FORM 6-K 

SECURITIES AND EXCHANGE COMMISSION 

Washington, D.C. 20549

Report of Foreign Issuer

Pursuant to Rule 13a-16 or 15d-16 of 

the Securities Exchange Act of 1934

For the month of July, 2019

Commission File Number: 001-12518

Banco Santander, S.A.

(Exact name of registrant as specified in its charter)

Ciudad Grupo Santander

28660 Boadilla del Monte (Madrid) Spain

(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):

Banco Santander, S.A.

TABLE OF CONTENTS

Item 1

Banco Santander, S.A., pursuant to the provisions of the Spanish Securities Market Act (Ley del Mercado de Valores), hereby announces the following:

RELEVANT INFORMATION

Attached is a presentation containing selected quarterly consolidated financial information by segments for 2018 and the first quarter of 2019 which has been prepared following the new organisational structure of the Group as detailed below. The consolidated financial information for the second quarter of 2019 will be provided on this new basis and, therefore, the 2018 and first quarter of 2019 data are provided to allow better quarter-on-quarter and year-on-year comparability. The modification of this information provided by segments does not result in any alteration into the consolidated financial information of the Group, including its results and equity.

This new reporting is the result of the changes to the organisational structure announced at the Investor Day held on 3 April which led to the creation of three regions (Europe, North America and South America) as well as the following modifications to the perimeter of some countries: Santander UK whose perimeter has been aligned to the segregated model according to the requirements of the Banking Reform Act (Ring-fenced and Non Ring-fenced business), and Spain to the local customer related business (with the Boadilla Hub now included within the rest of Europe, the Real Estate Activity Spain unit included within Spain, and Openbank moved from Spain to a new Santander Global Platform area).

The Santander Global Platform (SGP) area has been created to consolidate all the global digital services (Openbank, Open Digital Services, Global Payments Services, and Digital Assets) under a single umbrella.

Regarding the secondary segments, the insurance business, previously included in Retail Banking, is now included in Wealth Management, which has been renamed Wealth Management & Insurance. Furthermore, changes related to the Global Customer Relationship Model have been made, with a recurring annual adjustment to the perimeter between Retail Banking, Santander Wealth Management & Insurance and Santander Corporate & Investment Banking. These changes do not impact the geographic businesses.

Boadilla del Monte (Madrid), 4 July 2019

Item 2

2018 and Q1’19 income statements and balance sheets according to the new reporting structure July 2019

2 Important information Non - IFRS and alternative performance measures In addition to the financial information prepared in accordance with International Financial Reporting Standards (“IFRS”), this presentation contains certain financial measures that constitute alternative performance measures (“APMs”) as defined in the Guidelines on Alternative Performance Measures issued by the European Securities and Markets Authority (ESMA) on 5 October 2015 (ESMA/ 2015 / 1415 en) and other non - IFRS measures (“Non - IFRS Measures”) . The financial measures contained in this presentation that qualify as APMs and non - IFRS measures have been calculated using the financial information from Santander Group but are not defined or detailed in the applicable financial reporting framework and have neither been audited nor reviewed by our auditors . We use these APMs and non - IFRS measures when planning, monitoring and evaluating our performance . We consider these APMs and non - IFRS measures to be useful metrics for management and investors to facilitate operating performance comparisons from period to period . While we believe that these APMs and non - IFRS measures are useful in evaluating our business, this information should be considered as supplemental in nature and is not meant as a substitute of IFRS measures . In addition, other companies, including companies in our industry, may calculate or use such measures differently, which reduces their usefulness as comparative measures . For further details of the APMs and non - IFRS Measures used, including their definition or a reconciliation between any applicable management indicators and the financial data presented in the consolidated financial statements prepared under IFRS, please see 2019 1 Q Financial Report, published as Relevant Fact on 30 April 2019 and 2018 Annual Financial Report, published as Relevant Fact on 28 February 2019 . These documents are available on Santander’s website ( www . santander . com ) . The businesses included in each of our geographic segments and the accounting principles under which their results are presented here may differ from the included businesses and local applicable accounting principles of our public subsidiaries in such geographies . Accordingly, the results of operations and trends shown for our geographic segments may differ materially from those of such subsidiaries . Forward - looking statements Santander cautions that this presentation contains statements that constitute “forward - looking statements” within the meaning of the U . S . Private Securities Litigation Reform Act of 1995 . Forward - looking statements may be identified by words such as “expect”, “project”, “anticipate”, “should”, “intend”, “probability”, “risk”, “ target”, “goal”, “objective”, “estimate”, “future” and similar expressions . These forward - looking statements are found in various places throughout this presentation and include, without limitation, statements concerning our future business development and economic performance and our shareholder remuneration policy . While these forward - looking statements represent our judgment and future expectations concerning the development of our business, a number of risks, uncertainties and other important factors could cause actual developments and results to differ materially from our expectations . The following important factors, in addition to those discussed elsewhere in this presentation, could affect our future results and could cause outcomes to differ materially from those anticipated in any forward - looking statement : ( 1 ) general economic or industry conditions in areas in which we have significant business activities or investments, including a worsening of the economic environment, increasing in the volatility of the capital markets, inflation or deflation, and changes in demographics, consumer spending, investment or saving habits ; ( 2 ) exposure to various types of market risks, principally including interest rate risk, foreign exchange rate risk, equity price risk and risks associated with the replacement of benchmark indices ; ( 3 ) potential losses associated with prepayment of our loan and investment portfolio, declines in the value of collateral securing our loan portfolio, and counterparty risk ; ( 4 ) political stability in Spain, the UK, other European countries, Latin America and the US ( 5 ) changes in laws, regulations or taxes, including changes in regulatory capital or liquidity requirements, including as a result of the UK exiting the European Union and increased regulation in light of the global financial crisis ; ( 6 ) our ability to integrate successfully our acquisitions and the challenges inherent in diverting management’s focus and resources from other strategic opportunities and from operational matters while we integrate these acquisitions ; and ( 7 ) changes in our ability to access liquidity and funding on acceptable terms, including as a result of changes in our credit spreads or a downgrade in our credit ratings or those of our more significant subsidiaries . Numerous factors could affect the future results of Santander and could result in those results deviating materially from those anticipated in the forward - looking statements . Other unknown or unpredictable factors could cause actual results to differ materially from those in the forward - looking statements .

3 Forward - looking statements speak only as of the date of this presentation and are based on the knowledge, information available and views taken on such date ; such knowledge, information and views may change at any time . Santander does not undertake any obligation to update or revise any forward - looking statement, whether as a result of new information, future events or otherwise . No offer The information contained in this presentation is subject to, and must be read in conjunction with, all other publicly available information, including, where relevant any fuller disclosure document published by Santander . Any person at any time acquiring securities must do so only on the basis of such person’s own judgment as to the merits or the suitability of the securities for its purpose and only on such information as is contained in such public information having taken all such professional or other advice as it considers necessary or appropriate in the circumstances and not in reliance on the information contained in this presentation . No investment activity should be undertaken on the basis of the information contained in this presentation . In making this presentation available Santander gives no advice and makes no recommendation to buy, sell or otherwise deal in shares in Santander or in any other securities or investments whatsoever . Neither this presentation nor any of the information contained therein constitutes an offer to sell or the solicitation of an offer to buy any securities . No offering of securities shall be made in the United States except pursuant to registration under the U . S . Securities Act of 1933 , as amended, or an exemption therefrom . Nothing contained in this presentation is intended to constitute an invitation or inducement to engage in investment activity for the purposes of the prohibition on financial promotion in the U . K . Financial Services and Markets Act 2000 . Historical performance is not indicative of future results Statements as to historical performance or financial accretion are not intended to mean that future performance, share price or future earnings (including earnings per share) for any period will necessarily match or exceed those of any prior period . Nothing in this presentation should be construed as a profit forecast . Important Information

4 Adapting our reporting to the new organisational structure and according to IFRS 8 requirements  3 regions : Europe, North America and South America  Converging the business model, the IT&Ops and shared services  UK aligned with ring - fencing structure and Spain with the local customer related business Main changes in the organisational structure 1  To accelerate progress towards the best open financial services platform  Our digital services are consolidated under a single unit - Openbank and Open Digital Services (ODS) - Global Payments Services - Digital Assets Creation of Santander Global Platform (SGP) 2

5 Global Divisions expenses Cost allocation to countries / Transfer SAN Digital Division expenses REST OF EUROPE “From 30 June on…” “Until now…” SAN Spain Openbank Hub Madrid 1 SAN Spain Platforms (ODS) 2 SAN UK Hub UK 1 (including London Branch) SAN UK Ring Fence CIB Rest of Europe WM Rest of Europe Real E state Spain Primary segments - Main changes in the organisational structure and creation of SGP These changes do not entail any alteration in the Group figures Santander Global Platform (Global Payments Services, Openbank, ODS 2 and Digital Assets 3 ) Hub UK 1 (including London Branch) Hub Madrid 1 SANTANDER GLOBAL PLATFORM (SGP) Real Estate Spain (1) CIB operating Hub: UK and Madrid (excluding structural liquidity, which is allocated in the Corporate Centre). (2) ODS ( Open Digital Services): technology company developing a new banking platform to be used by Openbank in its international expansion, and it can be used to serve third parties. (3) Centres of Expertise: Centres with global capabilities to drive digital transformation with tangible impact on the local businesses. Regarding the secondary segments, the insurance business , previously included in Retail Banking, is now included in the Wealth Management segment, which is renamed Wealth Management & Insurance. Furthermore Global Customer Relationship Model : recurring annual adjustment to the perimeter between Retail Banking, Santander Wealth Management and Insurance (WM&I) and Santander Corporate & Investment Banking (SCIB). These changes had no impact on the geographic businesse s. CORPORATE CENTRE Group’s holding entity and centralised activities CIB Rest of Europe WM Rest of Europe Digital Assets 3 (Centres of Expertise) Group’s holding entity and centralised activities

6 3 new regions: Europe, North America and South America Europe South America North America Mexico United States Brazil Chile Argentina Uruguay Peru Colombia SCF Spain SCF United Kingdom Portugal Poland Rest of Europe Regional structure 1

7 South America North America Europe Commercial Medium - term 2018 goals Loyal / Active customers Digital customers # of countries top3 in CSAT C/I RoTE 2 RoRWA 2 Financial New geographical areas. Key metrics 2018 and medium - term goals Key metrics Medium - term 2018 goals Medium - term 2018 goals 1 33% 40 % 13Mn c.16Mn All Maintain 53% 47 - 49% 11% 12 - 14% 1.5% c.2% 27% 31 % 4Mn c.7Mn 1 * Maintain 43 % 39 - 41 % 12% 1 14 - 16% 1 1.7% c.2% 27% 31% 15Mn c.20Mn 3 All 37% 33 - 35 % 19% 20 - 22 % 3.2% c.3.5% Targets published in the Investor Day adapted to the new geographic areas only. Group targets are unchanged. (*) US (SBNA): 9 th in 2018; medium - term target: peer average (1) Adjusted US for excess of capital (2) Underlying

8 RoTE (%) 20 % >20% 10 % 14 - 16% 16 % 14 - 15 % 9% 9 - 11% 20 % 19 - 21% 8% 1 11 - 13% 1 18 % 19 - 20% 12 % 13 - 15% 13% 2 14 - 16% 2 Medium - term goals RoTE 2018 and medium - term goals by countries 2018 (1) Adjusted for excess of capital (2) Adjusted for excess of capital. Otherwise, RoTE in 2018 at 10% and medium - term goal 12 - 14%

9 Creation of Santander Global Platform (SGP) 2 Santander Global Platform (SGP) Digital Assets • Digital assets – SaaS model 1 • Centres of Expertise 2 • InnoVentures C Openbank • Openbank • Open Digital Services (ODS) A Fully digital banking platform and value proposition in our existing markets and in new markets Our common digital assets and Centres of Digital Expertise help our banks in their digital transformation Global Payments Services Payments platform to better serve existing and new customers with best - in - class value propositions developed globally • Superdigital • Pago FX • Global Merchant Services (GMS) • Global Trade Services (GTS) B Payments platform to better serve existing and new customers with best - in - class value propositions developed globally (1) SaaS : Software as a Service (2) Contact Centre Digitalisation; Conversion Rate Optimisation; Machine Learning; …

10 ■ Primary segments

11 Main differences in underlying p rofit of p rimary segments. Income statement of the Group does not change New criteria Previous criteria Difference UK Spain Rest of Europe SGP Corporate Centre Other countries 0 TOTAL GROUP 0 - 90 - 184 +324 - 54 +35 - 31 1,362 1,738 - 170 - - 1,721 1,272 1,554 154 - 54 - 1,686 SGP New criteria Previous criteria Difference - 17 - 47 +86 - 11 - 3 - 8 271 403 - 54 - - 514 254 356 32 - 11 - 517 0 2018 Q1’19 (1) SAN Hub UK (including London Branch) out of UK (in Rest of Europe) (2) Real Estate Spain unit included in SPAIN and exit of Openbank (to SGP) and Hub Madrid (to Rest of Europe) (3) Mainly from the inclusion of Hub UK (including London Branch) and Hub Madrid and the exclusion of Real Estate Spain unit and ODS (4) Cost from Centres of Expertise allocated to countries 1 2 3 4 EUR m illion

12 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. EUROPE (Europe vs Continental Europe + UK) EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 3,502 3,508 3,562 3,631 3,561 3,511 3,518 3,572 3,642 3,571 (9) (10) (10) (10) (10) Net fee income 1,372 1,382 1,354 1,327 1,327 1,373 1,383 1,355 1,331 1,326 (1) (1) (1) (4) 1 Gains (losses) on financial transactions * 322 160 341 292 186 322 160 341 291 184 (0) (0) (0) 0 1 Other operating income 155 123 162 64 152 152 120 160 70 147 3 2 2 (6) 4 Total income 5,352 5,173 5,419 5,314 5,225 5,358 5,182 5,429 5,333 5,229 (7) (9) (10) (19) (3) Administrative expenses and amortisations (2,841) (2,825) (2,735) (2,764) (2,802) (2,857) (2,857) (2,759) (2,799) (2,831) 16 32 24 36 29 Net operating income 2,510 2,348 2,684 2,550 2,423 2,501 2,325 2,669 2,534 2,397 9 23 14 16 26 Net loan-loss provisions (457) (403) (406) (306) (457) (456) (403) (407) (307) (456) (0) 0 0 0 (1) Other gains (losses) and provisions (195) (194) (205) (435) (198) (195) (194) (205) (435) (216) 1 0 1 0 19 Profit before tax 1,859 1,751 2,072 1,809 1,768 1,849 1,728 2,057 1,792 1,725 10 23 15 17 44 Tax on profit (500) (475) (575) (470) (492) (499) (467) (570) (464) (479) (1) (8) (5) (6) (13) Profit from continuing operations 1,359 1,276 1,498 1,339 1,276 1,350 1,261 1,488 1,328 1,245 9 15 10 11 31 Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 1,359 1,276 1,498 1,339 1,276 1,350 1,261 1,488 1,328 1,245 9 15 10 11 31 Non-controlling interests (99) (114) (114) (97) (113) (99) (113) (114) (96) (103) (0) (1) (0) (0) (10) Underlying attributable profit to the parent 1,260 1,162 1,384 1,242 1,163 1,251 1,148 1,374 1,232 1,142 9 14 10 11 21 NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 631,798 634,893 631,215 639,966 655,947 631,928 635,086 633,231 640,304 656,389 (130) (193) (2,016) (338) (441) Cash, central banks and credit institutions 171,923 177,456 176,126 172,298 181,638 168,317 183,083 178,768 182,656 185,613 3,606 (5,627) (2,642) (10,358) (3,975) Debt instruments 120,896 116,957 117,263 118,221 115,966 120,896 116,957 117,263 118,221 116,283 — — — — (318) Other financial assets 58,931 58,070 54,857 49,263 54,448 59,033 58,209 54,990 49,410 54,600 (102) (139) (133) (146) (152) Other asset accounts 47,670 46,748 45,850 40,989 44,790 47,278 46,372 45,495 40,650 44,948 391 375 355 339 (157) Total assets 1,031,217 1,034,124 1,025,312 1,020,737 1,052,789 1,027,451 1,039,708 1,029,748 1,031,240 1,057,832 3,765 (5,584) (4,436) (10,503) (5,043) Customer deposits 565,239 570,881 569,779 571,834 587,365 572,427 578,359 577,546 580,118 596,168 (7,188) (7,477) (7,767) (8,284) (8,804) Central banks and credit institutions 205,454 204,518 199,387 192,685 201,953 191,900 199,991 193,136 192,190 196,486 13,553 4,527 6,251 495 5,467 Marketable debt securities 122,816 123,570 125,483 129,574 129,147 122,816 123,570 125,483 129,574 129,147 — — — (0) — Other financial liabilities 64,568 61,062 59,189 53,687 60,267 64,596 61,108 59,223 53,725 60,309 (27) (46) (34) (39) (42) Other liabilities accounts 21,381 20,578 19,165 18,947 18,430 21,433 20,710 19,297 19,008 18,493 (51) (133) (133) (61) (62) Total liabilities 979,458 980,609 973,002 966,727 997,163 973,172 983,738 974,685 974,616 1,000,603 6,286 (3,129) (1,683) (7,889) (3,441) Total equity 51,758 53,515 52,309 54,010 55,627 54,279 55,970 55,062 56,624 57,229 (2,521) (2,455) (2,753) (2,614) (1,602) Pro memoria: Gross loans and advances to customers ** 621,950 626,025 621,994 626,205 639,447 622,082 626,221 622,249 626,546 639,891 (133) (196) (255) (341) (445) Customer funds 624,165 628,709 631,200 634,893 652,389 631,960 636,791 639,370 643,543 661,571 (7,795) (8,082) (8,170) (8,650) (9,183) Customer deposits *** 541,435 545,985 547,586 557,122 569,699 548,623 553,463 555,353 565,406 578,503 (7,188) (7,477) (7,767) (8,284) (8,804) Mutual funds 82,730 82,724 83,613 77,771 82,689 83,337 83,329 84,016 78,138 83,068 (607) (605) (403) (367) (379)

13 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. Spain EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 969 1,026 1,044 1,054 1,009 1,037 1,058 1,116 1,150 1,098 (67) (32) (72) (96) (89) Net fee income 669 671 651 633 623 673 671 653 634 614 (4) (0) (2) (0) 9 Gains (losses) on financial transactions * 120 151 259 173 119 206 31 227 95 70 (86) 120 31 78 49 Other operating income 127 12 111 (56) 105 148 77 118 1 155 (20) (65) (7) (57) (50) Total income 1,885 1,860 2,065 1,804 1,857 2,063 1,837 2,114 1,880 1,938 (178) 23 (49) (75) (81) Administrative expenses and amortisations (1,112) (1,093) (1,065) (1,068) (1,025) (1,145) (1,123) (1,103) (1,110) (1,079) 33 30 37 42 55 Net operating income 773 767 1,000 737 832 918 714 1,012 770 858 (145) 53 (12) (33) (27) Net loan-loss provisions (217) (220) (213) (140) (242) (207) (196) (197) (129) (218) (10) (24) (16) (11) (25) Other gains (losses) and provisions (131) (102) (132) (60) (112) (104) (86) (102) (70) (97) (27) (15) (30) 10 (15) Profit before tax 425 446 655 537 478 608 432 713 571 544 (183) 13 (58) (34) (66) Tax on profit (99) (111) (169) (129) (122) (153) (107) (186) (139) (141) 54 (4) 17 10 20 Profit from continuing operations 326 335 486 408 356 455 326 526 432 403 (128) 9 (41) (24) (47) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 326 335 486 408 356 455 326 526 432 403 (128) 9 (41) (24) (47) Non-controlling interests (0) (0) (0) (0) 0 (0) (0) (0) (0) 0 (0) 0 0 0 — Underlying attributable profit to the parent 326 335 486 408 356 455 325 526 432 403 (128) 9 (41) (24) (47) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 201,232 202,351 197,144 196,101 194,308 219,222 217,754 212,247 206,776 207,417 (17,990) (15,403) (15,104) (10,676) (13,109) Cash, central banks and credit institutions 74,210 76,019 78,961 79,100 80,513 99,825 104,762 113,986 117,215 117,102 (25,615) (28,743) (35,025) (38,114) (36,589) Debt instruments 55,952 51,808 49,947 48,849 41,929 70,970 65,645 63,933 60,720 59,658 (15,018) (13,837) (13,986) (11,872) (17,729) Other financial assets 2,736 3,164 2,724 2,515 1,925 33,794 34,316 31,052 32,727 37,416 (31,057) (31,151) (28,328) (30,211) (35,491) Other asset accounts 27,183 26,351 27,198 22,436 24,712 21,074 20,209 21,251 16,644 20,906 6,109 6,141 5,948 5,792 3,806 Total assets 361,313 359,693 355,974 349,001 343,386 444,884 442,686 442,469 434,082 442,498 (83,571) (82,993) (86,495) (85,081) (99,112) Customer deposits 234,302 238,243 238,607 238,372 242,570 248,858 253,650 253,177 255,402 260,616 (14,555) (15,407) (14,569) (17,030) (18,046) Central banks and credit institutions 69,805 64,964 61,076 56,062 46,692 103,655 97,122 101,307 93,854 98,591 (33,850) (32,158) (40,231) (37,792) (51,899) Marketable debt securities 24,967 24,185 23,527 24,628 23,386 24,998 24,196 23,544 24,608 23,369 (31) (10) (16) 20 16 Other financial liabilities 7,302 7,416 9,236 6,216 8,027 40,846 41,520 39,246 35,054 37,034 (33,544) (34,105) (30,010) (28,838) (29,008) Other liabilities accounts 10,113 9,937 8,940 8,916 7,491 10,205 10,004 9,031 8,878 7,468 (92) (66) (92) 38 24 Total liabilities 346,490 344,745 341,387 334,193 328,166 428,562 426,491 426,305 417,796 427,078 (82,073) (81,746) (84,918) (83,602) (98,912) Total equity 14,823 14,948 14,587 14,807 15,220 16,322 16,195 16,164 16,286 15,420 (1,498) (1,247) (1,577) (1,479) (200) Pro memoria: Gross loans and advances to customers ** 209,912 210,508 206,675 203,288 201,277 216,907 218,191 214,346 209,630 209,608 (6,996) (7,682) (7,671) (6,342) (8,331) Customer funds 298,375 302,618 304,093 298,860 306,797 313,399 318,387 318,859 315,351 324,903 (15,024) (15,769) (14,766) (16,492) (18,106) Customer deposits *** 233,894 237,645 238,103 237,821 241,928 248,315 252,813 252,466 253,946 259,654 (14,421) (15,168) (14,363) (16,125) (17,727) Mutual funds 64,481 64,973 65,990 61,039 64,870 65,084 65,574 66,392 61,406 65,248 (603) (601) (403) (367) (379)

14 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. Santander Consumer Finance EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 915 928 937 943 941 915 928 937 943 941 — — — — — Net fee income 215 188 206 189 214 215 188 206 189 214 — — — — — Gains (losses) on financial transactions * 4 16 1 35 2 4 16 1 35 2 — — 0 — — Other operating income 6 (5) 13 21 11 6 (5) 13 21 11 — 0 — (0) — Total income 1,140 1,126 1,157 1,187 1,167 1,140 1,126 1,157 1,187 1,167 — — — — — Administrative expenses and amortisations (510) (508) (476) (495) (508) (509) (507) (475) (494) (507) (1) (1) (1) (1) (1) Net operating income 630 618 681 692 659 631 619 682 693 660 (1) (1) (1) (1) (1) Net loan-loss provisions (120) (69) (124) (47) (122) (120) (69) (124) (47) (122) — — — — — Other gains (losses) and provisions 24 13 5 (166) 24 24 13 5 (166) 24 — 0 (0) — — Profit before tax 534 562 561 479 561 535 563 562 480 562 (1) (1) (1) (1) (1) Tax on profit (146) (151) (157) (122) (159) (147) (151) (157) (122) (159) 0 0 0 0 0 Profit from continuing operations 388 411 405 357 402 388 412 405 358 403 (1) (1) (1) (1) (1) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 388 411 405 357 402 388 412 405 358 403 (1) (1) (1) (1) (1) Non-controlling interests (66) (66) (74) (62) (78) (66) (66) (74) (62) (78) — — — — — Underlying attributable profit to the parent 322 345 331 295 324 323 346 332 296 325 (1) (1) (1) (1) (1) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 89,718 91,861 92,070 95,366 95,770 89,718 91,861 92,070 95,366 95,770 — — — — — Cash, central banks and credit institutions 5,964 5,197 5,784 6,096 6,299 5,964 5,197 5,784 6,096 6,299 — — — — — Debt instruments 3,302 3,222 3,446 3,325 3,443 3,302 3,222 3,446 3,325 3,443 — — — — — Other financial assets 19 21 20 31 33 19 21 20 31 33 — — — — — Other asset accounts 3,607 3,578 3,087 2,890 3,730 3,607 3,578 3,087 2,890 3,730 — — — — — Total assets 102,609 103,879 104,406 107,708 109,275 102,609 103,879 104,406 107,708 109,275 — — — — — Customer deposits 36,894 36,774 36,683 36,579 36,898 36,894 36,774 36,683 36,579 36,898 — — — — — Central banks and credit institutions 23,314 25,190 25,211 24,968 24,755 23,313 25,189 25,209 24,966 24,755 1 1 2 3 1 Marketable debt securities 28,126 27,336 27,529 31,281 32,070 28,126 27,336 27,529 31,281 32,070 — — — — — Other financial liabilities 1,013 995 874 771 1,194 1,013 995 874 771 1,194 — — — — — Other liabilities accounts 3,805 3,687 3,781 3,520 3,755 3,805 3,687 3,781 3,520 3,755 — — — — — Total liabilities 93,152 93,981 94,077 97,120 98,673 93,151 93,980 94,075 97,117 98,672 1 1 2 3 1 Total equity 9,457 9,898 10,329 10,588 10,603 9,458 9,899 10,331 10,591 10,603 (1) (1) (2) (3) (1) Pro memoria: Gross loans and advances to customers ** 92,142 94,299 94,488 97,707 98,144 92,142 94,299 94,488 97,707 98,144 — — — — — Customer funds 36,849 36,728 36,635 36,531 36,849 36,849 36,728 36,635 36,531 36,849 — — — — — Customer deposits *** 36,848 36,726 36,635 36,531 36,849 36,848 36,726 36,635 36,531 36,849 — — — — — Mutual funds 1 1 — — — 1 1 — — — — — — — —

15 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. United Kingdom EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 1,023 1,029 1,016 1,011 975 1,031 1,039 1,033 1,033 1,001 (8) (10) (17) (22) (26) Net fee income 219 240 230 224 216 242 265 258 257 243 (23) (25) (29) (34) (27) Gains (losses) on financial transactions * 15 44 43 (14) 0 57 64 63 16 19 (42) (19) (20) (30) (19) Other operating income 13 6 12 22 14 18 5 13 26 17 (5) 1 (1) (4) (2) Total income 1,270 1,319 1,300 1,242 1,206 1,349 1,373 1,367 1,332 1,280 (79) (54) (66) (90) (74) Administrative expenses and amortisations (725) (715) (697) (700) (739) (764) (763) (730) (738) (783) 38 49 32 39 44 Net operating income 545 605 603 542 467 586 610 637 593 497 (41) (5) (34) (51) (30) Net loan-loss provisions (66) (36) (26) (43) (61) (66) (37) (26) (44) (64) (0) 1 (1) 2 3 Other gains (losses) and provisions (59) (44) (63) (155) (50) (62) (47) (62) (155) (53) 4 3 (1) (0) 3 Profit before tax 420 524 514 344 357 457 526 549 394 380 (37) (1) (35) (50) (24) Tax on profit (124) (142) (150) (90) (97) (131) (146) (159) (103) (104) 7 4 9 12 7 Profit from continuing operations 297 382 364 254 260 326 380 391 291 276 (29) 2 (27) (37) (17) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 297 382 364 254 260 326 380 391 291 276 (29) 2 (27) (37) (17) Non-controlling interests (6) (7) (6) (5) (5) (6) (7) (6) (5) (5) — — — — — Underlying attributable profit to the parent 290 375 358 249 254 320 372 385 286 271 (29) 2 (27) (37) (17) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 248,730 249,089 248,846 249,991 263,566 252,451 254,386 255,577 257,284 270,409 (3,722) (5,297) (6,731) (7,293) (6,843) Cash, central banks and credit institutions 47,670 53,171 38,199 37,246 37,781 47,675 54,218 41,298 39,843 41,636 (6) (1,047) (3,099) (2,597) (3,854) Debt instruments 25,477 26,457 23,924 26,517 23,713 25,477 26,551 26,914 29,190 26,758 — (94) (2,990) (2,673) (3,044) Other financial assets 9,522 7,152 9,714 594 754 21,861 20,559 20,686 13,397 14,136 (12,339) (13,408) (10,972) (12,804) (13,382) Other asset accounts 10,652 10,156 8,972 9,431 10,260 10,839 10,361 9,187 9,638 10,500 (187) (206) (215) (208) (240) Total assets 342,051 346,024 329,654 323,779 336,075 358,305 366,076 353,661 349,353 363,439 (16,254) (20,052) (24,007) (25,574) (27,364) Customer deposits 220,652 219,001 214,578 208,179 216,849 221,268 219,601 216,426 210,388 219,837 (616) (600) (1,848) (2,209) (2,988) Central banks and credit institutions 15,488 24,044 22,997 25,821 25,240 29,322 41,026 31,021 33,430 32,760 (13,834) (16,982) (8,023) (7,608) (7,520) Marketable debt securities 64,658 66,575 67,877 67,556 67,564 64,658 66,575 67,877 67,556 67,536 — — — — 27 Other financial liabilities 20,676 15,596 4,970 2,097 4,421 21,346 17,280 17,930 16,583 20,497 (670) (1,684) (12,960) (14,486) (16,076) Other liabilities accounts 5,093 4,280 3,850 4,126 4,572 5,132 4,317 3,935 4,181 4,673 (39) (37) (85) (55) (101) Total liabilities 326,567 329,495 314,273 307,779 318,646 341,726 348,799 337,188 332,137 345,303 (15,159) (19,304) (22,916) (24,358) (26,657) Total equity 15,484 16,529 15,382 16,000 17,429 16,579 17,276 16,473 17,216 18,135 (1,094) (748) (1,091) (1,216) (707) Pro memoria: Gross loans and advances to customers ** 235,294 234,185 230,411 228,548 240,377 239,034 239,501 237,116 235,753 246,820 (3,740) (5,316) (6,705) (7,205) (6,443) Customer funds 206,738 204,058 203,330 204,424 209,798 207,354 204,659 205,178 206,630 212,786 (616) (600) (1,848) (2,207) (2,988) Customer deposits *** 198,255 195,664 194,958 196,848 201,517 198,871 196,264 196,806 199,054 204,505 (616) (600) (1,848) (2,207) (2,988) Mutual funds 8,483 8,395 8,372 7,576 8,281 8,483 8,395 8,372 7,576 8,281 — — — — —

16 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. Portugal EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 222 213 211 211 216 222 213 211 211 216 — — — — — Net fee income 98 91 92 96 98 98 91 92 96 98 — — — — — Gains (losses) on financial transactions * 22 36 6 12 50 22 36 6 12 50 — — 0 (0) — Other operating income (0) 6 14 14 (6) (0) 6 14 14 (6) 0 — (0) 0 — Total income 341 346 323 334 357 341 346 323 334 357 — — — — — Administrative expenses and amortisations (159) (165) (157) (162) (157) (158) (165) (157) (162) (157) (1) (1) (1) (1) (1) Net operating income 182 181 165 171 200 183 182 166 172 201 (1) (1) (1) (1) (1) Net loan-loss provisions (8) (0) (11) (12) 13 (8) (0) (11) (12) 13 — 0 — — — Other gains (losses) and provisions (9) (22) 13 36 (20) (9) (22) 13 36 (20) — (0) (0) 0 — Profit before tax 166 159 166 195 193 166 159 167 196 194 (1) (1) (1) (1) (1) Tax on profit (39) (55) (52) (59) (58) (39) (56) (52) (59) (58) 0 0 0 0 0 Profit from continuing operations 127 103 115 136 135 128 104 115 137 136 (0) (0) (0) (0) (0) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 127 103 115 136 135 128 104 115 137 136 (0) (0) (0) (0) (0) Non-controlling interests (1) (1) (1) (1) (0) (1) (1) (1) (1) (0) — — — — — Underlying attributable profit to the parent 127 103 114 136 135 127 103 114 136 135 (0) (0) (0) (0) (0) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 35,722 35,567 35,612 35,470 35,417 35,722 35,567 35,612 35,470 35,417 — — — — — Cash, central banks and credit institutions 2,410 4,362 3,191 3,454 4,193 2,410 4,362 3,191 3,454 4,193 — — — — — Debt instruments 12,058 11,794 11,861 12,303 13,198 12,058 11,794 11,861 12,303 13,198 — — — — — Other financial assets 1,991 1,936 1,941 1,877 1,841 1,991 1,936 1,941 1,877 1,841 — — — — — Other asset accounts 2,257 2,454 2,298 1,904 1,971 2,257 2,454 2,298 1,904 1,971 — — — — — Total assets 54,438 56,112 54,904 55,007 56,620 54,438 56,112 54,904 55,007 56,620 — — — — — Customer deposits 35,114 37,066 37,141 37,217 38,242 35,114 37,066 37,141 37,217 38,242 — — — — — Central banks and credit institutions 9,365 9,041 7,817 8,009 8,156 9,364 9,040 7,816 8,007 8,155 0 1 1 1 0 Marketable debt securities 4,379 4,329 4,309 4,259 4,232 4,379 4,329 4,309 4,259 4,232 — — — — — Other financial liabilities 235 262 243 257 285 235 262 243 257 285 — — — — — Other liabilities accounts 1,238 1,489 1,382 1,197 1,418 1,238 1,489 1,382 1,197 1,418 — — — — — Total liabilities 50,331 52,186 50,890 50,938 52,333 50,330 52,186 50,889 50,937 52,332 0 1 1 1 0 Total equity 4,107 3,926 4,013 4,069 4,287 4,107 3,927 4,014 4,070 4,287 (0) (1) (1) (1) (0) Pro memoria: Gross loans and advances to customers ** 37,418 37,057 37,093 36,568 36,478 37,418 37,057 37,093 36,568 36,478 — — — — — Customer funds 37,241 39,195 39,185 39,143 40,242 37,241 39,195 39,185 39,143 40,242 — — — — — Customer deposits *** 35,114 37,066 37,141 37,217 38,242 35,114 37,066 37,141 37,217 38,242 — — — — — Mutual funds 2,127 2,128 2,045 1,926 2,000 2,127 2,128 2,045 1,926 2,000 — — — — —

17 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. Poland EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 247 240 243 265 281 247 240 243 265 281 — — — — — Net fee income 112 114 111 115 113 112 114 111 115 113 — — 0 (0) — Gains (losses) on financial transactions * 4 16 15 9 18 4 16 15 9 18 — — — (0) — Other operating income (30) 28 (2) 0 (36) (30) 28 (2) 0 (36) — — 0 (0) — Total income 333 398 367 390 377 333 398 367 390 377 — — — — — Administrative expenses and amortisations (154) (163) (157) (165) (173) (154) (162) (156) (165) (172) (1) (1) (1) (1) (1) Net operating income 178 236 210 224 204 179 236 211 225 205 (1) (1) (1) (1) (1) Net loan-loss provisions (46) (41) (33) (41) (43) (46) (41) (33) (41) (43) — — — — — Other gains (losses) and provisions (13) (34) (26) (61) (34) (13) (34) (26) (61) (34) — — — — — Profit before tax 119 160 151 122 127 120 161 151 123 128 (1) (1) (1) (1) (1) Tax on profit (31) (29) (37) (34) (37) (31) (29) (37) (34) (38) 0 0 0 0 0 Profit from continuing operations 89 131 114 88 89 89 132 114 88 90 (1) (1) (1) (1) (1) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 89 131 114 88 89 89 132 114 88 90 (1) (1) (1) (1) (1) Non-controlling interests (26) (39) (34) (27) (28) (26) (39) (34) (27) (28) — — — — — Underlying attributable profit to the parent 63 92 80 61 61 63 93 80 62 62 (1) (1) (1) (1) (1) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 22,328 22,583 23,639 28,164 28,421 22,328 22,583 23,639 28,164 28,421 — — — — — Cash, central banks and credit institutions 1,799 1,617 2,128 3,260 2,671 1,799 1,617 2,128 3,260 2,671 — — — — — Debt instruments 7,452 8,404 9,718 10,570 11,262 7,452 8,404 9,718 10,570 11,262 — — — — — Other financial assets 502 560 464 534 544 502 560 464 534 544 — — — — — Other asset accounts 1,041 1,023 1,083 1,140 1,309 1,041 1,023 1,083 1,140 1,309 — — — — — Total assets 33,122 34,188 37,031 43,669 44,208 33,122 34,188 37,031 43,669 44,208 — — — — — Customer deposits 24,987 25,668 28,026 33,417 32,439 24,987 25,668 28,026 33,417 32,439 — — — — — Central banks and credit institutions 1,611 1,710 1,642 2,165 3,348 1,610 1,708 1,641 2,163 3,348 1 1 2 2 1 Marketable debt securities 639 1,010 1,527 1,789 1,794 639 1,010 1,527 1,789 1,794 — — — — — Other financial liabilities 324 428 457 558 749 324 428 457 558 749 — — — — — Other liabilities accounts 706 767 734 809 820 706 767 734 809 820 — — — — — Total liabilities 28,267 29,582 32,385 38,738 39,150 28,266 29,581 32,384 38,736 39,149 1 1 2 2 1 Total equity 4,855 4,605 4,646 4,930 5,058 4,856 4,607 4,648 4,933 5,058 (1) (1) (2) (2) (1) Pro memoria: Gross loans and advances to customers ** 23,161 23,388 24,356 29,033 29,319 23,161 23,388 24,356 29,033 29,319 — — — — — Customer funds 28,109 28,751 30,011 35,554 35,186 28,109 28,751 30,011 35,554 35,186 — — — — — Customer deposits *** 24,169 24,993 26,212 31,542 31,117 24,169 24,993 26,212 31,542 31,117 — — — — — Mutual funds 3,941 3,757 3,799 4,012 4,069 3,941 3,757 3,799 4,012 4,069 — — — — —

18 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. Rest of Europe EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 127 71 111 147 139 59 39 32 40 34 67 32 79 108 105 Net fee income 60 77 64 71 62 33 53 35 40 42 26 24 29 31 19 Gains (losses) on financial transactions * 157 (103) 18 77 (4) 29 (2) 30 124 25 128 (101) (12) (47) (29) Other operating income 39 76 14 62 64 11 10 4 7 7 29 66 9 55 57 Total income 382 122 207 357 261 132 101 101 211 109 250 21 106 146 152 Administrative expenses and amortisations (181) (181) (182) (174) (200) (128) (137) (139) (131) (133) (53) (44) (44) (43) (67) Net operating income 202 (59) 24 183 61 4 (36) (38) 81 (24) 197 (23) 62 102 85 Net loan-loss provisions 0 (36) 1 (24) (2) (10) (60) (16) (34) (23) 10 23 17 10 21 Other gains (losses) and provisions (7) (4) (0) (28) (7) (32) (17) (32) (19) (37) 24 13 32 (9) 30 Profit before tax 194 (99) 25 131 52 (37) (113) (86) 28 (84) 231 14 110 103 136 Tax on profit (62) 13 (10) (35) (19) 1 22 21 (6) 21 (63) (9) (32) (30) (40) Profit from continuing operations 132 (86) 15 96 33 (36) (91) (64) 22 (63) 168 5 79 73 96 Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 132 (86) 15 96 33 (36) (91) (64) 22 (63) 168 5 79 73 96 Non-controlling interests (0) (1) 0 (2) (1) 0 (0) 1 (1) 9 (0) (1) (0) (0) (10) Underlying attributable profit to the parent 132 (87) 15 94 32 (36) (91) (63) 21 (54) 168 4 79 73 86 NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 34,068 33,443 33,905 34,874 38,465 12,487 12,935 14,086 17,244 18,954 21,581 20,507 19,819 17,631 19,510 Cash, central banks and credit institutions 39,871 37,090 47,863 43,141 50,182 10,644 12,928 12,381 12,788 13,713 29,227 24,163 35,482 30,353 36,469 Debt instruments 16,655 15,272 18,367 16,657 22,420 1,637 1,341 1,391 2,112 1,964 15,018 13,931 16,976 14,545 20,456 Other financial assets 44,160 45,237 39,994 43,713 49,352 866 818 827 844 630 43,294 44,419 39,167 42,869 48,721 Other asset accounts 2,930 3,186 3,213 3,189 2,808 8,461 8,746 8,590 8,434 6,531 (5,530) (5,560) (5,377) (5,245) (3,724) Total assets 137,685 134,228 143,341 141,574 163,226 34,094 36,768 37,276 41,421 41,792 103,590 97,460 106,066 100,153 121,433 Customer deposits 13,289 14,130 14,744 18,071 20,366 5,307 5,600 6,094 7,116 8,136 7,983 8,530 8,650 10,955 12,230 Central banks and credit institutions 85,871 79,571 80,644 75,660 93,761 24,635 25,906 26,143 29,771 28,878 61,236 53,665 54,501 45,889 64,883 Marketable debt securities 47 136 715 61 103 16 125 699 81 146 31 10 16 (20) (44) Other financial liabilities 35,019 36,365 43,409 43,787 45,590 832 623 473 502 548 34,187 35,742 42,936 43,285 45,042 Other liabilities accounts 427 418 479 379 375 346 447 434 424 360 80 (29) 44 (44) 15 Total liabilities 134,653 130,619 139,990 137,959 160,195 31,136 32,701 33,843 37,893 38,068 103,517 97,918 106,147 100,066 122,126 Total equity 3,031 3,608 3,351 3,615 3,031 2,958 4,066 3,432 3,528 3,724 73 (458) (81) 87 (693) Pro memoria: Gross loans and advances to customers ** 24,023 26,587 28,971 31,061 33,851 13,420 13,785 14,850 17,855 19,522 10,603 12,802 14,121 13,206 14,330 Customer funds 16,853 17,360 17,945 20,381 23,517 9,008 9,073 9,502 10,334 11,606 7,845 8,287 8,443 10,048 11,911 Customer deposits *** 13,155 13,891 14,538 17,163 20,047 5,306 5,600 6,094 7,115 8,136 7,849 8,291 8,443 10,048 11,911 Mutual funds 3,698 3,469 3,407 3,218 3,470 3,701 3,473 3,407 3,218 3,470 (4) (4) (0) 0 0

19 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. NORTH AMERICA (North America vs United States + Mexico) EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 1,869 1,933 2,065 2,286 2,173 1,869 1,933 2,065 2,286 2,173 — — — — — Net fee income 402 408 407 399 439 402 408 407 399 439 — — — — — Gains (losses) on financial transactions * 34 78 49 13 12 34 78 49 13 12 — — — (0) 0 Other operating income 104 119 145 166 130 104 119 145 166 130 — — — — — Total income 2,409 2,538 2,666 2,863 2,753 2,409 2,538 2,666 2,863 2,753 — — — — — Administrative expenses and amortisations (1,078) (1,103) (1,134) (1,173) (1,172) (1,075) (1,100) (1,131) (1,171) (1,169) (3) (3) (3) (3) (3) Net operating income 1,331 1,435 1,532 1,690 1,581 1,334 1,438 1,534 1,693 1,584 (3) (3) (3) (3) (3) Net loan-loss provisions (779) (634) (876) (1,159) (804) (779) (634) (876) (1,159) (804) — — — — — Other gains (losses) and provisions (26) (62) (74) (40) (64) (26) (62) (74) (40) (64) — — — — — Profit before tax 526 739 581 491 713 529 742 584 493 716 (3) (3) (3) (3) (3) Tax on profit (129) (204) (158) (108) (188) (130) (205) (159) (108) (189) 1 1 1 1 1 Profit from continuing operations 397 535 423 383 526 399 537 425 385 528 (2) (2) (2) (2) (2) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 397 535 423 383 526 399 537 425 385 528 (2) (2) (2) (2) (2) Non-controlling interests (99) (142) (105) (87) (139) (99) (142) (105) (87) (139) — — — — — Underlying attributable profit to the parent 298 393 318 296 386 300 394 320 298 389 (2) (2) (2) (2) (2) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 97,335 104,619 111,342 116,196 124,379 97,335 104,619 111,342 116,196 124,379 — — — — — Cash, central banks and credit institutions 23,192 24,977 25,761 28,845 32,722 23,192 24,977 25,761 28,845 32,722 — — — — 0 Debt instruments 25,883 26,663 28,835 27,302 24,576 25,883 26,663 28,835 27,302 24,576 — — — — — Other financial assets 8,409 10,492 10,651 9,974 8,464 8,409 10,492 10,651 9,974 8,464 — — — — (0) Other asset accounts 14,534 16,069 17,552 18,602 20,217 14,534 16,069 17,552 18,602 20,217 — — — — — Total assets 169,352 182,819 194,141 200,919 210,358 169,352 182,819 194,141 200,919 210,358 — — — — — Customer deposits 83,109 87,315 93,213 91,896 100,536 83,109 87,315 93,213 91,896 100,536 — — — — — Central banks and credit institutions 20,124 21,794 24,555 26,048 23,373 20,122 21,790 24,550 26,041 23,371 2 4 6 7 2 Marketable debt securities 31,034 34,448 36,957 43,758 46,669 31,034 34,448 36,957 43,758 46,669 — — — — — Other financial liabilities 9,508 11,973 11,736 11,379 10,907 9,508 11,973 11,736 11,379 10,907 — — — — — Other liabilities accounts 5,141 5,797 5,848 5,966 5,631 5,141 5,797 5,848 5,966 5,631 — — — — — Total liabilities 148,916 161,327 172,309 179,046 187,116 148,914 161,323 172,303 179,039 187,114 2 4 6 7 2 Total equity 20,436 21,493 21,832 21,872 23,242 20,438 21,496 21,838 21,880 23,244 (2) (4) (6) (7) (2) Pro memoria: Gross loans and advances to customers ** 100,978 108,775 112,539 114,888 120,625 100,978 108,775 112,539 114,888 120,625 — — — — — Customer funds 96,761 101,250 102,407 102,869 109,592 96,761 101,250 102,407 102,869 109,592 — — — — — Customer deposits *** 78,179 82,226 82,722 84,769 89,287 78,179 82,226 82,722 84,769 89,287 — — — — — Mutual funds 18,582 19,023 19,686 18,100 20,305 18,582 19,023 19,686 18,100 20,305 — — — — —

20 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. United States EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 1,221 1,281 1,337 1,553 1,407 1,221 1,281 1,337 1,553 1,407 — — — — — Net fee income 214 219 208 217 234 214 219 208 217 234 — — — — — Gains (losses) on financial transactions * 16 23 22 11 16 16 23 22 11 16 — — — — — Other operating income 127 147 169 185 158 127 147 169 185 158 — — — — — Total income 1,578 1,670 1,735 1,967 1,815 1,578 1,670 1,735 1,967 1,815 — — — — — Administrative expenses and amortisations (736) (738) (749) (796) (775) (735) (737) (748) (795) (774) (1) (1) (1) (1) (1) Net operating income 842 931 986 1,171 1,039 843 932 987 1,172 1,040 (1) (1) (1) (1) (1) Net loan-loss provisions (579) (445) (649) (945) (611) (579) (445) (649) (945) (611) — — — — — Other gains (losses) and provisions (23) (50) (69) (57) (58) (23) (50) (69) (57) (58) — — — — — Profit before tax 240 436 268 169 370 241 437 269 170 371 (1) (1) (1) (1) (1) Tax on profit (67) (138) (93) (47) (110) (67) (139) (94) (47) (111) 0 0 0 0 0 Profit from continuing operations 173 297 174 122 260 174 298 175 123 260 (1) (1) (1) (1) (1) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 173 297 174 122 260 174 298 175 123 260 (1) (1) (1) (1) (1) Non-controlling interests (49) (88) (50) (31) (78) (49) (88) (50) (31) (78) — — — — — Underlying attributable profit to the parent 124 209 124 91 181 125 210 125 92 182 (1) (1) (1) (1) (1) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 69,096 76,188 79,897 85,564 91,324 69,096 76,188 79,897 85,564 91,324 — — — — — Cash, central banks and credit institutions 11,695 11,661 14,299 16,442 18,067 11,695 11,661 14,299 16,442 18,067 — — — — — Debt instruments 13,656 14,349 13,252 13,160 13,433 13,656 14,349 13,252 13,160 13,433 — — — — — Other financial assets 3,204 4,316 5,102 4,291 3,546 3,204 4,316 5,102 4,291 3,546 — — — — — Other asset accounts 11,924 13,307 14,644 15,585 16,951 11,924 13,307 14,644 15,585 16,951 — — — — — Total assets 109,575 119,821 127,194 135,043 143,321 109,575 119,821 127,194 135,043 143,321 — — — — — Customer deposits 50,875 54,005 58,910 57,568 64,849 50,875 54,005 58,910 57,568 64,849 — — — — — Central banks and credit institutions 11,964 13,358 13,155 16,507 13,046 11,963 13,356 13,153 16,505 13,046 1 1 2 3 1 Marketable debt securities 25,479 28,517 30,712 37,564 40,833 25,479 28,517 30,712 37,564 40,833 — — — — — Other financial liabilities 2,738 3,957 4,414 3,098 3,644 2,738 3,957 4,414 3,098 3,644 — — — — — Other liabilities accounts 3,298 3,630 3,820 3,798 3,688 3,298 3,630 3,820 3,798 3,688 — — — — — Total liabilities 94,354 103,467 111,011 118,535 126,061 94,353 103,466 111,009 118,532 126,060 1 1 2 3 1 Total equity 15,221 16,353 16,184 16,508 17,260 15,222 16,355 16,186 16,511 17,261 (1) (1) (2) (3) (1) Pro memoria: Gross loans and advances to customers ** 72,285 79,562 80,686 83,696 87,759 72,285 79,562 80,686 83,696 87,759 — — — — — Customer funds 58,666 62,210 62,000 64,239 67,968 58,666 62,210 62,000 64,239 67,968 — — — — — Customer deposits *** 50,684 53,775 53,548 56,064 58,873 50,684 53,775 53,548 56,064 58,873 — — — — — Mutual funds 7,981 8,436 8,453 8,176 9,095 7,981 8,436 8,453 8,176 9,095 — — — — —

21 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. Mexico EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 649 653 728 733 766 649 653 728 733 766 — — 0 — — Net fee income 187 188 199 181 204 187 188 199 181 204 — — — — — Gains (losses) on financial transactions * 18 55 27 2 (4) 18 55 27 2 (4) — — 0 (0) 0 Other operating income (23) (28) (24) (20) (28) (23) (28) (24) (20) (28) — — 0 (0) — Total income 831 868 931 897 939 831 868 931 897 939 — — 0 — — Administrative expenses and amortisations (342) (364) (385) (378) (397) (340) (363) (384) (376) (395) (2) (2) (2) (2) (2) Net operating income 489 504 546 519 542 491 505 547 521 544 (2) (2) (2) (2) (2) Net loan-loss provisions (200) (189) (227) (215) (193) (200) (189) (227) (215) (193) — — (0) 0 — Other gains (losses) and provisions (3) (12) (5) 17 (6) (3) (12) (5) 17 (6) — — — — — Profit before tax 286 303 313 321 343 288 305 315 323 345 (2) (2) (2) (2) (2) Tax on profit (62) (66) (64) (61) (77) (63) (67) (65) (61) (78) 0 0 0 0 1 Profit from continuing operations 224 237 249 261 266 225 238 250 262 268 (1) (1) (1) (1) (1) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 224 237 249 261 266 225 238 250 262 268 (1) (1) (1) (1) (1) Non-controlling interests (50) (54) (55) (56) (61) (50) (54) (55) (56) (61) — — — — — Underlying attributable profit to the parent 173 183 194 205 205 175 184 195 206 206 (1) (1) (1) (1) (1) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 28,238 28,431 31,445 30,632 33,055 28,238 28,431 31,445 30,632 33,055 — — — — — Cash, central banks and credit institutions 11,497 13,315 11,463 12,403 14,655 11,497 13,315 11,463 12,403 14,655 — — — — 0 Debt instruments 12,227 12,314 15,583 14,142 11,144 12,227 12,314 15,583 14,142 11,144 — — — — — Other financial assets 5,205 6,176 5,549 5,683 4,918 5,205 6,176 5,549 5,683 4,918 — — — — (0) Other asset accounts 2,610 2,762 2,907 3,016 3,266 2,610 2,762 2,907 3,016 3,266 — — — — — Total assets 59,778 62,999 66,946 65,876 67,037 59,778 62,999 66,946 65,876 67,037 — — — — — Customer deposits 32,235 33,310 34,303 34,327 35,687 32,235 33,310 34,303 34,327 35,687 — — — — — Central banks and credit institutions 8,160 8,436 11,400 9,541 10,327 8,159 8,434 11,397 9,536 10,326 1 2 3 5 1 Marketable debt securities 5,555 5,931 6,244 6,194 5,835 5,555 5,931 6,244 6,194 5,835 — — — — — Other financial liabilities 6,770 8,016 7,323 8,281 7,264 6,770 8,016 7,323 8,281 7,264 — — — — — Other liabilities accounts 1,843 2,167 2,028 2,168 1,942 1,843 2,167 2,028 2,168 1,942 — — — — — Total liabilities 54,563 57,859 61,298 60,512 61,055 54,562 57,857 61,294 60,507 61,054 1 2 3 5 1 Total equity 5,215 5,139 5,649 5,364 5,982 5,216 5,142 5,652 5,369 5,983 (1) (2) (3) (5) (1) Pro memoria: Gross loans and advances to customers ** 28,693 29,212 31,853 31,192 32,866 28,693 29,212 31,853 31,192 32,866 — — — — — Customer funds 38,095 39,039 40,407 38,630 41,624 38,095 39,039 40,407 38,630 41,624 — — — — — Customer deposits *** 27,494 28,451 29,174 28,705 30,414 27,494 28,451 29,174 28,705 30,414 — — — — — Mutual funds 10,601 10,588 11,233 9,925 11,210 10,601 10,588 11,233 9,925 11,210 — — — — —

22 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. SOUTH AMERICA (South America vs Latin America - Mexico) EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 3,298 3,259 2,952 3,382 3,222 3,298 3,259 2,952 3,382 3,222 — — — — — Net fee income 1,189 1,151 903 1,254 1,178 1,189 1,151 903 1,254 1,178 — (0) 0 (0) — Gains (losses) on financial transactions * 125 131 105 138 160 125 131 105 138 160 — — — (0) — Other operating income (2) 0 (77) (134) (72) (2) 0 (77) (134) (72) 0 (0) — — — Total income 4,610 4,541 3,883 4,640 4,487 4,610 4,541 3,883 4,640 4,487 — — 0 — — Administrative expenses and amortisations (1,716) (1,645) (1,353) (1,843) (1,645) (1,710) (1,639) (1,347) (1,837) (1,638) (6) (6) (6) (6) (7) Net operating income 2,894 2,896 2,530 2,797 2,842 2,900 2,902 2,535 2,803 2,849 (6) (6) (6) (6) (7) Net loan-loss provisions (1,010) (948) (810) (968) (903) (1,010) (948) (810) (968) (903) — — — — — Other gains (losses) and provisions (152) (181) (153) (177) (154) (152) (181) (153) (177) (154) — — — — — Profit before tax 1,732 1,767 1,566 1,652 1,785 1,738 1,773 1,572 1,658 1,792 (6) (6) (6) (6) (7) Tax on profit (655) (683) (671) (632) (692) (657) (685) (673) (634) (694) 2 2 2 2 2 Profit from continuing operations 1,077 1,084 895 1,020 1,093 1,081 1,088 899 1,024 1,098 (4) (4) (4) (4) (5) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 1,077 1,084 895 1,020 1,093 1,081 1,088 899 1,024 1,098 (4) (4) (4) (4) (5) Non-controlling interests (157) (158) (147) (162) (167) (157) (158) (147) (162) (167) — — — — — Underlying attributable profit to the parent 920 926 747 858 926 924 930 751 862 931 (4) (4) (4) (4) (5) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 121,181 115,374 114,790 119,912 123,313 121,181 115,374 114,790 119,912 123,313 — — — — — Cash, central banks and credit institutions 43,900 44,482 45,918 48,318 44,423 43,900 44,482 45,918 48,318 44,423 — — — — — Debt instruments 49,048 44,008 39,869 45,225 45,992 49,048 44,008 39,869 45,225 45,992 — — — — — Other financial assets 9,371 8,449 8,027 9,311 8,960 9,371 8,449 8,027 9,311 8,960 — — — — — Other asset accounts 14,804 14,077 13,776 14,715 15,754 14,804 14,077 13,776 14,715 15,754 — — — — — Total assets 238,304 226,391 222,379 237,480 238,442 238,304 226,391 222,379 237,480 238,442 — — — — — Customer deposits 111,589 108,520 107,777 108,248 111,494 111,589 108,520 107,777 108,248 111,494 — — — — — Central banks and credit institutions 35,056 38,134 33,546 38,584 38,807 35,051 38,126 33,534 38,568 38,802 4 8 12 17 5 Marketable debt securities 30,912 28,336 28,644 31,504 31,005 30,912 28,336 28,644 31,504 31,005 — — — — — Other financial liabilities 29,008 23,262 23,981 28,570 25,908 29,008 23,262 23,981 28,570 25,908 — — — — — Other liabilities accounts 9,190 7,700 7,899 8,699 8,908 9,190 7,700 7,899 8,699 8,908 — — — — — Total liabilities 215,756 205,951 201,847 215,605 216,121 215,752 205,943 201,835 215,588 216,117 4 8 12 17 5 Total equity 22,548 20,439 20,532 21,875 22,321 22,552 20,448 20,544 21,892 22,326 (4) (8) (12) (17) (5) Pro memoria: Gross loans and advances to customers ** 126,854 120,755 120,094 125,830 129,036 126,860 120,755 120,094 125,830 129,036 (5) — — — — Customer funds 163,651 156,749 153,633 158,968 164,027 163,651 156,749 153,633 158,968 164,027 — — — — — Customer deposits *** 97,757 95,318 93,120 97,325 99,543 97,757 95,318 93,120 97,325 99,543 — — — — — Mutual funds 65,894 61,431 60,513 61,643 64,484 65,894 61,431 60,513 61,643 64,484 — — — — —

23 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. Brazil EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 2,482 2,424 2,377 2,475 2,459 2,482 2,424 2,377 2,475 2,459 — — 0 — — Net fee income 920 872 776 929 931 920 872 776 929 931 — (0) 0 (0) — Gains (losses) on financial transactions * 50 33 32 21 58 50 33 32 21 58 — (0) 0 (0) — Other operating income (8) (5) (4) (29) (36) (8) (5) (4) (29) (36) 0 (0) (0) (0) — Total income 3,445 3,323 3,180 3,396 3,411 3,445 3,323 3,180 3,396 3,411 — (0) 0 — — Administrative expenses and amortisations (1,169) (1,100) (1,036) (1,196) (1,125) (1,165) (1,095) (1,031) (1,191) (1,119) (5) (5) (5) (5) (5) Net operating income 2,276 2,224 2,145 2,201 2,286 2,280 2,228 2,149 2,205 2,292 (5) (5) (5) (5) (5) Net loan-loss provisions (822) (750) (665) (726) (710) (822) (750) (665) (726) (710) — — — — — Other gains (losses) and provisions (154) (170) (174) (198) (167) (154) (170) (174) (198) (167) — — — — — Profit before tax 1,300 1,303 1,306 1,276 1,409 1,304 1,308 1,310 1,281 1,414 (5) (5) (5) (5) (5) Tax on profit (542) (577) (611) (528) (592) (544) (578) (612) (529) (594) 1 1 1 1 2 Profit from continuing operations 758 726 695 749 816 761 730 698 752 820 (3) (3) (3) (3) (4) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 758 726 695 749 816 761 730 698 752 820 (3) (3) (3) (3) (4) Non-controlling interests (84) (83) (79) (89) (96) (84) (83) (79) (89) (96) — — — — — Underlying attributable profit to the parent 674 643 615 659 721 677 647 619 663 724 (3) (3) (3) (3) (4) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 69,623 65,258 65,006 70,850 71,724 69,623 65,258 65,006 70,850 71,724 — — — — — Cash, central banks and credit institutions 33,399 34,614 35,914 37,015 33,329 33,399 34,614 35,914 37,015 33,329 — — — — — Debt instruments 42,820 38,191 35,015 40,718 41,047 42,820 38,191 35,015 40,718 41,047 — — — — — Other financial assets 6,373 5,481 5,184 6,133 5,671 6,373 5,481 5,184 6,133 5,671 — — — — — Other asset accounts 11,769 11,436 11,145 11,320 11,856 11,769 11,436 11,145 11,320 11,856 — — — — — Total assets 163,984 154,981 152,263 166,036 163,627 163,984 154,981 152,263 166,036 163,627 — — — — — Customer deposits 68,667 67,504 69,052 68,306 70,257 68,667 67,504 69,052 68,306 70,257 — — — — — Central banks and credit institutions 27,753 30,644 24,902 29,771 29,669 27,750 30,637 24,892 29,758 29,666 3 6 9 13 4 Marketable debt securities 20,563 17,818 18,164 21,218 19,996 20,563 17,818 18,164 21,218 19,996 — — — — — Other financial liabilities 24,333 18,510 19,525 24,241 21,278 24,333 18,510 19,525 24,241 21,278 — — — — — Other liabilities accounts 7,392 6,323 6,323 7,237 7,231 7,392 6,323 6,323 7,237 7,231 — — — — — Total liabilities 148,708 140,798 137,965 150,773 148,432 148,705 140,792 137,956 150,760 148,428 3 6 9 13 4 Total equity 15,276 14,183 14,298 15,264 15,195 15,279 14,189 14,308 15,276 15,199 (3) (6) (9) (13) (4) Pro memoria: Gross loans and advances to customers ** 74,071 69,475 69,190 75,282 76,336 74,071 69,475 69,190 75,282 76,336 — — — — — Customer funds 110,178 106,121 106,612 110,243 113,769 110,178 106,121 106,612 110,243 113,769 — — — — — Customer deposits *** 54,890 54,344 54,432 57,432 58,368 54,890 54,344 54,432 57,432 58,368 — — — — — Mutual funds 55,288 51,777 52,181 52,811 55,400 55,288 51,777 52,181 52,811 55,400 — — — — —

24 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. Chile EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 490 495 481 477 440 490 495 481 477 440 — — — (0) — Net fee income 111 117 101 95 103 111 117 101 95 103 — — — — — Gains (losses) on financial transactions * 30 28 45 46 54 30 28 45 46 54 — — — — — Other operating income 10 2 4 3 2 10 2 4 3 2 — 0 (0) (0) — Total income 640 642 632 622 600 640 642 632 622 600 — — — — — Administrative expenses and amortisations (259) (273) (257) (259) (255) (258) (272) (257) (258) (255) (1) (1) (1) (1) (1) Net operating income 381 369 374 363 344 382 370 375 364 345 (1) (1) (1) (1) (1) Net loan-loss provisions (121) (115) (117) (120) (102) (121) (115) (117) (120) (102) — — — — — Other gains (losses) and provisions 22 32 19 31 37 22 32 19 31 37 — — — — — Profit before tax 282 287 276 274 279 282 287 276 275 280 (1) (1) (1) (1) (1) Tax on profit (59) (56) (56) (48) (60) (60) (56) (56) (49) (60) 0 0 0 0 0 Profit from continuing operations 222 231 220 226 219 223 232 221 226 220 (1) (1) (1) (1) (1) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 222 231 220 226 219 223 232 221 226 220 (1) (1) (1) (1) (1) Non-controlling interests (72) (74) (68) (73) (71) (72) (74) (68) (73) (71) — — — — — Underlying attributable profit to the parent 150 157 152 153 148 151 158 153 153 149 (1) (1) (1) (1) (1) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 37,804 38,239 38,971 37,908 39,656 37,804 38,239 38,971 37,908 39,656 — — — — — Cash, central banks and credit institutions 4,015 3,892 3,829 4,247 4,005 4,015 3,892 3,829 4,247 4,005 — — — — — Debt instruments 4,253 4,191 3,761 3,106 3,781 4,253 4,191 3,761 3,106 3,781 — — — — — Other financial assets 2,958 2,933 2,814 3,164 3,166 2,958 2,933 2,814 3,164 3,166 — — — — — Other asset accounts 2,120 1,830 1,862 2,486 2,908 2,120 1,830 1,862 2,486 2,908 — — — — — Total assets 51,150 51,084 51,236 50,911 53,517 51,150 51,084 51,236 50,911 53,517 — — — — — Customer deposits 26,392 26,533 25,432 25,908 26,746 26,392 26,533 25,432 25,908 26,746 — — — — — Central banks and credit institutions 4,758 5,242 6,186 5,869 5,982 4,757 5,241 6,184 5,867 5,981 1 1 2 2 1 Marketable debt securities 9,817 9,931 10,051 9,806 10,703 9,817 9,931 10,051 9,806 10,703 — — — — — Other financial liabilities 3,747 3,896 3,757 3,535 3,730 3,747 3,896 3,757 3,535 3,730 — — — — — Other liabilities accounts 1,324 901 1,058 919 1,059 1,324 901 1,058 919 1,059 — — — — — Total liabilities 46,038 46,503 46,483 46,037 48,220 46,038 46,502 46,481 46,035 48,220 1 1 2 2 1 Total equity 5,111 4,581 4,753 4,874 5,297 5,112 4,582 4,755 4,876 5,297 (1) (1) (2) (2) (1) Pro memoria: Gross loans and advances to customers ** 38,995 39,396 40,123 39,019 40,795 38,995 39,396 40,123 39,019 40,795 — — — — — Customer funds 33,885 34,126 32,479 33,279 34,166 33,885 34,126 32,479 33,279 34,166 — — — — — Customer deposits *** 26,337 26,490 25,395 25,860 26,684 26,337 26,490 25,395 25,860 26,684 — — — — — Mutual funds 7,548 7,636 7,084 7,419 7,482 7,548 7,636 7,084 7,419 7,482 — — — — —

25 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. Rest of South America EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 326 339 94 430 322 326 339 94 430 322 — — (0) — — Net fee income 158 163 25 230 144 158 163 25 230 144 — (0) 0 (0) 0 Gains (losses) on financial transactions * 44 71 28 70 48 44 71 28 70 48 — — (0) — — Other operating income (3) 3 (77) (108) (38) (3) 3 (77) (108) (38) (0) (0) 0 — — Total income 525 576 71 622 477 525 576 71 622 477 — — 0 — 0 Administrative expenses and amortisations (288) (273) (60) (389) (265) (288) (272) (59) (389) (264) (1) (1) (1) (1) (1) Net operating income 237 304 11 233 212 237 304 11 233 212 (1) (1) (1) (1) (1) Net loan-loss provisions (67) (84) (29) (122) (91) (67) (84) (29) (122) (91) — — 0 (0) — Other gains (losses) and provisions (20) (43) 2 (9) (24) (20) (43) 2 (9) (24) — — 0 0 — Profit before tax 150 177 (16) 102 97 151 178 (15) 103 98 (1) (1) (1) (1) (1) Tax on profit (53) (51) (4) (56) (39) (53) (51) (5) (56) (40) 0 0 0 0 0 Profit from continuing operations 97 126 (20) 46 57 98 127 (20) 46 58 (0) (0) (0) (0) (1) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 97 126 (20) 46 57 98 127 (20) 46 58 (0) (0) (0) (0) (1) Non-controlling interests (1) (1) (0) (0) (1) (1) (1) (0) (0) (1) 0 0 0 (0) 0 Underlying attributable profit to the parent 96 126 (20) 45 57 97 126 (20) 46 58 (0) (0) (0) (0) (1) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 13,754 11,877 10,813 11,153 11,932 13,754 11,877 10,813 11,153 11,932 0 (0) — (0) 0 Cash, central banks and credit institutions 6,486 5,977 6,176 7,056 7,089 6,486 5,977 6,176 7,056 7,089 0 — (0) 0 — Debt instruments 1,975 1,627 1,093 1,400 1,163 1,975 1,627 1,093 1,400 1,163 (0) — 0 0 (0) Other financial assets 40 34 29 14 123 40 34 29 14 123 (0) 0 0 (0) 0 Other asset accounts 916 811 769 908 991 916 811 769 908 991 0 0 — (0) 0 Total assets 23,170 20,325 18,879 20,533 21,298 23,170 20,325 18,879 20,533 21,298 0 — 0 (0) — Customer deposits 16,530 14,483 13,293 14,033 14,491 16,530 14,483 13,293 14,033 14,491 (0) (0) — 0 0 Central banks and credit institutions 2,545 2,248 2,459 2,945 3,155 2,544 2,247 2,457 2,943 3,155 0 1 1 2 1 Marketable debt securities 532 587 429 479 306 532 587 429 479 306 0 (0) — (0) (0) Other financial liabilities 929 855 699 794 900 929 855 699 794 900 (0) (0) (0) 0 0 Other liabilities accounts 473 476 518 543 617 473 476 518 543 617 — 0 — 0 — Total liabilities 21,009 18,650 17,399 18,795 19,469 21,009 18,649 17,397 18,793 19,469 0 1 1 2 1 Total equity 2,161 1,676 1,481 1,738 1,829 2,161 1,677 1,482 1,740 1,830 (0) (1) (1) (2) (1) Pro memoria: Gross loans and advances to customers ** 13,788 11,884 10,781 11,530 11,905 13,793 11,884 10,781 11,530 11,905 (5) (0) 0 (0) — Customer funds 19,587 16,501 14,541 15,447 16,092 19,587 16,501 14,541 15,447 16,092 — — — 0 0 Customer deposits *** 16,530 14,483 13,293 14,033 14,491 16,530 14,483 13,293 14,033 14,491 — — — — — Mutual funds 3,057 2,018 1,248 1,413 1,601 3,057 2,018 1,248 1,413 1,601 — 0 0 0 0

26 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. SANTANDER GLOBAL PLATFORM EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 18 20 20 20 22 18 20 20 20 22 Net fee income 1 1 1 4 2 1 1 1 4 2 Gains (losses) on financial transactions * 0 0 0 (0) (1) 0 0 0 (0) (1) Other operating income (4) (3) (3) (2) (4) (4) (3) (3) (2) (4) Total income 16 18 19 21 19 16 18 19 21 19 Administrative expenses and amortisations (23) (39) (32) (49) (41) (23) (39) (32) (49) (41) Net operating income (7) (21) (13) (28) (22) (7) (21) (13) (28) (22) Net loan-loss provisions 0 (0) (0) (0) (0) 0 (0) (0) (0) (0) Other gains (losses) and provisions (1) (0) (1) (0) (1) (1) (0) (1) (0) (1) Profit before tax (7) (21) (13) (28) (23) (7) (21) (13) (28) (23) Tax on profit (1) 7 4 7 12 (1) 7 4 7 12 Profit from continuing operations (9) (14) (10) (22) (11) (9) (14) (10) (22) (11) Net profit from discontinued operations — — — — — — — — — — Consolidated profit (9) (14) (10) (22) (11) (9) (14) (10) (22) (11) Non-controlling interests — — — — — — — — — — Underlying attributable profit to the parent (9) (14) (10) (22) (11) (9) (14) (10) (22) (11) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 130 193 252 337 417 130 193 252 337 417 Cash, central banks and credit institutions 7,343 7,567 7,778 8,168 8,673 7,343 7,567 7,778 8,168 8,673 Debt instruments — — — — — — — — — — Other financial assets 102 139 133 146 152 102 139 133 146 152 Other asset accounts 77 91 110 130 129 77 91 110 130 129 Total assets 7,652 7,990 8,273 8,781 9,370 7,652 7,990 8,273 8,781 9,370 Customer deposits 7,188 7,477 7,767 8,284 8,804 7,188 7,477 7,767 8,284 8,804 Central banks and credit institutions 74 83 66 111 75 74 83 66 111 75 Marketable debt securities — — — — — — — — — — Other financial liabilities 26 45 33 38 41 26 45 33 38 41 Other liabilities accounts 49 131 131 59 60 49 131 131 59 60 Total liabilities 7,337 7,736 7,997 8,492 8,980 7,337 7,736 7,997 8,492 8,980 Total equity 315 254 276 289 390 315 254 276 289 390 Pro memoria: Gross loans and advances to customers ** 132 196 255 340 420 Customer funds 7,795 8,082 8,170 8,650 9,183 Customer deposits *** 7,188 7,477 7,767 8,284 8,804 Mutual funds 607 605 403 367 379

27 (*).- Includes exchange differences. (**).- Excluding reverse repos. (***).- Excluding repos. CORPORATE CENTRE EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income (234) (243) (251) (259) (296) (224) (233) (241) (249) (284) (10) (10) (10) (10) (12) Net fee income (9) (9) (24) (28) (14) (9) (9) (24) (28) (11) (0) (0) (0) (0) (3) Gains (losses) on financial transactions * 12 (8) 10 (4) (79) 12 (8) 10 (4) (79) 0 (0) 0 (0) — Other operating income (5) 0 (1) (6) (11) (6) (1) (2) (14) (10) 1 1 1 8 (1) Total income (236) (258) (266) (297) (399) (227) (250) (257) (295) (384) (9) (9) (9) (2) (15) Administrative expenses and amortisations (105) (107) (107) (106) (97) (121) (122) (123) (128) (119) 16 16 16 22 22 Net operating income (341) (365) (373) (403) (497) (348) (372) (380) (423) (503) 6 7 7 20 7 Net loan-loss provisions (37) (30) (28) (21) (8) (37) (30) (28) (21) (9) — 0 0 (0) 1 Other gains (losses) and provisions (43) (50) (55) 47 (55) (43) (50) (55) 47 (37) — 0 0 (0) (18) Profit before tax (420) (446) (456) (377) (559) (427) (452) (463) (397) (549) 6 7 7 20 (10) Tax on profit 5 (23) 6 26 33 6 (21) 7 29 36 (1) (1) (1) (3) (3) Profit from continuing operations (416) (468) (450) (351) (526) (421) (474) (456) (368) (513) 5 5 6 17 (13) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit (416) (468) (450) (351) (526) (421) (474) (456) (368) (513) 5 5 6 17 (13) Non-controlling interests 0 (0) 0 (1) 10 (0) (1) 0 (1) (1) 0 1 0 0 10 Underlying attributable profit to the parent (415) (469) (450) (352) (517) (421) (475) (456) (369) (514) 6 6 6 17 (3) NEW PREVIOUS DIFFERENCES Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Mar-18 Jun-18 Sep-18 Dec-18 Mar-19 Balance sheet Loans and advances to customers 6,186 7,012 8,627 6,509 6,138 6,186 7,012 6,863 6,508 6,114 1 0 1,764 1 25 Cash, central banks and credit institutions 33,637 39,060 37,010 39,840 26,755 7,395 7,470 11,259 6,141 20,571 26,242 31,589 25,752 33,699 6,184 Debt instruments 1,691 351 330 377 954 1,691 351 330 377 637 — 0 (0) (0) 318 Other financial assets 2,321 2,240 2,185 2,113 2,207 2,321 2,240 2,185 2,113 2,207 — 0 0 (0) 0 Other asset accounts 121,803 120,821 117,833 121,775 132,551 124,409 123,421 120,710 124,494 133,735 (2,607) (2,601) (2,876) (2,720) (1,184) Total assets 165,638 169,484 165,986 170,614 168,605 142,002 140,494 141,346 139,634 163,263 23,636 28,989 24,639 30,980 5,342 Customer deposits 214 231 216 235 163 214 231 215 234 163 0 0 0 0 0 Central banks and credit institutions 23,712 29,012 24,661 30,879 16,920 154 105 108 1 11,588 23,558 28,908 24,552 30,879 5,332 Marketable debt securities 39,223 40,421 42,948 41,783 43,441 39,223 40,421 42,948 41,783 43,441 — — — 0 — Other financial liabilities 1,593 1,622 593 1,334 2,321 1,592 1,621 592 1,333 2,320 2 1 1 1 1 Other liabilities accounts 7,851 7,763 7,923 8,208 8,356 7,849 7,761 7,922 8,206 8,354 2 2 2 2 2 Total liabilities 72,593 79,050 76,341 82,439 71,201 49,031 50,140 51,786 51,557 65,866 23,562 28,911 24,555 30,882 5,336 Total equity 93,045 90,433 89,645 88,175 97,404 92,971 90,355 89,561 88,077 97,398 74 78 84 98 6 Pro memoria: Gross loans and advances to customers ** 6,283 7,134 7,002 6,653 6,414 6,277 7,134 7,002 6,652 6,390 6 0 0 1 25 Customer funds 216 238 222 244 176 216 238 222 243 176 0 0 0 0 0 Customer deposits *** 214 231 216 237 163 214 231 215 237 163 0 0 0 0 0 Mutual funds 2 7 7 7 13 2 7 7 7 13 (0) 0 (0) 0 0

28 ■ Secondary segments

29 RETAIL BANKING (Retail Banking vs Retail Banking + Real Estate Activity Spain) EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 7,962 8,010 7,846 8,443 8,163 8,026 8,062 7,913 8,488 8,209 (65) (52) (67) (45) (46) Net fee income 2,264 2,238 2,051 2,318 2,314 2,283 2,259 2,068 2,334 2,303 (20) (21) (17) (17) 11 Gains (losses) on financial transactions * 135 168 224 229 94 129 134 219 238 102 6 34 5 (9) (8) Other operating income 155 97 148 (57) 76 228 191 209 40 157 (72) (94) (61) (97) (80) Total income 10,516 10,513 10,269 10,933 10,647 10,667 10,646 10,409 11,101 10,771 (151) (132) (140) (167) (124) Administrative expenses and amortisations (4,891) (4,837) (4,498) (5,011) (4,830) (4,934) (4,905) (4,534) (5,076) (4,886) 44 68 36 64 55 Net operating income 5,625 5,677 5,771 5,922 5,817 5,733 5,740 5,875 6,025 5,885 (107) (64) (104) (103) (68) Net loan-loss provisions (2,171) (1,933) (2,050) (2,394) (2,161) (2,170) (1,936) (2,052) (2,373) (2,160) (1) 3 2 (21) (1) Other gains (losses) and provisions (372) (396) (411) (612) (392) (371) (394) (404) (611) (411) (1) (2) (7) (1) 19 Profit before tax 3,082 3,348 3,310 2,915 3,264 3,192 3,410 3,419 3,041 3,314 (109) (63) (109) (126) (51) Tax on profit (989) (1,101) (1,144) (911) (1,093) (1,017) (1,107) (1,164) (937) (1,089) 28 6 21 26 (4) Profit from continuing operations 2,093 2,247 2,166 2,004 2,171 2,175 2,304 2,254 2,104 2,225 (82) (57) (88) (100) (55) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 2,093 2,247 2,166 2,004 2,171 2,175 2,304 2,254 2,104 2,225 (82) (57) (88) (100) (55) Non-controlling interests (306) (357) (318) (291) (367) (308) (360) (321) (296) (362) 2 3 3 5 (6) Underlying attributable profit to the parent 1,787 1,890 1,848 1,713 1,803 1,867 1,944 1,933 1,808 1,864 (80) (54) (85) (94) (60) (*).- Includes exchange differences.

30 (*).- Includes exchange differences. CORPORATE & INVESTMENT BANKING EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 583 558 602 718 653 551 541 573 713 644 31 18 29 5 9 Net fee income 412 407 335 380 353 404 399 330 379 362 8 8 5 1 (9) Gains (losses) on financial transactions * 328 173 236 161 230 342 219 263 179 233 (14) (46) (27) (19) (3) Other operating income 33 67 13 71 57 35 58 29 72 57 (2) 9 (16) (1) — Total income 1,355 1,206 1,185 1,330 1,293 1,332 1,217 1,194 1,343 1,296 23 (11) (9) (13) (3) Administrative expenses and amortisations (524) (514) (510) (553) (560) (527) (503) (524) (551) (560) 3 (11) 14 (2) — Net operating income 831 692 675 777 733 805 715 670 792 736 26 (23) 5 (15) (3) Net loan-loss provisions (70) (55) (41) (32) (10) (71) (49) (42) (56) (10) 0 (6) 1 24 — Other gains (losses) and provisions 1 (38) (19) (41) (21) (2) (39) (24) (43) (21) 3 1 5 2 — Profit before tax 762 598 615 705 703 733 627 604 693 706 29 (28) 11 11 (3) Tax on profit (231) (191) (192) (218) (208) (212) (192) (183) (205) (209) (19) 1 (9) (13) 1 Profit from continuing operations 531 407 424 486 495 521 434 421 488 497 10 (27) 2 (2) (2) Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 531 407 424 486 495 521 434 421 488 497 10 (27) 2 (2) (2) Non-controlling interests (37) (43) (36) (40) (41) (38) (44) (37) (41) (41) 1 1 0 0 — Underlying attributable profit to the parent 494 364 387 446 454 483 390 384 447 457 11 (27) 3 (2) (2)

31 (*).- Includes exchange differences. WEALTH MANAGEMENT & INSURANCE EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 125 131 132 138 140 100 107 104 109 113 25 24 28 30 27 Net fee income 287 296 277 282 276 276 284 266 271 277 11 12 11 12 (1) Gains (losses) on financial transactions * 17 27 35 52 34 9 16 13 25 21 8 12 22 28 13 Other operating income 70 78 70 81 76 (7) (9) (9) (11) (8) 77 87 79 92 85 Total income 499 532 513 554 525 379 398 374 393 402 121 135 139 161 123 Administrative expenses and amortisations (221) (222) (215) (216) (230) (182) (188) (179) (181) (193) (39) (34) (35) (35) (36) Net operating income 279 310 299 338 296 197 210 194 212 209 82 101 104 126 87 Net loan-loss provisions (4) 4 (2) (8) 7 (5) (0) 1 (5) 7 1 4 (3) (3) (0) Other gains (losses) and provisions (2) (2) (2) 2 (3) (1) (4) (5) 2 (3) (1) 1 3 (0) (0) Profit before tax 273 312 294 332 300 191 206 190 209 213 81 106 104 123 87 Tax on profit (64) (71) (68) (81) (70) (57) (59) (54) (64) (64) (6) (13) (14) (17) (6) Profit from continuing operations 209 241 226 252 229 134 147 136 145 149 75 93 90 106 81 Net profit from discontinued operations — — — — — — — — — — — — — — — Consolidated profit 209 241 226 252 229 134 147 136 145 149 75 93 90 106 81 Non-controlling interests (12) (13) (12) (15) (12) (8) (9) (9) (9) (7) (4) (5) (4) (6) (5) Underlying attributable profit to the parent 197 227 214 237 218 126 139 128 136 142 71 88 86 101 76

32 (*).- Includes exchange differences. SANTANDER GLOBAL PLATFORM EUR million NEW PREVIOUS DIFFERENCES Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Q1'18 Q2'18 Q3'18 Q4'18 Q1'19 Underlying income statement Net interest income 18 20 20 20 22 18 20 20 20 22 Net fee income 1 1 1 4 2 1 1 1 4 2 Gains (losses) on financial transactions * 0 0 0 (0) (1) 0 0 0 (0) (1) Other operating income (4) (3) (3) (2) (4) (4) (3) (3) (2) (4) Total income 16 18 19 21 19 16 18 19 21 19 Administrative expenses and amortisations (23) (39) (32) (49) (41) (23) (39) (32) (49) (41) Net operating income (7) (21) (13) (28) (22) (7) (21) (13) (28) (22) Net loan-loss provisions 0 (0) (0) (0) (0) 0 (0) (0) (0) (0) Other gains (losses) and provisions (1) (0) (1) (0) (1) (1) (0) (1) (0) (1) Profit before tax (7) (21) (13) (28) (23) (7) (21) (13) (28) (23) Tax on profit (1) 7 4 7 12 (1) 7 4 7 12 Profit from continuing operations (9) (14) (10) (22) (11) (9) (14) (10) (22) (11) Net profit from discontinued operations — — — — — — — — — — Consolidated profit (9) (14) (10) (22) (11) (9) (14) (10) (22) (11) Non-controlling interests — — — — — — — — — — Underlying attributable profit to the parent (9) (14) (10) (22) (11) (9) (14) (10) (22) (11)

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SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.