Exhibit 12.1
Computation of Ratio of Earnings to Fixed Charges
| Year Ended December 31, | Six Months Ended | |||||||||||||||||||
| 2014 | 2015 | 2016 | 2017 | June 30, 2018 | ||||||||||||||||
| Determination of earnings |
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| Income (loss) before income taxes |
(45,603,110 | ) | (27,561,702 | ) | (45,817,394 | ) | (49,376,875 | ) | (25,741,828 | ) | ||||||||||
| Fixed Charges |
— | — | — | — | — | |||||||||||||||
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| Total income (loss) |
$ | (45,603,110 | ) | $ | (27,561,702 | ) | $ | (45,817,394 | ) | $ | (49,376,875 | ) | $ | (25,741,828 | ) | |||||
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| Fixed charges: |
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| N/A |
— | — | — | — | — | |||||||||||||||
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| Total fixed charges |
— | — | — | — | — | |||||||||||||||
| Ratio of earnings to fixed charges |
N/A | N/A | N/A | N/A | N/A | |||||||||||||||
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| (Deficiency) excess of earnings to cover fixed charges |
$ | (45,603,110 | ) | $ | (27,561,702 | ) | $ | (45,817,394 | ) | $ | (49,376,875 | ) | $ | (25,741,828 | ) | |||||
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