     Pool 555851..................................................      6.50%       01/01/33              12,709
         190,504     Pool 683246..................................................      5.50%       02/01/33             202,506
         160,585     Pool 725014..................................................      5.50%       12/01/33             171,578
         348,473     Pool 735415..................................................      6.50%       12/01/32             375,335
           3,116     Pool 745875..................................................      6.50%       09/01/36               3,360
          40,973     Pool 747097..................................................      6.00%       10/01/29              42,452
         308,630     Pool 788149..................................................      5.50%       05/01/33             332,048
         145,793     Pool 812741..................................................      5.50%       02/01/35             152,405
         172,141     Pool 827948..................................................      5.50%       05/01/35             179,975
         262,039     Pool 850000..................................................      5.50%       01/01/36             282,188
          35,300     Pool 871039..................................................      5.50%       02/01/37              36,155
         917,282     Pool 879015..................................................      4.00%       10/01/35             930,547
         111,689     Pool 888001..................................................      5.50%       10/01/36             120,420
          95,952     Pool 888163..................................................      7.00%       12/01/33             105,207
              82     Pool 888435..................................................      5.50%       06/01/22                  82
         316,806     Pool 889610..................................................      5.50%       06/01/38             337,440
          10,800     Pool 890149..................................................      6.50%       10/01/38              11,879
          16,683     Pool 890231..................................................      5.00%       07/01/25              17,027
           3,250     Pool 890314..................................................      5.50%       12/01/22               3,264
           3,174     Pool 890378..................................................      6.00%       05/01/24               3,220
         777,306     Pool 890556..................................................      4.50%       10/01/43             807,022
         647,642     Pool 890736..................................................      5.00%       07/01/30             677,635



Page 26                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  PASS-THROUGH SECURITIES (CONTINUED)
                  Federal National Mortgage Association (Continued)
$        139,478     Pool 905917..................................................      5.50%       01/01/37    $        149,911
          66,960     Pool 922386..................................................      5.50%       01/01/37              66,972
          11,008     Pool 930562..................................................      5.00%       02/01/39              11,770
          82,511     Pool 931808..................................................      5.50%       08/01/39              87,901
         129,907     Pool 953115..................................................      5.50%       11/01/38             135,845
          19,596     Pool 962556..................................................      5.00%       04/01/23              19,965
           7,971     Pool 973561..................................................      5.00%       03/01/23               8,119
          42,822     Pool 976871..................................................      6.50%       08/01/36              46,095
          14,418     Pool 995097..................................................      6.50%       10/01/37              15,863
          78,869     Pool 995149..................................................      6.50%       10/01/38              85,965
          37,154     Pool 995228..................................................      6.50%       11/01/38              41,081
          24,027     Pool 995252..................................................      5.00%       12/01/23              24,494
          12,020     Pool 995259..................................................      6.50%       11/01/23              12,175
          97,616     Pool AA3303..................................................      5.50%       06/01/38             100,902
         448,039     Pool AB0460..................................................      5.50%       02/01/37             471,966
         150,041     Pool AB0731..................................................      4.00%       06/01/39             153,329
          37,931     Pool AB2092..................................................      4.00%       01/01/41              38,438
          16,179     Pool AB2133..................................................      4.00%       01/01/26              16,468
         869,686     Pool AB2506..................................................      5.00%       03/01/41             930,800
       1,043,725     Pool AB2959..................................................      4.50%       07/01/40           1,051,061
          74,733     Pool AB5174..................................................      3.50%       05/01/42              73,986
          91,670     Pool AB5919..................................................      3.00%       08/01/42              88,513
         188,832     Pool AB6671..................................................      3.00%       10/01/42             182,330
         244,259     Pool AB7765..................................................      3.00%       02/01/43             235,845
         152,912     Pool AB7859..................................................      3.50%       02/01/43             151,380
         438,677     Pool AB8676..................................................      3.50%       05/01/42             419,380
         630,457     Pool AB9551..................................................      3.00%       06/01/43             608,296
          18,955     Pool AC1232..................................................      5.00%       07/01/24              19,337
         177,143     Pool AC3267..................................................      5.50%       09/01/39             190,087
          44,458     Pool AD0889..................................................      6.00%       09/01/24              45,127
         286,357     Pool AD4317..................................................      4.00%       04/01/40             288,967
           8,926     Pool AD5222..................................................      4.50%       05/01/30               9,097
          58,572     Pool AD7137..................................................      5.50%       07/01/40              62,932
         187,842     Pool AE0137..................................................      4.50%       03/01/36             196,030
          63,300     Pool AE4476..................................................      4.00%       03/01/41              64,122
          83,305     Pool AE7005..................................................      4.00%       10/01/40              84,261
       3,040,342     Pool AE7733..................................................      5.00%       11/01/40           3,241,440
          21,083     Pool AE9284..................................................      4.00%       11/01/40              21,358
         493,380     Pool AE9959..................................................      5.00%       03/01/41             520,273
         242,305     Pool AH0979..................................................      3.50%       01/01/41             235,453
         161,378     Pool AH1089..................................................      4.00%       11/01/40             162,725
          89,682     Pool AH1141..................................................      4.50%       12/01/40              93,629
          61,705     Pool AH4404..................................................      4.00%       01/01/41              62,512
          56,226     Pool AH7204..................................................      4.00%       03/01/41              56,963
         144,421     Pool AI6093..................................................      4.50%       06/01/31             147,438
          55,008     Pool AI6503..................................................      5.00%       11/01/39              57,083
          22,823     Pool AI6581..................................................      4.50%       07/01/41              23,833
         103,831     Pool AI8779..................................................      4.00%       11/01/41             105,186
         330,091     Pool AI9114..................................................      4.00%       06/01/42             337,057
       1,712,401     Pool AI9124..................................................      4.00%       08/01/42           1,748,537
         942,881     Pool AI9158..................................................      6.50%       01/01/41           1,062,637
         644,264     Pool AK0765..................................................      4.00%       03/01/42             660,830



                        See Notes to Financial Statements                Page 27





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  PASS-THROUGH SECURITIES (CONTINUED)
                  Federal National Mortgage Association (Continued)
$        120,751     Pool AK4520..................................................      4.00%       03/01/42    $        122,138
         112,438     Pool AK5555..................................................      4.00%       04/01/42             113,903
          71,860     Pool AL0212..................................................      5.50%       02/01/38              76,517
         179,928     Pool AL0241..................................................      4.00%       04/01/41             182,282
           3,749     Pool AL0399..................................................      6.00%       08/01/24               3,792
           1,694     Pool AL0446..................................................      6.00%       05/01/24               1,710
           4,839     Pool AL1195..................................................      6.00%       09/01/23               4,901
         389,323     Pool AL1850..................................................      5.50%       07/01/40             414,573
          69,399     Pool AL2142..................................................      6.50%       09/01/38              75,374
         336,096     Pool AL2551..................................................      3.50%       10/01/42             332,735
           8,032     Pool AL2589..................................................      5.50%       05/01/25               8,103
          68,006     Pool AL2892..................................................      3.50%       12/01/42              67,331
         445,976     Pool AL3093..................................................      3.50%       02/01/43             441,528
          18,108     Pool AL3154..................................................      3.00%       02/01/43              17,484
       1,023,269     Pool AL4703..................................................      3.50%       12/01/28           1,017,059
           5,168     Pool AL4962..................................................      6.00%       05/01/24               5,234
          96,906     Pool AL5616..................................................      5.50%       09/01/41             103,195
         519,627     Pool AL5890..................................................      4.50%       03/01/43             543,813
           1,449     Pool AL6057..................................................      6.00%       08/01/24               1,458
       1,950,755     Pool AL6513..................................................      5.00%       07/01/44           2,063,678
          56,134     Pool AL6948..................................................      5.00%       09/01/25              57,259
          67,470     Pool AL7046..................................................      3.50%       06/01/45              66,750
         188,978     Pool AL7231..................................................      3.50%       08/01/45             186,925
         414,109     Pool AL7449..................................................      8.50%       12/01/37             468,415
         518,832     Pool AL7637..................................................      5.00%       01/01/42             530,325
       1,800,129     Pool AL7905..................................................      4.50%       03/01/34           1,869,882
          76,770     Pool AL8139..................................................      4.00%       02/01/32              76,599
          58,767     Pool AL8353..................................................      3.50%       08/01/44              58,180
       2,719,524     Pool AL8652..................................................      5.00%       07/01/44           2,959,459
         341,696     Pool AL9143..................................................      3.50%       09/01/36             340,071
         115,841     Pool AL9226..................................................      5.50%       12/01/41             126,006
         866,052     Pool AL9777..................................................      4.50%       01/01/47             899,638
         189,303     Pool AP1197..................................................      3.50%       09/01/42             187,878
         115,180     Pool AP7963..................................................      4.00%       09/01/42             117,074
       1,591,639     Pool AQ0411..................................................      3.50%       10/01/42           1,575,839
         683,215     Pool AQ0535..................................................      3.00%       11/01/42             658,343
         428,914     Pool AQ1534..................................................      3.50%       10/01/32             421,939
         361,661     Pool AQ1607..................................................      3.50%       11/01/32             355,735
          44,703     Pool AQ9715..................................................      3.00%       01/01/43              43,098
         260,737     Pool AQ9999..................................................      3.00%       02/01/43             251,505
         958,997     Pool AR7582..................................................      3.50%       03/01/33             943,540
         185,126     Pool AR7961..................................................      3.50%       03/01/33             182,148
       2,523,182     Pool AS1719..................................................      5.00%       02/01/44           2,698,034
         324,246     Pool AS5236..................................................      4.00%       05/01/45             323,510
         565,488     Pool AS5515..................................................      3.50%       06/01/30             570,263
         230,087     Pool AS5635..................................................      3.00%       08/01/45             221,026
         191,560     Pool AS7211..................................................      3.00%       04/01/46             182,055
       4,591,239     Pool AS8548..................................................      3.50%       12/01/46           4,561,172
         214,827     Pool AS9990..................................................      4.50%       07/01/47             219,660
          69,125     Pool AT0332..................................................      3.00%       04/01/43              64,973
         536,852     Pool AT1747..................................................      3.00%       04/01/43             518,185
         310,815     Pool AT3892..................................................      3.00%       06/01/43             294,592



Page 28                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  PASS-THROUGH SECURITIES (CONTINUED)
                  Federal National Mortgage Association (Continued)
$        194,975     Pool AT4180..................................................      3.50%       05/01/33    $        191,919
          64,290     Pool AY0013..................................................      4.50%       01/01/45              65,531
         407,974     Pool BA4113..................................................      3.00%       04/01/46             389,666
       7,006,901     Pool BD6438..................................................      3.00%       10/01/46           6,730,789
         276,591     Pool BE3631..................................................      4.50%       05/01/47             284,745
       1,621,311     Pool BH2633..................................................      5.00%       08/01/47           1,703,207
          16,129     Pool BH9428..................................................      4.50%       09/01/47              16,578
       9,881,221     Pool BJ1637..................................................      3.50%       11/01/47           9,716,066
          82,595     Pool BJ6232..................................................      5.00%       04/01/48              85,771
         765,637     Pool BJ9100..................................................      4.50%       02/01/48             802,685
         456,907     Pool BJ9111..................................................      4.50%       03/01/48             473,207
       1,163,120     Pool BJ9124..................................................      4.50%       04/01/48           1,220,248
         263,724     Pool BK4769..................................................      5.00%       08/01/48             275,104
          79,715     Pool BK4851..................................................      5.00%       05/01/48              82,621
       3,549,725     Pool BK8883..................................................      5.00%       09/01/48           3,810,274
       1,396,092     Pool BK9563..................................................      4.50%       12/01/48           1,434,108
       3,423,841     Pool BK9599..................................................      5.00%       08/01/48           3,575,037
      12,535,730     Pool BM4122..................................................      7.47%       01/01/40          13,919,914
       4,370,770     Pool BM4561..................................................      5.00%       09/01/48           4,622,115
       5,678,331     Pool BM4785..................................................      4.50%       10/01/38           6,000,826
       5,933,513     Pool BM5671..................................................      4.50%       01/01/49           6,216,680
       5,706,536     Pool BM6018..................................................      5.00%       05/01/49           5,735,069
         900,642     Pool BM6602..................................................      3.50%       02/01/48             867,191
         421,686     Pool BN1027..................................................      5.50%       03/01/49             444,442
      17,515,849     Pool BN3925..................................................      4.50%       01/01/49          18,252,176
       1,130,973     Pool BN4059..................................................      4.00%       12/01/48           1,126,302
       3,207,632     Pool BN4328..................................................      5.00%       01/01/49           3,394,375
       5,681,984     Pool BO5426..................................................      4.00%       10/01/49           5,779,096
       7,261,603     Pool BP1649..................................................      3.50%       02/01/50           7,078,283
       3,199,821     Pool BP4238..................................................      3.00%       04/01/50           3,036,404
         656,857     Pool BP6504..................................................      1.50%       07/01/35             602,543
       1,770,431     Pool BP8797..................................................      3.00%       07/01/50           1,688,641
       4,984,902     Pool BQ3099..................................................      3.00%       10/01/50           4,741,349
      10,689,022     Pool BT9396..................................................      2.50%       11/01/41           9,954,508
       6,825,332     Pool BT9397..................................................      2.50%       11/01/41           6,360,378
      10,753,570     Pool BU8953..................................................      4.00%       04/01/52          10,861,256
       6,491,259     Pool CA1576..................................................      5.00%       01/01/48           6,796,707
       3,756,956     Pool CA1917..................................................      5.00%       06/01/48           3,979,991
       2,104,583     Pool CA2520..................................................      4.00%       10/01/33           2,165,281
       3,826,982     Pool CA2947..................................................      4.00%       12/01/48           3,907,706
       9,320,296     Pool CA4978..................................................      3.00%       01/01/50           8,845,535
       7,341,578     Pool CA5352..................................................      3.50%       03/01/50           7,157,172
      27,643,844     Pool CA5569..................................................      4.00%       04/01/50          27,945,159
      10,449,189     Pool CA6423..................................................      3.00%       07/01/50           9,910,161
      50,168,483     Pool CB3507..................................................      4.00%       04/01/52          50,704,355
       1,998,696     Pool FM1284..................................................      3.50%       02/01/46           1,978,791
       1,824,947     Pool FM1285..................................................      4.00%       10/01/43           1,848,678
       1,879,456     Pool FM1287..................................................      5.00%       11/01/44           1,973,949
      40,937,979     Pool FM1725..................................................      2.50%       11/01/47          37,765,132
      20,527,367     Pool FM1873..................................................      3.00%       11/01/49          19,468,101
       8,734,357     Pool FM2001..................................................      5.00%       09/01/49           9,138,566
       5,608,830     Pool FM2450..................................................      3.50%       12/01/39           5,705,273



                        See Notes to Financial Statements                Page 29





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  PASS-THROUGH SECURITIES (CONTINUED)
                  Federal National Mortgage Association (Continued)
$     50,455,005     Pool FM3047..................................................      4.00%       04/01/45    $     51,565,255
      17,347,923     Pool FM3053..................................................      3.50%       04/01/50          16,928,428
      15,554,663     Pool FM3431..................................................      3.00%       05/01/50          14,787,341
       9,597,770     Pool FM4681..................................................      2.50%       11/01/50           8,819,781
      13,831,487     Pool FM7685..................................................      3.00%       06/01/51          13,108,667
       7,404,093     Pool FM8218..................................................      4.00%       04/01/48           7,520,769
      35,440,970     Pool FM8927..................................................      4.00%       10/01/49          36,290,279
      12,819,084     Pool FM8953..................................................      5.00%       11/01/43          13,659,682
      19,632,897     Pool FM9224..................................................      4.00%       10/01/51          19,686,003
      43,952,157     Pool FM9263..................................................      2.00%       10/01/41          40,005,495
       5,577,964     Pool FM9408..................................................      4.50%       06/01/46           5,774,934
      11,515,797     Pool FS0032..................................................      3.00%       12/01/51          10,999,529
      54,288,945     Pool FS0697..................................................      2.50%       02/01/42          50,828,599
      19,307,553     Pool FS1021..................................................      3.00%       02/01/52          18,415,011
      17,547,409     Pool FS1029..................................................      3.00%       02/01/52          16,760,734
      28,175,698     Pool FS1143..................................................      3.00%       03/01/52          26,892,899
      36,317,832     Pool FS1267..................................................      4.00%       04/01/52          36,715,648
      49,989,360     Pool FS1268..................................................      4.00%       04/01/52          50,664,031
      30,000,000     Pool FS1501..................................................      4.00%       08/01/51          29,970,092
      61,921,998     Pool FS1524..................................................      2.50%       04/01/42          57,512,004
      13,777,294     Pool FS1525..................................................      3.00%       04/01/52          13,159,624
      16,683,039     Pool FS1540..................................................      3.00%       04/01/42          16,150,100
      30,148,500     Pool FS1541..................................................      3.00%       04/01/42          29,109,349
      27,169,608     Pool FS1573..................................................      2.50%       11/01/41          25,268,308
      11,187,050     Pool FS1639..................................................      4.00%       04/01/52          11,332,495
      25,000,000     Pool FS1640..................................................      4.00%       04/01/52          25,207,085
      26,848,196     Pool FS1666..................................................      3.50%       05/01/52          26,430,314
      25,616,779     Pool FS1670..................................................      4.00%       04/01/52          25,914,524
      25,000,000     Pool FS1671..................................................      4.00%       05/01/52          25,272,613
      25,000,000     Pool FS1672..................................................      4.00%       05/01/52          25,194,722
          86,006     Pool MA0096..................................................      4.50%       06/01/29              87,653
           2,051     Pool MA0293..................................................      4.50%       01/01/30               2,090
          33,413     Pool MA0295..................................................      5.00%       01/01/30              34,963
          29,132     Pool MA0353..................................................      4.50%       03/01/30              29,690
         770,410     Pool MA0443..................................................      5.00%       05/01/30             806,248
          17,699     Pool MA0444..................................................      5.00%       06/01/40              18,696
         204,440     Pool MA0575..................................................      4.50%       11/01/30             208,770
         104,586     Pool MA0633..................................................      5.00%       01/01/41             109,539
           3,651     Pool MA0777..................................................      5.00%       06/01/31               3,820
          30,559     Pool MA1222..................................................      4.00%       10/01/32              31,004
          52,092     Pool MA1228..................................................      3.00%       09/01/42              50,224
         296,419     Pool MA1373..................................................      3.50%       03/01/43             294,123
         153,764     Pool MA2024..................................................      4.00%       07/01/29             157,734
         652,831     Pool MA2099..................................................      3.50%       11/01/29             658,398
         278,607     Pool MA2454..................................................      3.50%       09/01/30             280,758
           2,129     Pool MA2509..................................................      3.00%       01/01/46               1,999
       1,295,839     Pool MA2916..................................................      4.00%       02/01/47           1,328,976
         187,514     Pool MA3101..................................................      4.50%       08/01/47             192,906
         125,113     Pool MA3123..................................................      5.00%       08/01/47             131,178
         250,037     Pool MA3205..................................................      5.00%       10/01/47             262,181
      11,311,804     Pool MA3774..................................................      3.00%       09/01/49          10,723,349
       2,701,676     Pool MA3835..................................................      3.50%       11/01/49           2,635,994



Page 30                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  PASS-THROUGH SECURITIES (CONTINUED)
                  Federal National Mortgage Association (Continued)
$      1,890,444     Pool MA3991..................................................      3.00%       04/01/50    $      1,793,235
         942,045     Pool MA4122..................................................      1.50%       09/01/35             864,178
         797,128     Pool MA4154..................................................      1.50%       10/01/35             731,233
      10,000,000     Pool TBA.....................................................      2.50%       05/15/52           9,133,594
      68,000,000     Pool TBA.....................................................      3.00%       05/15/52          64,198,906
      60,000,000     Pool TBA.....................................................      2.50%       06/15/52          54,688,753
      85,000,000     Pool TBA (k).................................................      1.50%       06/15/52          71,642,928
      10,000,000     Pool TBA.....................................................      2.00%       06/15/52           8,817,642
     277,000,000     Pool TBA (k).................................................      4.00%       06/15/52         274,949,549
     230,000,000     Pool TBA (k).................................................      4.50%       06/15/52         232,987,454
     150,000,000     Pool TBA (k).................................................      4.00%       07/15/52         148,532,226
                  Government National Mortgage Association
          60,652     Pool 3149....................................................      6.00%       10/20/31              64,939
          39,017     Pool 3172....................................................      6.00%       12/20/31              42,796
          40,747     Pool 3227....................................................      6.00%       04/20/32              43,505
           8,175     Pool 3474....................................................      6.00%       11/20/33               8,824
          83,523     Pool 4251....................................................      5.50%       10/20/23              84,706
          56,985     Pool 455986..................................................      5.25%       07/15/25              56,004
          81,585     Pool 487108..................................................      6.00%       04/15/29              87,426
          33,791     Pool 553144..................................................      5.50%       04/15/33              36,339
             134     Pool 589331..................................................      6.00%       10/15/22                 134
         105,312     Pool 604338..................................................      5.00%       05/15/33             112,055
          93,900     Pool 604897..................................................      5.00%       12/15/33              99,816
         106,882     Pool 605389..................................................      5.00%       04/15/34             113,747
         243,532     Pool 615403..................................................      4.50%       08/15/33             257,039
           8,929     Pool 627123..................................................      5.50%       03/15/34               9,660
          70,941     Pool 638704..................................................      5.50%       11/15/36              75,803
         154,998     Pool 653143..................................................      4.90%       04/15/36             162,562
         244,772     Pool 658324..................................................      5.50%       03/15/37             258,604
         123,415     Pool 677190..................................................      5.00%       06/15/38             131,353
          16,449     Pool 687833..................................................      6.00%       08/15/38              18,112
          41,868     Pool 706840..................................................      4.50%       05/15/40              44,547
         190,797     Pool 706855..................................................      4.50%       09/15/40             203,002
         249,645     Pool 711483..................................................      4.00%       01/15/40             259,456
         113,323     Pool 711543..................................................      4.00%       11/15/40             117,791
         742,307     Pool 711563..................................................      4.50%       03/15/41             789,832
       4,806,030     Pool 720225..................................................      4.50%       07/15/39           5,076,055
         249,424     Pool 723216..................................................      4.50%       08/15/40             262,972
          66,068     Pool 723248..................................................      5.00%       10/15/39              70,302
         250,681     Pool 724230..................................................      5.00%       08/15/39             266,115
          64,958     Pool 724267..................................................      5.00%       09/15/39              68,995
         169,636     Pool 724340..................................................      4.50%       09/15/39             177,617
          81,422     Pool 725272..................................................      4.50%       11/15/39              84,259
          42,542     Pool 726394..................................................      4.50%       10/15/39              44,919
          19,193     Pool 728921..................................................      4.50%       12/15/24              19,479
         205,519     Pool 733595..................................................      4.50%       04/15/40             226,440
          78,291     Pool 733733..................................................      5.00%       06/15/40              82,975
         505,088     Pool 736317..................................................      4.25%       06/20/36             518,143
         103,570     Pool 736617..................................................      4.00%       12/15/35             106,609
         772,712     Pool 737673..................................................      4.50%       11/15/40             814,449
         181,907     Pool 737996..................................................      4.00%       02/15/41             188,241
         244,428     Pool 739341..................................................      3.50%       10/15/41             245,860



                        See Notes to Financial Statements                Page 31





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  PASS-THROUGH SECURITIES (CONTINUED)
                  Government National Mortgage Association (Continued)
$        153,787     Pool 743673..................................................      4.50%       07/15/40    $        164,581
         257,367     Pool 745478..................................................      5.00%       08/20/40             273,440
         570,997     Pool 748939..................................................      4.00%       09/20/40             580,275
          78,635     Pool 754384..................................................      4.50%       03/20/42              83,702
         286,854     Pool 762905..................................................      4.50%       04/15/41             301,628
       1,208,467     Pool 769102..................................................      4.50%       07/20/41           1,230,968
         311,448     Pool 781623..................................................      5.00%       06/15/33             326,612
          49,309     Pool 781697..................................................      6.00%       11/15/33              54,322
         253,213     Pool 781824..................................................      5.50%       11/15/34             276,609
           9,980     Pool 781862..................................................      5.50%       01/15/35              10,947
          32,991     Pool 782070..................................................      7.00%       06/15/32              35,072
         105,189     Pool 782259..................................................      5.00%       02/15/36             109,831
          53,109     Pool 782810..................................................      4.50%       11/15/39              56,821
          81,303     Pool 783091..................................................      5.50%       06/15/40              89,540
          17,858     Pool 783220..................................................      5.50%       09/15/24              18,239
         129,776     Pool 783375..................................................      5.00%       08/15/41             137,567
       8,076,463     Pool 783590..................................................      4.50%       06/20/41           8,491,971
         204,962     Pool 783760..................................................      5.00%       02/15/42             218,291
       2,883,569     Pool 784063..................................................      5.00%       09/20/45           3,044,234
         456,829     Pool 784343..................................................      5.00%       02/15/41             487,429
       3,802,451     Pool 784752..................................................      4.00%       03/15/45           3,952,374
       2,214,984     Pool 785020..................................................      3.00%       05/20/50           2,097,308
       2,008,284     Pool AC0197..................................................      4.00%       12/20/42           2,063,102
         408,119     Pool AD0026..................................................      3.50%       06/20/33             406,017
          84,940     Pool AD0856..................................................      3.75%       08/20/33              85,845
          36,361     Pool AG8899..................................................      4.00%       12/20/43              37,095
         671,225     Pool AI6317..................................................      4.50%       06/20/44             690,899
         408,966     Pool AK2389..................................................      4.50%       11/20/44             419,967
         112,128     Pool AN4469..................................................      5.00%       12/15/40             117,114
         234,294     Pool AR8421..................................................      5.00%       10/20/41             243,536
         990,953     Pool BB1216..................................................      4.50%       06/20/47           1,051,293
         430,239     Pool BB4731..................................................      4.00%       07/20/47             435,081
         303,582     Pool BB4757..................................................      4.00%       08/20/47             307,276
         166,853     Pool BB4769..................................................      4.00%       08/20/47             167,785
         433,437     Pool BD0483..................................................      4.50%       11/20/47             454,663
         454,791     Pool BF0415..................................................      5.00%       06/20/35             473,755
         275,026     Pool BL6909..................................................      5.00%       03/20/49             285,096
       5,431,638     Pool BU8989..................................................      5.50%       06/20/40           5,846,384
         860,701     Pool BX7975..................................................      5.50%       09/20/39             926,614
       1,451,224     Pool CB3161..................................................      5.50%       03/20/50           1,549,807
       1,459,195     Pool CB8275..................................................      5.50%       09/20/39           1,555,611
       2,503,665     Pool CC3552..................................................      5.50%       08/20/40           2,696,103
       1,956,352     Pool CC3563..................................................      5.50%       09/20/35           2,106,380
       1,916,847     Pool CC3564..................................................      6.00%       09/20/39           2,071,170
         927,609     Pool CC3565..................................................      6.50%       01/20/39           1,047,857
       4,859,479     Pool CC3583..................................................      5.50%       09/20/35           5,241,947
       2,206,665     Pool CC8859..................................................      5.50%       10/20/35           2,375,154
       4,519,074     Pool CC8868..................................................      5.50%       06/20/40           4,848,649
       3,787,405     Pool CD4286..................................................      6.00%       11/20/39           4,110,190
         761,469     Pool CD6819..................................................      6.50%       01/20/39             820,714
       1,648,844     Pool CE1292..................................................      6.00%       01/20/39           1,788,468
         860,270     Pool CE1819..................................................      5.50%       12/20/39             925,946



Page 32                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES (CONTINUED)
                  PASS-THROUGH SECURITIES (CONTINUED)
                  Government National Mortgage Association (Continued)
$      3,029,157     Pool CE6488..................................................      6.00%       09/20/39    $      3,284,895
       1,734,834     Pool CE6489..................................................      6.50%       12/20/38           1,889,022
       5,028,901     Pool CE6491..................................................      6.00%       07/20/36           5,454,234
         733,192     Pool CE6626..................................................      6.00%       12/20/38             795,097
       1,740,675     Pool CE7158..................................................      5.50%       05/20/40           1,867,618
       1,249,748     Pool CE9078..................................................      5.50%       01/20/39           1,324,487
         142,674     Pool MA1017..................................................      6.00%       05/20/43             155,366
         100,713     Pool MA1162..................................................      6.00%       07/20/43             109,735
          12,185     Pool MA2215..................................................      3.50%       09/20/44              11,887
          92,904     Pool MA2683..................................................      6.00%       03/20/45             101,166
          91,580     Pool MA2759..................................................      6.00%       01/20/45              99,726
          40,353     Pool MA2897..................................................      6.00%       03/20/45              43,948
         180,731     Pool MA2966..................................................      6.00%       09/20/39             196,924
         200,994     Pool MA3249..................................................      6.00%       04/20/40             219,002
         405,306     Pool MA3459..................................................      6.00%       08/20/39             441,629
         411,630     Pool MA4076..................................................      7.00%       01/20/39             449,850
       2,888,152     Pool MA5714..................................................      6.00%       01/20/49           3,085,685
                                                                                                                ----------------
                                                                                                                   2,377,307,787
                                                                                                                ----------------
                  TOTAL U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES.....................................     4,727,042,903
                  (Cost $4,939,301,031)                                                                         ----------------

MORTGAGE-BACKED SECURITIES -- 13.3%

                  COLLATERALIZED MORTGAGE OBLIGATIONS -- 8.4%
                  Angel Oak Mortgage Trust
       6,603,373     Series 2021-4, Class A1 (j)..................................      1.04%       01/20/65           6,216,142
       7,782,224     Series 2021-5, Class A1 (j)..................................      0.95%       07/25/66           7,041,630
                  Arroyo Mortgage Trust
       9,000,000     Series 2019-2, Class M1 (j)..................................      4.76%       04/25/49           8,619,339
       3,464,718     Series 2019-3, Class A3 (j)..................................      3.42%       10/25/48           3,384,274
       3,251,575     Series 2021-1R, Class A2 (j).................................      1.48%       10/25/48           3,055,443
       4,489,125     Series 2021-1R, Class A3 (j).................................      1.64%       10/25/48           4,222,302
                  Barclays Mortgage Loan Trust
       6,446,064     Series 2021-NQM1, Class A1 (j)...............................      1.75%       09/25/51           6,090,410
                  BRAVO Residential Funding Trust
       2,299,175     Series 2021-NQM1, Class A2 (j)...............................      1.26%       02/25/49           2,185,830
       5,747,937     Series 2021-NQM1, Class A3 (j)...............................      1.33%       02/25/49           5,462,382
       4,555,466     Series 2021-NQM2, Class A1 (j)...............................      0.97%       03/25/60           4,418,905
                  CFMT LLC
       4,052,000     Series 2021-EBO1, Class M1 (j)...............................      1.65%       11/25/50           3,892,399
                  Chase Home Lending Mortgage Trust
       3,194,730     Series 2019-1, Class A11, 1 Mo. LIBOR + 0.85% (a) (j)........      1.52%       03/25/50           3,179,036
         248,457     Series 2019-ATR2, Class A11, 1 Mo. LIBOR +
                        0.90% (a) (j).............................................      1.57%       07/25/49             246,699
                  CHL Mortgage Pass-Through Trust
          30,253     Series 2004-8, Class 2A1.....................................      4.50%       06/25/19              30,328
                  CIM Trust
       1,137,257     Series 2017-7, Class A (j)...................................      3.00%       04/25/57           1,140,444
       2,292,360     Series 2018-J1, Class A22 (j)................................      3.50%       03/25/48           2,206,847
       1,996,899     Series 2019-INV1, Class A11 (j)..............................      4.00%       02/25/49           1,991,455
       3,763,716     Series 2019-INV3, Class A11, 1 Mo. LIBOR +
                        1.00% (a) (j).............................................      1.41%       08/25/49           3,757,468



                        See Notes to Financial Statements                Page 33





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  Citigroup Global Markets Mortgage Securities VII, Inc.
$            241     Series 2003-UP2, Class PO1, PO...............................       (b)        12/25/18    $            214
                  Connecticut Avenue Securities Trust
       3,252,753     Series 2019-R01, Class 2M2, 1 Mo. LIBOR + 2.45% (a) (j)......      3.12%       07/25/31           3,264,371
       1,525,852     Series 2019-R02, Class 1M2, 1 Mo. LIBOR + 2.30% (a) (j)......      2.97%       08/25/31           1,526,917
         483,775     Series 2019-R03, Class 1M2, 1 Mo. LIBOR + 2.15% (a) (j)......      2.82%       09/25/31             483,934
       2,564,447     Series 2019-R06, Class 2M2, 1 Mo. LIBOR + 2.10% (a) (j)......      2.77%       09/25/39           2,565,081
       2,950,000     Series 2022-R02, Class 2M2, 30 Day Average SOFR +
                        3.00% (a) (j).............................................      3.29%       01/25/42           2,911,735
       6,000,000     Series 2022-R03, Class 1M2, 30 Day Average SOFR +
                        3.50% (a) (j).............................................      3.79%       03/25/42           6,114,805
       4,251,000     Series 2022-R04, Class 1M2, 30 Day Average SOFR +
                        3.10% (a) (j).............................................      3.39%       03/25/42           4,278,648
                  Ellington Financial Mortgage Trust
       6,248,000     Series 2022-2, Class A1 (j)..................................      4.30%       04/25/67           6,191,597
                  Federal Home Loan Mortgage Corporation STACR Debt Notes
      14,432,499     Series 2020-HQA5, Class M2, 30 Day Average SOFR +
                        2.60% (a) (j).............................................      2.89%       11/25/50          14,479,411
       5,500,000     Series 2022-DNA2, Class M1B, 30 Day Average SOFR +
                        2.40% (a) (j).............................................      2.69%       02/25/42           5,408,518
                  Federal Home Loan Mortgage Corporation STACR REMIC Trust
       1,697,988     Series 2020-DNA1, Class M2, 1 Mo. LIBOR +
                        1.70% (a) (j).............................................      2.37%       01/25/50           1,692,443
       1,623,624     Series 2020-HQA2, Class M2, 1 Mo. LIBOR +
                        3.10% (a) (j).............................................      3.77%       03/25/50           1,631,514
       6,250,000     Series 2021-DNA5, Class M2, 30 Day Average SOFR +
                        1.65% (a) (j).............................................      1.94%       01/25/34           6,203,737
       4,000,000     Series 2022-DNA3, Class M1B, 30 Day Average SOFR +
                        2.90% (a) (j).............................................      3.15%       04/25/42           4,008,340
                  Federal Home Loan Mortgage Corporation STACR Trust
      11,439,641     Series 2018-DNA2, Class M2, 1 Mo. LIBOR +
                        2.15% (a) (j).............................................      2.82%       12/25/30          11,537,022
       5,936,144     Series 2019-HQA1, Class M2, 1 Mo. LIBOR +
                        2.35% (a) (j).............................................      3.02%       02/25/49           5,981,623
       5,694,137     Series 2019-HQA2, Class M2, 1 Mo. LIBOR +
                        2.05% (a) (j).............................................      2.72%       04/25/49           5,720,711
       4,326,280     Series 2019-HQA3, Class M2, 1 Mo. LIBOR +
                        1.85% (a) (j).............................................      2.52%       09/25/49           4,319,206
                  Federal National Mortgage Association Connecticut Avenue
                   Securities
      12,540,232     Series 2018-C03, Class 1M2, 1 Mo. LIBOR + 2.15% (a)..........      2.82%       10/25/30          12,650,541
      11,505,153     Series 2018-C06, Class 1M2, 1 Mo. LIBOR + 2.00% (a)..........      2.67%       03/25/31          11,522,581
                  Flagstar Mortgage Trust
         532,959     Series 2018-2, Class A4 (j)..................................      3.50%       04/25/48             531,653
       2,482,614     Series 2018-4, Class B1 (e) (j)..............................      4.25%       07/25/48           2,419,011
       1,796,205     Series 2019-2, Class A11 (j).................................      3.50%       12/25/49           1,733,324
       3,236,725     Series 2020-1INV, Class A11, 1 Mo. LIBOR + 0.85% (a) (j).....      1.52%       03/25/50           3,209,012
      18,345,064     Series 2021-9INV, Class A1 (j)...............................      2.50%       09/25/41          17,211,598
                  GMACM Mortgage Loan Trust
             892     Series 2003-J10, Class A1....................................      4.75%       01/25/19                 874
                  GS Mortgage-Backed Securities Corp. Trust
         829,996     Series 2019-PJ3, Class A1 (j)................................      3.50%       03/25/50             818,855



Page 34                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  JP Morgan Mortgage Trust
$          6,086     Series 2004-S2, Class 5A1....................................      5.50%       12/25/19    $          5,692
           4,175     Series 2014-IVR3, Class 2A1 (e) (j)..........................      2.34%       09/25/44               4,194
       4,401,585     Series 2015-IVR2, Class A5 (e) (j)...........................      2.24%       01/25/45           4,369,787
         841,419     Series 2018-5, Class A1 (j)..................................      3.50%       10/25/48             825,077
       1,229,051     Series 2018-5, Class A13 (j).................................      3.50%       10/25/48           1,175,771
       5,840,358     Series 2018-7FRB, Class A2, 1 Mo. LIBOR + 0.75% (a) (j)......      1.42%       04/25/46           5,818,397
       1,913,890     Series 2018-8, Class A7 (j)..................................      4.00%       01/25/49           1,894,885
       2,385,973     Series 2019-1, Class A5 (j)..................................      4.00%       05/25/49           2,366,107
         776,646     Series 2019-5, Class A15 (j).................................      4.00%       11/25/49             768,802
         797,840     Series 2019-8, Class A15 (j).................................      3.50%       03/25/50             769,382
       1,170,723     Series 2019-9, Class A11, 1 Mo. LIBOR + 0.90% (a) (j)........      1.36%       05/25/50           1,164,784
       1,479,919     Series 2019-INV2, Class A15 (j)..............................      3.50%       02/25/50           1,439,347
          11,359     Series 2019-LTV2, Class A11, 1 Mo. LIBOR +
                        0.90% (a) (j).............................................      1.57%       12/25/49              11,360
         322,356     Series 2019-LTV3, Class A15 (j)..............................      3.50%       03/25/50             320,103
      11,379,342     Series 2020-7, Class A3 (j)..................................      3.00%       01/25/51          10,641,882
       5,153,228     Series 2020-INV1, Class A15 (j)..............................      3.50%       08/25/50           4,978,004
       7,784,257     Series 2021-3, Class A11, 30 Day Average SOFR +
                        0.60% (a) (j).............................................      0.70%       07/25/51           7,557,060
       9,224,880     Series 2021-INV4, Class A2 (j)...............................      3.00%       01/25/52           8,474,638
       9,221,610     Series 2021-INV6, Class A2 (j)...............................      3.00%       04/25/52           8,466,737
                  JPMorgan Wealth Management
      10,000,000     Series 2020-ATR1, Class A5 (j)...............................      3.00%       02/25/50           9,194,680
                  MASTR Seasoned Securitization Trust
           1,003     Series 2005-2, Class 3A1.....................................      6.00%       11/25/17                 988
                  Mello Mortgage Capital Acceptance
       5,063,004     Series 2018-MTG2, Class A9 (j)...............................      4.35%       10/25/48           5,042,995
                  MetLife Securitization Trust
       3,360,898     Series 2018-1A, Class A (j)..................................      3.75%       03/25/57           3,350,380
                  MFA Trust
       7,248,377     Series 2021-NQM2, Class A1 (j)...............................      1.03%       11/25/64           6,657,896
       9,817,648     Series 2022-INV1, Class A1, steps up to 4.91% on
                        03/25/26 (j) (l)..........................................      3.91%       04/25/66           9,726,084
                  MRA Issuance Trust
       6,000,000     Series 2021-8, Class A2X, 1 Mo. LIBOR + 1.15% (a) (j)........      1.38%       05/15/22           5,988,245
                  New Residential Mortgage Loan Trust
       5,896,312     Series 2015-2A, Class B1 (j).................................      4.50%       08/25/55           5,888,705
       4,542,107     Series 2016-1A, Class A1 (j).................................      3.75%       03/25/56           4,448,752
       2,981,330     Series 2018-4A, Class A1M, 1 Mo. LIBOR + 0.90% (a) (j).......      1.57%       01/25/48           2,950,721
      26,768,503     Series 2018-4A, Class A1S, 1 Mo. LIBOR + 0.75% (a) (j).......      1.42%       01/25/48          26,493,666
       5,830,090     Series 2019-NQM5, Class A1 (j)...............................      2.71%       11/25/59           5,759,762
                  OBX Trust
       1,811,468     Series 2018-EXP1, Class 1A3 (j)..............................      4.00%       04/25/48           1,759,263
       1,941,964     Series 2018-EXP1, Class 2A1, 1 Mo. LIBOR +
                        0.85% (a) (j).............................................      1.52%       04/25/48           1,949,518
                  PRKCM Trust
       8,849,474     Series 2021-AFC1, Class A1 (j)...............................      1.51%       08/25/56           7,935,676
                  Provident Funding Mortgage Trust
       1,439,062     Series 2019-1, Class A5 (j)..................................      3.00%       12/25/49           1,375,729
       2,199,297     Series 2020-1, Class A5 (j)..................................      3.00%       02/25/50           2,101,516
                  PSMC Trust
       3,485,716     Series 2020-3, Class A1 (j)..................................      3.00%       11/25/50           3,337,296



                        See Notes to Financial Statements                Page 35





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COLLATERALIZED MORTGAGE OBLIGATIONS (CONTINUED)
                  RUN Trust
$      9,901,928     Series 2022-NQM1, Class A1 (j)...............................      4.00%       03/25/67    $      9,780,580
                  Sequoia Mortgage Trust
       2,015,425     Series 2017-2, Class A19 (j).................................      3.50%       02/25/47           1,921,089
         641,476     Series 2017-CH1, Class A13 (j)...............................      4.00%       08/25/47             636,977
       5,396,144     Series 2018-CH1, Class B1B (j)...............................      4.47%       03/25/48           5,096,855
      11,798,561     Series 2020-1, Class A7 (j)..................................      3.50%       02/25/50          11,327,675
       3,798,779     Series 2020-1, Class A19 (j).................................      3.50%       02/25/50           3,613,940
                  Starwood Mortgage Residential Trust 2022-3
       9,000,000     Series 2022-3, Class A1 (j)..................................      4.16%       03/25/67           8,988,779
                  TIAA Bank Mortgage Loan Trust
         410,720     Series 2018-3, Class A1 (j)..................................      4.00%       11/25/48             406,030
                  Towd Point Mortgage Trust
       4,066,272     Series 2018-2, Class A1 (j)..................................      3.25%       03/25/58           4,046,787
                  Verus Securitization Trust
       3,678,341     Series 2019-INV3, Class A2 (j)...............................      2.95%       11/25/59           3,674,524
       6,255,000     Series 2020-INV1, Class A3, steps up to 4.89% on
                        05/26/24 (j) (l)..........................................      3.89%       03/25/60           6,228,115
       5,597,620     Series 2021-1, Class A1 (j)..................................      0.82%       01/25/66           5,351,762
       6,500,000     Series 2022-4, Class A1, steps up to 5.47% on
                        04/25/26 (j) (l)..........................................      4.47%       04/25/67           6,520,471
                  Vista Point Securitization Trust
       4,200,000     Series 2020-1, Class M1 (j)..................................      4.15%       03/25/65           4,149,576
                  Wells Fargo Mortgage Backed Securities Trust
         583,239     Series 2019-1, Class A1 (j)..................................      3.97%       11/25/48             579,960
         265,744     Series 2019-3, Class A1 (j)..................................      3.50%       07/25/49             254,545
      14,063,683     Series 2021-INV2, Class A2 (j)...............................      2.50%       09/25/51          12,463,723
                  WinWater Mortgage Loan Trust
       1,403,324     Series 2016-1, Class 1A18 (j)................................      3.50%       01/20/46           1,353,349
         655,192     Series 2016-1, Class 2A3 (j).................................      3.00%       12/20/30             631,437
       4,081,198     Series 2016-1, Class B1 (e) (j)..............................      3.81%       01/20/46           3,951,394
                                                                                                                ----------------
                                                                                                                     461,550,058
                                                                                                                ----------------
                  COMMERCIAL MORTGAGE-BACKED SECURITIES -- 4.9%
                  Austin Fairmont Hotel Trust
       5,000,000     Series 2019-FAIR, Class A, 1 Mo. LIBOR + 1.05% (a) (j).......      1.60%       09/15/32           4,943,225
                  BAMLL Commercial Mortgage Securities Trust
       7,000,000     Series 2013-WBRK, Class A (e) (j)............................      3.53%       03/10/37           6,830,547
                  BBCMS Mortgage Trust
      12,000,000     Series 2017-DELC, Class A, 1 Mo. LIBOR + 0.85% (a) (j).......      1.40%       08/15/36          11,833,237
       8,394,000     Series 2018-TALL, Class A, 1 Mo. LIBOR + 0.72% (a) (j).......      1.28%       03/15/37           8,158,155
                  BPR Trust
       4,876,376     Series 2021-WILL, Class A, 1 Mo. LIBOR + 1.75% (a) (j).......      2.30%       06/15/38           4,809,369
      10,000,000     Series 2022-OANA, Class A, 1 Mo. CME Term SOFR +
                        1.90% (a) (j).............................................      2.25%       04/15/37          10,003,888
                  BX Commercial Mortgage Trust
      10,000,000     Series 2019-IMC, Class A, 1 Mo. LIBOR + 1.00% (a) (j)........      1.55%       04/15/34           9,865,148
                  Citigroup Commercial Mortgage Trust
       8,500,000     Series 2012-GC8, Class AS (j)................................      3.68%       09/10/45           8,501,362
       2,915,000     Series 2014-GC23, Class B....................................      4.18%       07/10/47           2,893,726
      90,666,609     Series 2016-P4, Class XA, IO (e).............................      2.05%       07/10/49           5,577,982
                  COMM Mortgage Trust
       7,450,000     Series 2012-CR3, Class AM (j)................................      3.42%       10/15/45           7,417,789



Page 36                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COMMERCIAL MORTGAGE-BACKED SECURITIES (CONTINUED)
                  COMM Mortgage Trust (Continued)
$     10,000,000     Series 2013-CR13, Class AM...................................      4.45%       11/10/46    $     10,083,335
      11,300,000     Series 2014-CR15, Class AM...................................      4.43%       02/10/47          11,337,528
       6,850,000     Series 2014-CR21, Class AM...................................      3.99%       12/10/47           6,792,326
                  DBWF Mortgage Trust
      10,844,968     Series 2018-GLKS, Class A, 1 Mo. LIBOR + 1.03% (a) (j).......      1.58%       12/19/30          10,699,484
                  Fontainebleau Miami Beach Trust
       5,000,000     Series 2019-FBLU, Class C (j)................................      3.75%       12/10/36           4,849,459
                  GS Mortgage Securities Corp Trust
      14,050,000     Series 2019-BOCA, Class A, 1 Mo. LIBOR + 1.20% (a) (j).......      1.75%       06/15/38          14,044,400
                  GS Mortgage Securities Corp. II
      10,717,000     Series 2012-TMSQ, Class A (j)................................      3.01%       12/10/30          10,693,597
                  GS Mortgage Securities Trust
       3,985,930     Series 2014-GC18, Class A3...................................      3.80%       01/10/47           3,977,900
                  Hawaii Hotel Trust
       9,290,000     Series 2019-MAUI, Class A, 1 Mo. LIBOR + 1.15% (a) (j).......      1.70%       05/15/38           9,190,181
                  J.P. Morgan Chase Commercial Mortgage Securities Trust
       9,690,857     Series 2018-PHH, Class A, 1 Mo. LIBOR + 1.06%, 2.56%
                        Floor (a) (j).............................................      2.56%       06/15/35           9,512,926
                  MHC Commercial Mortgage Trust
       6,335,000     Series 2021-MHC, Class A, 1 Mo. LIBOR + 0.80% (a) (j)........      1.36%       04/15/38           6,220,579
                  Morgan Stanley Bank of America Merrill Lynch Trust
       8,015,000     Series 2014-C15, Class AS....................................      4.26%       04/15/47           8,038,867
                  Motel Trust
       6,240,231     Series 2021-MTL6, Class A, 1 Mo. LIBOR + 0.90% (a) (j).......      1.45%       09/15/38           6,150,766
                  RBS Commercial Funding, Inc. Trust
       7,045,000     Series 2013-GSP, Class A (e) (j).............................      3.96%       01/15/32           7,024,198
                  Ready Capital Mortgage Financing LLC
       9,800,000     Series 2021-FL6, Class A, 1 Mo. LIBOR + 0.95% (a) (j)........      1.62%       07/25/36           9,614,515
                  RIAL 2022-FL8 Issuer Ltd.
       4,428,000     Series 2022-FL8, Class A (a) (f) (g) (j).....................      0.00%       01/19/27           4,428,000
                  UBS-Barclays Commercial Mortgage Trust
       5,856,000     Series 2012-C3, Class B (e) (j)..............................      4.37%       08/10/49           5,865,455
      12,250,000     Series 2013-C5, Class A4.....................................      3.18%       03/10/46          12,257,421
                  VMC Finance LLC
       3,932,999     Series 2021-HT1, Class A, 1 Mo. LIBOR + 1.65% (a) (j)........      2.20%       01/18/37           3,935,455
                  Wells Fargo Commercial Mortgage Trust
      12,980,000     Series 2012-LC5, Class B.....................................      4.14%       10/15/45          13,015,182
       4,379,333     Series 2015-LC22, Class ASB..................................      3.57%       09/15/58           4,384,823
       7,500,000     Series 2015-NXS2, Class B (e)................................      4.43%       07/15/58           7,429,532
      67,592,329     Series 2016-C37, Class XA, IO (e)............................      0.96%       12/15/49           1,921,434
       5,450,000     Series 2020-SDAL, Class C, 1 Mo. LIBOR + 1.74% (a) (j).......      2.29%       02/15/37           5,319,919
                  WFRBS Commercial Mortgage Trust
       4,292,804     Series 2013-C18, Class A4....................................      3.90%       12/15/46           4,291,739
                                                                                                                ----------------
                                                                                                                     271,913,449
                                                                                                                ----------------
                  TOTAL MORTGAGE-BACKED SECURITIES............................................................       733,463,507
                  (Cost $758,160,386)                                                                           ----------------



                        See Notes to Financial Statements                Page 37





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
ASSET-BACKED SECURITIES -- 4.6%
                  Affirm Asset Securitization Trust
$      8,160,000     Series 2021-A, Class A (j)...................................      0.88%       08/15/25    $      8,112,856
                  American Credit Acceptance Receivables Trust
      12,806,519     Series 2022-1, Class A (j)...................................      0.99%       12/15/25          12,687,756
       9,000,000     Series 2022-1, Class B (j)...................................      1.68%       09/14/26           8,704,360
       6,000,000     Series 2022-2, Class A (j)...................................      2.66%       02/13/26           6,012,104
                  AMSR Trust
       2,500,000     Series 2020-SFR2, Class A (j)................................      1.63%       07/17/37           2,334,221
       6,393,000     Series 2020-SFR5, Class A (j)................................      1.38%       11/17/37           5,852,470
                  CIG Auto Receivables Trust
       6,873,355     Series 2021-1A, Class A (j)..................................      0.69%       04/14/25           6,776,859
                  Corevest American Finance Trust
      13,651,866     Series 2020-3, Class A (j)...................................      1.36%       08/15/53          12,335,269
       6,290,001     Series 2020-4, Class A (j)...................................      1.17%       12/15/52           5,725,351
                  CWABS, Inc. Asset-Backed Certificates Trust
       3,260,981     Series 2004-5, Class M1, 1 Mo. LIBOR + 0.86% (a).............      1.52%       08/25/34           3,236,150
                  Diamond Resorts Owner Trust
       7,007,196     Series 2021-1A, Class A (j)..................................      1.51%       11/21/33           6,682,001
                  DT Auto Owner Trust
       5,657,982     Series 2021-4A, Class A (j)..................................      0.56%       09/15/25           5,582,030
                  FCI Funding LLC
       3,762,421     Series 2019-1A, Class A (j)..................................      3.63%       02/18/31           3,774,742
                  Flagship Credit Auto Trust
      22,220,669     Series 2021-4, Class A (j)...................................      0.81%       07/17/26          21,644,267
      13,922,778     Series 2022-1, Class A (j)...................................      1.79%       10/15/26          13,697,771
                  FNA VI LLC
       9,179,482     Series 2021-1A, Class A (j)..................................      1.35%       01/10/32           8,713,166
                  Foursight Capital Automobile Receivables Trust
      14,285,000     Series 2022-1, Class A2 (j)..................................      1.15%       09/15/25          14,057,250
                  GLS Auto Receivables Issuer Trust
      23,235,975     Series 2021-4A, Class A (j)..................................      0.84%       07/15/25          22,969,830
                  GSAMP Trust
       6,120,540     Series 2006-SEA1, Class M2, 1 Mo. LIBOR + 1.65% (a) (j)......      2.32%       05/25/36           6,097,782
                  M360 Ltd.
       5,000,000     Series 2021-CRE3, Class A, 1 Mo. LIBOR + 1.50% (a) (j).......      2.13%       11/22/38           4,918,750
                  MF1 Ltd.
       4,000,000     Series 2021-FL7, Class A, 1 Mo. LIBOR + 1.08% (a) (j)........      1.63%       10/16/36           3,932,500
                  Mill City Mortgage Loan Trust
       1,505,984     Series 2018-1, Class A1 (j)..................................      3.25%       05/25/62           1,495,354
       1,553,712     Series 2018-2, Class A1 (e) (j)..............................      3.50%       05/25/58           1,543,578
                  Oscar US Funding XIV LLC
      10,750,000     Series 2022-1A, Class A2 (j).................................      1.60%       03/10/25          10,603,491
                  Santander Drive Auto Receivables Trust
      10,115,000     Series 2021-4, Class A3......................................      0.51%       08/15/25           9,990,688
       9,500,000     Series 2022-1, Class A3......................................      1.94%       11/17/25           9,351,586
                  Sierra Timeshare Receivables Funding LLC
       2,517,469     Series 2019-1A, Class A (j)..................................      3.20%       01/20/36           2,493,526
       5,455,709     Series 2020-2A, Class A (j)..................................      1.33%       07/20/37           5,182,927
                  Towd Point Mortgage Trust
          73,714     Series 2015-3, Class A4B (j).................................      3.50%       03/25/54              73,902
       2,937,459     Series 2019-1, Class A1 (j)..................................      3.66%       03/25/58           2,901,499
                  United Auto Credit Securitization Trust
       7,938,794     Series 2022-1, Class A (j)...................................      1.11%       07/10/24           7,910,735



Page 38                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
ASSET-BACKED SECURITIES (CONTINUED)
                  Westlake Automobile Receivables Trust
$     10,750,000     Series 2021-3A, Class A3 (j).................................      0.95%       06/16/25    $     10,478,865
      10,000,000     Series 2022-1A, Class A3 (j).................................      2.42%       07/15/25           9,861,756
                                                                                                                ----------------
                  TOTAL ASSET-BACKED SECURITIES...............................................................       255,735,392
                  (Cost $262,246,312)                                                                           ----------------





     SHARES                                               DESCRIPTION                                                VALUE
----------------  --------------------------------------------------------------------------------------------  ----------------
                                                                                                          
EXCHANGE-TRADED FUNDS -- 0.0%
                  CAPITAL MARKETS -- 0.0%
          29,359  First Trust Long Duration Opportunities ETF (m).............................................           716,360
                  (Cost $805,933)                                                                               ----------------

MONEY MARKET FUNDS -- 8.0%

     160,513,072  BlackRock Treasury Trust Fund - Institutional Shares - 0.35% (n)............................       160,513,072
     280,309,642  Morgan Stanley Institutional Liquidity Funds - Treasury Portfolio - Institutional Shares -
                     0.23% (n)................................................................................       280,309,642
                                                                                                                ----------------
                  TOTAL MONEY MARKET FUNDS....................................................................       440,822,714
                  (Cost $440,822,714)                                                                           ----------------

                  TOTAL INVESTMENTS -- 111.5%.................................................................     6,157,780,876
                  (Cost $6,401,336,376)                                                                         ----------------





   NUMBER OF                                                           NOTIONAL       EXERCISE     EXPIRATION
   CONTRACTS                         DESCRIPTION                        AMOUNT         PRICE          DATE           VALUE
----------------  -------------------------------------------------  -------------  ------------  ------------  ----------------
                                                                                                 
PUT OPTIONS PURCHASED -- 0.0%
             150  U.S. 5-Year Treasury Futures Put.................  $  16,900,781  $     117.00    05/20/22             651,562
             250  U.S. Treasury Long Bond Futures Put..............     35,171,875        138.00    05/20/22             242,188
                                                                                                                ----------------
                  TOTAL PUT OPTIONS PURCHASED.................................................................           893,750
                  (Cost $306,642)                                                                               ----------------





   PRINCIPAL                                                                           STATED        STATED
     VALUE                                  DESCRIPTION                                COUPON       MATURITY         VALUE
----------------  ----------------------------------------------------------------  ------------  ------------  ----------------
                                                                                                    
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES SOLD SHORT -- (21.2)%
                  Federal National Mortgage Association
$    (15,000,000)    Pool TBA.....................................................      2.50%       05/15/52         (13,700,391)
     (30,000,000)    Pool TBA.....................................................      3.50%       05/15/52         (29,137,500)
    (102,000,000)    Pool TBA.....................................................      4.00%       05/15/52        (101,559,726)
    (135,000,000)    Pool TBA.....................................................      3.00%       06/15/52        (127,193,111)
     (15,000,000)    Pool TBA.....................................................      3.50%       06/15/52         (14,533,639)
    (242,500,000)    Pool TBA (k).................................................      1.50%       06/15/37        (221,696,097)
    (175,000,000)    Pool TBA (k).................................................      1.50%       07/15/37        (159,760,811)
    (346,000,000)    Pool TBA (k).................................................      2.00%       06/15/52        (305,090,423)
    (225,000,000)    Pool TBA (k).................................................      2.00%       07/15/52        (198,069,914)
                                                                                                                ----------------
                  TOTAL U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES SOLD SHORT..........................    (1,170,741,612)
                  (Proceeds $1,195,190,937)                                                                     ----------------



                        See Notes to Financial Statements                Page 39





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)



   NUMBER OF                                                           NOTIONAL       EXERCISE     EXPIRATION
   CONTRACTS                         DESCRIPTION                        AMOUNT         PRICE          DATE           VALUE
----------------  -------------------------------------------------  -------------  ------------  ------------  ----------------
                                                                                                 
WRITTEN OPTIONS -- (0.0)%
                  CALL OPTIONS WRITTEN -- (0.0)%
            (100) U.S. 5-Year Treasury Futures Call................  $ (11,267,187) $     114.75    05/20/22    $         (7,031)
            (100) U.S. 10-Year Treasury Futures Call...............    (11,915,625)       127.00    05/20/22              (3,125)
            (350) U.S. Treasury Long Bond Futures Call.............    (49,240,625)       145.00    05/20/22            (207,813)
                                                                                                                ----------------
                  TOTAL CALL OPTIONS WRITTEN..................................................................          (217,969)
                  (Premiums received $312,243)                                                                  ----------------

PUT OPTIONS WRITTEN -- (0.0)%
            (100) U.S. 5-Year Treasury Futures Put.................    (11,267,187)       113.00    05/20/22             (80,469)
            (100) U.S. 5-Year Treasury Futures Put.................    (11,267,187)       114.00    05/20/22            (149,219)
             (50) U.S. 5-Year Treasury Futures Put.................     (5,633,594)       116.00    05/20/22            (167,578)
             (50) U.S. 10-Year Treasury Futures Put................     (6,450,000)       129.00    05/20/22             (70,312)
                                                                                                                ----------------
                  TOTAL PUT OPTIONS WRITTEN...................................................................          (467,578)
                  (Premiums received $202,737)                                                                  ----------------

                  TOTAL WRITTEN OPTIONS.......................................................................          (685,547)
                  (Premiums received $514,980)                                                                  ----------------

                  NET OTHER ASSETS AND LIABILITIES -- 9.7%....................................................       537,785,790
                                                                                                                ----------------
                  NET ASSETS -- 100.0%........................................................................  $  5,525,033,257
                                                                                                                ================



FUTURES CONTRACTS AT APRIL 30, 2022 (See Note 2D - Futures Contracts in the
Notes to Financial Statements):



                                                                                                                   UNREALIZED
                                                                                                                  APPRECIATION
                                                                      NUMBER OF   EXPIRATION      NOTIONAL      (DEPRECIATION)/
                  FUTURES CONTRACTS                      POSITION     CONTRACTS      DATE           VALUE            VALUE
------------------------------------------------------  -----------  -----------  -----------  ---------------  ----------------
                                                                                                 
U.S. 2-Year Treasury Notes                                 Short          150      Jun-2022    $   (31,621,875) $         82,850
U.S. 5-Year Treasury Notes                                 Short        2,249      Jun-2022       (253,399,047)        1,392,579
U.S. 10-Year Treasury Notes                                Short          251      Jun-2022        (29,908,219)          (16,308)
Ultra 10-Year U.S. Treasury Notes                          Short        6,686      Jun-2022       (862,494,000)       52,621,536
U.S. Treasury Long Bond Futures                            Short        1,479      Jun-2022       (208,076,813)        7,943,758
Ultra U.S. Treasury Bond Futures                           Short          225      Jun-2022        (36,098,437)          446,819
                                                                                               ---------------  ----------------
                                                                                               $(1,421,598,391) $     62,471,234
                                                                                               ===============  ================


-----------------------------

(a)   Floating or variable rate security.

(b)   Zero coupon security.

(c)   Inverse floating rate security.

(d)   Weighted Average Coupon security. Coupon is based on the blended interest
      rate of the underlying holdings, which may have different coupons. The
      coupon may change in any period.

(e)   Collateral Strip Rate security. Coupon is based on the weighted net
      interest rate of the investment's underlying collateral. The interest rate
      resets periodically.

(f)   This security is fair valued by the Advisor's Pricing Committee in
      accordance with procedures adopted by the Trust's Board of Trustees, and
      in accordance with provisions of the Investment Company Act of 1940, as
      amended. At April 30, 2022, securities noted as such are valued at
      $378,082,807 or 6.8% of net assets.

(g)   When-issued security. The interest rate shown reflects the rate in effect
      at April 30, 2022. Interest will begin accruing on the security's first
      settlement date.

(h)   Pursuant to procedures adopted by the Trust's Board of Trustees, this
      security has been determined to be illiquid by First Trust Advisors L.P.
      (the "Advisor"), the Fund's advisor.

(i)   This security's value was determined using significant unobservable inputs
      (see Note 2A - Portfolio Valuation in the Notes to Financial Statements).


Page 40                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

PORTFOLIO OF INVESTMENTS (CONTINUED)
APRIL 30, 2022 (UNAUDITED)

(j)   This security, sold within the terms of a private placement memorandum, is
      exempt from registration upon resale under Rule 144A of the Securities Act
      of 1933, as amended and may be resold in transactions exempt from
      registration, normally to qualified institutional buyers. Pursuant to
      procedures adopted by the Trust's Board of Trustees, this security has
      been determined to be liquid by the Advisor. Although market instability
      can result in periods of increased overall market illiquidity, liquidity
      for each security is determined based on security specific factors and
      assumptions, which require subjective judgment. At April 30, 2022,
      securities noted as such amounted to $946,136,364 or 17.1% of net assets.

(k)   All or a portion of this security is part of a mortgage dollar roll
      agreement (see Note 2I- Mortgage Dollar Rolls and TBA Transactions in the
      Notes to Financial Statements).

(l)   Step-up security. A security where the coupon increases or steps up at a
      predetermined date.

(m)   Investment in an affiliated fund.

(n)   Rate shown reflects yield as of April 30, 2022.

IO    - Interest-Only Security - Principal amount shown represents par value on
      which interest payments are based.

LIBOR - London Interbank Offered Rate

PO    - Principal-Only Security

REMIC - Real Estate Mortgage Investment Conduit

SOFR  - Secured Overnight Financing Rate

STRIPS - Separate Trading of Registered Interest and Principal of Securities

TBA   - To-Be-Announced Security

-----------------------------

VALUATION INPUTS

A summary of the inputs used to value the Fund's investments as of April 30,
2022 is as follows (see Note 2A - Portfolio Valuation in the Notes to Financial
Statements):



                                                          ASSETS TABLE
                                                                                                  LEVEL 2            LEVEL 3
                                                             TOTAL             LEVEL 1          SIGNIFICANT        SIGNIFICANT
                                                           VALUE AT            QUOTED           OBSERVABLE        UNOBSERVABLE
                                                           4/30/2022           PRICES             INPUTS             INPUTS
                                                        ---------------    ---------------    ---------------    ---------------
                                                                                                     
U.S. Government Agency Mortgage-Backed Securities.....  $ 4,727,042,903    $            --    $ 4,705,717,343    $    21,325,560
Mortgage-Backed Securities............................      733,463,507                 --        733,463,507                 --
Asset-Backed Securities...............................      255,735,392                 --        255,735,392                 --
Exchange-Traded Funds*................................          716,360            716,360                 --                 --
Money Market Funds....................................      440,822,714        440,822,714                 --                 --
                                                        ---------------    ---------------    ---------------    ---------------
Total Investments.....................................    6,157,780,876        441,539,074      5,694,916,242         21,325,560
Put Options Purchased.................................          893,750            893,750                 --                 --
Futures Contracts**...................................       62,487,542         62,487,542                 --                 --
                                                        ---------------    ---------------    ---------------    ---------------
Total.................................................  $ 6,221,162,168    $   504,920,366    $ 5,694,916,242    $    21,325,560
                                                        ===============    ===============    ===============    ===============

                                                       LIABILITIES TABLE
                                                                                                  LEVEL 2            LEVEL 3
                                                             TOTAL             LEVEL 1          SIGNIFICANT        SIGNIFICANT
                                                           VALUE AT            QUOTED           OBSERVABLE        UNOBSERVABLE
                                                           4/30/2022           PRICES             INPUTS             INPUTS
                                                        ---------------    ---------------    ---------------    ---------------
U.S. Government Agency Mortgage-Backed Securities
   Sold Short.........................................  $(1,170,741,612)   $            --    $(1,170,741,612)   $            --
Call Options Written..................................         (217,969)          (217,969)                --                 --
Put Options Written...................................         (467,578)          (467,578)                --                 --
Futures Contracts**...................................          (16,308)           (16,308)                --                 --
                                                        ---------------    ---------------    ---------------    ---------------
Total.................................................  $(1,171,443,467)   $      (701,855)   $(1,170,741,612)   $            --
                                                        ===============    ===============    ===============    ===============


*  See Portfolio of Investments for industry breakout.

** Includes cumulative appreciation/depreciation on futures contracts as
reported in the Futures Contracts table. Only the current day's variation margin
is presented on the Statement of Assets and Liabilities.

Level 3 Investments that are fair valued by the Advisor's Pricing Committee are
footnoted in the Portfolio of Investments. All Level 3 values are based on
unobservable inputs.


                        See Notes to Financial Statements                Page 41





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

STATEMENT OF ASSETS AND LIABILITIES
APRIL 30, 2022 (UNAUDITED)



ASSETS:
                                                                          
Investments, at value - Unaffiliated......................................   $ 6,157,064,516
Investments, at value - Affiliated........................................           716,360
                                                                             ---------------
Total investments, at value...............................................     6,157,780,876
Options contracts purchased, at value.....................................           893,750
Cash......................................................................       505,789,520
Cash segregated as collateral for open futures and options contracts......        26,799,708
Receivables:
   Investment securities sold.............................................     6,561,698,184
   Interest...............................................................        19,938,053
   Variation margin.......................................................         3,047,363
   Dividends..............................................................            94,801
                                                                             ---------------
   Total Assets...........................................................    13,276,042,255
                                                                             ---------------
LIABILITIES:
Investments sold short, at value (proceeds $1,195,190,937)................     1,170,741,612
Options contracts written, at value.......................................           685,547
Payables:
   Investment securities purchased........................................     6,576,585,930
   Investment advisory fees...............................................         2,987,516
   Other Liabilities......................................................             8,393
                                                                             ---------------
   Total Liabilities......................................................     7,751,008,998
                                                                             ---------------
NET ASSETS................................................................   $ 5,525,033,257
                                                                             ===============
NET ASSETS CONSIST OF:
Paid-in capital...........................................................   $ 5,778,949,653
Par value.................................................................         1,133,500
Accumulated distributable earnings (loss).................................      (255,049,896)
                                                                             ---------------
NET ASSETS................................................................   $ 5,525,033,257
                                                                             ---------------
NET ASSET VALUE, per share................................................   $         48.74
                                                                             ===============
Number of shares outstanding (unlimited number of shares authorized,
   par value $0.01 per share).............................................       113,350,002
                                                                             ===============
Investments, at cost - Unaffiliated.......................................   $ 6,400,530,443
                                                                             ===============
Investments, at cost - Affiliated.........................................   $       805,933
                                                                             ===============
Total investments, at cost................................................   $ 6,401,336,376
                                                                             ===============
Premiums paid on options contracts purchased..............................   $       306,642
                                                                             ===============
Premiums received on options contracts written............................   $       514,980
                                                                             ===============



Page 42                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

STATEMENT OF OPERATIONS
FOR THE SIX MONTHS ENDED APRIL 30, 2022 (UNAUDITED)



INVESTMENT INCOME:
                                                                          
Interest..................................................................   $    51,321,672
Dividends - Unaffiliated..................................................           175,445
Dividends - Affiliated....................................................             5,983
                                                                             ---------------
   Total investment income................................................        51,503,100
                                                                             ---------------
EXPENSES:
Investment advisory fees..................................................        19,467,475
                                                                             ---------------
   Total expenses.........................................................        19,467,475
                                                                             ---------------
NET INVESTMENT INCOME (LOSS)..............................................        32,035,625
                                                                             ---------------
REALIZED AND UNREALIZED GAIN (LOSS):
Net realized gain (loss) on:
   Investments - Unaffiliated.............................................      (151,986,679)
   Investments - Affiliated...............................................                --
   Investments sold short.................................................        71,813,246
   Futures contracts......................................................        80,199,556
   Purchased options contracts............................................        (1,165,816)
   Written options contracts..............................................         7,195,714
                                                                             ---------------
Net realized gain (loss)..................................................         6,056,021
                                                                             ---------------
Net change in unrealized appreciation (depreciation) on:
   Investments - Unaffiliated.............................................      (254,624,452)
   Investments - Affiliated...............................................           (97,178)
   Investments sold short.................................................        23,932,727
   Futures contracts......................................................        48,023,510
   Purchased options contracts............................................           587,108
   Written options contracts..............................................           792,889
                                                                             ---------------
Net change in unrealized appreciation (depreciation)......................      (181,385,396)
                                                                             ---------------
NET REALIZED AND UNREALIZED GAIN (LOSS)...................................      (175,329,375)
                                                                             ---------------
NET INCREASE (DECREASE) IN NET ASSETS RESULTING
   FROM OPERATIONS........................................................   $  (143,293,750)
                                                                             ===============



                        See Notes to Financial Statements                Page 43





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

STATEMENTS OF CHANGES IN NET ASSETS



                                                                               SIX MONTHS
                                                                                  ENDED              YEAR
                                                                                4/30/2022           ENDED
                                                                               (UNAUDITED)        10/31/2021
                                                                             ---------------    --------------
                                                                                          
OPERATIONS:
Net investment income (loss)..............................................   $    32,035,625    $   50,844,582
Net realized gain (loss)..................................................         6,056,021        31,189,777
Net change in unrealized appreciation (depreciation)......................      (181,385,396)      (86,269,103)
                                                                             ---------------    --------------
Net increase (decrease) in net assets resulting from operations...........      (143,293,750)       (4,234,744)
                                                                             ---------------    --------------

DISTRIBUTIONS TO SHAREHOLDERS FROM:
Investment operations.....................................................       (55,858,126)      (48,092,827)
Return of capital.........................................................                --       (90,717,550)
                                                                             ---------------    --------------
Total distributions to shareholders.......................................       (55,858,126)     (138,810,377)
                                                                             ---------------    --------------

SHAREHOLDER TRANSACTIONS:
Proceeds from shares sold.................................................                --     1,099,737,143
Cost of shares redeemed...................................................    (1,056,782,579)     (565,466,073)
                                                                             ---------------    --------------
Net increase (decrease) in net assets resulting from
   shareholder transactions...............................................    (1,056,782,579)      534,271,070
                                                                             ---------------    --------------
Total increase (decrease) in net assets...................................    (1,255,934,455)      391,225,949

NET ASSETS:
Beginning of period.......................................................     6,780,967,712     6,389,741,763
                                                                             ---------------    --------------
End of period.............................................................   $ 5,525,033,257    $6,780,967,712
                                                                             ===============    ==============
CHANGES IN SHARES OUTSTANDING:
Shares outstanding, beginning of period...................................       134,550,002       124,200,002
Shares sold...............................................................                --        21,450,000
Shares redeemed...........................................................       (21,200,000)      (11,100,000)
                                                                             ---------------    --------------
Shares outstanding, end of period.........................................       113,350,002       134,550,002
                                                                             ===============    ==============



Page 44                 See Notes to Financial Statements





FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)

FINANCIAL HIGHLIGHTS
FOR A SHARE OUTSTANDING THROUGHOUT EACH PERIOD



                                           SIX MONTHS
                                             ENDED                                 YEAR ENDED OCTOBER 31,
                                           4/30/2022     --------------------------------------------------------------------------
                                          (UNAUDITED)        2021           2020           2019           2018            2017
                                          ------------   ------------   ------------   ------------   ------------   --------------
                                                                                                      
Net asset value, beginning of period.....  $    50.40     $    51.45     $    51.87     $    50.78     $    51.76       $  52.54
                                           ----------     ----------     ----------     ----------     ----------       --------
INCOME FROM INVESTMENT OPERATIONS:
Net investment income (loss).............        0.27           0.39           0.87           1.24           1.17           1.13
Net realized and unrealized gain (loss)..       (1.46)         (0.40)         (0.10)          1.21          (0.74)         (0.50)
                                           ----------     ----------     ----------     ----------     ----------       --------
Total from investment operations.........       (1.19)         (0.01)          0.77           2.45           0.43           0.63
                                           ----------     ----------     ----------     ----------     ----------       --------
DISTRIBUTIONS PAID TO SHAREHOLDERS FROM:
Net investment income....................       (0.47)         (0.36)         (0.99)         (1.23)         (1.13)         (1.14)
Net realized gain........................          --             --             --          (0.05)         (0.28)         (0.02)
Return of capital........................          --          (0.68)         (0.20)         (0.08)            --          (0.25)
                                           ----------     ----------     ----------     ----------     ----------       --------
Total distributions......................       (0.47)         (1.04)         (1.19)         (1.36)         (1.41)         (1.41)
                                           ----------     ----------     ----------     ----------     ----------       --------
Net asset value, end of period...........  $    48.74     $    50.40     $    51.45     $    51.87     $    50.78       $  51.76
                                           ==========     ==========     ==========     ==========     ==========       ========
TOTAL RETURN (a).........................       (2.36)%        (0.02)%         1.50%          4.88%          0.84%          1.22%

RATIOS/SUPPLEMENTAL DATA:
Net assets, end of period (in 000's).....  $5,525,033     $6,780,968     $6,389,742     $3,765,469     $1,729,078       $846,322
RATIOS TO AVERAGE NET ASSETS:
Ratio of total expenses to average net
   assets (b)............................        0.65% (c)      0.65%          0.65%          0.65%          0.65%          0.65%
Ratio of net investment income (loss) to
   average net assets....................        1.07% (c)      0.75%          1.57%          2.41%          2.32%          2.20%
Portfolio turnover rate (d) (e)..........         394%           495%           434%           373%           331%           190%


(a)   Total return is calculated assuming an initial investment made at the net
      asset value at the beginning of the period, reinvestment of all
      distributions at net asset value during the period, and redemption at net
      asset value on the last day of the period. The returns presented do not
      reflect the deduction of taxes that a shareholder would pay on Fund
      distributions or the redemption or sale of Fund shares. Total return is
      calculated for the time period presented and is not annualized for periods
      of less than a year.

(b)   The Fund indirectly bears its proportionate share of fees and expenses
      incurred by the underlying funds in which the Fund invests. This ratio
      does not include these indirect fees and expenses.

(c)   Annualized.

(d)   Portfolio turnover is calculated for the time period presented and is not
      annualized for periods of less than a year and does not include securities
      received or delivered from processing creations or redemptions and in-kind
      transactions.

(e)   The portfolio turnover rate not including mortgage dollar rolls was 301%
      for the six months ended April 30, 2022, and 368%, 245%, 246%, 117% and
      97% for the years ended October 31, 2021, 2020, 2019, 2018 and 2017,
      respectively.


                        See Notes to Financial Statements                Page 45





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NOTES TO FINANCIAL STATEMENTS
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               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

                                1. ORGANIZATION

First Trust Exchange-Traded Fund IV (the "Trust") is an open-end management
investment company organized as a Massachusetts business trust on September 15,
2010, and is registered with the Securities and Exchange Commission under the
Investment Company Act of 1940, as amended (the "1940 Act").

The Trust currently consists of eleven funds that are offering shares. This
report covers the First Trust Low Duration Opportunities ETF (the "Fund"), a
diversified series of the Trust, which trades under the ticker "LMBS" on The
Nasdaq Stock Market LLC ("Nasdaq"). The Fund represents a separate series of
shares of beneficial interest in the Trust. Unlike conventional mutual funds,
the Fund issues and redeems shares on a continuous basis, at net asset value
("NAV"), only in large blocks of shares known as "Creation Units."

The Fund is an actively managed exchange-traded fund ("ETF"). The Fund's primary
investment objective is to generate current income. The Fund's secondary
investment objective is to provide capital appreciation. The Fund seeks to
achieve its investment objectives by investing, under normal market conditions,
at least 60% of its net assets (including investment borrowings) in
mortgage-related debt securities and other mortgage-related instruments
(collectively, "Mortgage-Related Investments"). The Fund normally expects to
invest in Mortgage-Related Investments tied to residential and commercial
mortgages. Mortgage-Related Investments include residential mortgage-backed
securities, commercial mortgage-backed securities, stripped mortgage-backed
securities, collateralized mortgage obligations and real estate mortgage
investment conduits. The Fund may also invest in investment companies, including
ETFs, that invest primarily in Mortgage-Related Investments. The Fund will limit
its investments in Mortgage-Related Investments that are not issued or
guaranteed by Government Entities(1) to 20% of its net assets (including
investment borrowings). The Fund may invest, without limitation, in mortgage
dollar rolls. The Fund intends to enter into mortgage dollar rolls only with
high quality securities dealers and banks, as determined by the Fund's
investment advisor, First Trust Advisors L.P. ("First Trust" or the "Advisor").
The Fund may also invest in to-be-announced transactions ("TBA Transactions").
Further, the Fund may enter into short sales as part of its overall portfolio
management strategies or to offset a potential decline in the value of a
security; however, the Fund does not expect, under normal market conditions, to
engage in short sales with respect to more than 30% of the value of its net
assets (including investment borrowings). Although the Fund intends to invest
primarily in investment grade securities, the Fund may invest up to 20% of its
net assets (including investment borrowings) in securities of any credit
quality, including securities that are below investment grade, which are also
known as high yield securities, or commonly referred to as "junk" bonds, or
unrated securities that have not been judged by the Advisor to be of comparable
quality to rated investment grade securities. In the case of a split rating
between one or more of the nationally recognized statistical rating
organizations, the Fund will consider the highest rating. The Fund targets an
estimated effective duration of three years or less.

                       2. SIGNIFICANT ACCOUNTING POLICIES

The Fund is considered an investment company and follows accounting and
reporting guidance under Financial Accounting Standards Board Accounting
Standards Codification Topic 946, "Financial Services-Investment Companies." The
following is a summary of significant accounting policies consistently followed
by the Fund in the preparation of the financial statements. The preparation of
the financial statements in accordance with accounting principles generally
accepted in the United States of America ("U.S. GAAP") requires management to
make estimates and assumptions that affect the reported amounts and disclosures
in the financial statements. Actual results could differ from those estimates.

A. PORTFOLIO VALUATION

The Fund's NAV is determined daily as of the close of regular trading on the New
York Stock Exchange ("NYSE"), normally 4:00 p.m. Eastern time, on each day the
NYSE is open for trading. If the NYSE closes early on a valuation day, the NAV
is determined as of that time. Domestic debt securities and foreign securities
are priced using data reflecting the earlier closing of the principal markets
for those securities. The Fund's NAV is calculated by dividing the value of all
assets of the Fund (including accrued interest and dividends), less all
liabilities (including accrued expenses and dividends declared but unpaid), by
the total number of shares outstanding.

The Fund's investments are valued daily at market value or, in the absence of
market value with respect to any portfolio securities, at fair value. Market
value prices represent last sale or official closing prices from a national or
foreign exchange (i.e., a regulated market) and are primarily obtained from
third-party pricing services. Fair value prices represent any prices not
considered market value prices and are either obtained from a third-party
pricing service or are determined by the Advisor's Pricing Committee, in

-----------------------------
(1)   "Government Entities" means the U.S. government, its agencies and
      instrumentalities, and U.S. government-sponsored entities.


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NOTES TO FINANCIAL STATEMENTS (CONTINUED)
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               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

accordance with valuation procedures adopted by the Trust's Board of Trustees,
and in accordance with provisions of the 1940 Act. Investments valued by the
Advisor's Pricing Committee, if any, are footnoted as such in the footnotes to
the Portfolio of Investments. The Fund's investments are valued as follows:

      U.S. government securities, mortgage-backed securities, asset-backed
      securities and other debt securities are fair valued on the basis of
      valuations provided by dealers who make markets in such securities or by a
      third-party pricing service approved by the Trust's Board of Trustees,
      which may use the following valuation inputs when available:

            1)    benchmark yields;
            2)    reported trades;
            3)    broker/dealer quotes;
            4)    issuer spreads;
            5)    benchmark securities;
            6)    bids and offers; and
            7)    reference data including market research publications.

      Pricing services generally value fixed-income securities assuming orderly
      transactions of an institutional round lot size, but a Fund may hold or
      transact in such securities in smaller, odd lot sizes. Odd lots may trade
      at lower prices than institutional round lots.

      Securities traded in an over-the-counter market are fair valued at the
      mean of their most recent bid and asked price, if available, and otherwise
      at their closing bid price.

      Common stocks and other equity securities listed on any national or
      foreign exchange (excluding Nasdaq and the London Stock Exchange
      Alternative Investment Market ("AIM")) are valued at the last sale price
      on the exchange on which they are principally traded or, for Nasdaq and
      AIM securities, the official closing price. Securities traded on more than
      one securities exchange are valued at the last sale price or official
      closing price, as applicable, at the close of the securities exchange
      representing the principal market for such securities.

      Shares of open-end funds are valued at fair value which is based on NAV
      per share.

      Exchange-traded futures contracts are valued at the closing price in the
      market where such contracts are principally traded. If no closing price is
      available, exchange-traded futures contracts are fair valued at the mean
      of their most recent bid and asked price, if available, and otherwise at
      their closing bid price.

      Exchange-traded options contracts are valued at the closing price in the
      market where such contracts are principally traded. If no closing price is
      available, exchange-traded options contracts are fair valued at the mean
      of their most recent bid and asked price, if available, and otherwise at
      their closing bid price.

      Fixed income and other debt securities having a remaining maturity of
      sixty days or less when purchased are fair valued at cost adjusted for
      amortization of premiums and accretion of discounts (amortized cost),
      provided the Advisor's Pricing Committee has determined that the use of
      amortized cost is an appropriate reflection of fair value given market and
      issuer-specific conditions existing at the time of the determination.
      Factors that may be considered in determining the appropriateness of the
      use of amortized cost include, but are not limited to, the following:

            1)    the credit conditions in the relevant market and changes
                  thereto;
            2)    the liquidity conditions in the relevant market and changes
                  thereto;
            3)    the interest rate conditions in the relevant market and
                  changes thereto (such as significant changes in interest
                  rates);
            4)    issuer-specific conditions (such as significant credit
                  deterioration); and
            5)    any other market-based data the Advisor's Pricing Committee
                  considers relevant. In this regard, the Advisor's Pricing
                  Committee may use last-obtained market-based data to assist it
                  when valuing portfolio securities using amortized cost.

Certain securities may not be able to be priced by pre-established pricing
methods. Such securities may be valued by the Trust's Board of Trustees or its
delegate, the Advisor's Pricing Committee, at fair value. These securities
generally include, but are not limited to, restricted securities (securities
which may not be publicly sold without registration under the Securities Act of
1933, as amended) for which a third-party pricing service is unable to provide a
market price; securities whose trading has been formally suspended; a security
whose market or fair value price is not available from a pre-established pricing
source; a security with respect to which an event has occurred that is likely to
materially affect the value of the security after the market has closed but


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NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

before the calculation of the Fund's NAV or make it difficult or impossible to
obtain a reliable market quotation; and a security whose price, as provided by
the third-party pricing service, does not reflect the security's fair value. As
a general principle, the current fair value of a security would appear to be the
amount which the owner might reasonably expect to receive for the security upon
its current sale. When fair value prices are used, generally they will differ
from market quotations or official closing prices on the applicable exchanges. A
variety of factors may be considered in determining the fair value of such
securities, including, but not limited to, the following:

            1)    the fundamental business data relating to the issuer;

            2)    an evaluation of the forces which influence the market in
                  which these securities are purchased and sold;

            3)    the type, size and cost of a security;

            4)    the financial statements of the issuer;

            5)    the credit quality and cash flow of the issuer, based on the
                  Advisor's or external analysis;

            6)    the information as to any transactions in or offers for the
                  security;

            7)    the price and extent of public trading in similar securities
                  of the issuer/borrower, or comparable companies;

            8)    the coupon payments;

            9)    the quality, value and salability of collateral, if any,
                  securing the security;

           10)    the business prospects of the issuer, including any ability to
                  obtain money or resources from a parent or affiliate and an
                  assessment of the issuer's management (for corporate debt
                  only);

           11)    the prospects for the issuer's industry, and multiples (of
                  earnings and/or cash flows) being paid for similar businesses
                  in that industry (for corporate debt only); and

           12)    other relevant factors.

The Fund is subject to fair value accounting standards that define fair value,
establish the framework for measuring fair value and provide a three-level
hierarchy for fair valuation based upon the inputs to the valuation as of the
measurement date. The three levels of the fair value hierarchy are as follows:

      o     Level 1 - Level 1 inputs are quoted prices in active markets for
            identical investments. An active market is a market in which
            transactions for the investment occur with sufficient frequency and
            volume to provide pricing information on an ongoing basis.

      o     Level 2 - Level 2 inputs are observable inputs, either directly or
            indirectly, and include the following:

            o     Quoted prices for similar investments in active markets.

            o     Quoted prices for identical or similar investments in markets
                  that are non-active. A non-active market is a market where
                  there are few transactions for the investment, the prices are
                  not current, or price quotations vary substantially either
                  over time or among market makers, or in which little
                  information is released publicly.

            o     Inputs other than quoted prices that are observable for the
                  investment (for example, interest rates and yield curves
                  observable at commonly quoted intervals, volatilities,
                  prepayment speeds, loss severities, credit risks, and default
                  rates).

            o     Inputs that are derived principally from or corroborated by
                  observable market data by correlation or other means.

      o     Level 3 - Level 3 inputs are unobservable inputs. Unobservable
            inputs may reflect the reporting entity's own assumptions about the
            assumptions that market participants would use in pricing the
            investment.

The inputs or methodologies used for valuing investments are not necessarily an
indication of the risk associated with investing in those investments. A summary
of the inputs used to value the Fund's investments as of April 30, 2022, is
included with the Fund's Portfolio of Investments.

B. SECURITIES TRANSACTIONS AND INVESTMENT INCOME

Securities transactions are recorded as of the trade date. Realized gains and
losses from securities transactions are recorded on the identified cost basis.
Dividend income is recorded on the ex-dividend date. Interest income is recorded
daily on the accrual basis. Amortization of premiums and accretion of discounts
are recorded using the effective interest method.

The United Kingdom's Financial Conduct Authority (the "FCA"), which regulates
the London Interbank Offered Rates ("LIBOR") announced on March 5, 2021 that it
intended to phase-out all LIBOR reference rates, beginning December 31, 2021.
Since that announcement, the FCA has ceased publication of all non-USD LIBOR
reference rates and the 1-week and 2-month USD LIBOR reference rates as of
December 31, 2021. The remaining USD LIBOR settings will cease to be published
or no longer be representative immediately after June 30, 2023. The
International Swaps and Derivatives Association, Inc. ("ISDA") confirmed that
the FCA's March 5, 2021 announcement of its intention to cease providing LIBOR
reference rates, constituted an index cessation event under the Interbank
Offered Rates ("IBOR") Fallbacks Supplement and the ISDA 2020 IBOR Fallbacks
Protocol for all 35 LIBOR settings and confirmed that the spread adjustment to
be used in ISDA fallbacks was fixed as of the date of the announcement.


Page 48





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NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

In the United States, the Alternative Reference Rates Committee (the "ARRC"), a
group of market participants convened by the Board of Governors of the Federal
Reserve System and the Federal Reserve Bank of New York in cooperation with
other federal and state government agencies, has since 2014 undertaken efforts
to identify U.S. dollar reference interest rates as alternatives to LIBOR and to
facilitate the mitigation of LIBOR-related risks. In June 2017, the ARRC
identified the Secured Overnight Financing Rate ("SOFR"), a broad measure of the
cost of cash overnight borrowing collateralized by U.S. Treasury securities, as
the preferred alternative for U.S. dollar LIBOR. The Federal Reserve Bank of New
York began daily publishing of SOFR in April 2018. There is no assurance that
any alternative reference rate, including SOFR, will be similar to or produce
the same value or economic equivalence as LIBOR or that instruments using an
alternative rate will have the same volume or liquidity.

At this time, it is not possible to predict the full impact of the elimination
of LIBOR and the establishment of an alternative reference rate on the Fund or
its investments.

The Fund invests in interest-only securities. For these securities, if there is
a change in the estimated cash flows, based on an evaluation of current
information, then the estimated yield is adjusted. Additionally, if the
evaluation of current information indicates a permanent impairment of the
security, the cost basis of the security is written down and a loss is
recognized. Debt obligations may be placed on non-accrual status and the related
interest income may be reduced by ceasing current accruals and writing off
interest receivables when the collection of all or a portion of interest has
become doubtful based on consistently applied procedures. A debt obligation is
removed from non-accrual status when the issuer resumes interest payments or
when collectability of interest is reasonably assured.

Securities purchased or sold on a when-issued, delayed-delivery or forward
purchase commitment basis may have extended settlement periods. The value of the
security so purchased is subject to market fluctuations during this period. The
Fund maintains liquid assets with a current value at least equal to the amount
of its when-issued, delayed-delivery or forward purchase commitments until
payment is made. At April 30, 2022, the Fund held $38,171,246 when-issued or
delayed-delivery securities. At April 30, 2022, the Fund held $1,034,904,160 of
forward purchase commitments.

C. SHORT SALES

Short sales are utilized to manage interest rate and spread risk, and are
transactions in which securities or other instruments (such as options,
forwards, futures or other derivative contracts) are sold that are not currently
owned in the Fund's portfolio. When the Fund engages in a short sale, the Fund
must borrow the security sold short and deliver the security to the
counterparty. Short selling allows the Fund to profit from a decline in a market
price to the extent such decline exceeds the transaction costs and the costs of
borrowing the securities. The Fund is charged a fee or premium to borrow the
securities sold short and is obligated to repay the lenders of the securities.
Any dividends or interest that accrues on the securities during the period of
the loan are due to the lenders. A gain, limited to the price at which the
security was sold short, or a loss, unlimited in size, will be recognized upon
the termination of the short sale; which is effected by the Fund purchasing the
security sold short and delivering the security to the lender. Any such gain or
loss may be offset, completely or in part, by the change in the value of the
long portion of the Fund's portfolio. The Fund is subject to the risk it may be
unable to reacquire a security to terminate a short position except at a price
substantially in excess of the last quoted price. Also, there is the risk that
the counterparty to a short sale may fail to honor its contractual terms,
causing a loss to the Fund.

D. FUTURES CONTRACTS

The Fund may purchase or sell (i.e., is long or short) exchange-listed futures
contracts to hedge against or gain exposure to changes in interest rates
(interest rate risk). Futures contracts are agreements between the Fund and a
counterparty to buy or sell a specific quantity of an underlying instrument at a
specified price and at a specified date. Depending on the terms of the contract,
futures contracts are settled either through physical delivery of the underlying
instrument on the settlement date or by payment of a cash settlement amount on
the settlement date. Open futures contracts can also be closed out prior to
settlement by entering into an offsetting transaction in a matching futures
contract. If the Fund is not able to enter into an offsetting transaction, the
Fund will continue to be required to maintain margin deposits on the futures
contract. When the contract is closed or expires, the Fund records a realized
gain or loss equal to the difference between the value of the contract at the
time it was opened and the value at the time it was closed or expired. This gain
or loss is included in "Net realized gain (loss) on futures contracts" on the
Statement of Operations.

Upon entering into a futures contract, the Fund must deposit funds, called
margin, with its custodian in the name of the clearing broker equal to a
specified percentage of the current value of the contract. Open futures
contracts are marked-to-market daily with the change in value recognized as a
component of "Net change in unrealized appreciation (depreciation) on futures
contracts" on the Statement of Operations. Pursuant to the contract, the Fund
agrees to receive from or pay to the broker an amount of cash equal to the daily
fluctuation in value of the contract. Such receipts or payments are known as
variation margin and are included in "Variation margin" receivable or payable


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NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

on the Statement of Assets and Liabilities. If market conditions change
unexpectedly, the Fund may not achieve the anticipated benefits of the futures
contract and may realize a loss. The use of futures contracts involves the risk
of imperfect correlation in movements in the price of the futures contracts,
interest rates and the underlying instruments.

E. OPTIONS CONTRACTS

The Fund may invest in exchange-listed options on U.S. Treasury securities,
exchange-listed options on U.S. Treasury futures contracts and exchange-listed
U.S. Treasury futures contracts. The Fund may also invest up to 20% of its net
assets in over-the-counter derivatives. The Fund uses derivative instruments
primarily to hedge interest rate risk and actively manage interest rate
exposure. The primary risk exposure is interest rate risk.

The Fund may purchase (buy) or write (sell) put and call options on futures
contracts and enter into closing transactions with respect to such options to
terminate an existing position. A futures option gives the holder the right, in
return for the premium paid, to assume a long position (call) or short position
(put) in a futures contract at a specified exercise price prior to the
expiration of the option. Upon exercise of a call option, the holder acquires a
long position in the futures contract and the writer is assigned the opposite
short position. In the case of a put option, the opposite is true. Prior to
exercise or expiration, a futures option contract may be closed out by an
offsetting purchase or sale of a futures option of the same series. When the
Fund writes (sells) an option, an amount equal to the premium received by the
Fund is included in "Options contracts written, at value" on the Statement of
Assets and Liabilities. When the Fund purchases (buys) an option, the premium
paid represents the cost of the option, which is included in "Premiums paid on
options contracts purchased" on the Statement of Assets and Liabilities. Options
are marked-to-market daily and their value is affected by changes in the value
of the underlying security, changes in interest rates, changes in the actual or
perceived volatility of the securities markets and the underlying securities,
and the remaining time to the option's expiration. The value of options may also
be adversely affected if the market for the options becomes less liquid or the
trading volume diminishes.

The Fund uses options on futures contracts in connection with hedging
strategies. Generally, these strategies are applied under the same market and
market sector conditions in which the Fund uses put and call options on
securities. The purchase of put options on futures contracts is analogous to the
purchase of puts on securities so as to hedge the Fund's securities holdings
against the risk of declining market prices. The writing of a call option or the
purchasing of a put option on a futures contract constitutes a partial hedge
against declining prices of securities which are deliverable upon exercise of
the futures contract. If the price at expiration of a written call option is
below the exercise price, the Fund will retain the full amount of the option
premium which provides a partial hedge against any decline that may have
occurred in the Fund's holdings of securities. If the price when the option is
exercised is above the exercise price, however, the Fund will incur a loss,
which may be offset, in whole or in part, by the increase in the value of the
securities held by the Fund that were being hedged. Writing a put option or
purchasing a call option on a futures contract serves as a partial hedge against
an increase in the value of the securities the Fund intends to acquire. Realized
gains and losses on written options are included in "Net realized gain (loss) on
written options contracts" on the Statement of Operations. Realized gains and
losses on purchased options are included in "Net realized gain (loss) on
purchased options contracts" on the Statement of Operations.

The Fund is required to deposit and maintain margin with respect to put and call
options on futures contracts written by it. Such margin deposits will vary
depending on the nature of the underlying futures contract (and the related
initial margin requirements), the current market value of the option and other
futures positions held by the Fund. The Fund will pledge in a segregated account
at the Fund's custodian, liquid assets, such as cash, U.S. government securities
or other high-grade liquid debt obligations equal in value to the amount due on
the underlying obligation. Such segregated assets will be marked-to-market
daily, and additional assets will be pledged in the segregated account whenever
the total value of the pledged assets falls below the amount due on the
underlying obligation.

The risks associated with the use of options on future contracts include the
risk that the Fund may close out its position as a writer of an option only if a
liquid secondary market exists for such options, which cannot be assured. The
Fund's successful use of options on futures contracts depends on the Advisor's
ability to correctly predict the movement in prices on futures contracts and the
underlying instruments, which may prove to be incorrect. In addition, there may
be imperfect correlation between the instruments being hedged and the futures
contract subject to option.

F. INTEREST-ONLY SECURITIES

An interest-only security ("IO Security") is the interest-only portion of a
mortgage-backed security that receives some or all of the interest portion of
the underlying mortgage-backed security and little or no principal. A reference
principal value called a notional value is used to calculate the amount of
interest due to the IO Security. IO Securities are sold at a deep discount to
their notional principal amount. Generally speaking, when interest rates are
falling and prepayment rates are increasing, the value of an IO Security will
fall. Conversely, when interest rates are rising and prepayment rates are
decreasing, generally the value of an IO Security will rise. These securities,
if any, are identified on the Portfolio of Investments.


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NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

G. PRINCIPAL-ONLY SECURITIES

A principal-only security ("PO Security") is the principal-only portion of a
mortgage-backed security that does not receive any interest, is priced at a deep
discount to its redemption value and ultimately receives the redemption value.
Generally speaking, when interest rates are falling and prepayment rates are
increasing, the value of a PO Security will rise. Conversely, when interest
rates are rising and prepayment rates are decreasing, generally the value of a
PO Security will fall. These securities, if any, are identified on the Portfolio
of Investments.

H. STRIPPED MORTGAGE-BACKED SECURITIES

Stripped mortgage-backed securities are created by segregating the cash flows
from underlying mortgage loans or mortgage securities to create two or more new
securities, each with a specified percentage of the underlying security's
principal or interest payments. Mortgage-backed securities may be partially
stripped so that each investor class receives some interest and some principal.
When securities are completely stripped, however, all of the interest is
distributed to holders of one type of security known as an IO Security and all
of the principal is distributed to holders of another type of security known as
a PO Security. These securities, if any, are identified on the Portfolio of
Investments.

I. MORTGAGE DOLLAR ROLLS AND TBA TRANSACTIONS

The Fund may invest, without limitation, in mortgage dollar rolls. The Fund
intends to enter into mortgage dollar rolls only with high quality securities
dealers and banks, as determined by the Fund's investment advisor. In a mortgage
dollar roll, the Fund will sell (or buy) mortgage-backed securities for delivery
on a specified date and simultaneously contract to repurchase (or sell)
substantially similar (same type, coupon and maturity) securities on a future
date. Mortgage dollar rolls are recorded as separate purchases and sales in the
Fund. The Fund may also invest in TBA Transactions. A TBA Transaction is a
method of trading mortgage-backed securities. TBA Transactions generally are
conducted in accordance with widely-accepted guidelines which establish commonly
observed terms and conditions for execution, settlement and delivery. In a TBA
Transaction, the buyer and the seller agree on general trade parameters such as
agency, settlement date, par amount and price.

J. AFFILIATED TRANSACTIONS

The Fund invests in securities of affiliated funds. Dividend income and realized
gains and losses, and change in appreciation (depreciation) from affiliated
funds are presented on the Statement of Operations. The Fund's investment
performance and risks are directly related to the investment performance and
risks of the affiliated funds.

Amounts related to these investments at April 30, 2022 and for the six months
then ended are as follows:



                                                                              CHANGES IN
                                                                              UNREALIZED      REALIZED
                           SHARES AT   VALUE AT                              APPRECIATION       GAIN        VALUE AT      DIVIDEND
      SECURITY NAME        4/30/2022  10/31/2021   PURCHASES      SALES     (DEPRECIATION)     (LOSS)      4/30/2022       INCOME
------------------------------------------------------------------------------------------------------------------------------------
                                                                                                
First Trust Long Duration
   Opportunities ETF          29,359  $  813,538  $         --  $       --  $      (97,178) $         --  $    716,360  $      5,983


K. DIVIDENDS AND DISTRIBUTION TO SHAREHOLDERS

Dividends from net investment income, if any, are declared and paid monthly by
the Fund, or as the Board of Trustees may determine from time to time.
Distributions of net realized gains earned by the Fund, if any, are distributed
at least annually.

Distributions in cash may be reinvested automatically in additional whole shares
only if the broker through whom the shares were purchased makes such option
available. Such shares will generally be reinvested by the broker based upon the
market price of those shares and investors may be subject to customary brokerage
commissions charged by the broker.

Distributions from net investment income and realized capital gains are
determined in accordance with federal income tax regulations, which may differ
from U.S. GAAP. Certain capital accounts in the financial statements are
periodically adjusted for permanent differences in order to reflect their tax
character. These permanent differences are primarily due to the varying
treatment of income and gain/loss on portfolio securities held by the Fund and
have no impact on net assets or NAV per share. Temporary differences, which
arise from recognizing certain items of income, expense and gain/loss in
different periods for financial statement and tax purposes, will reverse at some
time in the future.


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--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
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               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

The tax character of distributions paid during the fiscal year ended October 31,
2021 was as follows:

Distributions paid from:
Ordinary income.................................   $   48,718,452
Capital gains...................................               --
Return of capital...............................       90,717,550

As of October 31, 2021, the components of distributable earnings on a tax basis
for the Fund were as follows:

Undistributed ordinary income...................   $  (10,258,184)
Accumulated capital and other gain (loss).......      (72,543,076)
Net unrealized appreciation (depreciation)......       26,903,240

L. INCOME TAXES

The Fund intends to continue to qualify as a regulated investment company by
complying with the requirements under Subchapter M of the Internal Revenue Code
of 1986, as amended, which includes distributing substantially all of its net
investment income and net realized gains to shareholders. Accordingly, no
provision has been made for federal and state income taxes. However, due to the
timing and amount of distributions, the Fund may be subject to an excise tax of
4% of the amount by which approximately 98% of the Fund's taxable income exceeds
the distributions from such taxable income for the calendar year.

The Fund is subject to accounting standards that establish a minimum threshold
for recognizing, and a system for measuring, the benefits of a tax position
taken or expected to be taken in a tax return. The taxable years ended 2018,
2019, 2020, and 2021 remain open to federal and state audit. As of April 30,
2022, management has evaluated the application of these standards to the Fund
and has determined that no provision for income tax is required in the Fund's
financial statements for uncertain tax positions.

The Fund intends to utilize provisions of the federal income tax laws, which
allow it to carry a realized capital loss forward indefinitely following the
year of the loss and offset such loss against any future realized capital gains.
The Fund is subject to certain limitations under U.S. tax rules on the use of
capital loss carryforwards and net unrealized built-in losses. These limitations
apply when there has been a 50% change in ownership. At October 31, 2021, the
Fund had non-expiring capital loss carryforwards available for federal income
tax purposes of $72,543,076.

During the taxable year ended October 31, 2021, the Fund utilized non-expiring
capital loss carryforwards in the amount of $36,399,411.

Certain losses realized during the current fiscal year may be deferred and
treated as occurring on the first day of the following fiscal year for federal
income tax purposes. For the fiscal year ended October 31, 2021, the Fund had no
net late year ordinary or capital losses.

As of April 30, 2022, the aggregate cost, gross unrealized appreciation, gross
unrealized depreciation, and net unrealized appreciation/(depreciation) on
investments (including short positions and derivatives, if any) for federal
income tax purposes were as follows:



                                  Gross              Gross          Net Unrealized
                                Unrealized         Unrealized        Appreciation
              Tax Cost         Appreciation      (Depreciation)     (Depreciation)
          ----------------   ----------------   ----------------   ----------------
                                                       
          $  5,205,937,101   $    105,974,609   $   (262,193,009)  $   (156,218,400)


M. EXPENSES

Expenses, other than the investment advisory fee and other excluded expenses,
are paid by the Advisor (see Note 3).

3. INVESTMENT ADVISORY FEE, AFFILIATED TRANSACTIONS AND OTHER FEE ARRANGEMENTS

First Trust, the investment advisor to the Fund, is a limited partnership with
one limited partner, Grace Partners of DuPage L.P., and one general partner, The
Charger Corporation. The Charger Corporation is an Illinois corporation
controlled by James A. Bowen, Chief Executive Officer of First Trust. First
Trust is responsible for the selection and ongoing monitoring of the securities
in the Fund's portfolio, managing the Fund's business affairs and providing
certain administrative services necessary for the management of the Fund.


Page 52





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NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

Pursuant to the Investment Management Agreement between the Trust and the
Advisor, First Trust manages the investment of the Fund's assets and is
responsible for the Fund's expenses, including the cost of transfer agency,
custody, fund administration, legal, audit and other services, but excluding fee
payments under the Investment Management Agreement, interest, taxes, pro rata
share of fees and expenses attributable to investments in other investment
companies ("acquired fund fees and expenses"), brokerage commissions and other
expenses connected with the execution of portfolio transactions, distribution
and service fees payable pursuant to a Rule 12b-1 plan, if any, and
extraordinary expenses. The Fund has agreed to pay First Trust an annual unitary
management fee equal to 0.65% of its average daily net assets. In addition, the
Fund incurs acquired fund fees and expenses. The total of the unitary management
fee and acquired fund fees and expenses represents the Fund's total annual
operating expenses.

The Trust has multiple service agreements with The Bank of New York Mellon
("BNYM"). Under the service agreements, BNYM performs custodial, fund
accounting, certain administrative services, and transfer agency services for
the Fund. As custodian, BNYM is responsible for custody of the Fund's assets. As
fund accountant and administrator, BNYM is responsible for maintaining the books
and records of the Fund's securities and cash. As transfer agent, BNYM is
responsible for maintaining shareholder records for the Fund. BNYM is a
subsidiary of The Bank of New York Mellon Corporation, a financial holding
company. Each Trustee who is not an officer or employee of First Trust, any
sub-advisor or any of their affiliates ("Independent Trustees") is paid a fixed
annual retainer that is allocated equally among each fund in the First Trust
Fund Complex. Each Independent Trustee is also paid an annual per fund fee that
varies based on whether the fund is a closed-end or other actively managed fund,
a defined-outcome fund or an index fund.

Additionally, the Lead Independent Trustee and the Chairs of the Audit
Committee, Nominating and Governance Committee and Valuation Committee are paid
annual fees to serve in such capacities, with such compensation allocated pro
rata among each fund in the First Trust Fund Complex based on net assets.
Independent Trustees are reimbursed for travel and out-of-pocket expenses in
connection with all meetings. The Lead Independent Trustee and Committee Chairs
will rotate every three years. The officers and "Interested" Trustee receive no
compensation from the Trust for acting in such capacities.

                      4. PURCHASES AND SALES OF SECURITIES

The cost of purchases of U.S. Government securities and non-U.S. Government
securities, excluding investments sold short and short-term investments, for the
six months ended April 30, 2022, were $14,551,541,304 and $542,206,291,
respectively. The proceeds from sales and paydowns of U.S. Government securities
and non-U.S. Government securities, excluding investments sold short and
short-term investments, for the six months ended April 30, 2022, were
$14,850,049,237 and $304,997,134, respectively. The cost of purchases to cover
investments sold short and the proceeds of investments sold short were
$10,623,256,992 and $11,315,839,191, respectively.

For the six months ended April 30, 2022, the Fund had no in-kind transactions.

                           5. DERIVATIVE TRANSACTIONS

The following table presents the types of derivatives held by the Fund at April
30, 2022, the primary underlying risk exposure and the location of these
instruments as presented on the Statement of Assets and Liabilities.



                                      ASSET DERIVATIVES                        LIABILITY DERIVATIVES
                          -----------------------------------------   ---------------------------------------
DERIVATIVE    RISK          STATEMENT OF ASSETS AND                    STATEMENT OF ASSETS AND
INSTRUMENTS   EXPOSURE        LIABILITIES LOCATION         VALUE         LIABILITIES LOCATION        VALUE
-----------   ---------   ----------------------------  -----------   --------------------------  -----------
                                                                                   
Futures       Interest    Unrealized appreciation on                  Unrealized depreciation on
              rate risk   futures contracts*            $62,487,542   futures contracts*          $    16,308

Options       Interest    Options contracts purchased,                Options contracts written,
              rate risk   at value                          893,750   at value                        685,547


* Includes cumulative appreciation/depreciation on futures contracts as reported
in the Portfolio of Investments. Only the current day's variation margin is
presented on the Statement of Assets and Liabilities.


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--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

The following table presents the amount of net realized gain (loss) and change
in net unrealized appreciation (depreciation) recognized for the six months
ended April 30, 2022, on derivative instruments, as well as the primary
underlying risk exposure associated with the instruments.



STATEMENT OF OPERATIONS LOCATION                              INTEREST RATE RISK
----------------------------------------------------------------------------------
                                                             
Net realized gain (loss) on:
   Futures contracts                                            $     80,199,556
   Purchased options contracts                                        (1,165,816)
   Written options contracts                                           7,195,714
Net change in unrealized appreciation (depreciation) on:
   Futures contracts                                                  48,023,510
   Purchased options contracts                                           587,108
   Written options contracts                                             792,889


For the six months ended April 30, 2022, the notional value of futures contracts
opened and closed were $10,636,680,448 and $10,631,212,892, respectively.

During the six months ended April 30, 2022, the premiums for purchased options
contracts opened were $1,500,447 and the premiums for purchased options
contracts closed, exercised and expired were $1,193,805.

During the six months ended April 30, 2022, the premiums for written options
contracts opened were $10,440,444 and the premiums for written options contracts
closed, exercised and expired were $14,050,516.

The Fund does not have the right to offset financial assets and financial
liabilities related to futures and options contracts on the Statement of Assets
and Liabilities.

                 6. CREATIONS, REDEMPTIONS AND TRANSACTION FEES

The Fund generally issues and redeems its shares in primary market transactions
through a creation and redemption mechanism and does not sell or redeem
individual shares. Instead, financial entities known as "Authorized
Participants" have contractual arrangements with the Fund or one of the Fund's
service providers to purchase and redeem Fund shares directly with the Fund in
large blocks of shares known as "Creation Units." Prior to the start of trading
on every business day, the Fund publishes through the National Securities
Clearing Corporation ("NSCC") the "basket" of securities, cash or other assets
that it will accept in exchange for a Creation Unit of the Fund's shares. An
Authorized Participant that wishes to effectuate a creation of the Fund's shares
deposits with the Fund the "basket" of securities, cash or other assets
identified by the Fund that day, and then receives the Creation Unit of the
Fund's shares in return for those assets. After purchasing a Creation Unit, the
Authorized Participant may continue to hold the Fund's shares or sell them in
the secondary market. The redemption process is the reverse of the purchase
process: the Authorized Participant redeems a Creation Unit of the Fund's shares
for a basket of securities, cash or other assets. The combination of the
creation and redemption process with secondary market trading in the Fund's
shares and underlying securities provides arbitrage opportunities that are
designed to help keep the market price of the Fund's shares at or close to the
NAV per share of the Fund.

The Fund imposes fees in connection with the purchase of Creation Units. These
fees may vary based upon various fact-based circumstances, including, but not
limited to, the composition of the securities included in the Creation Unit or
the countries in which the transactions are settled. The price for each Creation
Unit will equal the daily NAV per share of the Fund times the number of shares
in a Creation Unit, plus the fees described above and, if applicable, any
operational processing and brokerage costs, transfer fees, stamp taxes and part
or all of the spread between the expected bid and offer side of the market
related to the securities comprising the creation basket.

The Fund also imposes fees in connection with the redemption of Creation Units.
These fees may vary based upon various fact-based circumstances, including, but
not limited to, the composition of the securities included in the Creation Unit
or the countries in which the transactions are settled. The price received for
each Creation Unit will equal the daily NAV per share of the Fund times the
number of shares in a Creation Unit, minus the fees described above and, if
applicable, any operational processing and brokerage costs, transfer fees, stamp
taxes and part or all of the spread between the expected bid and offer side of
the market related to the securities comprising the redemption basket. Investors
who use the services of a broker or other such intermediary in addition to an
Authorized Participant to effect a redemption of a Creation Unit may also be
assessed an amount to cover the cost of such services. The redemption fee
charged by the Fund will comply with Rule 22c-2 of the 1940 Act which limits
redemption fees to no more than 2% of the value of the shares redeemed.


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--------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONTINUED)
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

                              7. DISTRIBUTION PLAN

The Board of Trustees adopted a Distribution and Service Plan pursuant to Rule
12b-1 under the 1940 Act. In accordance with the Rule 12b-1 plan, the Fund is
authorized to pay an amount up to 0.25% of its average daily net assets each
year to reimburse First Trust Portfolios L.P. ("FTP"), the distributor of the
Fund, for amounts expended to finance activities primarily intended to result in
the sale of Creation Units or the provision of investor services. FTP may also
use this amount to compensate securities dealers or other persons that are
Authorized Participants for providing distribution assistance, including
broker-dealer and shareholder support and educational and promotional services.

No 12b-1 fees are currently paid by the Fund, and pursuant to a contractual
arrangement, no 12b-1 fees will be paid any time before March 31, 2023.

                               8. INDEMNIFICATION

The Trust, on behalf of the Fund, has a variety of indemnification obligations
under contracts with its service providers. The Trust's maximum exposure under
these arrangements is unknown. However, the Trust has not had prior claims or
losses pursuant to these contracts and expects the risk of loss to be remote.

                              9. SUBSEQUENT EVENTS

Management has evaluated the impact of all subsequent events on the Fund through
the date the financial statements were issued, and has determined that there
were no subsequent events requiring recognition or disclosure in the financial
statements that have not already been disclosed.


                                                                         Page 55





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ADDITIONAL INFORMATION
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

                      PROXY VOTING POLICIES AND PROCEDURES

A description of the policies and procedures that the Trust uses to determine
how to vote proxies and information on how the Fund voted proxies relating to
its portfolio securities during the most recent 12-month period ended June 30 is
available (1) without charge, upon request, by calling (800) 988-5891; (2) on
the Fund's website at www.ftportfolios.com; and (3) on the Securities and
Exchange Commission's ("SEC") website at www.sec.gov.

                               PORTFOLIO HOLDINGS

The Fund files portfolio holdings information for each month in a fiscal quarter
within 60 days after the end of the relevant fiscal quarter on Form N-PORT.
Portfolio holdings information for the third month of each fiscal quarter will
be publicly available on the SEC's website at www.sec.gov. The Fund's complete
schedule of portfolio holdings for the second and fourth quarters of each fiscal
year is included in the semi-annual and annual reports to shareholders,
respectively, and is filed with the SEC on Form N-CSR. The semi-annual and
annual report for the Fund is available to investors within 60 days after the
period to which it relates. The Fund's Forms N-PORT and Forms N-CSR are
available on the SEC's website listed above.

                              RISK CONSIDERATIONS

RISKS ARE INHERENT IN ALL INVESTING. CERTAIN GENERAL RISKS THAT MAY BE
APPLICABLE TO A FUND ARE IDENTIFIED BELOW, BUT NOT ALL OF THE MATERIAL RISKS
RELEVANT TO EACH FUND ARE INCLUDED IN THIS REPORT AND NOT ALL OF THE RISKS BELOW
APPLY TO EACH FUND. THE MATERIAL RISKS OF INVESTING IN EACH FUND ARE SPELLED OUT
IN ITS PROSPECTUS, STATEMENT OF ADDITIONAL INFORMATION AND OTHER REGULATORY
FILINGS. BEFORE INVESTING, YOU SHOULD CONSIDER EACH FUND'S INVESTMENT OBJECTIVE,
RISKS, CHARGES AND EXPENSES, AND READ EACH FUND'S PROSPECTUS AND STATEMENT OF
ADDITIONAL INFORMATION CAREFULLY. YOU CAN DOWNLOAD EACH FUND'S PROSPECTUS AT
WWW.FTPORTFOLIOS.COM OR CONTACT FIRST TRUST PORTFOLIOS L.P. AT (800) 621-1675 TO
REQUEST A PROSPECTUS, WHICH CONTAINS THIS AND OTHER INFORMATION ABOUT EACH FUND.

CONCENTRATION RISK. To the extent that a fund is able to invest a significant
percentage of its assets in a single asset class or the securities of issuers
within the same country, state, region, industry or sector, an adverse economic,
business or political development may affect the value of the fund's investments
more than if the fund were more broadly diversified. A fund that tracks an index
will be concentrated to the extent the fund's corresponding index is
concentrated. A concentration makes a fund more susceptible to any single
occurrence and may subject the fund to greater market risk than a fund that is
more broadly diversified.

CREDIT RISK. Credit risk is the risk that an issuer of a security will be unable
or unwilling to make dividend, interest and/or principal payments when due and
the related risk that the value of a security may decline because of concerns
about the issuer's ability to make such payments.

CYBER SECURITY RISK. The funds are susceptible to potential operational risks
through breaches in cyber security. A breach in cyber security refers to both
intentional and unintentional events that may cause a fund to lose proprietary
information, suffer data corruption or lose operational capacity. Such events
could cause a fund to incur regulatory penalties, reputational damage,
additional compliance costs associated with corrective measures and/or financial
loss. In addition, cyber security breaches of a fund's third-party service
providers, such as its administrator, transfer agent, custodian, or sub-advisor,
as applicable, or issuers in which the fund invests, can also subject a fund to
many of the same risks associated with direct cyber security breaches.

DEFINED OUTCOME FUNDS RISK. To the extent a fund's investment strategy is
designed to deliver returns tied to the price performance of an underlying ETF,
an investor may not realize the returns the fund seeks to achieve if that
investor does not hold shares for the entire target outcome period. In the event
an investor purchases shares after the first day of the target outcome period or
sells shares prior to the end of the target outcome period, the buffer that the
fund seeks to provide against a decline in the value of the underlying ETF may
not be available, the enhanced returns that the fund seeks to provide (if any)
may not be available and the investor may not participate in a gain in the value
of the underlying ETF up to the cap for the investor's investment period.
Additionally, the fund will not participate in gains of the underlying ETF above
the cap and a shareholder may lose their entire investment. If the fund seeks
enhanced returns, there are certain time periods when the value of the fund may
fall faster than the value of the underlying ETF, and it is very unlikely that,
on any given day during which the underlying ETF share price increases in value,
the fund's share price will increase at the same rate as the enhanced returns
sought by the fund, which is designed for an entire target outcome period.
Trading flexible exchange options involves risks different from, or possibly
greater than, the risks associated with investing directly in securities, such
as less liquidity and correlation and valuation risks. A fund may experience
substantial downside from specific flexible exchange option positions and
certain positions may expire worthless.


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--------------------------------------------------------------------------------
ADDITIONAL INFORMATION (CONTINUED)
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

DERIVATIVES RISK. To the extent a fund uses derivative instruments such as
futures contracts, options contracts and swaps, the fund may experience losses
because of adverse movements in the price or value of the underlying asset,
index or rate, which may be magnified by certain features of the derivative.
These risks are heightened when a fund's portfolio managers use derivatives to
enhance the fund's return or as a substitute for a position or security, rather
than solely to hedge (or offset) the risk of a position or security held by the
fund.

EQUITY SECURITIES RISK. To the extent a fund invests in equity securities, the
value of the fund's shares will fluctuate with changes in the value of the
equity securities. Equity securities prices fluctuate for several reasons,
including changes in investors' perceptions of the financial condition of an
issuer or the general condition of the relevant stock market, such as market
volatility, or when political or economic events affecting the issuers occur. In
addition, common stock prices may be particularly sensitive to rising interest
rates, as the cost of capital rises and borrowing costs increase. Equity
securities may decline significantly in price over short or extended periods of
time, and such declines may occur in the equity market as a whole, or they may
occur in only a particular country, company, industry or sector of the market.

ETF RISK. The shares of an ETF trade like common stock and represent an interest
in a portfolio of securities. The risks of owning an ETF generally reflect the
risks of owning the underlying securities, although lack of liquidity in an ETF
could result in it being more volatile and ETFs have management fees that
increase their costs. Shares of an ETF trade on an exchange at market prices
rather than net asset value, which may cause the shares to trade at a price
greater than net asset value (premium) or less than net asset value (discount).
In times of market stress, decisions by market makers to reduce or step away
from their role of providing a market for an ETF's shares, or decisions by an
ETF's authorized participants that they are unable or unwilling to proceed with
creation and/or redemption orders of an ETF's shares, could result in shares of
the ETF trading at a discount to net asset value and in greater than normal
intraday bid-ask spreads.

FIXED INCOME SECURITIES RISK. To the extent a fund invests in fixed income
securities, the fund will be subject to credit risk, income risk, interest rate
risk, liquidity risk and prepayment risk. Income risk is the risk that income
from a fund's fixed income investments could decline during periods of falling
interest rates. Interest rate risk is the risk that the value of a fund's fixed
income securities will decline because of rising interest rates. Liquidity risk
is the risk that a security cannot be purchased or sold at the time desired, or
cannot be purchased or sold without adversely affecting the price. Prepayment
risk is the risk that the securities will be redeemed or prepaid by the issuer,
resulting in lower interest payments received by the fund. In addition to these
risks, high yield securities, or "junk" bonds, are subject to greater market
fluctuations and risk of loss than securities with higher ratings, and the
market for high yield securities is generally smaller and less liquid than that
for investment grade securities.

INDEX OR MODEL CONSTITUENT RISK. Certain funds may be a constituent of one or
more indices or ETF models. As a result, such a fund may be included in one or
more index-tracking exchange-traded funds or mutual funds. Being a component
security of such a vehicle could greatly affect the trading activity involving a
fund, the size of the fund and the market volatility of the fund. Inclusion in
an index could increase demand for the fund and removal from an index could
result in outsized selling activity in a relatively short period of time. As a
result, a fund's net asset value could be negatively impacted and the fund's
market price may be significantly below its net asset value during certain
periods. In addition, index rebalances may potentially result in increased
trading activity in a fund's shares.

INDEX PROVIDER RISK. To the extent a fund seeks to track an index, it is subject
to Index Provider Risk. There is no assurance that the Index Provider will
compile the Index accurately, or that the Index will be determined, maintained,
constructed, reconstituted, rebalanced, composed, calculated or disseminated
accurately. To correct any such error, the Index Provider may carry out an
unscheduled rebalance or other modification of the Index constituents or
weightings, which may increase the fund's costs. The Index Provider does not
provide any representation or warranty in relation to the quality, accuracy or
completeness of data in the Index, and it does not guarantee that the Index will
be calculated in accordance with its stated methodology. Losses or costs
associated with any Index Provider errors generally will be borne by the fund
and its shareholders.

INVESTMENT COMPANIES RISK. To the extent a fund invests in the securities of
other investment vehicles, the fund will incur additional fees and expenses that
would not be present in a direct investment in those investment vehicles.
Furthermore, the fund's investment performance and risks are directly related to
the investment performance and risks of the investment vehicles in which the
fund invests.

LIBOR RISK. To the extent a fund invests in floating or variable rate
obligations that use the London Interbank Offered Rate ("LIBOR") as a reference
interest rate, it is subject to LIBOR Risk. The United Kingdom's Financial
Conduct Authority, which regulates LIBOR, has ceased making LIBOR available as a
reference rate over a phase-out period that began December 31, 2021. There is no
assurance that any alternative reference rate, including the Secured Overnight
Financing Rate ("SOFR") will be similar to or produce the same value or economic
equivalence as LIBOR or that instruments using an alternative rate will have the
same volume or liquidity. The unavailability or replacement of LIBOR may affect
the value, liquidity or return on certain fund investments and may result in


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ADDITIONAL INFORMATION (CONTINUED)
--------------------------------------------------------------------------------

               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

costs incurred in connection with closing out positions and entering into new
trades. Any potential effects of the transition away from LIBOR on the fund or
on certain instruments in which the fund invests can be difficult to ascertain,
and they may vary depending on a variety of factors, and they could result in
losses to the fund.

MANAGEMENT RISK. To the extent that a fund is actively managed, it is subject to
management risk. In managing an actively-managed fund's investment portfolio,
the fund's portfolio managers will apply investment techniques and risk analyses
that may not have the desired result. There can be no guarantee that a fund will
meet its investment objective.

MARKET RISK. Securities held by a fund, as well as shares of a fund itself, are
subject to market fluctuations caused by factors such as general economic
conditions, political events, regulatory or market developments, changes in
interest rates and perceived trends in securities prices. Shares of a fund could
decline in value or underperform other investments as a result of the risk of
loss associated with these market fluctuations. In addition, local, regional or
global events such as war, acts of terrorism, spread of infectious diseases or
other public health issues, recessions, or other events could have a significant
negative impact on a fund and its investments. Such events may affect certain
geographic regions, countries, sectors and industries more significantly than
others. In February 2022, Russia invaded Ukraine which has caused and could
continue to cause significant market disruptions and volatility within the
markets in Russia, Europe, and the United States. The hostilities and sanctions
resulting from those hostilities could have a significant impact on certain fund
investments as well as fund performance. The outbreak of the respiratory disease
designated as COVID-19 in December 2019 has caused significant volatility and
declines in global financial markets, which have caused losses for investors.
While the development of vaccines has slowed the spread of the virus and allowed
for the resumption of "reasonably" normal business activity in the United
States, many countries continue to impose lockdown measures in an attempt to
slow the spread. Additionally, there is no guarantee that vaccines will be
effective against emerging variants of the disease.

NON-U.S. SECURITIES RISK. To the extent a fund invests in non-U.S. securities,
it is subject to additional risks not associated with securities of domestic
issuers. Non-U.S. securities are subject to higher volatility than securities of
domestic issuers due to: possible adverse political, social or economic
developments; restrictions on foreign investment or exchange of securities;
capital controls; lack of liquidity; currency exchange rates; excessive
taxation; government seizure of assets; the imposition of sanctions by foreign
governments; different legal or accounting standards; and less government
supervision and regulation of exchanges in foreign countries. Investments in
non-U.S. securities may involve higher costs than investments in U.S.
securities, including higher transaction and custody costs, as well as
additional taxes imposed by non-U.S. governments. These risks may be heightened
for securities of companies located, or with significant operations, in emerging
market countries.

OPERATIONAL RISK. Each fund is subject to risks arising from various operational
factors, including, but not limited to, human error, processing and
communication errors, errors of a fund's service providers, counterparties or
other third-parties, failed or inadequate processes and technology or systems
failures. Each fund relies on third-parties for a range of services, including
custody. Any delay or failure relating to engaging or maintaining such service
providers may affect a fund's ability to meet its investment objective. Although
the funds and the funds' investment advisor seek to reduce these operational
risks through controls and procedures, there is no way to completely protect
against such risks.

PASSIVE INVESTMENT RISK. To the extent a fund seeks to track an index, the fund
will invest in the securities included in, or representative of, the index
regardless of their investment merit. A fund generally will not attempt to take
defensive positions in declining markets.

VALUATION RISK. The valuation of municipal bonds or securitized assets may carry
more risk than that of common stock. Uncertainties in the conditions of the
financial markets, unreliable reference data, lack of transparency and
inconsistency of valuation models and processes may lead to inaccurate asset
pricing. The Fund may hold investments in sizes smaller than
institutionally-sized round lot positions (sometimes referred to as odd lots).
However, third-party pricing services generally provide evaluations on the basis
of institutionally-sized round lots. If the Fund sells certain of its
investments in an odd lot transaction, the sale price may be less than the value
at which such securities have been held by the Fund. Odd lots often trade at
lower prices than institutional round lots. There is no assurance that the Fund
will be able to sell a portfolio security at the price established by the
pricing service, which could result in a loss to the Fund.

            NOT FDIC INSURED   NOT BANK GUARANTEED   MAY LOSE VALUE

                       LIQUIDITY RISK MANAGEMENT PROGRAM

In accordance with Rule 22e-4 under the Investment Company Act of 1940, as
amended (the "1940 Act"), the Fund and each other fund in the First Trust Fund
Complex, other than the closed-end funds, have adopted and implemented a
liquidity risk management program (the "Program") reasonably designed to assess
and manage the funds' liquidity risk, i.e., the risk that a fund could not meet
requests to redeem shares issued by the fund without significant dilution of
remaining investors' interests in the fund. The Board of Trustees of the First


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ADDITIONAL INFORMATION (CONTINUED)
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               FIRST TRUST LOW DURATION OPPORTUNITIES ETF (LMBS)
                           APRIL 30, 2022 (UNAUDITED)

Trust Funds has appointed First Trust Advisors L.P. (the "Advisor") as the
person designated to administer the Program, and in this capacity the Advisor
performs its duties primarily through the activities and efforts of the First
Trust Liquidity Committee (the "Liquidity Committee").

Pursuant to the Program, the Liquidity Committee classifies the liquidity of
each fund's portfolio investments into one of the four liquidity categories
specified by Rule 22e-4: highly liquid investments, moderately liquid
investments, less liquid investments and illiquid investments. The Liquidity
Committee determines certain of the inputs for this classification process,
including reasonably anticipated trade sizes and significant investor dilution
thresholds. The Liquidity Committee also determines and periodically reviews a
highly liquid investment minimum for certain funds, monitors the funds' holdings
of assets classified as illiquid investments to seek to ensure they do not
exceed 15% of a fund's net assets and establishes policies and procedures
regarding redemptions in kind.

At the April 18, 2022 meeting of the Board of Trustees, as required by Rule
22e-4 and the Program, the Advisor provided the Board with a written report
prepared by the Advisor that addressed the operation of the Program during the
period from March 16, 2021 through the Liquidity Committee's annual meeting held
on March 17, 2022 and assessed the Program's adequacy and effectiveness of
implementation during this period, including the operation of the highly liquid
investment minimum for each fund that is required under the Program to have one,
and any material changes to the Program. Note that because the Fund primarily
holds assets that are highly liquid investments, the Fund has not adopted any
highly liquid investment minimum.

As stated in the written report, during the review period, no fund breached the
15% limitation on illiquid investments, no fund with a highly liquid investment
minimum breached that minimum and no fund filed a Form N-LIQUID. The Advisor
concluded that each fund's investment strategy is appropriate for an open-end
fund; that the Program operated effectively in all material respects during the
review period; and that the Program is reasonably designed to assess and manage
the liquidity risk of each fund and to maintain compliance with Rule 22e-4.


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FIRST TRUST

First Trust Exchange-Traded Fund IV

INVESTMENT ADVISOR
First Trust Advisors L.P.
120 East Liberty Drive, Suite 400
Wheaton, IL 60187

ADMINISTRATOR, CUSTODIAN,
FUND ACCOUNTANT &
TRANSFER AGENT
The Bank of New York Mellon
240 Greenwich Street
New York, NY 10286

INDEPENDENT REGISTERED
PUBLIC ACCOUNTING FIRM
Deloitte & Touche LLP
111 S. Wacker Drive
Chicago, IL 60606

LEGAL COUNSEL
Chapman and Cutler LLP
320 South Canal Street
Chicago, IL 60606





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