First Trust Exchange-Traded Fund VI

First Trust Nasdaq Bank ETF (FTXO)

First Trust Nasdaq Food & Beverage ETF (FTXG)

First Trust Nasdaq Oil & Gas ETF (FTXN)

First Trust Nasdaq Pharmaceuticals ETF (FTXH)

First Trust S-Network E-Commerce ETF (ISHP)
(formerly known as First Trust Nasdaq Retail ETF)

First Trust Nasdaq Semiconductor ETF (FTXL)

First Trust Nasdaq Transportation ETF (FTXR)

First Trust S-Network Streaming & Gaming ETF (BNGE)

Semi-Annual Report
For the Period Ended
September 30, 2022

 


Table of Contents
First Trust Exchange-Traded Fund VI
Semi-Annual Report
September 30, 2022

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Fund Performance Overview

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Portfolio of Investments

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Table of Contents
Caution Regarding Forward-Looking Statements
This report contains certain forward-looking statements within the meaning of the Securities Act of 1933, as amended, and the Securities Exchange Act of 1934, as amended. Forward-looking statements include statements regarding the goals, beliefs, plans or current expectations of First Trust Advisors L.P. (“First Trust” or the “Advisor”) and its representatives, taking into account the information currently available to them. Forward-looking statements include all statements that do not relate solely to current or historical fact. For example, forward-looking statements include the use of words such as “anticipate,” “estimate,” “intend,” “expect,” “believe,” “plan,” “may,” “should,” “would” or other words that convey uncertainty of future events or outcomes.
Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the actual results, performance or achievements of any series of First Trust Exchange-Traded Fund VI (the “Trust”) described in this report (each such series is referred to as a “Fund” and collectively, the “Funds”) to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. When evaluating the information included in this report, you are cautioned not to place undue reliance on these forward-looking statements, which reflect the judgment of the Advisor and its representatives only as of the date hereof. We undertake no obligation to publicly revise or update these forward-looking statements to reflect events and circumstances that arise after the date hereof.
Performance and Risk Disclosure
There is no assurance that any Fund described in this report will achieve its investment objective. Each Fund is subject to market risk, which is the possibility that the market values of securities owned by the Fund will decline and that the value of the Fund’s shares may therefore be less than what you paid for them. Accordingly, you can lose money by investing in a Fund. See “Risk Considerations” in the Additional Information section of this report for a discussion of certain other risks of investing in the Funds.
Performance data quoted represents past performance, which is no guarantee of future results, and current performance may be lower or higher than the figures shown. For the most recent month-end performance figures, please visit www.ftportfolios.com or speak with your financial advisor. Investment returns, net asset value and share price will fluctuate and Fund shares, when sold, may be worth more or less than their original cost.
The Advisor may also periodically provide additional information on Fund performance on each Fund’s web page at www.ftportfolios.com.
How to Read This Report
This report contains information that may help you evaluate your investment. It includes details about each Fund and presents data and analysis that provide insight into each Fund’s performance and investment approach.
By reading the market overview by Robert F. Carey, Chief Market Strategist of the Advisor, you may obtain an understanding of how the market environment affected the performance of each Fund. The statistical information that follows may help you understand each Fund’s performance compared to that of relevant market benchmarks.
It is important to keep in mind that the opinions expressed by personnel of the Advisor are just that: informed opinions. They should not be considered to be promises or advice. The opinions, like the statistics, cover the period through the date on the cover of this report. The material risks of investing in each Fund are spelled out in the prospectus, the statement of additional information, and other Fund regulatory filings.
Page 1

Table of Contents
Shareholder Letter
First Trust Exchange-Traded Fund VI
Semi-Annual Letter from the Chairman and CEO
September 30, 2022
Dear Shareholders,
First Trust is pleased to provide you with the semi-annual report for certain series of the First Trust Exchange-Traded Fund VI (the “Funds”), which contains detailed information about the Funds for the six months ended September 30, 2022.
It is times like these that really test the mettle of investors. Are you someone that is implementing an investment plan with a long time horizon, a trader by nature, or do you fall somewhere in between? Frankly, the current climate is challenging for just about any strategy. While most investors are accustomed to dealing with high levels of volatility in the stock market, some of the daily swings we have witnessed lately have not only been uncharacteristically sharp but have occasionally seemed nearly inexplicable, in my opinion.
In case you have not noticed, volatility is also elevated in the fixed-income market. Bond valuations are down big in 2022. Year-to-date through October 31, 2022, the ICE BofA 15+ Year U.S. Treasury Index experienced a price decline of 33.51%, according to Bloomberg. It was down 31.87% on a total return basis, which includes reinvested interest. To put this into perspective, over the past 40 years, the worst annual showing by the U.S. Long-Term Government Bond Index (20-Year) tracked by Morningstar was the -14.90% total return posted in 2009 (think 2008-2009 global financial crisis). For those who may be unaware, investors benefitted from a trend of declining bond yields from September 1981 through August 2020. While that is an incredible run, nothing lasts forever. Suffice it to say, a lot of pain has been endured by investors in the markets this year and we believe there could be more to come in the near-term. The aggressive interest rate hikes by the Federal Reserve (the “Fed”) are a signal to the markets that it is behind the inflation curve. Moving forward, the Fed will be looking to lower inflation while simultaneously engineering a soft landing in the economy. That will be easier said than done, in my opinion.
There are far more headwinds challenging the securities markets than tailwinds. Here are just a few of those headwinds: stubbornly high inflation; additional rate hikes expected from the Fed from their November and December 2022 meetings, which could potentially push bond yields higher; the ongoing war between Russia and Ukraine, which is impacting the supply and prices of crude oil and natural gas; China enforcing a zero-tolerance policy to combat the spread of the coronavirus by locking down entire cities to its own economic detriment; and the potential for food and energy shortages this coming winter. With the housing market looking like it is finally cooling off, due largely to a huge spike in mortgage rates this year, which were up more than double the rate at the start of the year, the last big tailwind standing may just be the strong U.S. labor market. If the job market can hang in there, the Fed’s goal of a soft landing for the economy may be attainable. I think we will have a clearer picture of things at the start of 2023.
Year-to-date through October 31, 2022, the S&P 500® Index (the “Index”) posted a total return of -17.70%, according to Bloomberg, which puts the Index in bear market territory. A bear market is defined as a 20% or greater decline in the price of a security or index from its most recent peak. While the 17.70% decline in the Index would technically qualify as a stock market correction, investors should continue to view the current downturn as a bear market, in my opinion. Keep in mind, since World War II, there have been 12 bear markets in the Index, excluding the current bear market, according to Yardeni Research. The average price decline of those 12 bear markets was 33.6%. The average price gain over the 12-months following the trough reached during those bear markets was 40.8%, according to Bloomberg. Bear markets come and go. You can’t catch the turn if you are not in the market when the turn comes.
Thank you for giving First Trust the opportunity to play a role in your financial future. We value our relationship with you and will report on the Funds again in six months.
Sincerely,
James A. Bowen
Chairman of the Board of Trustees
Chief Executive Officer of First Trust Advisors L.P.
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Table of Contents
Market Overview
First Trust Exchange-Traded Fund VI
Semi-Annual Report
September 30, 2022
Robert F. Carey, CFA
Senior Vice President and Chief Market Strategist
First Trust Advisors L.P.
Mr. Carey is responsible for the overall management of research and analysis of the First Trust product line. Mr. Carey has more than 30 years of experience as an Equity and Fixed-Income Analyst and is a recipient of the Chartered Financial Analyst (“CFA”) designation. He is a graduate of the University of Illinois at Champaign-Urbana with a B.S. in Physics. He is also a member of the Investment Analysts Society of Chicago and the CFA Institute. Mr. Carey has appeared as a guest on such programs as Bloomberg TV, CNBC, and WBBM Radio, and has been quoted by several publications, including The Wall Street Journal, The Wall Street Reporter, Bloomberg News Service, and Registered Rep.
State of the Global Economy
The International Monetary Fund (“IMF”) reported in its October release that global gross domestic product (“GDP”) growth is expected to come in at 3.2% in 2022 and 2.7% in 2023, down from 6.0% in 2021. The IMF sees the U.S. economy growing 1.6% in 2022 and 1.0% in 2023, down from 5.7% in 2021. With respect to all Advanced Economies, the IMF is projecting GDP growth of 2.4% in 2022 and 1.1% in 2023, down from 5.2% in 2021. Lastly, it sees Emerging Markets and Developing Economies growing 3.7% in 2022 and 3.7% again in 2023, down from 6.6% in 2021. From 1970 to 2021, the average global GDP growth rate was 3.6%, according to the IMF. Looking ahead, the IMF notes that the global economy must navigate three key pressures: the war in Ukraine, world-wide inflation and continued economic headwinds in the U.S., Europe and China.
Russia’s war with Ukraine continues to destabilize the global economy, increasing the cost of living and impeding economic growth. European natural gas prices have spiked four-fold since 2021, according to the IMF. Russia has decreased natural gas deliveries to Europe by over 80% of their 2021 total, greatly increasing the likelihood of an energy shortage. Worldwide inflationary pressures continue to fester, with global inflation forecast to surge to 8.8% in 2022, up from 4.7% in 2021. Central banks have rapidly tightened monetary policy in response, and will likely have to continue to do so, in our opinion. These tighter financial conditions have produced significant headwinds to growth among most major economies and are likely to have at least some impact in 2023.
Performance of Global Stocks and Bonds
U.S. equities have turned negative over the past six-month period. The S&P 500® (the “Index”), S&P MidCap 400® and S&P SmallCap 600® Indices posted total returns of -20.20%, -17.50% and -18.58%, respectively, for the six-month period ended September 30, 2022, according to Bloomberg. Value stocks outperformed growth stocks over the period. The S&P 500® Value Index posted a total return of -16.43% versus -23.87% for the S&P 500® Growth Index; an indication that investors may be anticipating slower growth over the near-term and are opting for companies that are trading at more attractive valuations. All eleven sectors that comprise the Index were down on a total return basis. Energy was down least for the period, losing 2.94%, while the worst showing came from Communication Services, down 30.79%.
A Bloomberg survey of 23 equity strategists found that the average 2022 year-end price target for the Index was 4,346 as of September 15, 2022, down from 4,376 on August 16, 2022, according to its own release. Heading into 2022 (December 16, 2021), strategists had an average target of 4,950. The highest and lowest estimates on September 15, 2022, were 5,100 and 3,400, respectively. On September 15, 2022, the Index closed at 3,901.35, which was 18.66% below its all-time closing high of 4,796.56 on January 3, 2022. As of September 30, 2022, Bloomberg’s 2022, 2023 and 2024 consensus earnings growth rate estimates for the Index stood at 9.61%, 6.14% and 8.44%, respectively.
The performance of foreign equities continues to lag that of major U.S. stock indices. Over the past six months, the MSCI World ex USA and MSCI Emerging Markets equity indices posted total returns of -22.50% (USD) and -21.70% (USD), respectively, according to Bloomberg. Major foreign bond indices were also in negative territory. The Bloomberg Global Aggregate Index of higher quality debt posted a total return of -14.63% (USD), while the EM Hard Currency Aggregate Index of emerging markets debt fell by 13.90% (USD), according to Bloomberg. Over that same period, the U.S. dollar surged by 14.04% against a basket of major currencies, as measured by the U.S. Dollar Index (DXY), pressuring the returns on unhedged foreign securities held by U.S. investors.
U.S. bond indices have not been immune to the aggressive tightening of monetary policy by central banks, particularly the U.S. Federal Reserve. Over the past six months, the best performing index we track was the U.S. Treasury: Intermediate Index, which posted a total return of -4.69%. The worst performer was the Municipal Long Bond: Long Bond (22+), which posted a total return of -12.15%. The yield on the benchmark 10-Year Treasury Note (“T-Note”) rose by 149 basis points (a 63.70% increase over the period) to close at 3.83%, according to Bloomberg. For comparative purposes, the average yield on the 10-Year T-Note was 2.10% for the 10-year period ended September 30, 2022.
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Table of Contents
Fund Performance Overview (Unaudited)
First Trust Nasdaq Bank ETF (FTXO)
The First Trust Nasdaq Bank ETF (the “Fund”) seeks investment results that correspond generally to the price and yield (before the Fund’s fees and expenses) of an equity index called the Nasdaq US Smart Banks IndexTM (the “Index”). The shares of the Fund are listed and trade on The Nasdaq Stock Market LLC under the ticker symbol “FTXO.” The Fund will normally invest at least 90% of its net assets (including investment borrowings) in the common stocks and depositary receipts that comprise the Index. The Index is owned and is developed, maintained and sponsored by Nasdaq, Inc. (the “Index Provider”).
The Index is designed to provide exposure to U.S. companies comprising the banking sector that have been selected based upon their liquidity and weighted based upon their cumulative score on three investing factors: volatility, value and growth. The Index’s initial selection universe consists of the component securities of the Nasdaq US Benchmark Index that have been classified as comprising the banking sector according to the Industry Classification Benchmark. The Nasdaq US Benchmark Index is an index seeking to track the performance of small, mid and large capitalization U.S. companies. This classification includes companies providing a broad range of financial services, including retail banking, loans and money transmissions.
Performance
      Average Annual Total Returns   Cumulative Total Returns
  6 Months
Ended
9/30/22
1 Year
Ended
9/30/22
5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
  5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
Fund Performance              
NAV -17.16% -18.52% 1.40% 6.89%   7.22% 49.44%
Market Price -17.18% -18.54% 1.41% 6.90%   7.26% 49.50%
Index Performance              
Nasdaq US Smart Banks IndexTM -16.98% -18.10% 2.06% 7.60%   10.76% 55.50%
Nasdaq US Benchmark Banks Index -19.12% -23.82% 2.31% 8.02%   12.11% 59.17%
Nasdaq US Benchmark Index -20.68% -18.01% 8.68% 10.51%   51.60% 82.63%
(See Notes to Fund Performance Overview on page 20.)

Nasdaq® and Nasdaq US Smart Banks IndexTM are registered trademarks and service marks of Nasdaq, Inc. (together with its affiliates hereinafter referred to as the “Corporations”) and are licensed for use by First Trust. The Fund has not been passed on by the Corporations as to its legality or suitability. The Fund is not issued, endorsed, sold or promoted by the Corporations. THE CORPORATIONS MAKE NO WARRANTIES AND BEAR NO LIABILITY WITH RESPECT TO THE FUND.
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Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Bank ETF (FTXO) (Continued)
Sector Allocation % of Total
Investments
Financials 100.0%
Total 100.0%
Top Ten Holdings % of Total
Investments
M&T Bank Corp. 8.1%
Popular, Inc. 8.1
Regions Financial Corp. 8.0
Wells Fargo & Co. 8.0
New York Community Bancorp, Inc. 7.5
Cullen/Frost Bankers, Inc. 4.4
Old National Bancorp 4.3
First Citizens BancShares, Inc., Class A 4.2
PNC Financial Services Group (The), Inc. 4.1
Synovus Financial Corp. 4.0
Total 60.7%
  
Performance figures assume reinvestment of all distributions and do not reflect the deduction of taxes that a shareholder would pay on Fund distributions or the redemption or sale of Fund shares. An index is a statistical composite that tracks a specified financial market or sector. Unlike the Fund, the indices do not actually hold a portfolio of securities and therefore do not incur the expenses incurred by the Fund. These expenses negatively impact the performance of the Fund. The Fund’s past performance does not predict future performance. 
Frequency Distribution of Discounts and Premiums
Information showing the number of days the market price of the Fund’s shares was greater (at a premium) and less (at a discount) than the Fund’s net asset value for the most recently completed year, and the most recently completed calendar quarters since that year (or life of the Fund, if shorter), is available at https://www.ftportfolios.com/Retail/etf/home.aspx.
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Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Food & Beverage ETF (FTXG)
The First Trust Nasdaq Food & Beverage ETF (the “Fund”) seeks investment results that correspond generally to the price and yield (before the Fund’s fees and expenses) of an equity index called the Nasdaq US Smart Food & Beverage IndexTM (the “Index”). The shares of the Fund are listed and trade on The Nasdaq Stock Market LLC under the ticker symbol “FTXG.” The Fund will normally invest at least 90% of its net assets (including investment borrowings) in the common stocks and depositary receipts that comprise the Index. The Index is owned and is developed, maintained and sponsored by Nasdaq, Inc. (the “Index Provider”).
The Index is designed to provide exposure to U.S. companies comprising the food and beverage sector that have been selected based upon their liquidity and weighted based upon their cumulative score on three investing factors: volatility, value and growth. The Index’s initial selection universe consists of the component securities of the Nasdaq US Benchmark Index that have been classified as comprising either the beverages sector or food producers sector according to the Industry Classification Benchmark (“ICB”). The Nasdaq US Benchmark Index is an index seeking to track the performance of small, mid and large capitalization U.S. companies. These classifications include: (i) manufacturers and shippers of cider or malt products; (ii) producers, distillers, vintners, blenders and shippers of wine and spirits; (iii) manufacturers, bottlers and distributors of non-alcoholic beverages; (iv) companies that grow crops or raise livestock, operate fisheries or own non-tobacco plantations; (v) food producers, including meatpacking, snacks, fruits, vegetables, dairy products and frozen seafood; (vi) producers of pet food; and (vii) manufacturers of dietary supplements, vitamins and related items.
Performance
      Average Annual Total Returns   Cumulative Total Returns
  6 Months
Ended
9/30/22
1 Year
Ended
9/30/22
5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
  5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
Fund Performance              
NAV -7.76% 4.27% 6.16% 5.13%   34.82% 35.17%
Market Price -7.82% 4.35% 6.15% 5.14%   34.78% 35.27%
Index Performance              
Nasdaq US Smart Food & Beverage IndexTM -7.51% 4.92% 6.84% 5.80%   39.18% 40.46%
Nasdaq US Benchmark Food, Beverage and Tobacco Index -6.99% 4.35% 7.80% 7.07%   45.60% 50.99%
Nasdaq US Benchmark Index -20.68% -18.01% 8.68% 10.51%   51.60% 82.63%
(See Notes to Fund Performance Overview on page 20.)

Nasdaq® and Nasdaq US Smart Food & Beverage IndexTM are registered trademarks and service marks of Nasdaq, Inc. (together with its affiliates hereinafter referred to as the “Corporations”) and are licensed for use by First Trust. The Fund has not been passed on by the Corporations as to its legality or suitability. The Fund is not issued, endorsed, sold or promoted by the Corporations. THE CORPORATIONS MAKE NO WARRANTIES AND BEAR NO LIABILITY WITH RESPECT TO THE FUND.
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Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Food & Beverage ETF (FTXG) (Continued)
Sector Allocation % of Total
Investments
Consumer Staples 96.0%
Materials 4.0
Total 100.0%
Top Ten Holdings % of Total
Investments
Kellogg Co. 8.3%
General Mills, Inc. 8.1
Molson Coors Beverage Co., Class B 7.8
Campbell Soup Co. 7.6
Bunge Ltd. 7.2
Hostess Brands, Inc. 4.3
J.M. Smucker (The) Co. 4.2
Hershey (The) Co. 4.2
Conagra Brands, Inc. 4.1
PepsiCo, Inc. 4.1
Total 59.9%
  
Performance figures assume reinvestment of all distributions and do not reflect the deduction of taxes that a shareholder would pay on Fund distributions or the redemption or sale of Fund shares. An index is a statistical composite that tracks a specified financial market or sector. Unlike the Fund, the indices do not actually hold a portfolio of securities and therefore do not incur the expenses incurred by the Fund. These expenses negatively impact the performance of the Fund. The Fund’s past performance does not predict future performance. 
Frequency Distribution of Discounts and Premiums
Information showing the number of days the market price of the Fund’s shares was greater (at a premium) and less (at a discount) than the Fund’s net asset value for the most recently completed year, and the most recently completed calendar quarters since that year (or life of the Fund, if shorter), is available at https://www.ftportfolios.com/Retail/etf/home.aspx.
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Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Oil & Gas ETF (FTXN)
The First Trust Nasdaq Oil & Gas ETF (the “Fund”) seeks investment results that correspond generally to the price and yield (before the Fund’s fees and expenses) of an equity index called the Nasdaq US Smart Oil & Gas IndexTM (the “Index”). The shares of the Fund are listed and trade on The Nasdaq Stock Market LLC under the ticker symbol “FTXN.” The Fund will normally invest at least 90% of its net assets (including investment borrowings) in the common stocks and depositary receipts that comprise the Index. The Index is owned and is developed, maintained and sponsored by Nasdaq, Inc. (the “Index Provider”).
The Index is designed to provide exposure to U.S. companies comprising the oil and gas sector that have been selected based upon their liquidity and weighted based upon their cumulative score on three investing factors: volatility, value and growth. The Index’s initial selection universe consists of the component securities of the Nasdaq US Benchmark Index that have been classified as comprising either the oil & gas producers sector or the oil equipment, services & distribution sector according to the Industry Classification Benchmark (“ICB”). The Nasdaq US Benchmark Index is an index seeking to track the performance of small, mid and large capitalization U.S. companies. These classifications include: (i) companies engaged in the exploration for and drilling, production, refining and supply of oil and gas products; (ii) integrated oil and gas companies engaged in the exploration for, and drilling, production, refining, distribution and retail sales of, oil and gas products; (iii) suppliers of equipment and services to oil fields and offshore platforms, such as drilling, exploration, seismic-information services and platform construction; and (iv) operators of pipelines carrying oil, gas or other forms of fuel.
Performance
      Average Annual Total Returns   Cumulative Total Returns
  6 Months
Ended
9/30/22
1 Year
Ended
9/30/22
5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
  5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
Fund Performance              
NAV -6.13% 31.67% 7.40% 5.56%   42.89% 38.54%
Market Price -6.13% 31.60% 7.40% 5.56%   42.89% 38.55%
Index Performance              
Nasdaq US Smart Oil & Gas IndexTM -6.01% 32.32% 8.09% 6.22%   47.52% 43.90%
Nasdaq US Benchmark Energy Index -2.28% 42.75% 6.19% 6.02%   35.06% 42.23%
Nasdaq US Benchmark Index -20.68% -18.01% 8.68% 10.51%   51.60% 82.63%
(See Notes to Fund Performance Overview on page 20.)

Nasdaq® and Nasdaq US Smart Oil & Gas IndexTM are registered trademarks and service marks of Nasdaq, Inc. (together with its affiliates hereinafter referred to as the “Corporations”) and are licensed for use by First Trust. The Fund has not been passed on by the Corporations as to its legality or suitability. The Fund is not issued, endorsed, sold or promoted by the Corporations. THE CORPORATIONS MAKE NO WARRANTIES AND BEAR NO LIABILITY WITH RESPECT TO THE FUND.
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Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Oil & Gas ETF (FTXN) (Continued)
Sector Allocation % of Total
Investments
Energy 100.0%
Total 100.0%
Top Ten Holdings % of Total
Investments
PBF Energy, Inc., Class A 9.3%
Occidental Petroleum Corp. 7.8
Chevron Corp. 6.8
Exxon Mobil Corp. 6.8
Williams (The) Cos., Inc. 6.2
Marathon Petroleum Corp. 4.4
ConocoPhillips 4.2
Kinder Morgan, Inc. 4.1
Marathon Oil Corp. 4.0
Valero Energy Corp. 4.0
Total 57.6%
  
Performance figures assume reinvestment of all distributions and do not reflect the deduction of taxes that a shareholder would pay on Fund distributions or the redemption or sale of Fund shares. An index is a statistical composite that tracks a specified financial market or sector. Unlike the Fund, the indices do not actually hold a portfolio of securities and therefore do not incur the expenses incurred by the Fund. These expenses negatively impact the performance of the Fund. The Fund’s past performance does not predict future performance. 
Frequency Distribution of Discounts and Premiums
Information showing the number of days the market price of the Fund’s shares was greater (at a premium) and less (at a discount) than the Fund’s net asset value for the most recently completed year, and the most recently completed calendar quarters since that year (or life of the Fund, if shorter), is available at https://www.ftportfolios.com/Retail/etf/home.aspx.
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Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Pharmaceuticals ETF (FTXH)
The First Trust Nasdaq Pharmaceuticals ETF (the “Fund”) seeks investment results that correspond generally to the price and yield (before the Fund’s fees and expenses) of an equity index called the Nasdaq US Smart Pharmaceuticals IndexTM (the “Index”). The shares of the Fund are listed and trade on The Nasdaq Stock Market LLC under the ticker symbol “FTXH.” The Fund will normally invest at least 90% of its net assets (including investment borrowings) in the common stocks and depositary receipts that comprise the Index. The Index is owned and is developed, maintained and sponsored by Nasdaq, Inc. (the “Index Provider”).
The Index is designed to provide exposure to U.S. companies comprising the pharmaceutical sector that have been selected based upon their liquidity and weighted based upon their cumulative score on three investing factors: volatility, value and growth. The Index’s initial selection universe consists of the component securities of the Nasdaq US Benchmark Index that have been classified as comprising the pharmaceuticals sub-sector according to the Industry Classification Benchmark. The Nasdaq US Benchmark Index is an index seeking to track the performance of small, mid and large capitalization U.S. companies. This classification includes vaccine producers and manufacturers of prescription or over-the-counter drugs.
Performance
      Average Annual Total Returns   Cumulative Total Returns
  6 Months
Ended
9/30/22
1 Year
Ended
9/30/22
5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
  5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
Fund Performance              
NAV -9.33% -4.71% 4.63% 4.14%   25.40% 27.73%
Market Price -9.08% -4.71% 4.65% 4.16%   25.50% 27.84%
Index Performance              
Nasdaq US Smart Pharmaceuticals IndexTM -9.00% -4.03% 5.31% 4.83%   29.53% 32.91%
Nasdaq US Benchmark Pharmaceuticals Index -5.48% 10.20% 10.94% 11.18%   68.05% 89.45%
Nasdaq US Benchmark Index -20.68% -18.01% 8.68% 10.51%   51.60% 82.63%
(See Notes to Fund Performance Overview on page 20.)

Nasdaq® and Nasdaq US Smart Pharmaceuticals IndexTM are registered trademarks and service marks of Nasdaq, Inc. (together with its affiliates hereinafter referred to as the “Corporations”) and are licensed for use by First Trust. The Fund has not been passed on by the Corporations as to its legality or suitability. The Fund is not issued, endorsed, sold or promoted by the Corporations. THE CORPORATIONS MAKE NO WARRANTIES AND BEAR NO LIABILITY WITH RESPECT TO THE FUND.
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Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Pharmaceuticals ETF (FTXH) (Continued)
Sector Allocation % of Total
Investments
Health Care 100.0%
Total 100.0%
Top Ten Holdings % of Total
Investments
Bristol-Myers Squibb Co. 8.7%
Johnson & Johnson 8.4
Gilead Sciences, Inc. 8.0
Ironwood Pharmaceuticals, Inc. 8.0
Amgen, Inc. 7.8
Eli Lilly & Co. 4.4
Vertex Pharmaceuticals, Inc. 4.3
Merck & Co., Inc. 4.2
AbbVie, Inc. 4.1
Prestige Consumer Healthcare, Inc. 4.1
Total 62.0%
  
Performance figures assume reinvestment of all distributions and do not reflect the deduction of taxes that a shareholder would pay on Fund distributions or the redemption or sale of Fund shares. An index is a statistical composite that tracks a specified financial market or sector. Unlike the Fund, the indices do not actually hold a portfolio of securities and therefore do not incur the expenses incurred by the Fund. These expenses negatively impact the performance of the Fund. The Fund’s past performance does not predict future performance. 
Frequency Distribution of Discounts and Premiums
Information showing the number of days the market price of the Fund’s shares was greater (at a premium) and less (at a discount) than the Fund’s net asset value for the most recently completed year, and the most recently completed calendar quarters since that year (or life of the Fund, if shorter), is available at https://www.ftportfolios.com/Retail/etf/home.aspx.
Page 11

Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust S-Network E-Commerce ETF (ISHP)
The First Trust S-Network E-Commerce ETF (the “Fund”), formerly the First Trust Nasdaq Retail ETF, seeks investment results that correspond generally to the price and yield (before the Fund’s fees and expenses) of an equity index called the S-Network Global E-Commerce IndexTM (the “Index”). The Fund lists and principally trades its shares on The Nasdaq Stock Market LLC under the symbol “ISHP.” The Fund will normally invest at least 90% of its net assets (plus any borrowings for investment purposes) in the common stocks and depository receipts that comprise the Index.
The Index seeks to provide exposure to companies with securities listed on recognized global securities exchanges that are principally engaged in the global e-commerce industry. According to VettaFi LLC, to be eligible for inclusion in the Index, a security must be issued by a company engaged in at least one of the four following business segments comprising the global e-commerce industry: (1) content navigation; (2) online retail; (3) online marketplace; and (4) e-commerce infrastructure. The Index is owned and is developed, maintained and sponsored by VettaFi LLC.
Performance
      Average Annual Total Returns   Cumulative Total Returns
  6 Months
Ended
9/30/22
1 Year
Ended
9/30/22
5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
  5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
Fund Performance              
NAV -30.21% -36.36% 2.65% 2.36%   13.94% 15.07%
Market Price -30.48% -36.70% 2.55% 2.27%   13.42% 14.48%
Index Performance              
S-Network Global E-Commerce IndexTM(1)(2) -30.51% -48.55% N/A N/A   N/A N/A
MSCI ACWI Index(3) -21.41% -20.66% 4.44% 6.89%   24.27% 49.40%
Nasdaq US Smart Retail Index -18.65% -18.63% 8.39% 7.19%   49.61% 52.00%
Nasdaq US Benchmark Retail Index -21.41% -21.95% 12.90% 12.58%   83.46% 104.28%
Nasdaq US Benchmark Index -20.68% -18.01% 8.68% 10.51%   51.60% 82.63%
(See Notes to Fund Performance Overview on page 20.)

(1) On January 26, 2022, the Fund’s underlying index changed from the Nasdaq US Smart Retail Index to the S-Network Global E-Commerce IndexTM. Therefore, performance and historical returns shown for the periods prior to January 26, 2022, are not necessarily indicative of the performance of the Fund, based on its current Index, would have generated.
(2) Because the Fund’s new underlying Index had an inception date of April 30, 2021, performance data is not available for all the periods shown in the table for the Index because performance data does not exist for some of the entire periods.
(3) The MSCI ACWI Index serves as the Fund’s new primary benchmark index. The Fund’s investment advisor determined that the MSCI ACWI Index provides a more appropriate comparison to Fund returns.
S-Network and S-Network Global E-Commerce IndexTM are service marks of VettaFi LLC and have been licensed for use by First Trust Advisors L.P. The Fund is not issued, sponsored, endorsed, sold or promoted by VettaFi LLC or its affiliates (collectively, “VettaFi”). VettaFi makes no representation or warranty, express or implied, to the purchasers or owners of the Fund or any member of the public regarding the advisability of investing in securities generally or in the Fund particularly or the ability of the Index to track general market performance.
Page 12

Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust S-Network E-Commerce ETF (ISHP) (Continued)
Sector Allocation % of Total
Investments
Consumer Discretionary 37.2%
Communication Services 22.0
Industrials 17.7
Information Technology 13.9
Real Estate 5.2
Consumer Staples 2.0
Financials 2.0
Total 100.0%
Top Ten Holdings % of Total
Investments
Uber Technologies, Inc. 2.3%
Pinterest, Inc., Class A 2.2
MercadoLibre, Inc. 2.2
PayPal Holdings, Inc. 2.2
Twitter, Inc. 2.2
CoStar Group, Inc. 2.2
Airbnb, Inc., Class A 2.1
KE Holdings, Inc., ADR 2.0
Walmart, Inc. 2.0
Coupang, Inc. 2.0
Total 21.4%
  
Performance figures assume reinvestment of all distributions and do not reflect the deduction of taxes that a shareholder would pay on Fund distributions or the redemption or sale of Fund shares. An index is a statistical composite that tracks a specified financial market or sector. Unlike the Fund, the indices do not actually hold a portfolio of securities and therefore do not incur the expenses incurred by the Fund. These expenses negatively impact the performance of the Fund. The Fund’s past performance does not predict future performance. 
Frequency Distribution of Discounts and Premiums
Information showing the number of days the market price of the Fund’s shares was greater (at a premium) and less (at a discount) than the Fund’s net asset value for the most recently completed year, and the most recently completed calendar quarters since that year (or life of the Fund, if shorter), is available at https://www.ftportfolios.com/Retail/etf/home.aspx.
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Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Semiconductor ETF (FTXL)
The First Trust Nasdaq Semiconductor ETF (the “Fund”) seeks investment results that correspond generally to the price and yield (before the Fund’s fees and expenses) of an equity index called the Nasdaq US Smart Semiconductor IndexTM (the “Index”). The shares of the Fund are listed and trade on The Nasdaq Stock Market LLC under the ticker symbol “FTXL.” The Fund will normally invest at least 90% of its net assets (including investment borrowings) in the common stocks and depositary receipts that comprise the Index. The Index is owned and is developed, maintained and sponsored by Nasdaq, Inc. (the “Index Provider”).
The Index is designed to provide exposure to U.S. companies comprising the semiconductor sector that have been selected based upon their liquidity and weighted based upon their cumulative score on three investing factors: volatility, value and growth. The Index’s initial selection universe consists of the component securities of the Nasdaq US Benchmark Index that have been classified as comprising the semiconductors sub-sector according to the Industry Classification Benchmark. The Nasdaq US Benchmark Index is an index seeking to track the performance of small, mid and large capitalization U.S. companies. This classification includes producers and distributors of semiconductors and other integrated chips, including other products related to the semiconductor industry, such as semiconductor capital equipment and motherboards.
Performance
      Average Annual Total Returns   Cumulative Total Returns
  6 Months
Ended
9/30/22
1 Year
Ended
9/30/22
5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
  5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
Fund Performance              
NAV -30.21% -27.30% 12.15% 16.68%   77.40% 153.37%
Market Price -30.30% -27.41% 12.14% 16.68%   77.34% 153.37%
Index Performance              
Nasdaq US Smart Semiconductor IndexTM -30.05% -26.90% 12.84% 17.42%   82.95% 163.23%
Nasdaq US Benchmark Semiconductors IndexTM -38.06% -29.82% 13.09% 16.23%   84.99% 147.53%
Nasdaq US Benchmark Index -20.68% -18.01% 8.68% 10.51%   51.60% 82.63%
(See Notes to Fund Performance Overview on page 20.)

Nasdaq® and Nasdaq US Smart Semiconductor IndexTM are registered trademarks and service marks of Nasdaq, Inc. (together with its affiliates hereinafter referred to as the “Corporations”) and are licensed for use by First Trust. The Fund has not been passed on by the Corporations as to its legality or suitability. The Fund is not issued, endorsed, sold or promoted by the Corporations. THE CORPORATIONS MAKE NO WARRANTIES AND BEAR NO LIABILITY WITH RESPECT TO THE FUND.
Page 14

Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Semiconductor ETF (FTXL) (Continued)
Sector Allocation % of Total
Investments
Information Technology 98.6%
Health Care 1.4
Total 100.0%
Top Ten Holdings % of Total
Investments
Texas Instruments, Inc. 8.6%
ON Semiconductor Corp. 8.3
Broadcom, Inc. 8.2
Skyworks Solutions, Inc. 7.9
Intel Corp. 7.4
Microchip Technology, Inc. 4.3
Analog Devices, Inc. 4.2
NXP Semiconductors N.V. 4.1
Micron Technology, Inc. 4.1
Qorvo, Inc. 4.1
Total 61.2%
  
Performance figures assume reinvestment of all distributions and do not reflect the deduction of taxes that a shareholder would pay on Fund distributions or the redemption or sale of Fund shares. An index is a statistical composite that tracks a specified financial market or sector. Unlike the Fund, the indices do not actually hold a portfolio of securities and therefore do not incur the expenses incurred by the Fund. These expenses negatively impact the performance of the Fund. The Fund’s past performance does not predict future performance. 
Frequency Distribution of Discounts and Premiums
Information showing the number of days the market price of the Fund’s shares was greater (at a premium) and less (at a discount) than the Fund’s net asset value for the most recently completed year, and the most recently completed calendar quarters since that year (or life of the Fund, if shorter), is available at https://www.ftportfolios.com/Retail/etf/home.aspx.
Page 15

Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Transportation ETF (FTXR)
The First Trust Nasdaq Transportation ETF (the “Fund”) seeks investment results that correspond generally to the price and yield (before the Fund’s fees and expenses) of an equity index called the Nasdaq US Smart Transportation IndexTM (the “Index”). The shares of the Fund are listed and trade on The Nasdaq Stock Market LLC under the ticker symbol “FTXR.” The Fund will normally invest at least 90% of its net assets (including investment borrowings) in the common stocks and depositary receipts that comprise the Index. The Index is owned and is developed, maintained and sponsored by Nasdaq, Inc. (the “Index Provider”).
The Index is designed to provide exposure to U.S. companies comprising the transportation sector that have been selected based upon their liquidity and weighted based upon their cumulative score on three investing factors: volatility, value and growth. The Index’s initial selection universe consists of the component securities of the Nasdaq US Benchmark Index that have been classified as comprising the industrial transportation sector, the automobiles & parts sector or the airlines sub-sector according to the Industry Classification Benchmark. The Nasdaq US Benchmark Index is an index seeking to track the performance of small, mid and large capitalization U.S. companies. These classifications include: (i) operators of mail and package delivery services; (ii) providers of on-water transportation for commercial markets; (iii) providers of industrial railway transportation and railway lines; (iv) companies that manage airports, train depots, roads, bridges, tunnels, ports, and providers of logistic services to shippers of goods; (v) companies that provide commercial trucking services; (vi) makers of motorcycles and passenger vehicles; (vii) manufacturers and distributors of new and replacement parts for motorcycles and automobiles; (viii) manufacturers, distributors and retreaders of automobile, truck and motorcycle tires; and (ix) companies providing primarily passenger air transport.
Performance
      Average Annual Total Returns   Cumulative Total Returns
  6 Months
Ended
9/30/22
1 Year
Ended
9/30/22
5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
  5 Years
Ended
9/30/22
Inception
(9/20/16)
to 9/30/22
Fund Performance              
NAV -26.84% -22.74% 0.54% 3.92%   2.72% 26.06%
Market Price -26.86% -22.72% 0.55% 3.92%   2.76% 26.06%
Index Performance              
Nasdaq US Smart Transportation IndexTM -26.81% -22.59% 0.96% 4.40%   4.90% 29.65%
Nasdaq US Benchmark Industrial Transportation IndexTM -24.02% -10.78% 8.89% 12.52%   53.10% 103.57%
Nasdaq US Benchmark Index -20.68% -18.01% 8.68% 10.51%   51.60% 82.63%
(See Notes to Fund Performance Overview on page 20.)

Nasdaq® and Nasdaq US Smart Transportation IndexTM are registered trademarks and service marks of Nasdaq, Inc. (together with its affiliates hereinafter referred to as the “Corporations”) and are licensed for use by First Trust. The Fund has not been passed on by the Corporations as to its legality or suitability. The Fund is not issued, endorsed, sold or promoted by the Corporations. THE CORPORATIONS MAKE NO WARRANTIES AND BEAR NO LIABILITY WITH RESPECT TO THE FUND.
Page 16

Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust Nasdaq Transportation ETF (FTXR) (Continued)
Sector Allocation % of Total
Long-Term
Investments
Industrials 72.9%
Consumer Discretionary 27.1
Total 100.0%
Top Ten Holdings % of Total
Long-Term
Investments
PACCAR, Inc. 9.0%
Union Pacific Corp. 8.2
CH Robinson Worldwide, Inc. 8.0
CSX Corp. 7.9
Ford Motor Co. 6.9
United Rentals, Inc. 4.4
JB Hunt Transport Services, Inc. 4.2
Alaska Air Group, Inc. 4.2
LKQ Corp. 4.2
Lear Corp. 4.1
Total 61.1%
  
Performance figures assume reinvestment of all distributions and do not reflect the deduction of taxes that a shareholder would pay on Fund distributions or the redemption or sale of Fund shares. An index is a statistical composite that tracks a specified financial market or sector. Unlike the Fund, the indices do not actually hold a portfolio of securities and therefore do not incur the expenses incurred by the Fund. These expenses negatively impact the performance of the Fund. The Fund’s past performance does not predict future performance. 
Frequency Distribution of Discounts and Premiums
Information showing the number of days the market price of the Fund’s shares was greater (at a premium) and less (at a discount) than the Fund’s net asset value for the most recently completed year, and the most recently completed calendar quarters since that year (or life of the Fund, if shorter), is available at https://www.ftportfolios.com/Retail/etf/home.aspx.
Page 17

Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust S-Network Streaming & Gaming ETF (BNGE)
The First Trust S-Network Streaming & Gaming ETF (the “Fund”) seeks investment results that correspond generally to the price and yield (before the Fund’s fees and expenses) of an index called the S-Network Streaming & Gaming Index (the “Index”). The Fund lists and principally trades its shares on The NYSE Arca, Inc. under the ticker symbol “BNGE.” The Fund will normally invest at least 80% of its net assets (including investment borrowings) in the common stocks and depositary receipts that comprise the Index. The Fund, using an indexing investment approach, attempts to replicate, before fees and expenses, the performance of the Index.
According to VettaFi LLC (the “Index Provider”), the Index is composed of common stock and depositary receipts issued by U.S. and non-U.S. companies that enable remote users to access online content; publish online content; participate in prospective wagering; spectate or participate in competitive video gaming; and that provide the products, services and technology that are necessary for the streaming and gaming industries. The Index is owned and is developed, maintained and sponsored by VettaFi LLC. The Index Provider retains the right at any time, upon prior written notice, to modify the Index methodology.
Performance
    Cumulative
Total Returns
  6 Months Ended
9/30/22
Inception (1/25/22)
to 9/30/22
Fund Performance    
NAV -31.24% -34.55%
Market Price -31.54% -34.47%
Index Performance    
S-Network Streaming & Gaming Index -31.07% -33.92%
MSCI ACWI Index -21.41% -19.86%
(See Notes to Fund Performance Overview on page 20.)

S-Network and S-Network Streaming & Gaming Index are service marks of VettaFi LLC and have been licensed for use by First Trust Advisors L.P. The Fund is not issued, sponsored, endorsed, sold or promoted by VettaFi LLC or its affiliates (collectively, “VettaFi”). VettaFi makes no representation or warranty, express or implied, to the purchasers or owners of the Fund or any member of the public regarding the advisability of investing in securities generally or in the Fund particularly or the ability of the Index to track general market performance.
Page 18

Table of Contents
Fund Performance Overview (Unaudited) (Continued)
First Trust S-Network Streaming & Gaming ETF (BNGE) (Continued)
Sector Allocation % of Total
Long-Term
Investments
Communication Services 57.0%
Consumer Discretionary 28.9
Information Technology 14.1
Total 100.0%
Top Ten Holdings % of Total
Long-Term
Investments
Netflix, Inc. 6.5%
Walt Disney (The) Co. 5.1
Activision Blizzard, Inc. 5.0
Nintendo Co., Ltd. 4.9
Electronic Arts, Inc. 4.8
Flutter Entertainment PLC 4.6
NetEase, Inc., ADR 4.5
Advanced Micro Devices, Inc. 4.2
Sony Group Corp. 4.1
NVIDIA Corp. 4.0
Total 47.7%
  
Performance figures assume reinvestment of all distributions and do not reflect the deduction of taxes that a shareholder would pay on Fund distributions or the redemption or sale of Fund shares. An index is a statistical composite that tracks a specified financial market or sector. Unlike the Fund, the indices do not actually hold a portfolio of securities and therefore do not incur the expenses incurred by the Fund. These expenses negatively impact the performance of the Fund. The Fund’s past performance does not predict future performance. 
Frequency Distribution of Discounts and Premiums
Information showing the number of days the market price of the Fund’s shares was greater (at a premium) and less (at a discount) than the Fund’s net asset value for the most recently completed year, and the most recently completed calendar quarters since that year (or life of the Fund, if shorter), is available at https://www.ftportfolios.com/Retail/etf/home.aspx.
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Table of Contents
Notes to Fund Performance Overview (Unaudited)
Total returns for the periods since inception are calculated from the inception date of each Fund. “Average Annual Total Returns” represent the average annual change in value of an investment over the periods indicated. “Cumulative Total Returns” represent the total change in value of an investment over the periods indicated.
Each Fund’s per share net asset value (“NAV”) is the value of one share of the Fund and is computed by dividing the value of all assets of the Fund (including accrued interest and dividends), less all liabilities (including accrued expenses and dividends declared but unpaid), by the total number of outstanding shares. The price used to calculate market return (“Market Price”) is determined by using the midpoint of the national best bid and offer price (“NBBO”) as of the time that the Fund’s NAV is calculated. Under SEC rules, the NBBO consists of the highest displayed buy and lowest sell prices among the various exchanges trading the Fund at the time the Fund’s NAV is calculated. Prior to January 1, 2019, the price used was the midpoint between the highest bid and the lowest offer on the stock exchange on which shares of the Fund were listed for trading as of the time that the Fund’s NAV was calculated. Since shares of each Fund did not trade in the secondary market until after the Fund’s inception, for the period from inception to the first day of secondary market trading in shares of the Fund, the NAV of each Fund is used as a proxy for the secondary market trading price to calculate market returns. NAV and market returns assume that all distributions have been reinvested in each Fund at NAV and Market Price, respectively.
An index is a statistical composite that tracks a specified financial market or sector. Unlike each Fund, the indices do not actually hold a portfolio of securities and therefore do not incur the expenses incurred by each Fund. These expenses negatively impact the performance of each Fund. Also, market returns do not include brokerage commissions that may be payable on secondary market transactions. If brokerage commissions were included, market returns would be lower. The total returns presented reflect the reinvestment of dividends on securities in the indices. The returns presented do not reflect the deduction of taxes that a shareholder would pay on Fund distributions or the redemption or sale of Fund shares. The investment return and principal value of shares of each Fund will vary with changes in market conditions. Shares of each Fund may be worth more or less than their original cost when they are redeemed or sold in the market. Each Fund’s past performance is no guarantee of future performance.
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Table of Contents
First Trust Exchange-Traded Fund VI
Understanding Your Fund Expenses
September 30, 2022 (Unaudited)
As a shareholder of First Trust Nasdaq Bank ETF, First Trust Nasdaq Food & Beverage ETF, First Trust Nasdaq Oil & Gas ETF, First Trust Nasdaq Pharmaceuticals ETF, First Trust S-Network E-Commerce ETF, First Trust Nasdaq Semiconductor ETF, First Trust Nasdaq Transportation ETF or First Trust S-Network Streaming & Gaming ETF (each a “Fund” and collectively, the “Funds”), you incur two types of costs: (1) transaction costs; and (2) ongoing costs, including management fees, distribution and/or service (12b-1) fees, if any, and other Fund expenses. This Example is intended to help you understand your ongoing costs of investing in the Funds and to compare these costs with the ongoing costs of investing in other funds.
The Example is based on an investment of $1,000 invested at the beginning of the period and held through the six-month period ended September 30, 2022.
Actual Expenses
The first line in the following table provides information about actual account values and actual expenses. You may use the information in this line, together with the amount you invested, to estimate the expenses that you paid over the period. Simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number in the first line under the heading entitled “Expenses Paid During the Six-Month Period” to estimate the expenses you paid on your account during this six-month period.
Hypothetical Example for Comparison Purposes
The second line in the following table provides information about hypothetical account values and hypothetical expenses based on each Fund’s actual expense ratio and an assumed rate of return of 5% per year before expenses, which is not each Fund’s actual return. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in the Funds and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.
Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs such as brokerage commissions. Therefore, the second line in the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.
  Beginning
Account Value
April 1, 2022
Ending
Account Value
September 30, 2022
Annualized
Expense Ratio
Based on the
Six-Month
Period
Expenses Paid
During the
Six-Month
Period (a)
First Trust Nasdaq Bank ETF (FTXO)
Actual $1,000.00 $828.40 0.60% $2.75
Hypothetical (5% return before expenses) $1,000.00 $1,022.06 0.60% $3.04
First Trust Nasdaq Food & Beverage ETF (FTXG)
Actual $1,000.00 $922.40 0.60% $2.89
Hypothetical (5% return before expenses) $1,000.00 $1,022.06 0.60% $3.04
First Trust Nasdaq Oil & Gas ETF (FTXN)
Actual $1,000.00 $938.70 0.60% $2.92
Hypothetical (5% return before expenses) $1,000.00 $1,022.06 0.60% $3.04
First Trust Nasdaq Pharmaceuticals ETF (FTXH)
Actual $1,000.00 $906.70 0.60% $2.87
Hypothetical (5% return before expenses) $1,000.00 $1,022.06 0.60% $3.04
First Trust S-Network E-Commerce ETF (ISHP)
Actual $1,000.00 $697.90 0.60% $2.55
Hypothetical (5% return before expenses) $1,000.00 $1,022.06 0.60% $3.04
First Trust Nasdaq Semiconductor ETF (FTXL)
Actual $1,000.00 $697.90 0.60% $2.55
Hypothetical (5% return before expenses) $1,000.00 $1,022.06 0.60% $3.04
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Table of Contents
First Trust Exchange-Traded Fund VI
Understanding Your Fund Expenses (Continued)
September 30, 2022 (Unaudited)
  Beginning
Account Value
April 1, 2022
Ending
Account Value
September 30, 2022
Annualized
Expense Ratio
Based on the
Six-Month
Period
Expenses Paid
During the
Six-Month
Period (a)
First Trust Nasdaq Transportation ETF (FTXR)
Actual $1,000.00 $731.60 0.60% $2.60
Hypothetical (5% return before expenses) $1,000.00 $1,022.06 0.60% $3.04
First Trust S-Network Streaming & Gaming ETF (BNGE)
Actual $1,000.00 $687.60 0.70% $2.96
Hypothetical (5% return before expenses) $1,000.00 $1,021.56 0.70% $3.55
    
(a) Expenses are equal to the annualized expense ratios as indicated in the table multiplied by the average account value over the period (April 1, 2022 through September 30, 2022), multiplied by 183/365 (to reflect the six-month period).
Page 22

Table of Contents
First Trust Nasdaq Bank ETF (FTXO)
Portfolio of Investments
September 30, 2022 (Unaudited)
Shares   Description   Value
COMMON STOCKS – 99.7%
    Banks – 88.3%    
259,239   Bank of America Corp.   $7,829,018
178,509   Citigroup, Inc.   7,438,470
93,173   Citizens Financial Group, Inc.   3,201,424
108,506   Comerica, Inc.   7,714,777
67,043   Cullen/Frost Bankers, Inc.   8,864,425
8,238   East West Bancorp, Inc.   553,099
17,409   Fifth Third Bancorp   556,392
10,731   First Citizens BancShares, Inc., Class A   8,557,221
3,916   First Republic Bank   511,234
44,368   Huntington Bancshares, Inc.   584,770
76,611   JPMorgan Chase & Co.   8,005,849
492,539   KeyCorp   7,890,475
92,288   M&T Bank Corp.   16,272,220
522,050   Old National Bancorp   8,598,163
7,367   Pinnacle Financial Partners, Inc.   597,464
55,146   PNC Financial Services Group (The), Inc.   8,239,915
225,668   Popular, Inc.   16,261,636
804,154   Regions Financial Corp.   16,139,371
3,410   Signature Bank   514,910
6,525   Silvergate Capital Corp., Class A (a)   491,659
1,463   SVB Financial Group (a)   491,246
216,958   Synovus Financial Corp.   8,138,095
186,016   Truist Financial Corp.   8,099,137
191,033   US Bancorp   7,702,451
12,636   Webster Financial Corp.   571,147
398,674   Wells Fargo & Co.   16,034,668
7,749   Western Alliance Bancorp   509,419
158,332   Zions Bancorp N.A.   8,052,766
        178,421,421
    Consumer Finance – 3.9%    
86,705   Discover Financial Services   7,883,219
    Thrifts & Mortgage Finance – 7.5%    
1,779,983   New York Community Bancorp, Inc.   15,183,255
    Total Investments – 99.7%   201,487,895
    (Cost $241,538,179)    
    Net Other Assets and Liabilities – 0.3%   550,560
    Net Assets – 100.0%   $202,038,455
    
(a) Non-income producing security.

Valuation Inputs
A summary of the inputs used to value the Fund’s investments as of September 30, 2022 is as follows (see Note 2A - Portfolio Valuation in the Notes to Financial Statements):
  Total
Value at
9/30/2022
Level 1
Quoted
Prices
Level 2
Significant
Observable
Inputs
Level 3
Significant
Unobservable
Inputs
Common Stocks* $201,487,895 $201,487,895 $ $
    
* See Portfolio of Investments for industry breakout.
 
See Notes to Financial Statements
Page 23

Table of Contents
First Trust Nasdaq Food & Beverage ETF (FTXG)
Portfolio of Investments
September 30, 2022 (Unaudited)
Shares   Description   Value
COMMON STOCKS – 99.9%
    Beverages – 26.9%    
20,201   Boston Beer (The) Co., Inc., Class A (a)   $6,538,054
93,664   Brown-Forman Corp., Class B   6,235,212
65,794   Celsius Holdings, Inc. (a)   5,966,200
580,349   Coca-Cola (The) Co.   32,511,151
145,551   Constellation Brands, Inc., Class A   33,430,154
939,493   Keurig Dr. Pepper, Inc.   33,652,639
1,347,304   Molson Coors Beverage Co., Class B   64,657,119
76,654   Monster Beverage Corp. (a)   6,665,832
207,894   PepsiCo, Inc.   33,940,774
        223,597,135
    Chemicals – 4.0%    
582,994   Corteva, Inc.   33,318,107
    Food & Staples Retailing – 0.7%    
222,374   US Foods Holding Corp. (a)   5,879,569
    Food Products – 67.7%    
407,483   Archer-Daniels-Midland Co.   32,782,007
279,065   Beyond Meat, Inc. (a)   3,954,351
722,263   Bunge Ltd.   59,637,256
1,346,630   Campbell Soup Co.   63,453,206
1,041,696   Conagra Brands, Inc.   33,990,540
89,524   Darling Ingredients, Inc. (a)   5,922,013
156,422   Freshpet, Inc. (a)   7,835,178
876,819   General Mills, Inc.   67,173,104
159,407   Hershey (The) Co.   35,144,461
712,280   Hormel Foods Corp.   32,366,003
1,545,017   Hostess Brands, Inc. (a)   35,906,195
255,826   J.M. Smucker (The) Co.   35,153,051
984,700   Kellogg Co.   68,594,202
182,061   Kraft Heinz (The) Co.   6,071,734
85,620   Lamb Weston Holdings, Inc.   6,625,276
80,991   McCormick & Co., Inc.   5,772,228
578,941   Mondelez International, Inc., Class A   31,743,335
475,106   Tyson Foods, Inc., Class A   31,323,739
        563,447,879
    Personal Products – 0.6%    
260,989   Herbalife Nutrition Ltd. (a)   5,191,071
    Total Investments – 99.9%   831,433,761
    (Cost $910,254,789)    
    Net Other Assets and Liabilities – 0.1%   548,435
    Net Assets – 100.0%   $831,982,196
    
(a) Non-income producing security.

Valuation Inputs
A summary of the inputs used to value the Fund’s investments as of September 30, 2022 is as follows (see Note 2A - Portfolio Valuation in the Notes to Financial Statements):
  Total
Value at
9/30/2022
Level 1
Quoted
Prices
Level 2
Significant
Observable
Inputs
Level 3
Significant
Unobservable
Inputs
Common Stocks* $831,433,761 $831,433,761 $ $
    
* See Portfolio of Investments for industry breakout.
 
Page 24
See Notes to Financial Statements

Table of Contents
First Trust Nasdaq Oil & Gas ETF (FTXN)
Portfolio of Investments
September 30, 2022 (Unaudited)
Shares   Description   Value
COMMON STOCKS – 99.9%
    Energy Equipment &
Services – 1.7%
   
114,200   Baker Hughes Co.   $2,393,632
132,261   ChampionX Corp.   2,588,348
95,742   Halliburton Co.   2,357,168
67,474   Helmerich & Payne, Inc.   2,494,514
163,249   NOV, Inc.   2,641,369
75,615   Schlumberger N.V.   2,714,578
796,854   Transocean Ltd. (a)   1,968,229
        17,157,838
    Oil, Gas & Consumable Fuels – 98.2%    
300,343   Antero Midstream Corp.   2,757,149
1,024,880   Antero Resources Corp. (a)   31,289,586
1,178,694   APA Corp.   40,299,548
67,777   Callon Petroleum Co. (a)   2,372,873
18,005   Cheniere Energy, Inc.   2,987,210
138,175   Chesapeake Energy Corp.   13,017,467
487,485   Chevron Corp.   70,036,970
42,934   Civitas Resources, Inc.   2,463,982
163,249   CNX Resources Corp. (a)   2,535,257
421,187   ConocoPhillips   43,104,278
910,685   Coterra Energy, Inc.   23,787,092
32,435   Denbury, Inc. (a)   2,797,843
618,482   Devon Energy Corp.   37,189,323
54,324   Diamondback Energy, Inc.   6,543,869
81,310   EOG Resources, Inc.   9,084,766
60,348   EQT Corp.   2,459,181
311,176   Equitrans Midstream Corp.   2,327,596
796,434   Exxon Mobil Corp.   69,536,653
23,880   Hess Corp.   2,602,681
705,014   HF Sinclair Corp.   37,957,954
2,516,307   Kinder Morgan, Inc.   41,871,348
6,520,327   Kosmos Energy Ltd. (a)   33,710,091
37,171   Laredo Petroleum, Inc. (a)   2,336,197
1,801,435   Marathon Oil Corp.   40,676,402
457,553   Marathon Petroleum Corp.   45,448,739
551,520   Matador Resources, Co.   26,980,358
365,582   Murphy Oil Corp.   12,857,519
1,298,557   Occidental Petroleum Corp.   79,796,328
164,949   ONEOK, Inc.   8,451,987
207,040   Ovintiv, Inc.   9,523,840
2,698,986   PBF Energy, Inc., Class A (a)   94,896,348
42,475   PDC Energy, Inc.   2,454,630
1,817,631   Permian Resources Corp. (a)   12,359,891
32,241   Phillips 66   2,602,494
168,984   Pioneer Natural Resources Co.   36,590,106
87,784   Range Resources Corp.   2,217,424
1,046,033   SM Energy Co.   39,341,301
385,129   Southwestern Energy Co. (a)   2,356,989
42,274   Targa Resources Corp.   2,550,813
721,150   Tellurian, Inc. (a)   1,723,548
379,785   Valero Energy Corp.   40,580,027
Shares   Description   Value
    Oil, Gas & Consumable
Fuels (Continued)
   
2,222,849   Williams (The) Cos., Inc.   $63,640,167
        1,008,117,825
    Total Investments – 99.9%   1,025,275,663
    (Cost $1,044,155,289)    
    Net Other Assets and Liabilities – 0.1%   771,111
    Net Assets – 100.0%   $1,026,046,774
    
(a) Non-income producing security.

Valuation Inputs
A summary of the inputs used to value the Fund’s investments as of September 30, 2022 is as follows (see Note 2A - Portfolio Valuation in the Notes to Financial Statements):
  Total
Value at
9/30/2022
Level 1
Quoted
Prices
Level 2
Significant
Observable
Inputs
Level 3
Significant
Unobservable
Inputs
Common Stocks* $1,025,275,663 $1,025,275,663 $ $
    
* See Portfolio of Investments for industry breakout.
 
See Notes to Financial Statements
Page 25

Table of Contents
First Trust Nasdaq Pharmaceuticals ETF (FTXH)
Portfolio of Investments
September 30, 2022 (Unaudited)
Shares   Description   Value
COMMON STOCKS – 99.9%
    Biotechnology – 45.7%    
11,076   AbbVie, Inc.   $1,486,510
22,471   Alkermes PLC (a)   501,777
12,395   Amgen, Inc.   2,793,833
5,963   BioMarin Pharmaceutical, Inc. (a)   505,484
7,264   Blueprint Medicines Corp. (a)   478,625
22,143   Emergent BioSolutions, Inc. (a)   464,782
46,928   Gilead Sciences, Inc.   2,894,988
8,983   Horizon Therapeutics PLC (a)   555,958
12,509   Ionis Pharmaceuticals, Inc. (a)   553,273
276,814   Ironwood Pharmaceuticals, Inc. (a)   2,867,793
3,447   Seagen, Inc. (a)   471,653
6,572   United Therapeutics Corp. (a)   1,376,045
5,286   Vertex Pharmaceuticals, Inc. (a)   1,530,508
        16,481,229
    Health Care Providers &
Services – 3.9%
   
21,059   Cardinal Health, Inc.   1,404,214
    Pharmaceuticals – 50.3%    
44,185   Bristol-Myers Squibb Co.   3,141,112
6,044   Catalent, Inc. (a)   437,344
20,599   Corcept Therapeutics, Inc. (a)   528,158
35,154   Elanco Animal Health, Inc. (a)   436,261
4,944   Eli Lilly & Co.   1,598,642
3,427   Jazz Pharmaceuticals PLC (a)   456,785
18,461   Johnson & Johnson   3,015,789
17,447   Merck & Co., Inc.   1,502,536
52,200   Organon & Co.   1,221,480
10,135   Pacira BioSciences, Inc. (a)   539,081
14,214   Perrigo Co. PLC   506,871
32,926   Pfizer, Inc.   1,440,842
29,444   Prestige Consumer Healthcare, Inc. (a)   1,467,195
155,943   Viatris, Inc.   1,328,634
3,398   Zoetis, Inc.   503,889
        18,124,619
    Total Investments – 99.9%   36,010,062
    (Cost $39,883,862)    
    Net Other Assets and Liabilities – 0.1%   25,513
    Net Assets – 100.0%   $36,035,575
    
(a) Non-income producing security.

Valuation Inputs
A summary of the inputs used to value the Fund’s investments as of September 30, 2022 is as follows (see Note 2A - Portfolio Valuation in the Notes to Financial Statements):
  Total
Value at
9/30/2022
Level 1
Quoted
Prices
Level 2
Significant
Observable
Inputs
Level 3
Significant
Unobservable
Inputs
Common Stocks* $36,010,062 $36,010,062 $ $
    
* See Portfolio of Investments for industry breakout.
 
Page 26
See Notes to Financial Statements

Table of Contents
First Trust S-Network E-Commerce ETF (ISHP)
Portfolio of Investments
September 30, 2022 (Unaudited)
Shares   Description   Value
COMMON STOCKS – 98.2%
    Air Freight & Logistics – 4.5%    
2,264   Deutsche Post AG (a)   $68,236
361   FedEx Corp.   53,598
449   United Parcel Service, Inc., Class B   72,531
        194,365
    Banks – 1.1%    
3,421   KakoaBank Corp. (a) (b)   47,390
    Commercial Services &
Supplies – 1.8%
   
726   Copart, Inc. (b)   77,246
    Consumer Finance – 0.9%    
14,518   Lufax Holding Ltd., ADR   36,876
    Entertainment – 1.4%    
1,093   Sea Ltd., ADR (b)   61,263
    Food & Staples Retailing – 2.0%    
667   Walmart, Inc.   86,510
    Hotels, Restaurants &
Leisure – 7.8%
   
858   Airbnb, Inc., Class A (b)   90,124
47   Booking Holdings, Inc. (b)   77,231
865   Expedia Group, Inc. (b)   81,042
3,140   Trip.com Group Ltd., ADR (b)   85,753
        334,150
    Interactive Media & Services – 20.6%    
704   Alphabet, Inc., Class A (b)   67,338
11,930   Auto Trader Group PLC (a) (c) (d)   67,656
541   Baidu, Inc., ADR (b)   63,562
1,045   IAC, Inc. (b)   57,872
3,079   Kanzhun Ltd., ADR (b)   51,974
486   Meta Platforms, Inc., Class A (b)   65,940
443   NAVER Corp. (a)   59,015
4,126   Pinterest, Inc., Class A (b)   96,136
999   REA Group Ltd. (a)   72,714
11,670   Rightmove PLC (a)   62,258
5,538   Snap, Inc., Class A (b)   54,383
2,156   Twitter, Inc. (b)   94,519
6,796   Yandex N.V., Class A (a) (b) (e) (f)   3,222
26,200   Z Holdings Corp. (a)   69,447
        886,036
    Internet & Direct Marketing
Retail – 21.2%
   
683   Alibaba Group Holding Ltd., ADR (b)   54,633
117,334   Alibaba Health Information Technology Ltd. (a) (b)   53,448
Shares   Description   Value
    Internet & Direct Marketing
Retail (Continued)
   
719   Amazon.com, Inc. (b)   $81,247
5,162   Coupang, Inc. (b)   86,051
2,118   Delivery Hero SE (a) (b) (c) (d)   77,365
1,100   DoorDash, Inc., Class A (b)   54,395
1,908   eBay, Inc.   70,233
10,206   JD Health International, Inc. (a) (b) (c) (d)   58,137
2,651   JD.com, Inc, Class A (a)   66,880
3,407   Meituan, Class B (a) (b) (c) (d)   71,603
116   MercadoLibre, Inc. (b)   96,022
1,344   Pinduoduo, Inc., ADR (b)   84,107
1,149   Prosus N.V. (a)   59,779
        913,900
    IT Services – 13.8%    
57   Adyen N.V. (a) (b) (c) (d)   71,088
1,218   Block, Inc. (b)   66,978
891   Fidelity National Information Services, Inc.   67,333
896   Fiserv, Inc. (b)   83,839
384   FleetCor Technologies, Inc. (b)   67,649
736   Global Payments, Inc.   79,525
1,114   PayPal Holdings, Inc. (b)   95,882
2,367   Shopify, Inc., Class A (b)   63,767
        596,061
    Marine – 1.5%    
35   AP Moller - Maersk A.S., Class B (a)   63,603
    Multiline Retail – 1.4%    
1,129   Next PLC (a)   59,923
    Professional Services – 2.2%    
1,356   CoStar Group, Inc. (b)   94,445
    Real Estate Management &
Development – 3.6%
   
4,957   KE Holdings, Inc., ADR (b)   86,847
2,348   Zillow Group, Inc., Class C (b)   67,176
        154,023
    Road & Rail – 5.9%    
738   Canadian National Railway Co.   79,701
3,677   Uber Technologies, Inc. (b)   97,441
393   Union Pacific Corp.   76,564
        253,706
    Specialty Retail – 4.9%    
1,180   Best Buy Co., Inc.   74,741
881   CarMax, Inc. (b)   58,164
654   Williams-Sonoma, Inc.   77,074
        209,979
 
See Notes to Financial Statements
Page 27

Table of Contents
First Trust S-Network E-Commerce ETF (ISHP)
Portfolio of Investments (Continued)
September 30, 2022 (Unaudited)
Shares   Description   Value
COMMON STOCKS (Continued)
    Textiles, Apparel & Luxury
Goods – 1.9%
   
288   Lululemon Athletica, Inc. (b)   $80,513
    Trading Companies &
Distributors – 1.7%
   
4,900   MonotaRO Co., Ltd. (a)   75,190
    Total Common Stocks   4,225,179
    (Cost $6,497,155)    
REAL ESTATE INVESTMENT TRUSTS – 1.6%
    Equity Real Estate Investment
Trusts – 1.6%
   
682   Prologis, Inc.   69,291
    (Cost $105,008)    
    Total Investments – 99.8%   4,294,470
    (Cost $6,602,163)    
    Net Other Assets and Liabilities – 0.2%   9,763
    Net Assets – 100.0%   $4,304,233
    
(a) This security is fair valued by the Advisor’s Pricing Committee in accordance with procedures approved by the Trust’s Board of Trustees and in accordance with provisions of the Investment Company Act of 1940 and rules thereunder, as amended. At September 30, 2022, securities noted as such are valued at $1,106,954 or 25.7% of net assets. Certain of these securities are fair valued using a factor provided by a third-party pricing service due to the change in value between the foreign markets’ close and the New York Stock Exchange close exceeding a certain threshold. On days when this threshold is not exceeded, these securities are typically valued at the last sale price on the exchange on which they are principally traded.
(b) Non-income producing security.
(c) This security may be resold to qualified foreign investors and foreign institutional buyers under Regulation S of the Securities Act of 1933, as amended (the “1933 Act”).
(d) This security is exempt from registration upon resale under Rule 144A of the 1933 Act and may be resold in transactions exempt from registration, normally to qualified institutional buyers. This security is not restricted on the foreign exchange where it trades freely without any additional registration. As such, it does not require the additional disclosure required of restricted securities.
(e) Pursuant to procedures adopted by the Trust’s Board of Trustees, this security has been determined to be illiquid by the Advisor.
(f) This security’s value was determined using significant unobservable inputs (see Note 2A – Portfolio Valuation in the Notes to Financial Statements).
    
ADR American Depositary Receipt
Currency Exposure
Diversification
% of Total
Investments
United States Dollar 72.4%
Euro 6.4
Hong Kong Dollar 5.8
British Pound Sterling 4.4
Japanese Yen 3.4
South Korean Won 2.5
Canadian Dollar 1.9
Australian Dollar 1.7
Danish Krone 1.5
Total 100.0%

Valuation Inputs
A summary of the inputs used to value the Fund’s investments as of September 30, 2022 is as follows (see Note 2A - Portfolio Valuation in the Notes to Financial Statements):
  Total
Value at
9/30/2022
Level 1
Quoted
Prices
Level 2
Significant
Observable
Inputs
Level 3
Significant
Unobservable
Inputs
Common Stocks:        
Air Freight & Logistics $194,365 $126,129 $68,236 $
Banks 47,390 47,390
Interactive Media & Services 886,036 551,724 331,090 3,222
Internet & Direct Marketing Retail 913,900 526,688 387,212
IT Services 596,061 524,973 71,088
Marine 63,603 63,603
Multiline Retail 59,923 59,923
Trading Companies & Distributors 75,190 75,190
Other Industry Categories* 1,388,711 1,388,711
Real Estate Investment Trusts* 69,291 69,291
Total Investments $4,294,470 $3,187,516 $1,103,732 $3,222
    
* See Portfolio of Investments for industry breakout.
Level 3 Common Stocks are fair valued by the Advisor’s Pricing Committee and are footnoted in the Portfolio of Investments. The Level 3 Common Stocks values are based on unobservable and non-quantitative inputs.
 
Page 28
See Notes to Financial Statements

Table of Contents
First Trust Nasdaq Semiconductor ETF (FTXL)
Portfolio of Investments
September 30, 2022 (Unaudited)
Shares   Description   Value
COMMON STOCKS – 99.9%
    Electronic Equipment,
Instruments & Components – 5.0%
   
63,631   Coherent Corp. (a)   $2,217,540
12,635   IPG Photonics Corp. (a)   1,065,762
        3,283,302
    Life Sciences Tools &
Services – 1.4%
   
21,715   Azenta, Inc.   930,705
    Semiconductors &
Semiconductor Equipment – 93.5%
   
13,487   Advanced Micro Devices, Inc. (a)   854,536
16,862   Ambarella, Inc. (a)   947,307
19,833   Analog Devices, Inc.   2,763,530
28,243   Applied Materials, Inc.   2,313,949
12,043   Broadcom, Inc.   5,347,212
12,064   Entegris, Inc.   1,001,553
188,301   Intel Corp.   4,852,517
8,733   KLA Corp.   2,642,868
2,766   Lam Research Corp.   1,012,356
21,236   Lattice Semiconductor Corp. (a)   1,045,024
24,447   Marvell Technology, Inc.   1,049,021
46,058   Microchip Technology, Inc.   2,810,920
53,163   Micron Technology, Inc.   2,663,466
2,526   Monolithic Power Systems, Inc.   917,948
7,583   NVIDIA Corp.   920,500
18,260   NXP Semiconductors N.V.   2,693,533
87,401   ON Semiconductor Corp. (a)   5,447,704
16,002   Power Integrations, Inc.   1,029,249
33,474   Qorvo, Inc. (a)   2,658,170
22,721   QUALCOMM, Inc.   2,567,019
9,133   Silicon Laboratories, Inc. (a)   1,127,378
10,757   SiTime Corp. (a)   846,899
60,990   Skyworks Solutions, Inc.   5,200,617
9,901   Synaptics, Inc. (a)   980,298
13,523   Teradyne, Inc.   1,016,254
36,381   Texas Instruments, Inc.   5,631,051
10,087   Wolfspeed, Inc. (a)   1,042,592
        61,383,471
    Total Investments – 99.9%   65,597,478
    (Cost $88,661,939)    
    Net Other Assets and Liabilities – 0.1%   46,310
    Net Assets – 100.0%   $65,643,788
    
(a) Non-income producing security.

Valuation Inputs
A summary of the inputs used to value the Fund’s investments as of September 30, 2022 is as follows (see Note 2A - Portfolio Valuation in the Notes to Financial Statements):
  Total
Value at
9/30/2022
Level 1
Quoted
Prices
Level 2
Significant
Observable
Inputs
Level 3
Significant
Unobservable
Inputs
Common Stocks* $65,597,478 $65,597,478 $ $
    
* See Portfolio of Investments for industry breakout.
 
See Notes to Financial Statements
Page 29

Table of Contents
First Trust Nasdaq Transportation ETF (FTXR)
Portfolio of Investments
September 30, 2022 (Unaudited)
Shares   Description   Value
COMMON STOCKS – 99.9%
    Air Freight & Logistics – 19.2%    
56,927   CH Robinson Worldwide, Inc.   $5,482,639
31,579   Expeditors International of Washington, Inc.   2,788,742
15,413   FedEx Corp.   2,288,368
16,704   United Parcel Service, Inc., Class B   2,698,364
        13,258,113
    Airlines – 9.1%    
74,590   Alaska Air Group, Inc. (a)   2,920,199
57,723   American Airlines Group, Inc. (a)   694,985
24,133   Delta Air Lines, Inc. (a)   677,172
96,254   JetBlue Airways Corp. (a)   638,164
20,431   Southwest Airlines Co. (a)   630,092
21,417   United Airlines Holdings, Inc. (a)   696,695
        6,257,307
    Auto Components – 10.1%    
8,025   Aptiv PLC (a)   627,635
231,584   Goodyear Tire & Rubber (The) Co. (a)   2,336,682
23,436   Lear Corp.   2,805,055
86,986   Luminar Technologies, Inc. (a) (b)   633,693
67,980   QuantumScape Corp. (a) (b)   571,712
        6,974,777
    Automobiles – 12.8%    
83,037   Fisker, Inc. (a) (b)   626,929
426,394   Ford Motor Co.   4,775,613
85,033   General Motors Co.   2,728,709
2,721   Tesla, Inc. (a)   721,745
        8,852,996
    Distributors – 4.2%    
61,051   LKQ Corp.   2,878,555
    Machinery – 9.7%    
139,892   Nikola Corp. (a) (b)   492,420
74,257   PACCAR, Inc.   6,214,568
        6,706,988
    Road & Rail – 30.4%    
205,306   CSX Corp.   5,469,352
18,671   JB Hunt Transport Services, Inc.   2,920,518
13,364   Norfolk Southern Corp.   2,801,763
2,763   Old Dominion Freight Line, Inc.   687,351
3,625   Saia, Inc. (a)   688,750