Document


President’s Letter			2
Mid Cap Growth Impact ETF
Performance			3
Portfolio Commentary			4
Fund Characteristics			6
Sustainable Equity ETF
Performance			7
Portfolio Commentary			8
Fund Characteristics			10
Sustainable Growth ETF
Performance			11
Portfolio Commentary			12
Fund Characteristics			14
Shareholder Fee Examples			15
Schedules of Investments			16
Statements of Assets and Liabilities			26
Statements of Operations			28
Statements of Changes in Net Assets			30
Notes to Financial Statements			32
Financial Highlights			37
Report of Independent Registered Public Accounting Firm			40
Management			42
Approval of Management Agreement			44

Liquidity Risk Management Program			48
Additional Information			49

Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.

Market price is determined using the bid/ask midpoint at 4:00 p.m. Eastern time, when the net asset value (NAV) is typically calculated. Market performance does not represent the returns you would receive if you traded shares at other times. NAV prices are used to calculate market price performance prior to the date when the fund first traded on the NYSE Arca, Inc.

The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.

Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-6488 or visit americancenturyetfs.com. For additional information about the funds, please consult the prospectus.

American Century Mid Cap Growth Impact ETF is an actively managed fund that seeks long-term capital growth. The portfolio managers look for stocks of medium-capitalization companies they believe will increase in value over time, using proprietary fundamental research. The initial research process begins by analyzing themes aligned with the U.N. Sustainable Development Goals (SDG) to identify companies that generate, or could generate, social and environmental impact alongside a financial return. We make our investment decisions based primarily on our analysis of individual companies, rather than on broad economic forecasts. We generate an impact thesis to explain current or projected SDG alignment in combination with each security’s fundamental growth profile.

The fund returned -27.39% on a market price basis for the 12-month period ended August 31, 2022. On a net asset value (NAV) basis, the fund returned -27.33%. For the same time period, the Russell Midcap Growth Index, the fund’s benchmark, returned -26.69%. The fund’s NAV and market price returns reflect fees and operating expenses, while the index return does not.

Other detractors included DocuSign. The company develops software for online signatures and document management. DocuSign was a beneficiary of the pandemic-driven work-from-home environment but offered weak guidance as that tailwind subsides. We believe in the long-term adoption of e-signature and a more efficient document workflow that DocuSign offers. The small- and micro-merchant digital payments company Block (formerly Square) suffered during the growth sell-off as initially rising interest rates and later recessionary fears weighed on the stock. Additionally, Block’s focus on blockchain technology—which enables cryptocurrencies—hurt as crypto prices fell. Surging interest rates and investors’ move away from riskier assets because of the Russia-Ukraine war led fast-growth and expensive technology stocks such as IT services company Twilio to underperform. Block and Twilio were eliminated. Natera hampered performance. The stock of this genetic testing company fell amid allegations of marketing impropriety. We eliminated our position as Natera no longer aligned with our mandate for proper governance.

Stock selection in the software industry led performance in information technology, driven by Palo Alto Networks. Over the past three years this cybersecurity software provider has transformed into a cloud-based platform of next-generation cybersecurity products. On top of a very strong environment for its products, Palo Alto said it expects greater free cash flow generation now that the heavy lift in its transformation is over. Cadence Design Systems sells software to help build semiconductor chips. Semiconductors have unprecedented tailwinds enabling themes like the cloud, 5G, internet of things and ultimately the metaverse. Cadence benefited from more customers and more usage.

Enphase Energy makes inverters to efficiently convert power from solar cells into usable electricity for the home. Demand for solar is high now that prices have been cut by 90% the past decade. After a period of revenue constrained by supply chain issues, Enphase experienced accelerating growth as the company addressed the supply challenges. Keysight Technologies sells measurement tools for high-frequency applications such as 5G and in automobiles. Keysight benefited from multiple tailwinds as complex communications capabilities are being added to an increasing set of applications from cars to consumer devices.

Elsewhere, Sarepta Therapeutics was a key contributor. This biopharmaceutical company benefited from investor enthusiasm about its pipeline of burgeoning gene therapies to treat rare diseases. Materials in general benefited from greater demand and firmer pricing due to global supply chain disruptions. Albemarle was a top contributor on demand for lithium, a key ingredient of batteries for electric vehicles.

Our process uses fundamental analysis aimed at identifying mid-capitalization companies producing attractive, sustained earnings growth. We seek to reduce unintended, nonfundamental risks and align the portfolio with fundamental, company-specific risks that we believe will be rewarded over time. As a result of this approach, our sector and industry allocations reflect where we are finding opportunities at a given time. We see longer-term opportunities in companies seeking to achieve the U.N. SDG with key impact themes of a greener planet; innovation, efficiency and education driven by technology; and improving health care outcomes across various sectors of our portfolio.

A strategy that considers the United Nations Sustainable Development Goals (SDG) criteria may limit the investment opportunities available to a portfolio. Therefore, the portfolio may underperform or perform differently than other portfolios that do not have an SDG investment focus. A portfolio’s SDG investment focus may also result in the portfolio investing in securities or industry sectors that perform differently or maintain a different risk profile than the market generally or compared to underlying holdings that are not screened for SDG standards.


AUGUST 31, 2022

Mid Cap Growth Impact ETF
Types of Investments in Portfolio			% of net assets
Common Stocks			97.3%
Short-Term Investments			3.2%
Other Assets and Liabilities			(0.5)%

Top Five Industries			% of net assets
Software			17.9%
Semiconductors and Semiconductor Equipment			14.6%
Hotels, Restaurants and Leisure			9.2%
Chemicals			7.5%
Biotechnology			7.2%

American Century Sustainable Equity ETF is an actively managed fund that seeks long-term capital growth. We seek to invest in larger U.S. companies demonstrating both improving business fundamentals and sustainable corporate behaviors in pursuit of long-term financial returns and a stronger environmental, social and governance (ESG) profile than the S&P 500 Index. As opposed to avoiding certain sectors entirely, we seek to invest in the most attractive companies within all sectors. A broad investment universe provides investors with both an attractive ESG profile and the potential for positive risk-adjusted returns over time. We construct our portfolio to intentionally acquire stock-specific risk aligned with our financial and sustainability research, while minimizing relative exposures related to sectors and common factor risks, such as market-capitalization size, volatility and momentum.

The fund returned -14.10% on a market price basis for its fiscal year ended August 31, 2022. On a net asset value (NAV) basis, the fund returned -14.03%. For the same time period, the S&P 500 Index, the fund’s benchmark, returned -11.23%. The fund’s NAV and market price returns reflect fees and operating expenses, while the index return does not.

Stock selection in the semiconductors and semiconductor equipment industry helped drive underperformance in information technology. Both chipmakers and semiconductor equipment manufacturers are being pressured by concerns that a slowdown in consumer spending will hamper demand for chips. ASML Holding, a Netherlands-based semiconductor capital equipment maker, was a significant industry detractor. Stock selection in the IT services industry also hurt performance in the sector. PayPal Holdings reported disappointing earnings largely due to declining eBay transactions. We eliminated PayPal. Underweighting Apple relative to the index hampered performance. The consumer electronics giant reported better-than-expected results, driven by iPhone sales.

Energy companies continued to benefit from rising oil and gas prices. Russia’s invasion of Ukraine, Europe’s energy supply concerns and slow production growth in the U.S. and from OPEC have kept energy markets volatile and in negative supply. We had lighter exposure to Exxon Mobil and Chevron than the benchmark, which hampered relative performance. Our underweight allocation to energy overall hampered relative performance, although a number of our holdings in the sector were top contributors, which helped offset some of the detraction. The portfolio was also underweight Tesla. The electric vehicle maker continued to outperform, exceeding production goals in the face of global supply chain disruptions and pandemic lockdowns in China.

Positioning in the communication services sector benefited performance. We were underweight two laggards, Facebook’s parent Meta Platforms and streaming video company Netflix. Meta has been hurt more by both Apple iOS platform changes and TikTok competition than other digital advertising platforms. Our underweight reflects our elimination of Meta during the first quarter of 2022. Netflix announced layoffs amid weak subscriber growth. An expected renormalization of subscriber growth following the early gains of the pandemic has not materialized. We also eliminated Netflix.

Some of the leading individual contributors to performance compared with the benchmark were energy companies ConocoPhillips and Schlumberger. This is consistent with our process, which seeks to identify companies we believe are ESG leaders within all sectors, rather than exclude certain sectors entirely. Our approach led us to overweight positions in these companies, which we believe have relatively more attractive financial and ESG characteristics than other energy companies. ConocoPhilllips was the fund’s top contributor, benefiting from the jump in fossil fuel prices. Rising energy prices also boosted oil field services companies such as Schlumberger. The company also benefited from a multiyear growth dynamic leading to strong cash flow growth. Schlumberger’s new energy division is focused on transitioning toward lower carbon energy solutions: geothermal, hydrogen, carbon capture and sequestration.

Elsewhere, Cigna was a top performer. Managed care companies such as Cigna were perceived as being relatively insulated from the inflationary environment. We think Cigna’s pharmacy benefit management division should also benefit from new biosimilar pharmaceutical launches in the coming years. NextEra Energy received a boost from an executive order delaying implementation of solar panel tariffs, which helped ease concerns that NextEra’s plans for renewable capacity expansion would be slowed.

Our process uses fundamental analysis aimed at identifying growing, large-capitalization companies demonstrating sustainable corporate behaviors. Rather than screen out certain industries or sectors, we seek to identify companies with attractive fundamental growth and ESG characteristics in their respective sectors. As a result of this approach, our sector and industry allocations reflect where we are finding opportunities at a given time.

Using our bottom-up analysis, we have found what we think are attractive positions in the industrials sector, led by building products and electrical equipment. Consumer staples was also modestly overweight due to positions in food and staples retailing and household products. Utilities was the largest underweight sector because many of the companies in the sector do not fit our process well.

A strategy or emphasis on environmental, social and governance factors (ESG) may limit the investment opportunities available to a portfolio. Therefore, the portfolio may underperform or perform differently than other portfolios that do not have an ESG investment focus. A portfolio’s ESG investment focus may also result in the portfolio investing in securities or industry sectors that perform differently or maintain a different risk profile than the market generally or compared to underlying holdings that are not screened for ESG standards.


AUGUST 31, 2022

Sustainable Equity ETF
Types of Investments in Portfolio			% of net assets
Common Stocks			99.5%
Short-Term Investments			0.4%
Other Assets and Liabilities			0.1%

Top Five Industries			% of net assets
Software			10.0%
Health Care Providers and Services			5.2%
Technology Hardware, Storage and Peripherals			5.0%
Interactive Media and Services			4.9%
Capital Markets			4.7%

American Century Sustainable Growth ETF is an actively managed fund that seeks capital appreciation. We seek to invest in larger U.S. companies demonstrating both improving business fundamentals and sustainable corporate behaviors in pursuit of long-term financial returns and a stronger environmental, social and governance (ESG) profile than the Russell 1000 Growth Index. As opposed to avoiding certain sectors entirely, we seek to invest in the most attractive companies within all sectors. A broad investment universe provides investors with both an attractive environmental, social and governance (ESG) profile and the potential for positive risk-adjusted returns over time. We construct our portfolio to intentionally acquire stock-specific risk aligned with our financial and sustainability research, while minimizing relative exposures related to sectors and common factor risks, such as market-capitalization size, volatility and momentum.

The fund returned -19.93% on a market price basis for the 12-month period ended August 31, 2022. On a net asset value (NAV) basis, the fund returned -19.93%. For the same period, the Russell 1000 Growth Index, the fund’s benchmark, returned -19.06%. The fund’s NAV and market price returns reflect fees and operating expenses, while the index return does not.

Stock selection in the semiconductors and semiconductor equipment industry helped drive underperformance in information technology. Both chipmakers and semiconductor equipment manufacturers are being pressured by concerns that a slowdown in consumer spending will hamper demand for chips. ASML Holding, a Netherlands-based semiconductor capital equipment maker, was a significant industry detractor. Stock selection in the IT services industry also hurt performance in the sector. PayPal Holdings reported disappointing earnings largely due to declining eBay transactions. We eliminated our holding. Software provider Adobe fell on expectations of slowing company spending on software as economic growth slows.

We were also hurt by lighter exposure than the benchmark in a trio of other stocks. Apple reported better-than-expected quarterly results, driven by iPhone sales. AbbVie, a large pharmaceutical company, benefited from investors looking for safer havens. We had no exposure to brick-and-mortar retailer Costco Wholesale, which recently reported membership renewals, its primary driver of profits, of more than 90%. Costco is also seen as recession-proof as consumers buy more bulk items to reduce costs.

Stock choices in the interactive media and services industry led relative performance in communication services. We had less exposure to the lagging Meta Platforms than the benchmark. Facebook’s parent company has been hurt more by both Apple iOS platform changes and TikTok competition than other digital advertising platforms. Underweighting Netflix benefited relative performance. The streaming video service announced layoffs amid weak subscriber growth. An expected renormalization of subscriber growth following the early gains of the pandemic has not materialized. We eliminated Meta Platforms and Netflix.

Stock selection in health care was also helpful. UnitedHealth Group was a key contributor. The health insurer reported solid earnings and modestly increased its earnings guidance. However, the stock’s outperformance for much of the period was driven more by its defensive profile and being more insulated from the impact of inflation and a stronger U.S. dollar. Denmark-based pharmaceutical company Novo Nordisk continued to benefit from strong sales and demand for its obesity drug. Vertex Pharmaceuticals dominates the cystic fibrosis market with no real prospects of

Using our bottom-up analysis, we have found attractive positions in several sectors, notably information technology. In particular, we invested in attractive companies in the software, electronic equipment, instruments and components and semiconductors and semiconductor equipment industries. We have also found opportunities in health care, especially pharmaceuticals.


AUGUST 31, 2022

Sustainable Growth ETF
Types of Investments in Portfolio			% of net assets
Common Stocks			99.6%
Short-Term Investments			0.3%
Other Assets and Liabilities			0.1%

Top Five Industries			% of net assets
Software			19.7%
Technology Hardware, Storage and Peripherals			10.5%
Semiconductors and Semiconductor Equipment			7.6%
Interactive Media and Services			6.6%
IT Services			6.6%

Fund shareholders may incur two types of costs: (1) transaction costs, including brokerage commissions paid on purchases and sales of fund shares; and (2) ongoing costs, including management fees and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other funds.

The table provides information about actual account values and actual expenses for each fund. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the fund you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as brokerage commissions paid on purchases and sales of fund shares. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.


	Beginning Account Value 3/1/22	Ending Account Value 8/31/22	Expenses Paid During Period(1) 3/1/22 - 8/31/22	Annualized Expense Ratio(1)
Mid Cap Growth Impact ETF
Actual	$1,000	$907.90	$2.16	0.45%
Hypothetical	$1,000	$1,022.94	$2.29	0.45%
Sustainable Equity ETF
Actual	$1,000	$896.50	$1.86	0.39%
Hypothetical	$1,000	$1,023.24	$1.99	0.39%
Sustainable Growth ETF
Actual	$1,000	$860.00	$1.83	0.39%
Hypothetical	$1,000	$1,023.24	$1.99	0.39%

(1)Expenses are equal to the fund's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 365, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.


Mid Cap Growth Impact ETF
	Shares	Value
COMMON STOCKS — 97.3%
Aerospace and Defense — 1.2%
CAE, Inc.(1)	15,358	$	280,437
Auto Components — 3.4%
Aptiv PLC(1)	8,784	820,689
Biotechnology — 7.2%
Alnylam Pharmaceuticals, Inc.(1)	894	184,763
Horizon Therapeutics PLC(1)	6,376	377,523
Sarepta Therapeutics, Inc.(1)	7,009	766,644
Seagen, Inc.(1)	2,488	383,874
		1,712,804
Building Products — 5.9%
Trane Technologies PLC	6,338	976,496
Zurn Elkay Water Solutions Corp.	15,490	427,214
		1,403,710
Capital Markets — 3.6%
MSCI, Inc.	1,896	851,759
Chemicals — 7.5%
Albemarle Corp.	818	219,192
Avient Corp.	14,012	614,146
Element Solutions, Inc.	50,439	941,696
		1,775,034
Electrical Equipment — 3.4%
Generac Holdings, Inc.(1)	2,524	556,315
Plug Power, Inc.(1)(2)	8,609	241,396
		797,711
Electronic Equipment, Instruments and Components — 5.1%
Keysight Technologies, Inc.(1)	7,444	1,219,997
Health Care Equipment and Supplies — 3.1%
DexCom, Inc.(1)	8,858	728,216
Health Care Technology — 3.2%
Veeva Systems, Inc., Class A(1)	3,875	772,365
Hotels, Restaurants and Leisure — 9.2%
Airbnb, Inc., Class A(1)	7,866	889,802
Chipotle Mexican Grill, Inc.(1)	814	1,299,795
		2,189,597
Life Sciences Tools and Services — 5.4%
Bio-Techne Corp.	2,094	694,810
IQVIA Holdings, Inc.(1)	2,816	598,851
		1,293,661
Oil, Gas and Consumable Fuels — 2.4%
Excelerate Energy, Inc., Class A	22,237	571,046
Professional Services — 3.3%
Jacobs Solutions, Inc.	6,246	778,127
Road and Rail — 0.9%
Lyft, Inc., Class A(1)	14,999	220,935
Semiconductors and Semiconductor Equipment — 14.6%
Enphase Energy, Inc.(1)	6,397	1,832,357


Mid Cap Growth Impact ETF
	Shares	Value
Marvell Technology, Inc.	18,045	$	844,867
Monolithic Power Systems, Inc.	1,745	790,799
		3,468,023
Software — 17.9%
Cadence Design Systems, Inc.(1)	9,305	1,616,930
DocuSign, Inc.(1)	5,777	336,337
Manhattan Associates, Inc.(1)	8,491	1,199,438
Palo Alto Networks, Inc.(1)	1,975	1,099,700
		4,252,405
TOTAL COMMON STOCKS (Cost $25,515,834)		23,136,516
SHORT-TERM INVESTMENTS — 3.2%
Money Market Funds — 3.2%
State Street Institutional U.S. Government Money Market Fund, Premier Class	645,638	645,638
State Street Navigator Securities Lending Government Money Market Portfolio(3)	123,740	123,740
TOTAL SHORT-TERM INVESTMENTS (Cost $769,378)		769,378
TOTAL INVESTMENT SECURITIES — 100.5% (Cost $26,285,212)		23,905,894
OTHER ASSETS AND LIABILITIES — (0.5)%		(126,566)
TOTAL NET ASSETS — 100.0%		$	23,779,328


Sustainable Equity ETF
	Shares	Value
COMMON STOCKS — 99.5%
Aerospace and Defense — 1.2%
Lockheed Martin Corp.	2,931	$	1,231,342
Air Freight and Logistics — 1.3%
United Parcel Service, Inc., Class B	6,909	1,343,870
Auto Components — 0.7%
Aptiv PLC(1)	8,004	747,814
Automobiles — 1.7%
Tesla, Inc.(1)	6,434	1,773,275
Banks — 3.1%
Bank of America Corp.	9,899	332,705
JPMorgan Chase & Co.	12,533	1,425,378
Regions Financial Corp.	67,559	1,464,004
		3,222,087
Beverages — 1.8%
PepsiCo, Inc.	10,726	1,847,768
Biotechnology — 2.0%
AbbVie, Inc.	8,834	1,187,820
Amgen, Inc.	1,724	414,277
Vertex Pharmaceuticals, Inc.(1)	1,672	471,103
		2,073,200
Building Products — 1.6%
Johnson Controls International PLC	20,334	1,100,883
Masco Corp.	10,435	530,828
		1,631,711
Capital Markets — 4.7%
Ameriprise Financial, Inc.	2,645	708,886
BlackRock, Inc.	1,516	1,010,247
Intercontinental Exchange, Inc.	5,275	531,984
Morgan Stanley	20,130	1,715,479
S&P Global, Inc.	2,867	1,009,700
		4,976,296
Chemicals — 2.3%
Air Products and Chemicals, Inc.	1,852	467,537
Ecolab, Inc.	2,973	487,066
Linde PLC	4,610	1,303,985
Sherwin-Williams Co.	696	161,542
		2,420,130
Communications Equipment — 1.9%
Cisco Systems, Inc.	43,373	1,939,641
Consumer Finance — 0.5%
American Express Co.	3,633	552,216
Containers and Packaging — 0.6%
Ball Corp.	10,554	589,019
Diversified Telecommunication Services — 1.1%
Verizon Communications, Inc.	27,885	1,165,872
Electric Utilities — 2.2%
NextEra Energy, Inc.	27,182	2,312,101
Electrical Equipment — 1.3%
Eaton Corp. PLC	5,358	732,117


Sustainable Equity ETF
	Shares	Value
Generac Holdings, Inc.(1)	1,278	$	281,684
Rockwell Automation, Inc.	1,601	379,341
		1,393,142
Electronic Equipment, Instruments and Components — 2.1%
CDW Corp.	5,806	991,084
Cognex Corp.	4,470	188,232
Keysight Technologies, Inc.(1)	6,126	1,003,990
		2,183,306
Energy Equipment and Services — 2.1%
Schlumberger NV	57,141	2,179,929
Entertainment — 1.3%
Electronic Arts, Inc.	3,542	449,374
Walt Disney Co.(1)	8,155	914,012
		1,363,386
Equity Real Estate Investment Trusts (REITs) — 2.3%
Prologis, Inc.	19,453	2,422,093
Food and Staples Retailing — 2.6%
Costco Wholesale Corp.	1,415	738,772
Kroger Co.	14,977	717,997
Sysco Corp.	15,554	1,278,850
		2,735,619
Food Products — 0.8%
Mondelez International, Inc., Class A	13,533	837,151
Vital Farms, Inc.(1)	3,757	48,653
		885,804
Health Care Equipment and Supplies — 1.3%
Edwards Lifesciences Corp.(1)	10,948	986,415
Medtronic PLC	1,819	159,926
ResMed, Inc.	1,023	224,978
		1,371,319
Health Care Providers and Services — 5.2%
Cigna Corp.	5,909	1,674,906
CVS Health Corp.	12,726	1,249,057
Humana, Inc.	1,159	558,383
UnitedHealth Group, Inc.	3,811	1,979,167
		5,461,513
Hotels, Restaurants and Leisure — 1.1%
Booking Holdings, Inc.(1)	349	654,658
Chipotle Mexican Grill, Inc.(1)	163	260,278
Expedia Group, Inc.(1)	2,781	285,470
		1,200,406
Household Products — 1.6%
Colgate-Palmolive Co.	6,348	496,477
Procter & Gamble Co.	8,789	1,212,355
		1,708,832
Industrial Conglomerates — 0.9%
Honeywell International, Inc.	5,037	953,756
Insurance — 2.1%
Marsh & McLennan Cos., Inc.	4,467	720,840
Prudential Financial, Inc.	7,964	762,553
Travelers Cos., Inc.	4,372	706,690
		2,190,083


Sustainable Equity ETF
	Shares	Value
Interactive Media and Services — 4.9%
Alphabet, Inc., Class A(1)	47,020	$	5,088,504
Internet and Direct Marketing Retail — 3.2%
Amazon.com, Inc.(1)	26,721	3,387,421
IT Services — 4.2%
Accenture PLC, Class A	4,297	1,239,513
Mastercard, Inc., Class A	3,850	1,248,824
Visa, Inc., Class A	9,470	1,881,784
		4,370,121
Life Sciences Tools and Services — 2.1%
Agilent Technologies, Inc.	8,167	1,047,418
Thermo Fisher Scientific, Inc.	2,114	1,152,806
		2,200,224
Machinery — 2.0%
Cummins, Inc.	3,899	839,727
Deere & Co.	1,160	423,690
Parker-Hannifin Corp.	1,377	364,905
Xylem, Inc.	5,038	458,962
		2,087,284
Media — 0.4%
Comcast Corp., Class A	11,249	407,101
Multiline Retail — 0.4%
Target Corp.	2,673	428,589
Oil, Gas and Consumable Fuels — 2.5%
ConocoPhillips	23,927	2,618,810
Personal Products — 0.3%
Estee Lauder Cos., Inc., Class A	1,152	293,046
Pharmaceuticals — 3.7%
Bristol-Myers Squibb Co.	18,902	1,274,184
Merck & Co., Inc.	13,195	1,126,325
Novo Nordisk A/S, ADR	6,202	658,032
Zoetis, Inc.	5,460	854,654
		3,913,195
Road and Rail — 1.3%
Norfolk Southern Corp.	2,691	654,263
Uber Technologies, Inc.(1)	6,880	197,868
Union Pacific Corp.	2,490	559,030
		1,411,161
Semiconductors and Semiconductor Equipment — 4.3%
Advanced Micro Devices, Inc.(1)	7,106	603,086
Analog Devices, Inc.	7,459	1,130,263
Applied Materials, Inc.	7,584	713,427
ASML Holding NV, NY Shares	1,232	603,606
NVIDIA Corp.	9,815	1,481,476
		4,531,858
Software — 10.0%
Adobe, Inc.(1)	1,471	549,330
Cadence Design Systems, Inc.(1)	2,855	496,113
Microsoft Corp.	31,947	8,353,182
Salesforce, Inc.(1)	4,105	640,873
ServiceNow, Inc.(1)	621	269,899


Sustainable Equity ETF
	Shares	Value
Workday, Inc., Class A(1)	1,260	$	207,346
		10,516,743
Specialty Retail — 2.9%
Home Depot, Inc.	6,158	1,776,090
TJX Cos., Inc.	14,347	894,536
Tractor Supply Co.	1,776	328,826
		2,999,452
Technology Hardware, Storage and Peripherals — 5.0%
Apple, Inc.	33,286	5,233,225
Textiles, Apparel and Luxury Goods — 0.9%
Deckers Outdoor Corp.(1)	1,086	349,225
NIKE, Inc., Class B	5,753	612,407
		961,632
TOTAL COMMON STOCKS (Cost $104,333,323)		104,323,896
SHORT-TERM INVESTMENTS — 0.4%
Money Market Funds — 0.4%
State Street Institutional U.S. Government Money Market Fund, Premier Class (Cost $368,997)	368,997	368,997
TOTAL INVESTMENT SECURITIES — 99.9% (Cost $104,702,320)		104,692,893
OTHER ASSETS AND LIABILITIES — 0.1%		107,241
TOTAL NET ASSETS — 100.0%		$	104,800,134


Sustainable Growth ETF
	Shares	Value
COMMON STOCKS — 99.6%
Aerospace and Defense — 0.5%
Lockheed Martin Corp.	85	$	35,709
Air Freight and Logistics — 0.9%
United Parcel Service, Inc., Class B	298	57,964
Auto Components — 0.9%
Aptiv PLC(1)	623	58,207
Automobiles — 3.4%
Tesla, Inc.(1)	801	220,764
Beverages — 3.0%
Coca-Cola Co.	1,331	82,136
PepsiCo, Inc.	663	114,215
		196,351
Biotechnology — 2.6%
AbbVie, Inc.	706	94,929
Vertex Pharmaceuticals, Inc.(1)	268	75,511
		170,440
Building Products — 2.1%
Johnson Controls International PLC	1,153	62,423
Masco Corp.	1,343	68,318
Trex Co., Inc.(1)	216	10,107
		140,848
Capital Markets — 0.6%
S&P Global, Inc.	108	38,035
Chemicals — 1.2%
Linde PLC	278	78,635
Commercial Services and Supplies — 0.2%
Copart, Inc.(1)	133	15,913
Communications Equipment — 0.4%
Cisco Systems, Inc.	660	29,515
Distributors — 0.2%
Pool Corp.	45	15,264
Electrical Equipment — 0.9%
Generac Holdings, Inc.(1)	67	14,767
Rockwell Automation, Inc.	186	44,071
		58,838
Electronic Equipment, Instruments and Components — 1.5%
CDW Corp.	199	33,969
Cognex Corp.	301	12,675
Keysight Technologies, Inc.(1)	301	49,331
		95,975
Energy Equipment and Services — 0.6%
Schlumberger NV	1,100	41,965
Entertainment — 1.4%
Electronic Arts, Inc.	296	37,554
Walt Disney Co.(1)	454	50,884
Warner Bros Discovery, Inc.(1)	387	5,124
		93,562
Equity Real Estate Investment Trusts (REITs) — 0.7%
Prologis, Inc.	381	47,438


Sustainable Growth ETF
	Shares	Value
Food and Staples Retailing — 0.2%
Kroger Co.	237	$	11,362
Food Products — 0.5%
Mondelez International, Inc., Class A	569	35,198
Health Care Equipment and Supplies — 2.2%
Align Technology, Inc.(1)	33	8,042
DexCom, Inc.(1)	180	14,798
Edwards Lifesciences Corp.(1)	617	55,592
IDEXX Laboratories, Inc.(1)	88	30,591
Inari Medical, Inc.(1)	53	3,675
Shockwave Medical, Inc.(1)	91	27,014
Tandem Diabetes Care, Inc.(1)	141	6,449
		146,161
Health Care Providers and Services — 3.6%
Cigna Corp.	249	70,579
UnitedHealth Group, Inc.	314	163,070
		233,649
Hotels, Restaurants and Leisure — 0.8%
Airbnb, Inc., Class A(1)	61	6,900
Chipotle Mexican Grill, Inc.(1)	16	25,549
Expedia Group, Inc.(1)	185	18,990
		51,439
Household Products — 1.1%
Procter & Gamble Co.	529	72,970
Interactive Media and Services — 6.6%
Alphabet, Inc., Class A(1)	3,980	430,716
Internet and Direct Marketing Retail — 6.3%
Amazon.com, Inc.(1)	3,094	392,226
eBay, Inc.	545	24,051
		416,277
IT Services — 6.6%
Accenture PLC, Class A	183	52,788
Mastercard, Inc., Class A	525	170,294
Okta, Inc.(1)	289	26,415
Snowflake, Inc., Class A(1)	65	11,762
Visa, Inc., Class A	850	168,903
		430,162
Leisure Products — 0.1%
YETI Holdings, Inc.(1)	238	8,780
Life Sciences Tools and Services — 1.5%
Agilent Technologies, Inc.	379	48,607
Illumina, Inc.(1)	128	25,810
West Pharmaceutical Services, Inc.	78	23,142
		97,559
Machinery — 1.3%
Deere & Co.	230	84,008
Multiline Retail — 0.4%
Nordstrom, Inc.	341	5,835
Target Corp.	113	18,118
		23,953


Sustainable Growth ETF
	Shares	Value
Oil, Gas and Consumable Fuels — 0.6%
ConocoPhillips	357	$	39,074
Personal Products — 0.2%
Estee Lauder Cos., Inc., Class A	40	10,175
Pharmaceuticals — 3.1%
Eli Lilly & Co.	120	36,148
Novo Nordisk A/S, ADR	1,100	116,710
Zoetis, Inc.	303	47,428
		200,286
Road and Rail — 0.9%
Uber Technologies, Inc.(1)	1,161	33,391
Union Pacific Corp.	118	26,492
		59,883
Semiconductors and Semiconductor Equipment — 7.6%
Advanced Micro Devices, Inc.(1)	893	75,789
Analog Devices, Inc.	125	18,941
Applied Materials, Inc.	499	46,941
ASML Holding NV, NY Shares	208	101,907
Lam Research Corp.	114	49,922
NVIDIA Corp.	1,335	201,505
		495,005
Software — 19.7%
Adobe, Inc.(1)	164	61,244
Cadence Design Systems, Inc.(1)	374	64,990
Crowdstrike Holdings, Inc., Class A(1)	167	30,496
Datadog, Inc., Class A(1)	178	18,681
Fair Isaac Corp.(1)	14	6,292
HubSpot, Inc.(1)	36	12,133
Intuit, Inc.	43	18,567
Microsoft Corp.	3,367	880,369
PagerDuty, Inc.(1)	633	16,483
Salesforce, Inc.(1)	299	46,680
ServiceNow, Inc.(1)	182	79,101
Splunk, Inc.(1)	255	22,958
Workday, Inc., Class A(1)	194	31,925
		1,289,919
Specialty Retail — 3.4%
Home Depot, Inc.	384	110,753
TJX Cos., Inc.	1,080	67,338
Ulta Beauty, Inc.(1)	85	35,689
Williams-Sonoma, Inc.	61	9,074
		222,854
Technology Hardware, Storage and Peripherals — 10.5%
Apple, Inc.	4,367	686,580
Textiles, Apparel and Luxury Goods — 1.3%
Deckers Outdoor Corp.(1)	102	32,800
NIKE, Inc., Class B	515	54,822
		87,622
TOTAL COMMON STOCKS (Cost $7,287,618)		6,529,055


Sustainable Growth ETF
	Shares	Value
SHORT-TERM INVESTMENTS — 0.3%
Money Market Funds — 0.3%
State Street Institutional U.S. Government Money Market Fund, Premier Class (Cost $20,203)	20,203	$	20,203
TOTAL INVESTMENT SECURITIES — 99.9% (Cost $7,307,821)		6,549,258
OTHER ASSETS AND LIABILITIES — 0.1%		3,555
TOTAL NET ASSETS — 100.0%		$	6,552,813


AUGUST 31, 2022
	Mid Cap Growth Impact ETF		Sustainable Equity ETF
Assets
Investment securities, at value (cost of $26,161,472 and $104,702,320, respectively) — including $120,684 and $—, respectively of securities on loan	$	23,782,154	$	104,692,893
Investment made with cash collateral received for securities on loan, at value (cost of $123,740 and $—, respectively)	123,740		—
Total investment securities, at value (cost of $26,285,212 and $104,702,320, respectively)	23,905,894		104,692,893
Dividends and interest receivable	6,956		143,756
Securities lending receivable	60		—
	23,912,910		104,836,649

Liabilities
Payable for collateral received for securities on loan	123,740		—
Accrued management fees	9,842		36,515
	133,582		36,515

Net Assets	$	23,779,328	$	104,800,134

Shares outstanding (unlimited number of shares authorized)	540,000		2,150,000

Net Asset Value Per Share	$	44.04	$	48.74

Net Assets Consist of:
Capital paid in	$	29,041,230	$	109,252,139
Distributable earnings	(5,261,902)		(4,452,005)
	$	23,779,328	$	104,800,134


AUGUST 31, 2022
	Sustainable Growth ETF
Assets
Investment securities, at value (cost of $7,307,821)	$	6,549,258
Dividends and interest receivable	5,878
	6,555,136

Liabilities
Accrued management fees	2,323

Net Assets	$	6,552,813

Shares outstanding (unlimited number of shares authorized)	190,000

Net Asset Value Per Share	$	34.49

Net Assets Consist of:
Capital paid in	$	7,703,059
Distributable earnings	(1,150,246)
	$	6,552,813


YEAR ENDED AUGUST 31, 2022
	Mid Cap Growth Impact ETF		Sustainable Equity ETF
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $— and $3,599, respectively)	$	67,118	$	1,829,307
Interest	2,754		1,683
Securities lending, net	143		—
	70,015		1,830,990

Expenses:
Management fees	108,165		542,552

Net investment income (loss)	(38,150)		1,288,438

Realized and Unrealized Gain (Loss)
Net realized gain (loss) on investment transactions	(1,116,341)		12,237,994
Change in net unrealized appreciation (depreciation) on investments	(6,850,129)		(34,780,883)

Net realized and unrealized gain (loss)	(7,966,470)		(22,542,889)

Net Increase (Decrease) in Net Assets Resulting from Operations	$	(8,004,620)	$	(21,254,451)


YEAR ENDED AUGUST 31, 2022
	Sustainable Growth ETF
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $623)	$	44,202
Interest	92
	44,294

Expenses:
Management fees	25,380

Net investment income (loss)	18,914

Realized and Unrealized Gain (Loss)
Net realized gain (loss) on investment transactions	(409,268)
Change in net unrealized appreciation (depreciation) on investments	(1,158,774)

Net realized and unrealized gain (loss)	(1,568,042)

Net Increase (Decrease) in Net Assets Resulting from Operations	$	(1,549,128)


YEARS ENDED AUGUST 31, 2022 AND AUGUST 31, 2021
	Mid Cap Growth Impact ETF				Sustainable Equity ETF
Increase (Decrease) in Net Assets	August 31, 2022		August 31, 2021		August 31, 2022		August 31, 2021
Operations
Net investment income (loss)	$	(38,150)	$	(23,635)	$	1,288,438	$	1,130,539
Net realized gain (loss)	(1,116,341)		184,057		12,237,994		5,728,347
Change in net unrealized appreciation (depreciation)	(6,850,129)		3,888,428		(34,780,883)		28,182,166
Net increase (decrease) in net assets resulting from operations	(8,004,620)		4,048,850		(21,254,451)		35,041,052

Distributions to Shareholders
From earnings	—		—		(1,219,340)		(1,026,655)

Capital Share Transactions
Proceeds from shares sold	17,585,267		13,522,367		52,262,088		56,555,628
Payments for shares redeemed	(7,918,146)		(1,865,381)		(75,423,895)		(24,927,794)
Net increase (decrease) in net assets from capital share transactions	9,667,121		11,656,986		(23,161,807)		31,627,834

Net increase (decrease) in net assets	1,662,501		15,705,836		(45,635,598)		65,642,231

Net Assets
Beginning of period	22,116,827		6,410,991		150,435,732		84,793,501
End of period	$	23,779,328	$	22,116,827	$	104,800,134	$	150,435,732

Transactions in Shares of the Funds
Sold	340,000		250,000		940,000		1,170,000
Redeemed	(165,000)		(35,000)		(1,420,000)		(460,000)
Net increase (decrease) in shares of the funds	175,000		215,000		(480,000)		710,000


YEAR ENDED AUGUST 31, 2022 AND PERIOD ENDED AUGUST 31, 2021
	Sustainable Growth ETF
Increase (Decrease) in Net Assets	August 31, 2022		August 31, 2021(1)
Operations
Net investment income (loss)	$	18,914	$	1,272
Net realized gain (loss)	(409,268)		(9,099)
Change in net unrealized appreciation (depreciation)	(1,158,774)		400,211
Net increase (decrease) in net assets resulting from operations	(1,549,128)		392,384

Distributions to Shareholders
From earnings	(13,482)		—

Capital Share Transactions
Proceeds from shares sold	2,444,496		5,651,186
Payments for shares redeemed	(372,643)		—
Net increase (decrease) in net assets from capital share transactions	2,071,853		5,651,186

Net increase (decrease) in net assets	509,243		6,043,570

Net Assets
Beginning of period	6,043,570		—
End of period	$	6,552,813	$	6,043,570

Transactions in Shares of the Funds
Sold	60,000		140,000
Redeemed	(10,000)		—
Net increase (decrease) in shares of the funds	50,000		140,000

American Century ETF Trust (the trust) was registered as a Delaware statutory trust in 2017 and is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company. American Century Mid Cap Growth Impact ETF (Mid Cap Growth Impact ETF), American Century Sustainable Equity ETF (Sustainable Equity ETF) and American Century Sustainable Growth ETF (Sustainable Growth ETF) (collectively, the funds) are three funds in a series issued by the trust. The investment objective for Mid Cap Growth Impact ETF and Sustainable Equity ETF is to seek long-term capital growth. Sustainable Growth ETF's investment objective is to seek capital appreciation. Shares of each fund are listed for trading on the NYSE Arca, Inc. Sustainable Growth ETF incepted on June 29, 2021.

The following is a summary of significant accounting policies consistently followed by the funds in preparation of their financial statements. Each fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The funds determine the fair value of their investments and compute their net asset value (NAV) per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Trustees has adopted valuation policies and procedures to guide the investment advisor in the funds' investment valuation process and to provide methodologies for the oversight of the funds' pricing function.

Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price.

If the funds determine that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Trustees or its delegate, in accordance with policies and procedures adopted by the Board of Trustees. In its determination of fair value, the funds may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the funds to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.

The funds monitor for significant events occurring after the close of an investment’s primary exchange but before each fund’s NAV per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The funds also monitor for significant fluctuations between domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Trustees, or its delegate, deems appropriate. The funds may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.

Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The funds may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes accretion of discounts and amortization of premiums. Securities lending income is net of fees and rebates earned by the lending agent for its services.

Segregated Assets — In accordance with the 1940 Act, the funds segregate assets on their books and records to cover certain types of investment securities and other financial instruments. American Century Investment Management, Inc. (ACIM) (the investment advisor) monitors, on a daily basis, the securities segregated to ensure the funds designate a sufficient amount of liquid assets, marked-to-market daily. The funds may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.

Income Tax Status — It is each fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The funds file U.S. federal, state, local and non-U.S. tax returns as applicable. The funds' tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.

Distributions to Shareholders — Distributions from net investment income, if any, are generally declared and paid quarterly. Distributions from net realized gains, if any, are generally declared and paid annually. Each fund may elect to treat a portion of its payment to a redeeming shareholder, which represents the pro rata share of undistributed net investment income and net realized gains, as a distribution for federal income tax purposes (tax equalization).

Indemnifications — Under the trust’s organizational documents, its officers and trustees are indemnified against certain liabilities arising out of the performance of their duties to the funds. In addition, in the normal course of business, the funds enter into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.

Securities Lending — Securities are lent to qualified financial institutions and brokers. State Street Bank & Trust Co. serves as securities lending agent to the funds pursuant to a Securities Lending Agreement. The lending of securities exposes the funds to risks such as: the borrowers may fail to return the loaned securities, the borrowers may not be able to provide additional collateral, the funds may experience delays in recovery of the loaned securities or delays in access to collateral, or the funds may experience losses related to the investment collateral. To minimize certain risks, loan counterparties pledge collateral in the form of cash and/or securities. The lending agent has agreed to indemnify the funds in the case of default of any securities borrowed. Cash collateral received is invested in the State Street Navigator Securities Lending Government Money Market Portfolio, a money market mutual fund registered under the 1940 Act. The loans may also be secured by U.S. government securities in an amount at least equal to the market value of the securities loaned, plus accrued interest and dividends, determined on a daily basis and adjusted accordingly. By lending securities, the funds seek to increase their net investment income through the receipt of interest and fees. Such income is reflected separately within the Statements of Operations. The value of loaned securities and related collateral outstanding at period end, if any, are shown on a gross basis within the Schedules of

Certain officers and trustees of the trust are also officers and/or directors of American Century Companies, Inc. (ACC). The trust's investment advisor, ACIM, and the trust’s administrator, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC. ACIM owns 10% and 66% of the shares of Mid Cap Growth Impact ETF and Sustainable Growth ETF, respectively. Related parties do not invest in the funds for the purpose of exercising management or control.

Management Fees — The trust has entered into a management agreement with ACIM, under which ACIM provides the funds with investment advisory and management services in exchange for a single, unified management fee (the fee). The agreement provides that ACIM will pay all expenses of managing and operating the funds, except brokerage and other transaction fees and expenses relating to the acquisition and disposition of portfolio securities, acquired fund fees and expenses, interest, taxes, litigation expenses and extraordinary expenses. The fee is computed and accrued daily based on the daily net assets of each fund and paid monthly in arrears.

Interfund Transactions — The funds may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Trustees. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. There were no interfund transactions during the period.

Each fund’s shares may only be bought and sold in a secondary market through a broker-dealer at a market price. Because ETF shares trade at market prices rather than NAV, shares may trade at a price greater than NAV (a premium) or less than NAV (a discount). Each fund issues and redeems shares at their NAV only in aggregations of a specified number of shares (a creation unit) generally in exchange for a designated portfolio of securities and/or cash (including any portion of such securities for which cash may be substituted). Authorized participants may be required to pay an additional variable charge to cover certain brokerage, tax, foreign exchange, execution, market impact and other costs and expenses related to the execution of trades resulting from creation unit transactions. Such variable charges, if any, are included in other capital within the Statements of Changes in Net Assets.

The funds’ investment valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the funds. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

•Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

The value of the funds’ shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the funds and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the funds’ investments. Natural disasters, public health emergencies, war, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.

The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.


	Mid Cap Growth Impact ETF		Sustainable Equity ETF		Sustainable Growth ETF
Federal tax cost of investments	$	26,371,870	$	105,078,846	$	7,332,280
Gross tax appreciation of investments	$	1,846,203	$	6,016,523	$	211,882
Gross tax depreciation of investments	(4,312,179)		(6,402,476)		(994,904)
Net tax appreciation (depreciation) of investments	$	(2,465,976)	$	(385,953)	$	(783,022)
Undistributed ordinary income	—		$	142,411	$	6,680
Accumulated short-term capital losses	$	(2,413,713)	$	(3,055,556)	$	(358,971)
Accumulated long-term capital losses	$	(339,568)	$	(1,152,907)	$	(14,933)
Late-year ordinary loss deferral	$	(42,645)	—		—

Accumulated capital losses represent net capital loss carryovers that may be used to offset future realized capital gains for federal income tax purposes. The capital loss carryovers may be carried forward for an unlimited period. Future capital loss carryover utilization in any given year may be subject to Internal Revenue Code limitations.


For a Share Outstanding Throughout the Years Ended August 31 (except as noted)
Per-Share Data							Ratios and Supplemental Data
		Income From Investment Operations:					Ratio to Average Net Assets of:
	Net Asset Value, Beginning of Period	Net Investment Income (Loss)(1)	Net Realized and Unrealized Gain (Loss)	Total From Investment Operations	Net Asset Value, End of Period	Total Return(2)	Operating Expenses	Net Investment Income (Loss)	Portfolio Turnover Rate(3)	Net Assets, End of Period (in thousands)
Mid Cap Growth Impact ETF
2022	$60.59	(0.08)	(16.47)	(16.55)	$44.04	(27.33)%	0.45%	(0.16)%	44%	$23,779
2021	$42.74	(0.11)	17.96	17.85	$60.59	41.78%	0.45%	(0.20)%	48%	$22,117
2020(4)	$38.45	(0.02)	4.31	4.29	$42.74	11.14%	0.45%(5)	(0.29)%(5)	2%	$6,411


For a Share Outstanding Throughout the Years Ended August 31 (except as noted)
Per-Share Data								Ratios and Supplemental Data
		Income From Investment Operations:						Ratio to Average Net Assets of:
	Net Asset Value, Beginning of Period	Net Investment Income (Loss)(1)	Net Realized and Unrealized Gain (Loss)	Total From Investment Operations	Distributions From Net Investment Income	Net Asset Value, End of Period	Total Return(2)	Operating Expenses	Net Investment Income (Loss)	Portfolio Turnover Rate(3)	Net Assets, End of Period (in thousands)
Sustainable Equity ETF
2022	$57.20	0.50	(8.49)	(7.99)	(0.47)	$48.74	(14.03)%	0.39%	0.93%	21%	$104,800
2021	$44.16	0.45	13.01	13.46	(0.42)	$57.20	30.65%	0.39%	0.91%	22%	$150,436
2020(4)	$39.59	0.06	4.51	4.57	—	$44.16	11.56%	0.39%(5)	1.13%(5)	10%	$84,794

For a Share Outstanding Throughout the Years Ended August 31 (except as noted)

Per-Share Data

Ratios and Supplemental Data

Income From Investment Operations:

Ratio to Average Net Assets of:

Net
Asset Value, Beginning
of Period

Net

Investment

Income (Loss)(1)

Net
Realized and
Unrealized
Gain (Loss)

Total From
Investment
Operations

Distributions From Net Investment Income

Net Asset Value, End of Period



			Annual Report

			August 31, 2022

			American Century® Mid Cap Growth Impact ETF (MID)
			American Century® Sustainable Equity ETF (ESGA)
			American Century® Sustainable Growth ETF (ESGY)


	Mid Cap Growth Impact ETF	Sustainable Equity ETF	Sustainable Growth ETF
Purchases	$10,460,470	$30,642,094	$1,948,097
Sales	$10,285,647	$28,855,996	$1,904,369


	In kind Subscriptions	In kind Redemptions	In kind Net Realized Gain/(Loss)*
Mid Cap Growth Impact ETF	$16,899,888	$7,602,890	$1,592,068
Sustainable Equity ETF	$46,888,848	$71,768,008	$16,603,849
Sustainable Growth ETF	$2,384,602	$362,134	$7,010


	Mid Cap Growth Impact ETF		Sustainable Equity ETF		Sustainable Growth ETF
Capital paid in	$	1,483,139	$	16,594,854	(19,980)
Distributable earnings	$	(1,483,139)	$	(16,594,854)	19,980


Growth of $10,000 Over Life of Fund
$10,000 investment made July 13, 2020


Value on August 31, 2022
			Net Asset Value — $11,451

			Russell Midcap Growth Index — $10,931


Value on August 31, 2022
			Net Asset Value — $12,531

			S&P 500 Index — $12,948


Growth of $10,000 Over Life of Fund
$10,000 investment made June 29, 2021


Value on August 31, 2022
			Net Asset Value — $8,609

			Russell 1000 Growth Index — $8,655


NOTES TO SCHEDULE OF INVESTMENTS
ADR	-	American Depositary Receipt


Remaining Contractual Maturity of Agreements
Fund/Securities Lending Transactions(1)	Overnight and Continuous		<30 days	Between 30 & 90 days	>90 days	Total
Mid Cap Growth Impact ETF
Common Stocks	$	123,740	—	—	—	$	123,740
Gross amount of recognized liabilities for securities lending transactions						$	123,740


			Annual Management Fee
Mid Cap Growth Impact ETF			0.45%
Sustainable Equity ETF			0.39%
Sustainable Growth ETF			0.39%


	2022			2021
	Distributions Paid From:			Distributions Paid From:
	Ordinary Income		Long-term Capital Gains	Ordinary Income		Long-term Capital Gains
Mid Cap Growth Impact ETF	—		—	—		—
Sustainable Equity ETF	$	1,219,340	—	$	1,026,655	—
Sustainable Growth ETF(1)	$	13,482	—	—		—


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